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Sakai(H),Kusumoto-Matsuo(R),Hosonaga(M),No... Breast Cancer 2026-05-00

...BRCA2 mutation. In one patient, BRCA2 reversion mutations were found in ctDNA seven months before radiological confirmat...

Fagbohun(OF),Oladipo(AO),Gao(C),Olawoye(B)... Cell Death Discov 2026-04-10

...BRCA2, BARD1, CDH1, NF1, and CHEK2) and deciphered the functional consequences leveraging the higher throughput Illumina...

Hörner(M),Hartkopf(A),John(N),Ziegler(P),H... NPJ Breast Cancer 2026-04-11

Germline BRCA1 and BRCA2 mutations enable targeted therapies in human epidermal growth factor receptor 2 (HER2)-negative...

Quinto Pereira(M),Miguel(I),Fragoso(S),Dua... Cureus 2026-03-00

...BRCA2 was the most frequently affected gene (37 patients), with the BRCA2 Portuguese founder variant (c.156_157insAlu) i...

Georgy(DM),Sedeek(HN),Abaza(NE),Eldeeb(SEK... Biochem Biophys Rep 2026-06-00

The Breast Cancer gene 1 (BRCA1) and Breast Cancer gene 2 (BRCA2) genes are pivotal human tumor suppressor genes that ar...

Liu(M),Gao(P),Liu(F),Li(D),Wang(Y),Yu(J) Front Oncol None

...BRCA2 mutation. After failing several therapies, the disease progressed to a histologically confirmed small-cell lung ca...

Matsuoka(T),Akamatsu(S),Ong(CJ),Gleave(ME)... Cells 2026-03-26

...BRCA2, and most responders eventually relapse. Here, we frame PARPi response and resistance through a unifying model in ...

Balkwill(FR),Laumont(CM),Burdett(N),Le Sau... Nat Rev Cancer 2026-06-00

...BRCA2 (BRCA1/BRCA2) mutations of any cancer type and is a highly chromosomally unstable disease. Despite the introductio...

Prihharsanti(CHN),Prajoko(YW),Respati(DRP)... Cancers (Basel) 2026-03-29

...BRCA2, CHEK2, and ATM. While radiotherapy (RT) is a crucial component of breast cancer (BC) treatment, its potential rol...

Di Costanzo(F),Williamson(J),Robson(CN),Ga... Mol Cancer Ther 2026-04-02

...BRCA2 gene mutations, whereas their role in tumors with alterations of DNA repair genes other than BRCA1/2 and proteins ...