...ALK, a comprehensive phosphoproteome analysis of ALCL cell lines was performed in the presence or absence of NPM-ALK act...
...ALK-positive, advanced NSCLC who have previously received the first-generation ALK inhibitor crizotinib (indication deta...
...ALK) positivity was detected in six cases, negative in two cases, and was not evaluated in three cases. Two cases who ha...
...ALK+ LBCL) is a rare distinct type of non-Hodgkin's lymphoma that arises in association with alterations of the ALK gene...
...ALK) gene translocation (the fusion gene, EML4-ALK) was approved, and those targeting lung cancers addicted ROS1, RET, a...
...ALK, reduction of downstream phosphorylation of AKT and ERK, and up-regulation of Hsp70. Molecular docking suggested tha...
...ALK-inhibitors were developed. Second-generation ALK inhibitors Ceritinib (LDK378), Alectinib (CH5424802/RO5424802) and ...
...ALK) gene rearrangement, thyroidlike follicular RCC, and RCC in neuroblastoma survivors. For each RCC subtype, relevant ...
...ALK) positive, i.e. exhibiting the ALK rearrangement, and comprise 3-7% of non-small-cell lung cancer (NSCLC) cases. Thr...
...ALK translocation (2%) distinguish additional cases. Altogether, this study reveals distinct molecular subsets for 76% o...
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