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Jiang(WenZhi),Yang(Bing),Weeks(Donald P) PLoS One 2015-02-02

...CRISPR/Cas9 system for targeted gene knockout or editing has recently been shown to function in plants in both transient...

Guo(Xue),Yin(Huaqun),Liang(Yili),Hu(Qi),Zh... PLoS One 2015-06-29

...CRISPR/Cas defence systems testifies to its dynamic evolution consistent with the genome heterogeneity. As expected, S. ...

Berezovskaya(Faina S),Wolf(Yuri I),Koonin(... Biol Direct 2015-03-05

...CRISPR-Cas loci revealed by comparative genomics. The results of this analysis might have implications beyond the CRISPR...

Sato(Masahiro),Miyoshi(Kazuchika),Nagao(Yo... Xenotransplantation 2015-01-15

The recent development of the type II clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has...

Liu(Fei),Hu(Yongfei),Wang(Qi),Li(Hong Min)... BMC Genomics 2015-01-30

...CRISPR locus with varied spacers was observed in all 7 clinical isolates, suggesting that they might play an important r...

Lechner(Marcus),Nickel(Astrid I),Wehner(St... BMC Genomics 2015-06-11

...CRISPR systems. Furthermore, we performed a phylogenetic analysis of the Aquificales based on entire genome sequences, a...

Yang(Luhan),Grishin(Dennis),Wang(Gang),Aac... Nat Commun 2015-10-15

...CRISPR/Cas9 and highlights the value of whole-genome sequencing before personalised CRISPR design.

Tay(Melanie),Liu(Su),Yuan(Y Adam) Protein Sci 2015-10-15

...CRISPR)-CRISPR-associated (Cas) defense system is the only adaptive and inheritable immunity found in prokaryotes. The i...

Araki(Motoko),Ishii(Tetsuya) Reprod Biol Endocrinol 2015-03-30

...CRISPR)/Cas, has enabled far more efficient genetic engineering even in non-human primates. This biotechnology is more l...

Chakraborty(Syandan),Ji(HaYeun),Kabadi(Ami... Stem Cell Reports 2015-11-16

...CRISPR/Cas9 system has the potential to enable new approaches to science and medicine, but the technology must be enhanc...