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NPM-ALK phosphorylates WASp Y102 and contributes to oncogenesis of anaplastic...

Murga-Zamalloa(C A),Mendoza-Reinoso(V),Sah... Oncogene 0000-00-00

...ALK, a comprehensive phosphoproteome analysis of ALCL cell lines was performed in the presence or absence of NPM-ALK act...

Ceritinib: a Review in ALK-Positive Advanced NSCLC.

Deeks(Emma D) Target Oncol 0000-00-00

...ALK-positive, advanced NSCLC who have previously received the first-generation ALK inhibitor crizotinib (indication deta...

Surgical Treatment of Childhood Inflammatory Myofibroblastic Tumors.

Soyer(Tutku),Talim(Beril),Karnak(İbrahim),... Eur J Pediatr Surg 0000-00-00

...ALK) positivity was detected in six cases, negative in two cases, and was not evaluated in three cases. Two cases who ha...

Anaplastic lymphoma kinase positive large B-cell lymphoma: Literature review ...

Sakr(Hany),Cruise(Michael),Chahal(Prabhlee... Diagn Cytopathol 0000-00-00

...ALK+ LBCL) is a rare distinct type of non-Hodgkin's lymphoma that arises in association with alterations of the ALK gene...

Developments for Personalized Medicine of Lung Cancer Subtypes: Mass Spectrom...

Nishimura(Toshihide),Nakamura(Haruhiko) Adv Exp Med Biol 0000-00-00

...ALK) gene translocation (the fusion gene, EML4-ALK) was approved, and those targeting lung cancers addicted ROS1, RET, a...

Design, synthesis and pharmacological evaluation of 4,5-diarylisoxazols beari...

Zhang(Chi),Wang(Xin),Liu(Hongchun),Zhang(M... Eur J Med Chem 0000-00-00

...ALK, reduction of downstream phosphorylation of AKT and ERK, and up-regulation of Hsp70. Molecular docking suggested tha...

Current and developing therapies for the treatment of non-small cell lung can...

Caccese(M),Ferrara(R),Pilotto(S),Carbognin... Expert Opin Pharmacother 0000-00-00

...ALK-inhibitors were developed. Second-generation ALK inhibitors Ceritinib (LDK378), Alectinib (CH5424802/RO5424802) and ...

Morphologic, Molecular, and Taxonomic Evolution of Renal Cell Carcinoma: A Co...

Udager(Aaron M),Mehra(Rohit) Arch Pathol Lab Med 0000-00-00

...ALK) gene rearrangement, thyroidlike follicular RCC, and RCC in neuroblastoma survivors. For each RCC subtype, relevant ...

Drug resistance in ALK-positiveNon-small cell lungcancer patients.

Qian(Mengjia),Zhu(Bijun),Wang(Xiangdong),L... Semin Cell Dev Biol 0000-00-00

...ALK) positive, i.e. exhibiting the ALK rearrangement, and comprise 3-7% of non-small-cell lung cancer (NSCLC) cases. Thr...

Molecular analysis of aggressive renal cell carcinoma with unclassified histo...

Chen(Ying-Bei),Xu(Jianing),Skanderup(Ander... Nat Commun 0000-00-00

...ALK translocation (2%) distinguish additional cases. Altogether, this study reveals distinct molecular subsets for 76% o...

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