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Xu(X),Chen(X),Xu(R),Huo(Z),Li(C),Nowsheen(... Nat Commun 2026-02-24

...BRCA1, RAD51, and RPA32, creating a state of HR deficiency that sensitizes PDAC cells to poly(ADP-ribose) polymerase (PA...

Nakamura(Y),Daino(K),Ishikawa(A),Kakinuma(... Sci Rep 2026-02-24

...BRCA1/2 have a high risk of breast cancer. Although recent research has suggested that genomic instability via BRCA1/2 h...

Fan(J),Song(Y) PeerJ None

...BRCA1/2-associated breast cancer. With ongoing research, PARP inhibitors (PARPi) are currently under extensive investiga...

Sánta(ÁT),Gráf(A),Vincze-Kontár(K),Kovács(... NAR Cancer 2026-03-00

...BRCA1 and RAD18 genes. Combining IGIS with cell survival, DNA fibre, BrdU alkaline comet assays, and pRPA immunostaining...

Qin(DY),Tang(QQ),Feng(D),Song(YJ),Cheng(ZH... Front Pediatr None

...BRCA1-associated ataxia telangiectasia mutated activator 1 (BRAT1) gene mutations can result in lethal neonatal rigidity...

Sengupta(A),Saha(P),Chakraborty(R),Maiti(A... Apoptosis 2026-02-20

...BRCA1/2, TP53), to environmental determinants as well. Prognostic biomarkers now lead precision medicine: PR, ER, and HE...

Nusawardhana(A),Nicolae(CM),Moldovan(GL) Nat Commun 2026-02-25

...BRCA1 and BRCA2 genes are observed in breast, ovarian, and other cancers. This results in defective homologous recombina...

Witjes(VM),de Hullu(JA),van Remortele(A),V... Virchows Arch 2026-04-00

...BRCA1/RAD51C promoter methylation and HRD was assessed in 244 samples without a PV in HRR genes. BRCA1/RAD51C promoter m...

Pimenova(M),Rosenbaum(MW) Semin Diagn Pathol 2026-03-00

...BRCA1/2, and others may aid in diagnosis, prognostication, and the selection of targeted therapeutic options. By systema...

Pasanisi(J),Lamy(C),Lecompte(L),Vacher(S),... NPJ Breast Cancer 2026-02-07

...BRCA1 methylation, genomic alterations, HRD and outcomes. Constitutional BRCA1 methylation was detected in 20.6% of pati...