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Mechanism-Guided Design and Synthesis of a Mitochondria-Targeting Artemisinin...

Zhang(Chong-Jing),Wang(Jigang),Zhang(Jianb... Angew Chem Int Ed Engl 0000-00-00

...Alk was also employed to confirm that the attachment of the TPP group could label more mitochondrial proteins than that ...

[Expression of ALK protein in 7 371 pulmonary adenocarcinoma samples, with an...

Zhao(R Y),Zhang(J),Zhu(L),Shao(J C),Zhang(... Zhonghua Bing Li Xue Za Zhi 0000-00-00

...ALK protein using Ventana ALK (D5F3) kit was carried in 7 371 pulmonary adenocarcinoma samples. The clinicopathologic fe...

[Clinicopathologic features and epidermal growth factor receptor gene mutatio...

Huang(Y),Wu(C Y),Wu(W),Hou(L K),Zhang(L P) Zhonghua Bing Li Xue Za Zhi 0000-00-00

...ALK (Ventana D5F3) in all 55 cases. The tumor cells were positive for CK7, and some squamous and intermediate cells were...

How the lab is changing our view of colorectal cancer.

Cremolini(Chiara),Pietrantonio(Filippo) Tumori 0000-00-00

...ALK, ROS and NTRK1-3 rearrangements as positive predictors of benefit from biological agents is reviewed and discussed.

Mutant form C115H of Clostridium sporogenes methionine γ-lyase efficiently cl...

Kulikova(Vitalia V),Anufrieva(Natalya V),R... IUBMB Life 0000-00-00

...alk(en)yl-l-cysteine sulfoxides to thiosulfinates, which possess antimicrobial activity. Partial inactivation of the enz...

[Lung adenocarcinoma with concomitant EGFR mutation and ALK rearrangement].

Caliez(J),Monnet(I),Pujals(A),Rousseau-Bus... Rev Mal Respir 0000-00-00

Among patients with non-small-cell lung cancer, coexistence of EGFR mutation and ALK rearrangement is rare. We describe ...

Sensitivity Analysis of the NPM-ALK Signalling Network Reveals Important Path...

Buetti-Dinh(Antoine),O'Hare(Thomas),Friedm... PLoS One 0000-00-00

...ALK) is fused to nucleophosmin (NPM) resulting in a constitutively active signalling fusion protein, NPM-ALK. We computa...

Biopsy Procedures and Molecular Testing Utilization and Related Costs in Pati...

Shinde(Reshma),Cao(Xiting),Kothari(Smita) J Manag Care Spec Pharm 0000-00-00

...ALK) gene rearrangements are key therapeutic targets for biomarker-driven treatment with an EGFR or ALK tyrosine kinase ...

Synergistic activity of ALK and mTOR inhibitors for the treatment of NPM-ALK ...

Redaelli(Sara),Ceccon(Monica),Antolini(Lau... Oncotarget 0000-00-00

...ALK/MET inhibitor. Crizotinib blocks ALK-triggered pathways such as PI3K/AKT/mTOR, indispensable for survival of ALK-dri...

miR-200c regulates crizotinib-resistant ALK-positive lung cancer cells by rev...

Gao(Hai-Xiang),Yan(Li),Li(Chunzhi),Zhao(Li... Mol Med Rep 0000-00-00

Crizotinib is an orally administered drug for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive l...

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