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Targeted Resequencing of 30 Genes Improves the Detection of Deleterious Mutat...

Rajkumar(Thangarajan),Meenakumari(Balaiah)... Asian Pac J Cancer Prev 2016-05-05

...RAD52, ATM and TP53BP1. Some 19 deleterious mutations were seen in patients who had been tested earlier with PCR-dHPLC [...

Curcumin-Mediated HDAC Inhibition Suppresses the DNA Damage Response and Cont...

Wang(Shu-Huei),Lin(Pei-Ya),Chiu(Ya-Chen),H... PLoS One 2016-05-03

...Rad52 recombinase is degraded by curcumin, which results in deficiencies in double-stand break repair. Additive effects ...

The Replisome-Coupled E3 Ubiquitin Ligase Rtt101Mms22 Counteracts Mrc1 Functi...

Buser(Raymond),Kellner(Vanessa),Melnik(And... PLoS Genet 2016-07-19

...Rad52-dependent mechanism. Our results suggest that the Rtt101(Mms22) E3 ligase does not induce Mrc1 degradation, but sp...

Structure and mechanism of the phage T4 recombination mediator protein UvsY.

Gajewski(Stefan),Waddell(Michael Brett),Va... Proc Natl Acad Sci U S A 2016-09-09

...Rad52 protein. During T4 homologous recombination, the UvsX recombinase has to compete with the prebound gp32 single-str...

Functional Validation of Rare Human Genetic Variants Involved in Homologous R...

Lee(Min-Soo),Yu(Mi),Kim(Kyoung-Yeon),Park(... PLoS One 2016-04-04

...Rad52. The rad51-F317I, rad52-R52W, and rad52-G107C mutations conferred hypersensitivity to methyl methane sulfonate (MM...

Ku stabilizes replication forks in the absence of Brc1.

Sánchez(Arancha),Russell(Paul) PLoS One 2016-02-01

...Rad52 homologous recombination (HR) protein increase and Mus81-Eme1 Holliday junction resolvase becomes critical, indica...

Recombination-Mediated Telomere Maintenance in Saccharomyces cerevisiae Is No...

van Mourik(Paula M),de Jong(Jannie),Agpalo... PLoS One 2016-08-08

...Rad52-dependent homologous recombination and Pol32-dependent break-induced replication. There are two main types of surv...

Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Sele...

Sullivan(Katherine),Cramer-Morales(Kimberl... PLoS One 2016-08-09

...RAD52. Thirty six lead candidate compounds were identified that were predicted to interfere with RAD52 -DNA binding. Fur...

Swi1Timeless Prevents Repeat Instability at Fission Yeast Telomeres.

Gadaleta(Mariana C),Das(Mukund M),Tanizawa... PLoS Genet 2016-08-03

...Rad52 recombinase and more frequent amplification of telomere/subtelomeres, reminiscent of tumor cells that utilize the ...

[Dot1 and Set2 Histone Methylases Control the Spontaneous and UV-Induced Muta...

Kozhina(T N),Evstiukhina(T A),Peshekhonov(... Genetika 2016-09-23

...rad52 mutations revealed a considerable level of spontaneous cell death in the double dot1 rad52 mutant. We observed str...

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