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Optimizing treatment and sequencing strategies for maximal survival and net h...

Zhao(M),Li(J),Jiang(Y),Shao(H),Huang(J),Ta... BMC Cancer 2026-03-29

...ALK-positive non-small-cell lung-cancer (NSCLC). METHODS: Related data from phase Ⅱ-Ш clinical trials targeting ALK-posi...

FGFR3-TACC3 fusion as a potential primary resistance mechanism to EGFR-TKI in...

Wang(X),Qiu(L),Liang(J),Liu(F),Ma(X),Yang(... Front Oncol None

...ALK fusion with a mutation allele frequency of 0.19% in circulating tumor DNA (ctDNA), including the known EGFR 19del. P...

Development of PROTACs for targeted degradation of oncogenic TRK fusions.

Kumar(S),Jiang(J),Donald-Paladino(MS),Chen... RSC Chem Biol 2026-04-16

...ALK fusions. TPM3-TRKA degradation by JWJ-01-378 suppressed downstream signaling and reduced cancer cell viability, with...

"WBC-HBP Dissociation" Unveils Occult Xanthogranulomatous Inflammation Mimick...

Zhu(XY),Liu(KC),Zhu(ZB),Zhang(SG) J Hepatocell Carcinoma None

...ALK-, IgG4-) effectively excluding neoplasia and IgG4-related disease. XGI can authentically mimic the hemodynamic signa...

Clinicogenomic Characteristics and Treatment Outcomes of Patients With Advanc...

Miao(EA),Yeap(B),Daher(S),Lomibao(M),Sun(F... JCO Precis Oncol 2026-03-00

...ALK+ NSCLC. Patients with de novo ALK+ squamous and adenosquamous NSCLCs were identified and compared with an ALK+ adeno...

Updates on the Perioperative Management of Resectable Non-Small Cell Lung Can...

Frumm(SM),Florez(N),Lee(JM),Rotow(JK),Chaf... J Natl Compr Canc Netw 2026-03-24

...ALK rearrangements are summarized, and the importance of identifying these patients upfront is emphasized. Throughout, p...

TPM4::ALK Rearranged Cutaneous Epithelioid Vascular Tumor: A Case Report.

Wang(JS),Billings(SD),Ronen(S),McAfee(J),D... J Cutan Pathol 2026-07-00

...ALK fusions have recently been added to this list, in a cohort of five cases. Herein, we report the sixth case (second c...

Baseline vitamin D status and clinical outcomes in advanced non-small cell lu...

Ağdaş(G),Bayir(D),Şahin(E),Cengiz(M),Güven... Sci Rep 2026-04-14

...ALK, ROS1, and other actionable genomic alterations. Baseline serum 25-hydroxyvitamin D levels were measured prior to ni...

Alkaline sphingomyelinase (ENPP7) attenuates DSS-induced colitis by modulatin...

Cao(W),Cheng(Y),Wang(X),Wang(L),Li(R),Pei(... BMC Gastroenterol 2026-04-14

...Alkaline sphingomyelinase (alk-SMase), also known as ectonucleotide pyrophosphatase/phosphodiesterase 7 (ENPP7), is an i...

Real-world trends in diagnosis, treatment, and survival of non-small cell lun...

Pham(VH),Duong(DC),Nguyen(VB),Do(HN),Nguye... BMC Cancer 2026-04-14

...ALK]), and first-line treatment modalities were evaluated. Overall survival (OS) was estimated using the Kaplan-Meier me...

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