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The importance of XRCC2 in RAD51-related DNA damage repair.

Tambini(Cathryn E),Spink(Karen G),Ross(Car... DNA Repair (Amst) 2010-07-27

...XRCC2, appear to help with this process, but their roles are not well understood. Here we show that XRCC2 is highly cons...

DNA ligase IV is a potential molecular target in ACNU sensitivity.

Kondo(Natsuko),Takahashi(Akihisa),Mori(Eii... Cancer Sci 2010-08-18

...XRCC2] and radiation sensitive mutant 54 [Rad54]), and in NHEJ repair (DNA ligase IV [Lig4]). Cellular sensitivity to AC...

Widespread genomic breaks generated by activation-induced cytidine deaminase ...

Hasham(Muneer G),Donghia(Nina M),Coffey(El... Nat Immunol 2010-09-13

...XRCC2 suppressed AID-induced off-target DSBs, promoting B cell survival. Finally, we suggest that aberrations that affec...

Breast cancer risk and common single nucleotide polymorphisms in homologous r...

Silva(Susana N),Tomar(Marta),Paulo(Claudia... Cancer Epidemiol 2010-04-08

...XRCC2 (Ex3+442G>A, R188H, rs3218536), XRCC3 (Ex8-5C>T, T241M, rs861539), NBS1 (Ex5-32C>G, E185Q, rs1805794) and RAD51 5'...

XRCC2 Arg188His polymorphism is not directly associated with breast cancer ri...

Yu(Ke-Da),Chen(Ao-Xiang),Qiu(Li-Xin),Fan(L... Breast Cancer Res Treat 2010-11-09

Several common single-nucleotide polymorphisms (SNPs) within the XRCC2 gene have been identified as potential breast can...

RAD51 paralogs promote homology-directed repair at diversifying immunoglobuli...

Ordinario(Ellen C),Yabuki(Munehisa),Handa(... BMC Mol Biol 2010-02-16

...XRCC2 accelerated the clonal rate of gene conversion, and conversion tracts were significantly longer in RAD51D than XRC...

BRCA1-associated breast and ovarian cancer risks in Poland: no association wi...

Jakubowska(Anna),Gronwald(Jacek),Menkiszak... Breast Cancer Res Treat 2010-02-22

...XRCC2, XRCC3 and Lig4 participate in DNA repair, TP53 in cell cycle check point control, AIB1, AR, COMT, CYP11A1, CYP17A...

Tumor cell kill by c-MYC depletion: role of MYC-regulated genes that control ...

Luoto(Kaisa R),Meng(Alice X),Wasylishen(Am... Cancer Res 2010-12-21

...XRCC2, Rad50, BRCA1, BRCA2, DNA-PKcs, XRCC4, Ku70, and DNA ligase IV. Endogenous MYC protein expression was associated w...

[The association of XRCC2 gene polymorphism with susceptibility to esophageal...

Wang(Na),Dong(Xiu-juan),Li(Yan),Guo(Wei),Z... Zhonghua Yi Xue Yi Chuan Xu... 2009-03-13

...XRCC2 4234G/C did not show significant effect on the risk of developing ESCC and GCA. When the two XRCC2 SNPs were combi...

Genetic polymorphisms in the DNA repair genes XRCC1, XRCC2 and XRCC3 and risk...

Loizidou(Maria A),Michael(Thalia),Neuhause... Breast Cancer Res Treat 2009-02-03

...XRCC2 and XRCC3 and breast cancer in MASTOS, a population-based case-control study of 1,109 Cypriot women with breast ca...

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