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Olaparib for patients with tumors harboring alterations in homologous recombina…

Spiekman(IAC),Mehra(N),Zeverijn(LJ),Geurts(B… Int J Cancer 2026-03-15

...RAD51B (cohort B). Primary endpoints were clinical benefit (CB: confirmed objective response or stable disease ≥16 weeks...

High burden of variants of uncertain significance in early-onset colorectal can…

Yildiz(S),Chambuso(R),Rebello(G),Ramesar(R) Mol Biol Rep 2025-07-08

...RAD51B, RAD54L, RASA1, RECQL, SUFU, VEGFA, and WT1. Comparative analysis with public datasets and recurrent findings sug...

Comprehensive RAD51C ovarian cancer variant analysis uncouples homologous recom…

Rein(HL),Rawal(Y),Palovcak-Lightbourn(AL),Ga… Nat Commun 2025-07-16

...RAD51B-C-D-XRCC2 (BCDX2) complex. With yeast 3-hybrid and biochemical analyses, we identify a mutation cluster of the RA...

Genomic landscape of endometrial polyps.

Reinikka(S),Mehine(M),von Nandelstadh(P),Ahv… Genome Med 2025-10-24

...RAD51B, TRAF3IP2, and 7p15.2 as recurrent rearrangement partners. 3'RNA sequencing indicated corresponding overexpressio...

Detection of novel germline mutations for breast cancer in non-BRCA1/2 families.

Aloraifi(Fatima),McDevitt(Trudi),Martiniano(… FEBS J 2016-02-25

...RAD51B, ZNF217, CDKN2B-AS1, and ERBB2, including a splice site mutation, which we predict would generate a constitutivel...

Screening of HELQ in breast and ovarian cancer families.

Pelttari(Liisa M),Kinnunen(Laura),Kiiski(Joh… Fam Cancer 2016-10-05

...RAD51B and XRCC2 have been associated with breast cancer risk. To investigate the role of HELQ in cancer predisposition,...

Polymorphisms of homologous recombination RAD51, RAD51B, XRCC2, and XRCC3 genes…

Nowacka-Zawisza(Maria),Wiśnik(Ewelina),Wasil… Anal Cell Pathol (Amst) 2016-06-06

...RAD51B (rs10483813 and rs3784099), XRCC2 (rs3218536), and XRCC3 (rs861539). Polymorphisms were analyzed by PCR-RFLP and ...

Genomic landscape of human papillomavirus-associated cancers.

Rusan(Maria),Li(Yvonne Y),Hammerman(Peter S) Clin Cancer Res 2016-03-31

...RAD51B, NR4A2, and TP63, leading to aberrant forms of these proteins, are observed in both HPV-positive head and neck sq...

Adherence to a Mediterranean diet, genetic susceptibility, and progression to a…

Merle(Bénédicte M J),Silver(Rachel E),Rosner… Am J Clin Nutr 2016-02-08

...RAD51B)] were examined. Survival analysis was used to assess individual eyes for associations between incident AMD and a...

Integrated Genome-wide association and hypothalamus eQTL studies indicate a lin…

Ponsuksili(Siriluck),Zebunke(Manuela),Murani… Sci Rep 2016-09-23

...RAD51B, UBOX5) had cis- and five (RANGRF, PER1, PDZRN3, SH2D4B, LONP2) had trans-expressionQTL. In particular, for PER1,...

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