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Huang(Y),Gao(Y),Duan(Z),Jia(X),Sun(Y),Liu(... NPJ Genom Med 2026-04-02

...BRCA2. Importantly, 28 variants across 12 genes showed significant allele frequency divergence between Chinese and Europ...

Lin(JH),Wu(H),Tang(XY),Masson(E),Stenson(P... HGG Adv 2026-07-09

...BRCA2 c.8331+2T>C, illustrating how intermediate splicing effects complicate clinical interpretation across distinct gen...

Terrano(V),Perri(E),Cioffo(C),Mastroianni(... Int Cancer Conf J 2026-04-00

...BRCA2, ATM, and TP53. Due to the high TMB, off-label Pembrolizumab was initiated. Radiological evaluations at 3 and 6 mo...

Corso(G),Andreon(C),La Vecchia(C),Bottazzo... Eur J Cancer 2026-05-15

...BRCA2 (SOR=1.28, 95%CI (0.95-1.72)). The difference between the association with BRCA1 and BRCA2 was statistically signi...

Chapman(IG),Wu(X),Veuger(S),Jowsey(PA) PLoS One None

...BRCA2 and RAD51 to DNA double strand breaks (DSBs) during HRR, though the magnitude of this defect in human cells is not...

Zhao(Q),Li(N),Marinovic(E),McInerny(S),Zet... NPJ Breast Cancer 2026-04-04

Pathogenic coding variants in BRCA1, BRCA2 and PALB2 confer hereditary breast/ovarian cancer risk, yet these regions com...

Milano(L),Wells(S),Vaitsiankova(A),Drummon... Mol Cell 2026-04-16

...BRCA2 and is associated with the BRCA2-dependent accumulation of RAD51 recombinase in chromatin. Our data identify nasce...

Barsch(M),Godbole(I),Metzger(P),Benzing(M)... ESMO Gastrointest Oncol 2026-06-00

...BRCA2-mutated BTC together with a positive HRD score was sensitive to platinum-based therapy and poly (ADP-ribose) polym...

Lin(C),Hu(J),Cai(F),Chen(J),Huang(J),Lin(Y... Curr Med Chem 2026-03-18

...BRCA2, and ESR1 as key hub genes. These genes were upregulated in tumors, showing robust diagnostic performance (AUC>0.7...

Zeng(Z),Gandini(A),Bhatt(R),Proctor(M),Goh... Br J Cancer 2026-06-00

...BRCA2 mutation and homologous recombination repair status in vitro. In vivo, treatment significantly reduced tumour burd...