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Homologous recombination is the principal pathway for the repair of DNA damag...

Evans(James W),Chernikova(Sophia B),Kachni... Cancer Res 2008-02-19

...XRCC2, XRCC3, Rad51D, BRCA1, or BRCA2 are particularly sensitive to tirapazamine. Consistent with the involvement of hom...

Homologous recombination is necessary for normal lymphocyte development.

Caddle(Lura B),Hasham(Muneer G),Schott(Wil... Mol Cell Biol 2008-05-01

...Xrcc2) HR gene in lymphocyte development. We show that HR is critical for normal B-cell development, with Xrcc2 nullizyg...

Combinational polymorphisms of four DNA repair genes XRCC1, XRCC2, XRCC3, and...

Yen(Ching-Yu),Liu(Shyun-Yeu),Chen(Chung-Ho... J Oral Pathol Med 2008-05-05

...XRCC2 rs2040639-AG, none of these SNPs was found to individually contribute to oral cancer risk. However, for two combin...

XRCC2 and XRCC3 gene polymorphism and risk of pancreatic cancer.

Jiao(Li),Hassan(Manal M),Bondy(Melissa L),... Am J Gastroenterol 2008-04-28

XRCC2 and XRCC3 are key components of the homologous recombination (HR) machinery that repairs DNA double-strand breaks....

Transcriptome analysis of differentiating spermatogonia stimulated with kit l...

Rossi(Pellegrino),Lolicato(Francesca),Grim... Gene Expr Patterns 2008-04-02

...Xrcc2, Mesp1, Phf7, Rtel1), whereas it down-regulates typical spermatogonial markers (for instance: Pole, Ptgs2, Zfpm2, ...

Polymorphism in nucleotide excision repair gene XPC correlates with bleomycin...

Laczmanska(Izabela),Gil(Justyna),Karpinski... Environ Mol Mutagen 2007-12-18

...XRCC2, XRCC3, RAD51, and BRCA1 [homologous recombination], as well as in genes encoding xenobiotic metabolizing enzymes,...

[Cell phenotypes of a mutant in the gene encoding a Rad51 paralog in fission ...

Sultanova(A N),Salakhova(A F),Bashkirov(V ... Genetika 2007-05-09

...Xrcc2, Xrcc3, and Dmcl) indicate the functional diversity and specialization of RecA-like proteins in the line from the ...

Split dose recovery studies using homologous recombination deficient gene kno...

Rao(B S Satish),Tano(Kaori),Takeda(Shunich... J Radiat Res 2007-03-20

...XRCC2, XRCC3, RAD51C and RAD51D were subjected to fractionated irradiation and their survival curves charted. Survival c...

A naturally occurring genetic variant of human XRCC2 (R188H) confers increase...

Danoy(Patrick),Sonoda(Eiichiro),Lathrop(Ma... Biochem Biophys Res Commun 2007-02-12

...XRCC2 (R188H) were more tolerant to cisplatin than those with wild-type XRCC2. Considering that the XRCC2 (R188H) allele...

Role of RAD51C and XRCC3 in genetic recombination and DNA repair.

Liu(Yilun),Tarsounas(Madalena),O'regan(Pau... J Biol Chem 2007-02-27

...XRCC2, and XRCC3) that share homology with RAD51 recombinase and are known as the RAD51 paralogs are important for recom...

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