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Kinetic analysis of DNA double-strand break repair pathways in Arabidopsis.

Charbonnel(Cyril),Allain(Elisabeth),Galleg... DNA Repair (Amst) 2011-10-18

...xrcc2 xpf mutant can repair DSB, although with severely altered kinetics. This repair leads to massive genetic instabili...

Homologous recombination proteins are associated with centrosomes and are req...

Cappelli(Enrico),Townsend(Stuart),Griffin(... Exp Cell Res 2011-05-31

...XRCC2 protein plays a vital role. Cells deficient in XRCC2 also show disruption of the centrosome, a key component of th...

The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is nec...

Rajesh(Changanamkandath),Baker(Dustin K),P... Nucleic Acids Res 2011-02-09

...XRCC2. Initially discovered as a potential RNA splicing factor, SFPQ was later shown to have homologous recombination an...

Xrcc2 modulates spontaneous and radiation-induced tumorigenesis in Apcmin/+ m...

Haines(Jackie W),Coster(Margaret R),Adam(J... Mol Cancer Res 2011-03-03

...Xrcc2 (7.25 ± 0.50-fold in Apc(min/+) Xrcc2(+/-) mice compared with 2.57 ± 0.35-fold in Apc(min/+) Xrcc2(+/+) mice; t-te...

Structural and functional characterization of the N-terminal domain of human ...

Kim(Young Mee),Choi(Byong-Seok) Int J Biochem Cell Biol 2011-05-18

...XRCC2, but nothing is known about its individual structure or function. In this study, we determined the solution struct...

Polymorphisms in RAD51, XRCC2 and XRCC3 genes of the homologous recombination...

Krupa(Renata),Sliwinski(Tomasz),Wisniewska... Mol Biol Rep 2011-07-26

XRCC2 and XRCC3 proteins are structurally and functionally related to RAD51 which play an important role in the homologo...

Expression of double strand DNA breaks repair genes in pterygium.

Lękawa-Ilczuk(Anna),Antosz(Halina),Rymgaył... Ophthalmic Genet 2011-04-29

...XRCC2, XRCC3, RAD51, RAD51B, RAD51C, RAD51D genes transcripts were detected. Expression of RAD50 protein was analyzed im...

Genetics polymorphism in DNA repair genes by base excision repair pathway (XR...

Romanowicz(Hanna),Smolarz(Beata),Baszczyńs... Pol J Pathol 2011-06-16

...XRCC2-Arg188His and RAD51-135G/C with the breast cancer risk. Genotypes were determined by PCR-RFLP assays in 220 patien...

Genetic variation in radiation and platinum pathways predicts severe acute ra...

Yoon(H H),Catalano(P),Gibson(M K),Skaar(T ... Cancer Chemother Pharmacol 2011-11-22

...XRCC2 5' flanking SNP (detected in 28% of subjects) and of GST-Pi Ile-105-Val (detected in 65% of subjects) were each as...

BRCA1-associated breast and ovarian cancer risks in Poland: no association wi...

Jakubowska(Anna),Gronwald(Jacek),Menkiszak... Breast Cancer Res Treat 2010-02-22

...XRCC2, XRCC3 and Lig4 participate in DNA repair, TP53 in cell cycle check point control, AIB1, AR, COMT, CYP11A1, CYP17A...

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