...TP53 mutation/17p loss (Sonic Hedgehog, SHH), MYC amplification (group_3), and CDK6 activation (group_4), were strongly ...
...TP53 and TET2 in ENI-endoderm, and MYD88, PIM1, TBL1XR1, and CD79B in ENI-mesoderm. Notably, organotrophic migration exh...
...TP53 mutations in two cases, RB1 inactivation in the mixed tumour. Gallbladder carcinomas may rarely exhibit acinar diff...
...TP53 and PTEN. To advance our understanding of the role of specific genomic alterations in PCa, genetically engineered m...
...TP53 alterations. These cases illustrate the pleiotropic role of DICER1 in renal tumorigenesis and the histologic hetero...
...TP53 mutations, MDS diagnosis, and higher-risk disease were associated with worse progression-free and overall survival;...
...TP53, STAT3, and IL6, with biological processes related to oxidative stress. Further investigations show that DXR signif...
...TP53) NM_000546.6:c.730G>T (p.Gly244Cys) and platelet-derived growth factor receptor alpha (PDGFRA) NM_006206.6:c.2525A>...
...TP53-mutant B-cell ALL, which necessitate tailored therapies. We explore novel strategies such as BH3 mimetics, menin in...
...TP53 mutations (n = 9).Approximately 40% of patients with relapsed myeloid malignancies were successfully salvaged with ...
山东省济南市章丘区文博路2号
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