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Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in ...

Liu(Nan),Schild(David),Thelen(Michael P),T... Nucleic Acids Res 2002-03-04

...XRCC2 and Rad51C-XRCC3. In addition, we demonstrate that Rad51 co-precipitates with XRCC3 but not with XRCC2 or Rad51D, ...

Aneuploidy, centrosome activity and chromosome instability in cells deficient...

Griffin(Carol S) Mutat Res 2002-09-11

...XRCC2 and XRCC3 have an elevated frequency of aneuploidy compared with wild-type cells and mutant cells transfected with...

Variants in DNA double-strand break repair genes and breast cancer susceptibi...

Kuschel(Bettina),Auranen(Annika),McBride(S... Hum Mol Genet 2002-08-30

...XRCC2 and XRCC3) and non-homologous end-joining (KU70/80 and LIG4). These DNA double-strand break repair genes are candi...

A potential role for the XRCC2 R188H polymorphic site in DNA-damage repair an...

Rafii(Saeed),O'Regan(Paul),Xinarianos(Geor... Hum Mol Genet 2002-08-30

...XRCC2, are essential components of this repair pathway. Using site-directed mutagenesis of XRCC2, we show that non-conse...

Effects of double-strand break repair proteins on vertebrate telomere structure.

Wei(Chao),Skopp(Rose),Takata(Minoru),Taked... Nucleic Acids Res 2002-07-19

...XRCC2 or XRCC3. The effect of Rad51 depletion was unexpected because gross alterations in telomere structure have not be...

Identification and purification of two distinct complexes containing the five...

Masson(J Y),Tarsounas(M C),Stasiak(A Z),St... Genes Dev 2002-01-22

Cells defective in any of the RAD51 paralogs (RAD51B, RAD51C, RAD51D, XRCC2, and XRCC3) are sensitive to DNA cross-linki...

Homologous pairing and ring and filament structure formation activities of th...

Kurumizaka(Hitoshi),Ikawa(Shukuko),Nakada(... J Biol Chem 2002-06-07

...Xrcc2 and Rad51D/Rad51L3 proteins (Xrcc2 and Rad51D, respectively) in Escherichia coli, and purified the Xrcc2*Rad51D co...

Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid c...

Godthelp(Barbara C),Wiegant(Wouter W),van ... Nucleic Acids Res 2002-05-28

...Xrcc2 and Xrcc3, which are also implicated in recombination and genome stability. Here, we identify a mammalian cell mut...

RAD51C interacts with RAD51B and is central to a larger protein complex in vi...

Miller(Kristi A),Yoshikawa(Daniel M),McCon... J Biol Chem 2002-04-15

...XRCC2, and XRCC3. However, our experiments showed no evidence for the inclusion of RAD51 within these complexes. Further...

Homologous recombination as a potential target for caffeine radiosensitizatio...

Asaad(N A),Zeng(Z C),Guan(J),Thacker(J),Il... Oncogene 2001-01-04

...XRCC2. Despite the reduced radiosensitization, caffeine effectively abrogates checkpoints in S and G2 phases in XRCC2 mu...

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