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Coordinated control of replication and transcription by a SAPK protects genom...

Duch(Alba),Felipe-Abrio(Irene),Barroso(Son... Nature 2013-02-06

...Rad52 foci. In contrast, mrc1(3A) induces Rad53 and survival in the presence of hydroxyurea or methyl methanesulphonate....

MicroRNA-302 replacement therapy sensitizes breast cancer cells to ionizing r...

Liang(Zhongxing),Ahn(Jeffrey),Guo(Donna),V... Pharm Res 2013-08-27

...RAD52, two critical regulators of radioresistance. More promisingly, miR-302a sensitized radioresistant breast cancer ce...

Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BR...

Chun(Jarin),Buechelmaier(Erika S),Powell(S... Mol Cell Biol 2013-02-21

...Rad52. We conclude that human Rad51 paralogs facilitate BRCA2-Rad51-dependent homologous recombination at different stag...

Topoisomerase II- and condensin-dependent breakage of MEC1ATR-sensitive fragi...

Hashash(Nadia),Johnson(Anthony L),Cha(Rita S) PLoS Genet 2013-03-22

...RAD52 epistasis group genes and of TOP3, SGS1, SRS2, MMS4, or MUS81, indicating that homologous recombination and other ...

Genetic variation in a hsa-let-7 binding site in RAD52 is associated with bre...

Jiang(Yue),Qin(Zhenzhen),Hu(Zhibin),Guan(X... Carcinogenesis 2013-04-19

...RAD52 showed a consistently reduced breast cancer risk in two stages with a combined odds ratio (OR) of 0.84 [95% confid...

RAD52 variants predict platinum resistance and prognosis of cervical cancer.

Shi(Ting-Yan),Yang(Gong),Tu(Xiao-Yu),Yang(... PLoS One 2013-05-22

...RAD52 variants by the SNaPshot assay. We tested in vitro platinum resistance and RAD52 expression by using the MTT and i...

Molecular pathways: understanding the role of Rad52 in homologous recombinati...

Lok(Benjamin H),Powell(Simon N) Clin Cancer Res 2013-05-20

...Rad52 (hRad52), in which yeast Rad52 can promote strand invasion of replication protein A (RPA)-coated single-stranded D...

Stress activated protein kinase pathway modulates homologous recombination in...

Bellini(Angela),Girard(Pierre-Marie),Lambe... PLoS One 2013-04-15

...Rad52 phosphorylation and have UVA induced Rad52 foci that persist longer if compared to wild type cells. In addition, s...

Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-stra...

Limbo(Oliver),Moiani(Davide),Kertokalio(Ar... Nucleic Acids Res 2013-02-22

...Rad52 foci, defective Chk1 signaling and meiotic failure. W248R differs from other ataxia telangiectasia-like disorder a...

"Poisoning" yeast telomeres distinguishes between redundant telomere capping ...

Lamm(Noa),Bsoul(Shhadeh),Kabaha(Majdi M),T... Chromosoma 2013-05-30

...Rad52, while Est1-UMSBP was not. Thus, our results distinguish between two, redundant, telomere capping pathways.

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