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Metal and RNA binding properties of the hdm2 RING finger domain.

Lai(Z),Freedman(D A),Levine(A J),McLendon(... Biochemistry 1999-01-07

...BRCA1 RING finger peptide. However, there is no similarity in overall tertiary structure, nor is there direct sequence h...

cDNA sequence and chromosomal localization of mouse Dlgh3 gene adjacent to th...

Lin(L),Peters(L L),Ciciotte(S L),Chishti(A H) Biochim Biophys Acta 1999-02-04

...BRCA1 tumor suppressor gene has been mapped. The predicted primary structure of the human MPP3 contains a single copy of...

[Clinical value of gene diagnosis in breast cancer].

Iwase(H) Rinsho Byori 1999-02-19

...BRCA1 and BRCA2 are quite important candidate genes in familial breast cancer. Recently, prophylactic mastectomy has bee...

Marker segregation information in breast/ovarian cancer genetic counseling: i...

Essioux(L),Girodet(C),Sinilnikova(O),Pagès... Am J Med Genet 1999-06-02

...BRCA1 mutation most probably segregated in one and that a mutation other than BRCA1 and BRCA2 was probably involved in t...

In vitro repression of Brca1-associated RING domain gene, Bard1, induces phen...

Irminger-Finger(I),Soriano(J V),Vaudan(G),... J Cell Biol 1999-01-07

...BRCA1. The identification of tumorigenic missense mutations within BRCA1 that impair the formation of BARD1-BRCA1 comple...

Ethics of predictive DNA-testing for hereditary breast and ovarian cancer.

de Wert(G) Patient Educ Couns 1999-11-18

...BRCA1 and -2. Using international guidelines for presymptomatic DNA-testing for Huntington disease and the Li-Fraumeni s...

Structure of an XRCC1 BRCT domain: a new protein-protein interaction module.

Zhang(X),Moréra(S),Bates(P A),Whitehead(P ... EMBO J 1999-01-11

...BRCA1 C-terminus), first identified in the breast cancer suppressor protein BRCA1, is an evolutionarily conserved protei...

BRCA1 and BRCA2 proteins: roles in health and disease.

Duncan(J A),Reeves(J R),Cooke(T G) Mol Pathol 1999-04-29

...BRCA1 and BRCA2. Since the sequencing of these genes, considerable research on the genetics of the mutation carriers has...

Rolling circle amplification of DNA immobilized on solid surfaces and its app...

Hatch(A),Sano(T),Misasi(J),Smith(C L) Genet Anal 1999-05-28

...BRCA1 exon 5. These results demonstrate that RCA offers considerable promise to facilitate effective mutation screening ...

Incidence of loss of heterozygosity at p53 and BRCA1 loci in serous surface c...

Quezado(M M),Moskaluk(C A),Bryant(B),Mills... Hum Pathol 1999-03-02

...BRCA1 gene are uncommon in sporadic ovarian cases. In contrast, germline BRCA1 mutations are responsible for some heredi...

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