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DNA repair pathways involved in repair of lesions induced by 5-fluorouracil a...

Matuo(Renata),Sousa(Fabrício Garmus),Escar... Biochem Pharmacol 2009-12-07

...rad52) and PPR (rad6, rad18) were associated with increased sensitivity to 5-FU, but not to FdUMP. Taken together, our s...

Second-end capture in DNA double-strand break repair promoted by Brh2 protein...

Mazloum(Nayef),Holloman(William K) Mol Cell 2009-03-04

...Rad52, or when the second single-stranded DNA substrate is replaced by double-stranded DNA. In a coupled reaction that r...

Redundant roles of Srs2 helicase and replication checkpoint in survival and r...

Yasuhira(Shinji) Mol Genet Genomics 2009-05-28

...RAD52 failed to rescue the growth, suggesting that events that impose lethality are independent of homologous recombinat...

Rad52 promotes second-end DNA capture in double-stranded break repair to form...

Nimonkar(Amitabh V),Sica(R Alejandro),Kowa... Proc Natl Acad Sci U S A 2009-04-01

...Rad52, cannot form complement-stabilized joint molecules with RPA-ssDNA complexes, nor can Rad52 promote second-end capt...

Suppression of a DNA polymerase delta mutation by the absence of the high mob...

Kim(Haeyoung),Livingston(Dennis M) Curr Genet 2009-05-22

...RAD52-mediated repair, their suppression is independent in that both can suppress in the presence of the other. We concl...

Rrm3 protects the Saccharomyces cerevisiae genome from instability at nascent...

Stamenova(Radostina),Maxwell(Patrick H),Ke... Genetics 2009-09-25

...Rad52-dependent mechanism that did not involve gene conversion of genomic Ty1 sequences. In rrm3 isolates, incorporated ...

Homologous recombinational repair factors are recruited and loaded onto the v...

Kudoh(Ayumi),Iwahori(Satoko),Sato(Yoshitak... J Virol 2009-06-18

...Rad52 as well as MRN complexes are recruited and loaded onto the newly synthesized viral genome in replication compartme...

A two-step model for senescence triggered by a single critically short telomere.

Abdallah(Pauline),Luciano(Pierre),Runge(Ku... Nat Cell Biol 2009-09-21

...RAD52 (radiation sensitive) and MMS1 (methyl methane sulfonate sensitive), and there is no evidence for major inter-telo...

The DNA damage response at eroded telomeres and tethering to the nuclear pore...

Khadaroo(Basheer),Teixeira(M Teresa),Lucia... Nat Cell Biol 2009-09-21

...Rad52 into a single focus. Moreover, we show that eroded telomeres, although remaining at the nuclear periphery, move to...

Vorinostat inhibits brain metastatic colonization in a model of triple-negati...

Palmieri(Diane),Lockman(Paul R),Thomas(Fan... Clin Cancer Res 2009-12-22

...Rad52.,We report the first preclinical data for the prevention of brain metastasis of triple-negative breast cancer. Vor...

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