Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	rsID	rsID_ref_var_alleles	CAF	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumor_var_reads	tumor_vaf	normal_ref_reads_val	normal_var_reads_val	normal_vaf_val	tumor_ref_reads_val	tumor_var_reads_val	tumor_vaf_val
CA5B	0	genome.wustl.edu	37	X	15790686	15790686	+	Missense_Mutation	SNP	C	C	G			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	X	15790686	15790686	C	G	SNP	CA5B	ENST00000318636	human	ensembl	74_37	1	known	missense	c.408	p.I136M	0.02	pfam_Carbonic_anhydrase_a,superfamily_Carbonic_anhydrase_a,pfscan_Carbonic_anhydrase_a	pfam_Carbonic_anhydrase_a,superfamily_Carbonic_anhydrase_a,pfscan_Carbonic_anhydrase_a	0	no_errors	0	0	0	30	0	0	5	15	75	117	0	0.00	22	96	81.36
MTMR8	0	genome.wustl.edu	37	X	63488809	63488809	+	Missense_Mutation	SNP	T	T	G			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	X	63488809	63488809	T	G	SNP	MTMR8	ENST00000374852	human	ensembl	74_37	-1	known	missense	c.1723	p.I575L	0.229	NULL	pfam_Myotubularin-like_Pase_dom,smart_Tyr_Pase_cat	0	no_errors	0	0	0	26	0	0	1	8	88.89	103	0	0.00	27	21	43.75
VWA5B1	0	genome.wustl.edu	37	1	20640980	20640980	+	Missense_Mutation	SNP	C	C	T			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	1	20640980	20640980	C	T	SNP	VWA5B1	ENST00000289815	human	ensembl	74_37	1	known	missense	c.458	p.T153M	0.993	NULL	pfam_VWF_A,smart_VWF_A,pfscan_VWF_A	0	no_errors	rs374632705	C->T	0	63	0	0	27	17	38.64	126	0	0.00	75	45	37.50
CLASP1	0	genome.wustl.edu	37	2	122165068	122165068	+	Missense_Mutation	SNP	A	A	G			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	2	122165068	122165068	A	G	SNP	CLASP1	ENST00000263710	human	ensembl	74_37	-1	known	missense	c.2648	p.L883P	1	superfamily_ARM-type_fold	pfam_CLASP_N_dom,pfam_HEAT,superfamily_ARM-type_fold,pfscan_HEAT_type_2	0	no_errors	0	0	0	57	0	0	37	21	36.21	165	0	0.00	165	96	36.78
NR1I2	0	genome.wustl.edu	37	3	119534625	119534625	+	Silent	SNP	C	C	T			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	3	119534625	119534625	C	T	SNP	NR1I2	ENST00000337940	human	ensembl	74_37	1	known	silent	c.1224	p.F408	0	pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core	pfam_Nucl_hrmn_rcpt_lig-bd_core,pfam_Znf_hrmn_rcpt,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt,pfscan_Znf_hrmn_rcpt	0	no_errors	rs369188703	C->T	0	39	0	0	16	8	33.33	119	0	0.00	80	55	40.44
PEX5L	0	genome.wustl.edu	37	3	179519473	179519473	+	RNA	SNP	A	A	C			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	3	179519473	179519473	A	C	SNP	PEX5L	ENST00000467440	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002	0	0	0	no_errors	0	0	0	81	0	0	53	37	41.11	183	0	0.00	145	85	36.96
ADAM29	0	genome.wustl.edu	37	4	175897904	175897904	+	Nonsense_Mutation	SNP	G	G	T			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	4	175897904	175897904	G	T	SNP	ADAM29	ENST00000359240	human	ensembl	74_37	1	known	nonsense	c.1228	p.E410*	0.053	pfam_Blood-coag_inhib_Disintegrin,superfamily_Blood-coag_inhib_Disintegrin,smart_Blood-coag_inhib_Disintegrin,pfscan_Blood-coag_inhib_Disintegrin	pfam_Peptidase_M12B,pfam_ADAM_Cys-rich,pfam_Peptidase_M12B_N,pfam_Blood-coag_inhib_Disintegrin,superfamily_Blood-coag_inhib_Disintegrin,smart_Blood-coag_inhib_Disintegrin,smart_ADAM_Cys-rich,pfscan_Blood-coag_inhib_Disintegrin,pfscan_Peptidase_M12B,prints_Blood-coag_inhib_Disintegrin	0	no_errors	0	0	0	40	1	2.38	23	29	55.77	134	0	0.00	122	99	44.80
MCC	0	genome.wustl.edu	37	5	112384918	112384918	+	Missense_Mutation	SNP	G	G	A			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	5	112384918	112384918	G	A	SNP	MCC	ENST00000302475	human	ensembl	74_37	-1	known	missense	c.1957	p.R653W	1	NULL	pfam_USH1C-bd_PDZ_domain,superfamily_tRNA-bd_arm	0	no_errors	rs139015770	G->A	0	43	0	0	25	6	19.35	88	0	0.00	86	4	4.44
SCAF8	0	genome.wustl.edu	37	6	155153402	155153402	+	Missense_Mutation	SNP	C	C	G			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	6	155153402	155153402	C	G	SNP	SCAF8	ENST00000367186	human	ensembl	74_37	1	known	missense	c.2887	p.L963V	0.996	NULL	pfam_RNA_pol_II-bd,pfam_RRM_dom,superfamily_ENTH_VHS,smart_CID_dom,smart_RRM_dom,pfscan_RRM_dom	0	no_errors	0	0	0	49	0	0	27	23	46	184	0	0.00	157	130	45.14
GTF2I	0	genome.wustl.edu	37	7	74146970	74146970	+	Missense_Mutation	SNP	T	T	A			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	7	74146970	74146970	T	A	SNP	GTF2I	ENST00000324896	human	ensembl	74_37	1	known	missense	c.1271	p.L424H	1	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	0	no_errors	0	0	0	346	0	0	206	136	39.65	62	0	0.00	69	55	44.35
SEC61A2	0	genome.wustl.edu	37	10	12211342	12211342	+	RNA	SNP	G	G	A			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	10	12211342	12211342	G	A	SNP	SEC61A2	ENST00000495368	human	ensembl	74_37	1	known	rna	NULL	NULL	0	0	0	0	no_errors	rs376483075	G->A	0	38	0	0	26	11	29.73	229	0	0.00	182	128	41.29
OR5M9	0	genome.wustl.edu	37	11	56230566	56230566	+	Silent	SNP	G	G	A			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	11	56230566	56230566	G	A	SNP	OR5M9	ENST00000279791	human	ensembl	74_37	-1	known	silent	c.312	p.A104	0	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	0	no_errors	0	0	0	21	0	0	10	8	44.44	153	0	0.00	102	76	42.46
CTSC	0	genome.wustl.edu	37	11	88027335	88027335	+	Missense_Mutation	SNP	C	C	T			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	11	88027335	88027335	C	T	SNP	CTSC	ENST00000227266	human	ensembl	74_37	-1	known	missense	c.1231	p.G411S	1	pfam_Peptidase_C1A_C,smart_Peptidase_C1A_C,prints_Peptidase_C1A_C	pfam_Peptidase_C1A_C,pfam_CathepsinC_exc,smart_Peptidase_C1A_C,prints_Peptidase_C1A_C	0	no_errors	0	0	0	42	0	0	22	17	43.59	110	0	0.00	86	43	33.33
COL4A1	0	genome.wustl.edu	37	13	110822103	110822103	+	Missense_Mutation	SNP	G	G	A			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	13	110822103	110822103	G	A	SNP	COL4A1	ENST00000375820	human	ensembl	74_37	-1	known	missense	c.3749	p.P1250L	1	NULL	pfam_Collagen,pfam_Collagen_VI_NC,superfamily_C-type_lectin_fold,smart_Collagen_VI_NC	0	no_errors	0	0	0	72	0	0	61	9	12.86	167	0	0.00	170	14	7.57
GYS1	0	genome.wustl.edu	37	19	49477938	49477938	+	Missense_Mutation	SNP	T	T	C			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	19	49477938	49477938	T	C	SNP	GYS1	ENST00000323798	human	ensembl	74_37	-1	known	missense	c.1361	p.D454G	1	pfam_Glycogen_synth	pfam_Glycogen_synth,pfam_Glyco_trans_1,pfam_Starch_synth_cat_dom	0	no_errors	0	0	0	54	0	0	38	10	20.83	81	0	0.00	62	27	30.34
PLXNB2	0	genome.wustl.edu	37	22	50721178	50721178	+	Silent	SNP	G	G	C			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	22	50721178	50721178	G	C	SNP	PLXNB2	ENST00000359337	human	ensembl	74_37	-1	known	silent	c.2949	p.P983	0	pfam_IPT,superfamily_Ig_E-set,smart_IPT	pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_IPT,pfam_Semap_dom,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,pfscan_Semap_dom	0	no_errors	0	0	0	169	0	0	78	47	37.6	117	0	0.00	75	46	38.02
MTMR8	0	genome.wustl.edu	37	X	63488791	63488806	+	Frame_Shift_Del	DEL	TATTCAGGTCTCCATT	TATTCAGGTCTCCATT	-			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	TATTCAGGTCTCCATT	TATTCAGGTCTCCATT	TATTCAGGTCTCCATT	-	TATTCAGGTCTCCATT	TATTCAGGTCTCCATT	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	X	63488791	63488806	TATTCAGGTCTCCATT	0	DEL	MTMR8	ENST00000374852	human	ensembl	74_37	-1	known	frame_shift_del	c.1741_1726	p.N576fs	0.954:0.927:0.899:0.866:0.739:0.694:0.647:0.629:0.633:0.635:0.631:0.598:0.416:0.136:0.046:0.015	NULL	pfam_Myotubularin-like_Pase_dom,smart_Tyr_Pase_cat	0	no_errors	0	0	0	31	0	0	1	4	80	96	0	0.00	27	15	35.71
HMX3	0	genome.wustl.edu	37	10	124895626	124895627	+	Frame_Shift_Ins	INS	-	-	C			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	-	-	-	C	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	10	124895626	124895627	0	C	INS	HMX3	ENST00000357878	human	ensembl	74_37	1	known	frame_shift_ins	c.60_61	p.P23fs	0.958:0.997	NULL	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom,prints_Homeobox_metazoa	0	no_errors	0	0	0	17	0	0	6	5	45.45	27	0	0.00	42	7	14.29
WASH6P	0	genome.wustl.edu	37	X	155252253	155252253	+	RNA	SNP	C	C	T			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	X	155252253	155252253	C	T	SNP	WASH6P	ENST00000340131	human	ensembl	74_37	1	known	rna	NULL	NULL	0.77	0	0	0	no_errors	0	0	0	54	1	1.82	43	8	15.69	0	0	0.00	0	0	0.00
ENSG00000230615	0	genome.wustl.edu	37	1	44569970	44569970	+	RNA	SNP	A	A	C			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	1	44569970	44569970	A	C	SNP	ENSG00000230615	ENST00000434244	human	ensembl	74_37	1	known	rna	NULL	NULL	1	0	0	0	no_errors	0	0	0	19	0	0	22	6	21.43	0	0	0.00	0	0	0.00
DNM1P47	0	genome.wustl.edu	37	15	102304649	102304649	+	RNA	SNP	G	G	T			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	15	102304649	102304649	G	T	SNP	DNM1P47	ENST00000561463	human	ensembl	74_37	1	known	rna	NULL	NULL	1	0	0	0	no_errors	0	0	0	10	0	0	10	3	23.08	0	0	0.00	0	0	0.00
FAM230A	0	genome.wustl.edu	37	22	20710913	20710913	+	Missense_Mutation	SNP	G	G	A			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	22	20710913	20710913	G	A	SNP	FAM230A	ENST00000434783	human	ensembl	74_37	1	known	missense	c.2645	p.R882K	0.158	NULL	pfam_Ret-finger_pr-like_3_antisense,superfamily_Kinase-like_dom	0	no_errors	rs62218188	G->A	0	53	1	1.85	62	8	11.43	0	0	0.00	3	0	0.00
CTAG2	0	genome.wustl.edu	37	X	153881625	153881625	+	Frame_Shift_Del	DEL	C	C	-			TCGA-XM-AAZ2-01A-11D-A423-09	TCGA-XM-AAZ2-12A-01D-A426-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	3c2d3ad3-94dd-44c5-8194-db4fd3d95d92	ddc16e80-95c0-4d7c-b180-cd34e2927be4	X	153881625	153881625	C	0	DEL	CTAG2	ENST00000369585	human	ensembl	74_37	-1	known	frame_shift_del	c.165	p.P56fs	0	NULL	pfam_EKC/KEOPS_Pcc1	0	no_errors	0	0	0	9	0	0	4	2	33.33	0	0	0.00	2	0	0.00