...BRCA2 function are linked to hereditary breast and ovarian cancers. As BRCA1 and BRCA2 are critical for homologous recom...
...BRCA2, CDH1, CHEK2, EPCAM, PALB2, and PMS2 are more strongly associated with ILC - to varying degrees. [p < 0.001]. Addi...
...BRCA2 genes. In 61.9% (13/21) of positive cases, an identified cancer predisposition syndrome was linked to the childhoo...
...BRCA2, among others) variants, comparing with an institutional cohort of MMR carriers (n = 35; 2012-2025). We also asses...
...BRCA2), aligning with increased loss of heterozygosity and exon mutational burden. In addition, Alu hypomethylation furt...
...BRCA2, and PALB2, whereas LDLR and TPM1 remained largely unchanged. No consistent correlation was found between the exte...
...BRCA2 (1.3%) and 46.0% of study participants had a PRS in the top quintile of the risk distribution. Univariate analyses...
...BRCA2, BARD1, PALB2, TP53, CHEK2). Lipid-based nanoparticles (LNPs) and polymeric nanoparticles (PNPs) were developed an...
...BRCA2</i> (16.9%), <i>SPEN</i> (16.9%), with 17.1 7.2 (mean standard error of the mean [SEM]) mutation...
...BRCA2 and TP53, which are associated with chemotherapy sensitivity. Olaparib, a PARP inhibitor, provides the greatest cl...
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