样本量：14 物种：Homo sapiens, Homo sapiens 类型：RNA-seq of coding RNA, Cell line - Hi... 2021年4月14日

ALK is driving neuroblastoma (NB) and RET has been shown to be a downstream target of ALK signaling in NB. To get a bett...

样本量：60 物种：Homo sapiens, Homo sapiens 类型：Cell line - High-throughput sequencin... 2020年11月24日

ALK is a tyrosine kinase receptor and oncogene in neuroblastoma (NB). The receptor is activated by the ALKAL2 ligand, bu...

样本量：16 物种：Mus musculus, Mus musculus 类型：Animal - High-throughput sequencing, ... 2020年11月24日

ALK is a tyrosine kinase receptor and oncogene in neuroblastoma (NB). The receptor is activated by the ALKAL2 ligand, bu...

样本量：6 物种：Homo sapiens 类型：RNA-seq of coding RNA 2019年12月22日

...ALK inhibitors occurs. Exploring these mechanisms of resistance, we found that EML4-ALK cells resistant to ALK inhibitor...

样本量：6 物种：Homo sapiens 类型：microRNA profiling by high throughput... 2019年12月15日

...ALK inhibitors occurs. Exploring these mechanisms of resistance, we found that EML4-ALK cells resistant to ALK inhibitor...

样本量：4 物种：Homo sapiens 类型：transcription profiling by array 2019年2月28日

Despite the successful use of drugs targeting the MAPK signaling pathway and immunotherapy in melanoma, the majority of ...

样本量：17 物种：Homo sapiens 类型：RNA-seq of coding RNA 2018年9月1日

Anaplastic Lymphoma Kinase (ALK) is a tyrosine kinase receptor which is a clinical target of major interest in cancer, i...

样本量：16 物种：Homo sapiens 类型：transcription profiling by array 2016年7月3日

...ALK) and multitarget TKIs in terms of cancer cell growth, signaling cascades inhibition, and changes in gene expression ...

样本量：24 物种：Mus musculus 类型：transcription profiling by array 2016年2月28日

...ALK are driver oncogenes both of which are specifically expressed during early neurogenesis. This is in line with the as...

样本量：86 物种：Homo sapiens 类型：comparative genomic hybridization by ... 2016年1月5日

...ALK transgenic mice following Notch1 expression. In support, we show that T cell receptor (TCR) rearrangements are aberr...