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A novel approach to silver nanoparticle biosynthesis using ursolic acid from ...

Raguvaran(K),Kamatchi(PAC),Handayani(M),Ka... Sci Rep 2026-02-16

...BRCA1 and C-erbB2 and bacterial virulence proteins Hbl and aglD. These findings highlight the bio efficacy of UA-AgNPs a...

Homologous recombination deficiency in primary ER-positive and HER2-negative ...

Davies(HR),Black(D),Kvist(A),Sigurjónsdótt... Commun Med (Lond) 2026-02-16

Homologous recombination deficiency (HRD) originating from inactivation of genes like BRCA1/BRCA2 is a targetable abnorm...

Quantifying rate-limiting genetic variation in breast and ovarian tumourigene...

Houlahan(KE),Bihie(M),Greatti(Y),Contreras... EBioMedicine 2026-03-00

...BRCA1/2 carriers show markedly elevated cancer risk, it is uncertain whether point mutations or copy number alterations ...

Preimplantation genetic testing for BReast CAncer gene 1 and risk-reducing su...

Hunkler(K),Boedeker(D),Bulles(K),Combs(J),... Fertil Steril 2026-06-00

...BRCA1 (BReast CAncer gene 1) mutation carriers. A cost-effectiveness analysis using a Markov mathematical model. Probabi...

BAP1 Loss Induces Senescence and Enhances the Response to Radiation Therapy a...

Elsayed(AM),Mosbeh(A),Eltasawi(EG),Hanpude... bioRxiv 2026-02-09

...BRCA1-associated protein 1 (BAP1) are observed in approximately 45% of primary and ~85% of metastatic uveal melanoma (UM...

Insights into the olaparib-mediated cell death mechanisms in canine hematolog...

Mucignat(G),Dejnaka(E),Pauletto(M),Loppare... Front Vet Sci None

...BRCA1/2 mutations. Recent evidences suggest that sensitivity to PARPis may also be influenced by other factors that impa...

Aggressive Right-Sided Colon Cancer in a Young Adult: Triple-Whammy Mutations...

Patel(R),Kumar(G),Shah(Y),Singh Dahiya(D),... ACG Case Rep J 2026-02-00

...BRCA1. Dual BRCA1/2 pathogenic variants in CRC remain exceptionally rare. We report a case of early-onset CRC in a young...

Prevalence and spectrum of homologous recombination repair mutations in patie...

Baskarane(H),Jain(R),Divakar(MK),Seth(A),N... Oncologist 2026-03-06

...BRCA1 (5.3%), BRCA2 (4.2%), and CDK12 (4.2%). Variants of unknown significance (VUS) were detected in 12% (20) of patien...

Development of cardiovascular risk factors in women with a BRCA1/2 pathogenic...

Gootzen(TA),van Gelder(MMHJ),Hermens(RPMG)... Maturitas 2026-04-00

The effects of risk-reducing salpingo-oophorectomy on the development of cardiovascular risk factors in women with BRCA1...

Integrating germline and tumor sequencing to improve hereditary cancer diagno...

de Voer(RM),Valle(L) Eur J Hum Genet 2026-02-23

...BRCA1/2-deficient tumors and immune checkpoint inhibitors for MMR- and polymerase proofreading-deficient cancers. Tumor ...

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