Tanaka(Y),Ikenoue(S),Ueno(A),Masugi(Y),Yamad… Eur J Med Genet 2025-10-00

...RIT1-associated mirror syndrome and non-immune hydrops fetalis (NIHF) further supports the role of Rasopathies in the pa...

Guo(R),Duan(C),Zarrei(M),Reuter(MS),Dong(R),… Sci Rep 2025-07-26

...RIT1, and SMAD6. Trio sequencing facilitated the identification of pathogenic variation (55.6% were de novo missense var...

DiMarco(AV),Ravichandran(M),Lau(J),Lima(A),L… Cancer Res 2025-09-02

...RIT1 alterations. In this study, we generated a murine model of RIT1M90I-mutant lung cancer. RIT1M90I expression induced...

Mozzarelli(AM),Cuevas-Navarro(A),Shuldiner(E… Cancer Res 2025-09-02

RIT1 is a small GTPase of the RAS family, and RIT1 mutations have been identified in lung cancer, leukemia, and the deve...

Wu(CP),Vaishnavi(A) Cancer Res 2025-09-02

...RIT1-mutant lung tumors to SHP2 or RAS tricomplex inhibitors. Collectively, these findings highlight the importance of R...

Yu(QX),Zhen(L),Zhang(YL),Li(SY),Li(R),Li(DZ) Eur J Obstet Gynecol Reprod B… 2025-11-00

...RIT1, SHOC2, and SOS1. The most significant contributor among these variants was PTPN11 (43.7 %; 31/71), followed by RAF...

Yeung(Sai F),Tong(Joanna H M),Law(Peggy P W)… J Thorac Oncol 2016-06-13

...RIT1 mutations by polymerase chain reaction-direct sequencing. MET amplification and ALK and ROS1 translocations were as...

Yaoita(Masako),Niihori(Tetsuya),Mizuno(Seiji… Hum Genet 2016-05-20

...RIT1 mutation-positive patients, we further performed a RIT1 analysis in RASopathy patients and identified 7 RIT1 mutati...

Čizmárová(M),Hlinková(K),Bertok(S),Kotnik(P)… Ann Hum Genet 2016-05-31

...RIT1, one in SHOC2, two in HRAS, three in BRAF, two in MAP2K1 and two in the NF1 gene). Two of them (p.Gly392Glu in the ...

Xu(Fengjuan),Sun(Su'an),Yan(Shilan),Guo(Hong… Int J Clin Exp Pathol 2016-10-05

...RIT1 and assess the clinical significance of RIT1 expression in endometrial cancer patients. The mRNA and protein expres...