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Crizotinib primary resistance overcome by ceritinib in a patient with ALK-rea...

Facchinetti(Francesco),Caramella(Caroline)... Tumori 0000-00-00

...ALK) gene rearrangement who did not respond to crizotinib but subsequently benefited from treatment with ceritinib (LDK3...

Identification of driver mutations in tumor specimens from 1,000 patients wit...

Kris(M G),Johnson(B E),Kwiatkowski(D J),Ia... J Clin Oncol 0000-00-00

CRA7506 Background: The ability to detect driver mutations like EGFR and EML4-ALK in tumor specimens from patients with ...

Clinical activity of the oral ALK inhibitor PF-02341066 in ALK-positive patie...

Bang(Y),Kwak(E L),Shaw(A T),Camidge(D R),I... J Clin Oncol 0000-00-00

...ALK and MET/HGF receptor tyrosine kinases. EML4-ALK fusion oncogenes have been reported in approximately 4% of NSCLC. Pa...

MAGE-A family expression is correlated with poor survival of patients with lu...

Sang(Meixiang),Gu(Lina),Yin(Danjing),Liu(F... J Clin Pathol 0000-00-00

...ALK rearrangements, but not affect the overall survival of patients with LAC and EGFR amplification or ALK rearrangement...

W'ALK' Into the Next Stage.

Toyokawa(Gouji),Seto(Takashi),Takenoyama(M... Clin Lung Cancer 0000-00-00

...ALK rearrangement in lung cancer, the first-in-class ALK inhibitor (ALKi), crizotinib, was approved for metastatic ALK-r...

Clinical Impact of Hybrid Capture-Based Next-Generation Sequencing on Changes...

Rozenblum(Anna Belilovski),Ilouze(Maya),Du... J Thorac Oncol 0000-00-00

...ALK) testing. Next-generation sequencing (NGS) reveals more actionable genomic alterations than do standard diagnostic m...

Enigmas in tumor resistance to kinase inhibitors and calculation of the drug ...

Smith(C I Edvard) Semin Cancer Biol 0000-00-00

...ALK, BCR-ABL, BRAF, BTK, and EGFR. A key therapeutic challenge is how to reduce tumor growth after treatment, since this...

Pediatric case of anaplastic lymphoma kinase-positive anaplastic large cell l...

Tokuyama(Michio),Kurashige(Yuta),Ota(Tami)... J Dermatol 0000-00-00

...ALK and multiple lymphadenopathy, we diagnosed ALK-positive ALCL forming a solitary skin tumor on the forearm. The patie...

Intraosseous inflammatory myofibroblastic tumor of the mandible with a novel ...

Tateishi(Yoko),Okudela(Koji),Kawai(Shigeo)... Diagn Pathol 0000-00-00

...ALK by immunohistochemistry. A fluorescence in situ hybridization analysis revealed the translocation of a part of the A...

Pooled Analysis of CNS Response to Alectinib in Two Studies of Pretreated Pat...

Gadgeel(Shirish M),Shaw(Alice T),Govindan(... J Clin Oncol 0000-00-00

...ALK-positive non-small-cell lung cancer (NSCLC). Patients and Methods Both studies included patients with ALK-positive N...

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