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"Poisoning" yeast telomeres distinguishes between redundant telomere capping ...

Lamm(Noa),Bsoul(Shhadeh),Kabaha(Majdi M),T... Chromosoma 2013-05-30

...Rad52, while Est1-UMSBP was not. Thus, our results distinguish between two, redundant, telomere capping pathways.

Stress activated protein kinase pathway modulates homologous recombination in...

Bellini(Angela),Girard(Pierre-Marie),Lambe... PLoS One 2013-04-15

...Rad52 phosphorylation and have UVA induced Rad52 foci that persist longer if compared to wild type cells. In addition, s...

Continued DNA synthesis in replication checkpoint mutants leads to fork colla...

Sabatinos(Sarah A),Green(Marc D),Forsburg(... Mol Cell Biol 2013-02-14

...Rad52. Both DNA synthesis and RPA accumulation require the MCM helicase. We propose that a replication fork "collapse po...

Coordinated control of replication and transcription by a SAPK protects genom...

Duch(Alba),Felipe-Abrio(Irene),Barroso(Son... Nature 2013-02-06

...Rad52 foci. In contrast, mrc1(3A) induces Rad53 and survival in the presence of hydroxyurea or methyl methanesulphonate....

MicroRNA-302 replacement therapy sensitizes breast cancer cells to ionizing r...

Liang(Zhongxing),Ahn(Jeffrey),Guo(Donna),V... Pharm Res 2013-08-27

...RAD52, two critical regulators of radioresistance. More promisingly, miR-302a sensitized radioresistant breast cancer ce...

Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BR...

Chun(Jarin),Buechelmaier(Erika S),Powell(S... Mol Cell Biol 2013-02-21

...Rad52. We conclude that human Rad51 paralogs facilitate BRCA2-Rad51-dependent homologous recombination at different stag...

Genetic variation in a hsa-let-7 binding site in RAD52 is associated with bre...

Jiang(Yue),Qin(Zhenzhen),Hu(Zhibin),Guan(X... Carcinogenesis 2013-04-19

...RAD52 showed a consistently reduced breast cancer risk in two stages with a combined odds ratio (OR) of 0.84 [95% confid...

Topoisomerase II- and condensin-dependent breakage of MEC1ATR-sensitive fragi...

Hashash(Nadia),Johnson(Anthony L),Cha(Rita S) PLoS Genet 2013-03-22

...RAD52 epistasis group genes and of TOP3, SGS1, SRS2, MMS4, or MUS81, indicating that homologous recombination and other ...

Influence of common genetic variation on lung cancer risk: meta-analysis of 1...

Timofeeva(Maria N),Hung(Rayjean J),Rafnar(... Hum Mol Genet 2013-03-26

...RAD52 (12p13) have been demonstrated to influence lung cancer risk in candidate- or pathway-based analyses. To identify ...

Replication fork collapse and genome instability in a deoxycytidylate deamina...

Sánchez(Arancha),Sharma(Sushma),Rozenzhak(... Mol Cell Biol 2013-01-14

...Rad52. Moreover, Brc1 suppresses spontaneous mutagenesis in dcd1Δ cells. We propose that replication forks stall and col...

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