Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	ref_context	gc_content	COSMIC_n_overlapping_mutations	ESP_AvgAAsampleReadDepth	ESP_AvgEAsampleReadDepth	ESP_AvgSampleReadDepth	ESP_Chromosome	ESP_Position	ESP_TotalAAsamplesCovered	ESP_TotalEAsamplesCovered	ESP_TotalSamplesCovered	Ensembl_so_accession	Ensembl_so_term	HGNC_AccessionNumbers	HGNC_CCDSIDs	HGNC_Chromosome	HGNC_DateModified	HGNC_DateNameChanged	HGNC_DateSymbolChanged	HGNC_EnsemblGeneID	HGNC_EnsemblIDsuppliedbyEnsembl	HGNC_Genefamilydescription	HGNC_HGNCID	HGNC_LocusGroup	HGNC_LocusType	HGNC_NameSynonyms	HGNC_OMIMIDsuppliedbyNCBI	HGNC_PreviousNames	HGNC_PreviousSymbols	HGNC_PubmedIDs	HGNC_RecordType	HGNC_RefSeqsuppliedbyNCBI	HGNC_Status	HGNC_Synonyms	HGNC_UCSCIDsuppliedbyUCSC	HGNC_UniProtIDsuppliedbyUniProt	HGNC_VEGAIDs	HGVS_coding_DNA_change	HGVS_genomic_change	HGVS_protein_change	UniProt_alt_uniprot_accessions	annotation_transcript	build	ccds_id	dbNSFP_1000Gp1_AC	dbNSFP_1000Gp1_AF	dbNSFP_1000Gp1_AFR_AC	dbNSFP_1000Gp1_AFR_AF	dbNSFP_1000Gp1_AMR_AC	dbNSFP_1000Gp1_AMR_AF	dbNSFP_1000Gp1_ASN_AC	dbNSFP_1000Gp1_ASN_AF	dbNSFP_1000Gp1_EUR_AC	dbNSFP_1000Gp1_EUR_AF	dbNSFP_Ancestral_allele	dbNSFP_CADD_phred	dbNSFP_CADD_raw	dbNSFP_CADD_raw_rankscore	dbNSFP_ESP6500_AA_AF	dbNSFP_ESP6500_EA_AF	dbNSFP_Ensembl_geneid	dbNSFP_Ensembl_transcriptid	dbNSFP_FATHMM_pred	dbNSFP_FATHMM_rankscore	dbNSFP_FATHMM_score	dbNSFP_GERP_NR	dbNSFP_GERP_RS	dbNSFP_GERP_RS_rankscore	dbNSFP_Interpro_domain	dbNSFP_LRT_Omega	dbNSFP_LRT_converted_rankscore	dbNSFP_LRT_pred	dbNSFP_LRT_score	dbNSFP_LR_pred	dbNSFP_LR_rankscore	dbNSFP_LR_score	dbNSFP_MutationAssessor_pred	dbNSFP_MutationAssessor_rankscore	dbNSFP_MutationAssessor_score	dbNSFP_MutationTaster_converted_rankscore	dbNSFP_MutationTaster_pred	dbNSFP_MutationTaster_score	dbNSFP_Polyphen2_HDIV_pred	dbNSFP_Polyphen2_HDIV_rankscore	dbNSFP_Polyphen2_HDIV_score	dbNSFP_Polyphen2_HVAR_pred	dbNSFP_Polyphen2_HVAR_rankscore	dbNSFP_Polyphen2_HVAR_score	dbNSFP_RadialSVM_pred	dbNSFP_RadialSVM_rankscore	dbNSFP_RadialSVM_score	dbNSFP_Reliability_index	dbNSFP_SIFT_converted_rankscore	dbNSFP_SIFT_pred	dbNSFP_SIFT_score	dbNSFP_SLR_test_statistic	dbNSFP_SiPhy_29way_logOdds	dbNSFP_SiPhy_29way_logOdds_rankscore	dbNSFP_SiPhy_29way_pi	dbNSFP_UniSNP_ids	dbNSFP_Uniprot_aapos	dbNSFP_Uniprot_acc	dbNSFP_Uniprot_id	dbNSFP_aaalt	dbNSFP_aapos	dbNSFP_aapos_FATHMM	dbNSFP_aapos_SIFT	dbNSFP_aaref	dbNSFP_cds_strand	dbNSFP_codonpos	dbNSFP_folddegenerate	dbNSFP_genename	dbNSFP_hg18_pos1coor	dbNSFP_phastCons100way_vertebrate	dbNSFP_phastCons100way_vertebrate_rankscore	dbNSFP_phastCons46way_placental	dbNSFP_phastCons46way_placental_rankscore	dbNSFP_phastCons46way_primate	dbNSFP_phastCons46way_primate_rankscore	dbNSFP_phyloP100way_vertebrate	dbNSFP_phyloP100way_vertebrate_rankscore	dbNSFP_phyloP46way_placental	dbNSFP_phyloP46way_placental_rankscore	dbNSFP_phyloP46way_primate	dbNSFP_phyloP46way_primate_rankscore	dbNSFP_refcodon	gencode_transcript_name	gencode_transcript_status	gencode_transcript_tags	gencode_transcript_type	gene_type	havana_transcript	init_n_lod	init_t_lod	isArtifactMode	n_alt_count	n_ref_count	oxoGCut	pox	pox_cutoff	qox	refseq_mrna_id	t_alt_count	t_lod_fstar	t_ref_count	tumor_f
ZMYM3	9203	ucsc.edu	hg19	X	70468373	70468373	+	Missense_Mutation	SNP	C	C	T			TCGA-V4-A9F2-01A-11D-A39W-08	TCGA-V4-A9F2-10A-01D-A39Z-08	C	C					Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina HiSeq	c48e6101-f6ab-4e1f-ad0a-adc6ebaa340b	8f068522-7afa-46ae-9055-37e0656dacdb																										AGGGCTTGTGCGCTGGAGGGA	0.607	0	32.0	30.0	31.0	X	70468373	2203	4300	6503	SO:0001630	splice_region_variant	AB002383	CCDS14409.1, CCDS55443.1, CCDS55444.1	Xq13.1	2013-01-08	2005-12-19	2005-12-19	ENSG00000147130	ENSG00000147130	"""Zinc fingers, MYM type"""	13054	protein-coding gene	gene with protein product		300061	"""zinc finger protein 261"""	ZNF261	10486218	Standard	NM_201599	Approved	ZNF198L2, DXS6673E, KIAA0385, MYM	uc004dzh.2	Q14202	OTTHUMG00000021799	ENST00000353904.2:c.1738-1G>A	X.37:g.70468373C>T		D3DVV3|O15089|Q96E26	ENST00000353904.2	37	CCDS14409.1	.	.	.	.	.	.	.	.	.	.	c	1.777	-0.482793	0.04383	0.0	1.49E-4	ENSG00000147130	ENST00000314425;ENST00000373998;ENST00000353904;ENST00000373984;ENST00000373988	T;T;T;T;T	0.43688	1.52;0.94;1.52;1.52;1.52	5.27	3.35	0.38373	TRASH (1);	0.356856	0.23779	N	0.044656	T	0.22399	0.0540	N	0.12182	0.205	0.21147	N	0.999775	B;B	0.19706	0.038;0.022	B;B	0.13407	0.009;0.004	T	0.13575	-1.0504	10	0.30854	T	0.27	-6.7912	8.5121	0.33224	0.1527:0.7642:0.0:0.0832	.	580;580	Q14202-2;Q14202	.;ZMYM3_HUMAN	H	580;580;580;582;582	ENSP00000322845:R580H;ENSP00000363110:R580H;ENSP00000343909:R580H;ENSP00000363096:R582H;ENSP00000363100:R582H	ENSP00000322845:R580H	R	-	2	0	ZMYM3	70385098	0.072000	0.21174	1.000000	0.80357	0.488000	0.33401	0.125000	0.15749	0.990000	0.38787	0.183000	0.17082	CGC	ZMYM3-201	KNOWN	basic|appris_candidate|CCDS	protein_coding	protein_coding	OTTHUMT00000057154.1				3	26					NM_201599	4		11	
MRPS35	60488	broad.mit.edu	hg19	12	27863872	27863872	+	Silent	SNP	C	C	T			TCGA-V4-A9F2-01A-11D-A39W-08	TCGA-V4-A9F2-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c48e6101-f6ab-4e1f-ad0a-adc6ebaa340b	8f068522-7afa-46ae-9055-37e0656dacdb	g.chr12:27863872C>T	ENST00000081029.3	+	1	167	c.96C>T	c.(94-96)gtC>gtT	p.V32V	MRPS35_ENST00000538315.1_Silent_p.V32V	NM_021821.3	NP_068593.2	P82673	RT35_HUMAN	mitochondrial ribosomal protein S35	32		DNA damage response, detection of DNA damage	mitochondrial small ribosomal subunit		breast(1)|endometrium(1)|kidney(1)|lung(2)|urinary_tract(1)	6	Lung SC(9;0.0873)				CCACTCCGGTCCCGACACCTA	0.652	0	59.0	47.0	51.0	12	27863872	2203	4300	6503	SO:0001819	synonymous_variant	AF182422	CCDS8714.1, CCDS53769.1	12p11	2012-09-13			ENSG00000061794	ENSG00000061794	"""Mitochondrial ribosomal proteins / small subunits"""	16635	protein-coding gene	gene with protein product		611995			11279123	Standard	NM_021821	Approved	MRPS28, MDS023	uc001rih.3	P82673	OTTHUMG00000169215	ENST00000081029.3:c.96C>T	12.37:g.27863872C>T		B2RDZ7|Q96Q21	ENST00000081029.3	37	CCDS8714.1																																																																																			MRPS35-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000402897.1		14.774251	0	-7	21	0	0	1	0	NM_021821	5	14.774251	5	0.500000
GNAQ	2776	broad.mit.edu	hg19	9	80409488	80409488	+	Missense_Mutation	SNP	T	T	A	rs121913492		TCGA-V4-A9F2-01A-11D-A39W-08	TCGA-V4-A9F2-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c48e6101-f6ab-4e1f-ad0a-adc6ebaa340b	8f068522-7afa-46ae-9055-37e0656dacdb	g.chr9:80409488T>A	ENST00000286548.4	-	5	848	c.626A>T	c.(625-627)cAa>cTa	p.Q209L	GNAQ_ENST00000397476.3_Missense_Mutation_p.Q7L	NM_002072.3	NP_002063.2	P50148	GNAQ_HUMAN	guanine nucleotide binding protein (G protein), q polypeptide	209		activation of adenylate cyclase activity by G-protein signaling pathway|activation of phospholipase C activity by dopamine receptor signaling pathway|glutamate signaling pathway|negative regulation of protein kinase activity|platelet activation|protein ADP-ribosylation|protein stabilization|regulation of action potential|regulation of catenin import into nucleus	cytoplasm|heterotrimeric G-protein complex	G-protein beta/gamma-subunit complex binding|G-protein-coupled receptor binding|GTP binding|GTPase activator activity|GTPase activity|signal transducer activity	NS(1)|endometrium(3)|eye(229)|kidney(1)|large_intestine(4)|lung(6)|meninges(11)|ovary(1)|prostate(1)|skin(44)|upper_aerodigestive_tract(1)	302					CTCTGACCTTTGGCCCCCTAC	0.348	153	108.0	105.0	106.0	9	80409488	2203	4300	6503	SO:0001583	missense		CCDS6658.1	9q21	2010-03-17			ENSG00000156052	ENSG00000156052		4390	protein-coding gene	gene with protein product		600998			8825633	Standard	NM_002072	Approved	G-ALPHA-q, GAQ	uc004akw.3	P50148	OTTHUMG00000020059	ENST00000286548.4:c.626A>T	9.37:g.80409488T>A	ENSP00000286548:p.Gln209Leu	O15108|Q13462|Q6NT27|Q92471|Q9BZB9	ENST00000286548.4	37	CCDS6658.1	.	.	.	.	.	.	.	.	.	.	T	29.2	4.985495	0.93044	.	.	ENSG00000156052	ENST00000286548;ENST00000397476	D;D	0.91237	-2.81;-2.81	5.69	5.69	0.88448	.	0.000000	0.85682	D	0.000000	D	0.97573	0.9205	H	0.99347	4.525	0.80722	D	1	D	0.89917	1.0	D	0.87578	0.998	D	0.99402	1.0928	10	0.87932	D	0	.	15.9502	0.79827	0.0:0.0:0.0:1.0	.	209	P50148	GNAQ_HUMAN	L	209;7	ENSP00000286548:Q209L;ENSP00000443197:Q7L	ENSP00000286548:Q209L	Q	-	2	0	GNAQ	79599308	1.000000	0.71417	0.999000	0.59377	0.995000	0.86356	8.040000	0.89188	2.167000	0.68274	0.460000	0.39030	CAA	GNAQ-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000052761.1		60.121832	0	-22	90	0	0	1	0	NM_002072	19	60.169552	22	0.463415
NEBL	10529	ucsc.edu	hg19	10	21102943	21102943	+	Missense_Mutation	SNP	C	C	A			TCGA-V4-A9F2-01A-11D-A39W-08	TCGA-V4-A9F2-10A-01D-A39Z-08	C	C					Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina HiSeq	c48e6101-f6ab-4e1f-ad0a-adc6ebaa340b	8f068522-7afa-46ae-9055-37e0656dacdb																										GTCTACCTTTCATCTGTTTAT	0.333	1	177.0	164.0	168.0	10	21102943	2203	4300	6503	SO:0001583	missense	Y16241	CCDS7133.1, CCDS7134.1	10p12	2014-09-17			ENSG00000078114	ENSG00000078114		16932	protein-coding gene	gene with protein product		605491			9733644, 10470015	Standard	NM_213569	Approved		uc001iqi.3	O76041	OTTHUMG00000017788	ENST00000377122.4:c.2271G>T	10.37:g.21102943C>A	ENSP00000366326:p.Met757Ile	B0YJ45|Q2TBD0|Q70I54|Q9UIC4	ENST00000377122.4	37	CCDS7134.1	.	.	.	.	.	.	.	.	.	.	C	11.38	1.621180	0.28889	.	.	ENSG00000078114	ENST00000377122	T	0.46819	0.86	6.01	5.11	0.69529	.	0.284283	0.38005	N	0.001848	T	0.37999	0.1024	L	0.34521	1.04	0.80722	D	1	B	0.15141	0.012	B	0.24006	0.05	T	0.15809	-1.0424	10	0.14656	T	0.56	.	15.0403	0.71785	0.0:0.9324:0.0:0.0676	.	757	O76041	NEBL_HUMAN	I	757	ENSP00000366326:M757I	ENSP00000366326:M757I	M	-	3	0	NEBL	21142949	1.000000	0.71417	1.000000	0.80357	0.994000	0.84299	2.686000	0.46968	1.558000	0.49541	0.650000	0.86243	ATG	NEBL-004	KNOWN	basic|CCDS	protein_coding	protein_coding	OTTHUMT00000047113.1				0	61					NM_006393	4		28	
KRR1	11103	broad.mit.edu	hg19	12	75897718	75897718	+	Missense_Mutation	SNP	T	T	C			TCGA-V4-A9F2-01A-11D-A39W-08	TCGA-V4-A9F2-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c48e6101-f6ab-4e1f-ad0a-adc6ebaa340b	8f068522-7afa-46ae-9055-37e0656dacdb	g.chr12:75897718T>C	ENST00000229214.4	-	7	820	c.797A>G	c.(796-798)tAt>tGt	p.Y266C	KRR1_ENST00000438169.2_Intron	NM_007043.6	NP_008974.5	Q13601	KRR1_HUMAN	KRR1, small subunit (SSU) processome component, homolog (yeast)	266	Lys-rich.	rRNA processing	nucleolus|ribonucleoprotein complex	RNA binding	breast(1)|central_nervous_system(1)|endometrium(1)|large_intestine(3)|liver(1)|lung(1)|ovary(1)|pancreas(1)|urinary_tract(1)	11					GAATGGCGTATATTCTTTCTT	0.343	0	259.0	245.0	250.0	12	75897718	2203	4300	6503	SO:0001583	missense	U55766	CCDS9012.1	12q	2011-03-15	2006-05-18	2006-05-18	ENSG00000111615	ENSG00000111615		5176	protein-coding gene	gene with protein product		612817	"""HIV-1 rev binding protein 2"", ""HIV-1 Rev binding protein 2"""	HRB2	7505766, 11027267, 11359931, 8675026	Standard	NM_007043	Approved	RIP-1	uc001sxt.3	Q13601	OTTHUMG00000169759	ENST00000229214.4:c.797A>G	12.37:g.75897718T>C	ENSP00000229214:p.Tyr266Cys	A0FIK6|A0JLP0|B2R989|E7EUQ0|Q8NEA8|Q8TC37|Q96AT5	ENST00000229214.4	37	CCDS9012.1	.	.	.	.	.	.	.	.	.	.	T	23.0	4.368063	0.82463	.	.	ENSG00000111615	ENST00000229214	T	0.31510	1.49	5.73	5.73	0.89815	.	0.000000	0.85682	D	0.000000	T	0.65821	0.2728	M	0.92738	3.34	0.80722	D	1	D	0.89917	1.0	D	0.91635	0.999	T	0.75340	-0.3352	10	0.87932	D	0	-8.1063	16.0153	0.80434	0.0:0.0:0.0:1.0	.	266	Q13601	KRR1_HUMAN	C	266	ENSP00000229214:Y266C	ENSP00000229214:Y266C	Y	-	2	0	KRR1	74183985	1.000000	0.71417	0.997000	0.53966	0.954000	0.61252	7.324000	0.79115	2.190000	0.69967	0.397000	0.26171	TAT	KRR1-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000405727.1		-7.701973	0	-30	165	0	0	1	0	NM_007043	5	11.829324	88	0.053763
TMEM8B	51754	broad.mit.edu	hg19	9	35846950	35846950	+	Silent	SNP	G	G	A			TCGA-V4-A9F2-01A-11D-A39W-08	TCGA-V4-A9F2-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c48e6101-f6ab-4e1f-ad0a-adc6ebaa340b	8f068522-7afa-46ae-9055-37e0656dacdb	g.chr9:35846950G>A	ENST00000377988.2	+	10	2065	c.777G>A	c.(775-777)gtG>gtA	p.V259V	TMEM8B_ENST00000377991.4_Silent_p.V259V|TMEM8B_ENST00000377996.1_Silent_p.V259V|TMEM8B_ENST00000439587.2_Silent_p.V259V	NM_001042590.2	NP_001036055.1	A6NDV4	TMM8B_HUMAN	transmembrane protein 8B	259		cell-matrix adhesion|regulation of growth|regulation of mitotic cell cycle	cell surface|endoplasmic reticulum|integral to membrane|mitochondrion|nucleus|plasma membrane	protein binding	breast(1)|endometrium(2)|large_intestine(2)|lung(1)|ovary(1)	7					GTCGATATGTGCTGGAAGCTG	0.552	0	212.0	160.0	177.0	9	35846950	2203	4300	6503	SO:0001819	synonymous_variant	BC043384	CCDS6595.1, CCDS43800.1	9p13.3	2009-06-12	2009-06-12	2009-06-12	ENSG00000137103	ENSG00000137103		21427	protein-coding gene	gene with protein product	"""nasopharyngeal carcinoma expressed 6"""		"""chromosome 9 open reading frame 127"""	C9orf127	12918109, 8619474	Standard	NM_016446	Approved	NAG-5, NGX6	uc003zym.4	A6NDV4	OTTHUMG00000019885	ENST00000377991.4:c.777G>A	9.37:g.35846950G>A		B3KQF3|O75539|Q49AB1|Q4KMX5|Q5TCW5|Q9HBY2|Q9P0U7	ENST00000377991.4	37	CCDS43800.1																																																																																			TMEM8B-005	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000052388.2		2.837767	0	12	89	0	0	1	0	NM_016446	5	11.085731	46	0.098039
ITPKB	3707	broad.mit.edu	hg19	1	226923298	226923298	+	Missense_Mutation	SNP	C	C	G			TCGA-V4-A9F2-01A-11D-A39W-08	TCGA-V4-A9F2-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c48e6101-f6ab-4e1f-ad0a-adc6ebaa340b	8f068522-7afa-46ae-9055-37e0656dacdb	g.chr1:226923298C>G	ENST00000429204.1	-	2	2189	c.1862G>C	c.(1861-1863)aGt>aCt	p.S621T	ITPKB_ENST00000366784.1_Missense_Mutation_p.S621T|ITPKB_ENST00000272117.3_Missense_Mutation_p.S621T	NM_002221.3	NP_002212.3	P27987	IP3KB_HUMAN	inositol-trisphosphate 3-kinase B	621				ATP binding|calmodulin binding|inositol trisphosphate 3-kinase activity	central_nervous_system(1)|endometrium(2)|kidney(4)|large_intestine(4)|lung(13)|ovary(4)|prostate(1)|skin(1)	30		Prostate(94;0.0773)			CTCAGGGTCACTGGAGATGTC	0.587	0	123.0	114.0	117.0	1	226923298	2203	4300	6503	SO:0001583	missense	AJ242780	CCDS1555.1	1q42.12	2011-04-28	2011-04-28		ENSG00000143772	ENSG00000143772		6179	protein-coding gene	gene with protein product		147522	"""inositol 1,4,5-trisphosphate 3-kinase B"""		1654894, 1330886	Standard	NM_002221	Approved	IP3KB, IP3-3KB	uc010pvo.2	P27987	OTTHUMG00000037582	ENST00000272117.3:c.1862G>C	1.37:g.226923298C>G	ENSP00000272117:p.Ser621Thr	Q5VWL9|Q5VWM0|Q96BZ2|Q96JS1|Q9UH47	ENST00000272117.3	37	CCDS1555.1	.	.	.	.	.	.	.	.	.	.	C	29.7	5.029051	0.93518	.	.	ENSG00000143772	ENST00000272117;ENST00000429204;ENST00000366784	T;T;T	0.53206	1.29;1.29;0.63	5.68	5.68	0.88126	.	0.000000	0.85682	D	0.000000	T	0.58878	0.2153	L	0.27053	0.805	0.51482	D	0.999926	D	0.76494	0.999	D	0.80764	0.994	T	0.56786	-0.7921	10	0.44086	T	0.13	-13.9239	20.14	0.98056	0.0:1.0:0.0:0.0	.	621	P27987	IP3KB_HUMAN	T	621	ENSP00000272117:S621T;ENSP00000411152:S621T;ENSP00000355748:S621T	ENSP00000272117:S621T	S	-	2	0	ITPKB	224989921	1.000000	0.71417	1.000000	0.80357	0.997000	0.91878	6.487000	0.73633	2.837000	0.97791	0.591000	0.81541	AGT	ITPKB-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000091632.1		159.835767	0	10	129	0	0	1	0	NM_002221	47	160.153296	36	0.566265
ARHGEF17	9828	broad.mit.edu	hg19	11	73021064	73021064	+	Missense_Mutation	SNP	T	T	G			TCGA-V4-A9F2-01A-11D-A39W-08	TCGA-V4-A9F2-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c48e6101-f6ab-4e1f-ad0a-adc6ebaa340b	8f068522-7afa-46ae-9055-37e0656dacdb	g.chr11:73021064T>G	ENST00000263674.3	+	1	1731	c.1381T>G	c.(1381-1383)Tcc>Gcc	p.S461A		NM_014786.3	NP_055601.2	Q96PE2	ARHGH_HUMAN	Rho guanine nucleotide exchange factor (GEF) 17	461		actin cytoskeleton organization|apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol	Rho guanyl-nucleotide exchange factor activity	endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(7)|lung(15)|ovary(2)|skin(2)	32					ACAGCGGAAGTCCCTGTCAAA	0.577	0	74.0	79.0	77.0	11	73021064	2200	4293	6493	SO:0001583	missense	AF378754	CCDS8221.1	11q13.3	2011-11-16			ENSG00000110237	ENSG00000110237	"""Rho guanine nucleotide exchange factors"""	21726	protein-coding gene	gene with protein product	"""Rho-specific guanine-nucleotide exchange factor 164 kDa"", ""tumor endothelial marker 4"""				11559528, 12071859	Standard	NM_014786	Approved	TEM4, KIAA0337, p164-RhoGEF	uc001otu.3	Q96PE2	OTTHUMG00000167971	ENST00000263674.3:c.1381T>G	11.37:g.73021064T>G	ENSP00000263674:p.Ser461Ala	B2RP20|Q86XU2|Q8N2S0|Q9Y4G3	ENST00000263674.3	37	CCDS8221.1	.	.	.	.	.	.	.	.	.	.	T	20.9	4.058516	0.76074	.	.	ENSG00000110237	ENST00000263674	T	0.71341	-0.56	5.01	5.01	0.66863	.	0.186430	0.34435	N	0.003965	T	0.75517	0.3860	L	0.29908	0.895	0.38199	D	0.940129	D	0.64830	0.994	D	0.72625	0.978	T	0.80578	-0.1320	10	0.87932	D	0	-16.1841	13.5607	0.61788	0.0:0.0:0.0:1.0	.	461	Q96PE2	ARHGH_HUMAN	A	461	ENSP00000263674:S461A	ENSP00000263674:S461A	S	+	1	0	ARHGEF17	72698712	1.000000	0.71417	0.989000	0.46669	0.559000	0.35586	7.847000	0.86896	1.876000	0.54355	0.379000	0.24179	TCC	ARHGEF17-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000397365.1		17.611395	0	4	42	0	0	1	0	NM_014786	7	19.380225	22	0.241379
RSG1	79363	ucsc.edu	hg19	1	16559053	16559053	+	Missense_Mutation	SNP	C	C	T	rs142028968	byFrequency	TCGA-V4-A9F2-01A-11D-A39W-08	TCGA-V4-A9F2-10A-01D-A39Z-08	C	C					Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina HiSeq	c48e6101-f6ab-4e1f-ad0a-adc6ebaa340b	8f068522-7afa-46ae-9055-37e0656dacdb																										ACCTGCTATGCGGGCCAGCTG	0.587	2	64.0	62.0	63.0	1	16559053	2203	4300	6503	SO:0001583	missense	BC008702	CCDS171.1	1p36.13	2014-02-21	2011-02-22	2011-02-22	ENSG00000132881	ENSG00000132881		28127	protein-coding gene	gene with protein product	"""Rem/Rab-Similar GTPase 1"""		"""chromosome 1 open reading frame 89"""	C1orf89	19767740	Standard	NM_030907	Approved	MGC10731	uc001ayd.3	Q9BU20	OTTHUMG00000002214	ENST00000375599.3:c.479G>A	1.37:g.16559053C>T	ENSP00000364749:p.Arg160His	Q5TEV7	ENST00000375599.3	37	CCDS171.1	.|.	.|.	.|.	.|.	.|.	.|.	.|.	.|.	.|.	.|.	C|C	18.91|18.91	3.722860|3.722860	0.68959|0.68959	6.81E-4|6.81E-4	1.16E-4|1.16E-4	ENSG00000132881|ENSG00000132881	ENST00000434014|ENST00000375599	.|T	.|0.69040	.|-0.37	5.61|5.61	5.61|5.61	0.85477|0.85477	.|Mitochondrial Rho-like (1);	.|0.064449	.|0.64402	.|D	.|0.000007	T|T	0.80401|0.80401	0.4616|0.4616	M|M	0.71206|0.71206	2.165|2.165	0.53688|0.53688	D|D	0.999973|0.999973	.|D	.|0.89917	.|1.0	.|D	.|0.65773	.|0.938	T|T	0.81351|0.81351	-0.0972|-0.0972	5|10	.|0.59425	.|D	.|0.04	-4.6237|-4.6237	17.126|17.126	0.86714|0.86714	0.0:1.0:0.0:0.0|0.0:1.0:0.0:0.0	.|.	.|160	.|Q9BU20	.|RSG1_HUMAN	T|H	91|160	.|ENSP00000364749:R160H	.|ENSP00000364749:R160H	A|R	-|-	1|2	0|0	RSG1|RSG1	16431640|16431640	0.995000|0.995000	0.38212|0.38212	0.845000|0.845000	0.33349|0.33349	0.478000|0.478000	0.33099|0.33099	3.342000|3.342000	0.52159|0.52159	2.652000|2.652000	0.90054|0.90054	0.655000|0.655000	0.94253|0.94253	GCA|CGC	RSG1-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000006279.2				-11	54					NM_030907	4		33	
AC015922.5	0	broad.mit.edu	hg19	17	15736892	15736892	+	RNA	DEL	A	A	-			TCGA-V4-A9F2-01A-11D-A39W-08	TCGA-V4-A9F2-10A-01D-A39Z-08							Unknown	Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c48e6101-f6ab-4e1f-ad0a-adc6ebaa340b	8f068522-7afa-46ae-9055-37e0656dacdb	g.chr17:15736892delA	ENST00000584636.1	+	0	316																					CAACTCTTCCAAGGCCTGTCT	0.453	0																																				17.37:g.15736892delA			ENST00000584636.1	37																																																																																				AC015922.5-002	KNOWN	basic	processed_transcript	pseudogene	OTTHUMT00000444654.1	.	.		1	15						2		4	0.33