Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ZNF490	57474	broad.mit.edu	37	19	12692413	12692413	+	Missense_Mutation	SNP	C	C	A			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr19:12692413C>A	ENST00000311437.6	-	5	598	c.476G>T	c.(475-477)aGt>aTt	p.S159I		NM_020714.2	NP_065765.1	Q9ULM2	ZN490_HUMAN	zinc finger protein 490	159					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(2)|endometrium(3)|kidney(1)|large_intestine(4)|lung(5)|prostate(1)|skin(1)|urinary_tract(1)	18						CCCACACACACTGCAGTCACA	0.423000													60	86					4.10029e-35	3.23199e-34	0.000781405	1	0
HRAS	3265	broad.mit.edu	37	11	533874	533874	+	Missense_Mutation	SNP	T	T	C	rs121913233		TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr11:533874T>C	ENST00000417302.1	-	3	369	c.182A>G	c.(181-183)cAg>cGg	p.Q61R	HRAS_ENST00000397596.2_Missense_Mutation_p.Q61R|HRAS_ENST00000451590.1_Missense_Mutation_p.Q61R|HRAS_ENST00000311189.7_Missense_Mutation_p.Q61R|HRAS_ENST00000468682.2_5'UTR|HRAS_ENST00000397594.1_Missense_Mutation_p.Q61R	NM_176795.3	NP_789765.1	P01112	RASH_HUMAN	Harvey rat sarcoma viral oncogene homolog	61			Q -> K (in follicular thyroid carcinoma samples; somatic mutation; increases transformation of cultured cell lines; dbSNP:rs28933406).|Q -> L (in melanoma; strongly reduced GTP hydrolysis in the presence of RAF1; increases transformation of cultured cell lines).		activation of MAPKK activity|axon guidance|blood coagulation|cell cycle arrest|cellular senescence|epidermal growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|mitotic cell cycle G1/S transition checkpoint|negative regulation of cell proliferation|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of DNA replication|positive regulation of epithelial cell proliferation|Ras protein signal transduction|synaptic transmission	cytosol|Golgi membrane|plasma membrane	GTP binding|GTPase activity|protein C-terminus binding	p.Q61R(136)|p.Q61L(117)|p.Q61P(3)		adrenal_gland(1)|bone(3)|breast(7)|cervix(23)|endometrium(4)|haematopoietic_and_lymphoid_tissue(12)|kidney(1)|large_intestine(2)|liver(1)|lung(16)|oesophagus(2)|penis(2)|pituitary(10)|prostate(31)|salivary_gland(24)|skin(184)|soft_tissue(38)|stomach(14)|testis(5)|thymus(1)|thyroid(173)|upper_aerodigestive_tract(122)|urinary_tract(225)	901		all_cancers(49;4.37e-09)|all_epithelial(84;2.09e-06)|Breast(177;0.000162)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.0538)|all_lung(207;0.0713)		all cancers(45;7.63e-28)|Epithelial(43;7.29e-27)|OV - Ovarian serous cystadenocarcinoma(40;7.15e-21)|BRCA - Breast invasive adenocarcinoma(625;3.56e-05)|Lung(200;0.0375)|LUSC - Lung squamous cell carcinoma(625;0.0703)	Sulindac(DB00605)	GTACTCCTCCTGGCCGGCGGT	0.597000	Q61L(KNS62_LUNG)|Q61L(KYSE30_OESOPHAGUS)|Q61L(NCIH1915_LUNG)	6	Mis		"""infrequent sarcomas, rare other types"""	"""rhadomyosarcoma, ganglioneuroblastoma, bladder"""			Costello syndrome	HNSCC(11;0.0054)			45	51					0	0	0.00285205	0	0
RAB3D	9545	broad.mit.edu	37	19	11446144	11446144	+	Missense_Mutation	SNP	G	G	A	rs72992916	byFrequency	TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr19:11446144G>A	ENST00000222120.3	-	4	711	c.451C>T	c.(451-453)Cgg>Tgg	p.R151W	RAB3D_ENST00000589655.1_Missense_Mutation_p.R151W	NM_004283.3	NP_004274.1	O95716	RAB3D_HUMAN	RAB3D, member RAS oncogene family	151					exocytosis|protein transport|small GTPase mediated signal transduction	plasma membrane	GTP binding|GTPase activity			cervix(1)|endometrium(3)|kidney(1)|large_intestine(3)|liver(1)|lung(3)|ovary(2)	14						GCGAGCCTCCGGCCATCCTCA	0.607000													9	32					0	0	0.000274275	0	0
ZBTB2	57621	broad.mit.edu	37	6	151686819	151686819	+	Missense_Mutation	SNP	T	T	C			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr6:151686819T>C	ENST00000325144.4	-	3	1522	c.1382A>G	c.(1381-1383)aAt>aGt	p.N461S		NM_020861.1	NP_065912.1	Q8N680	ZBTB2_HUMAN	zinc finger and BTB domain containing 2	461					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding	p.N461S(1)		breast(1)|endometrium(2)|large_intestine(2)|lung(6)|skin(1)	12			BRCA - Breast invasive adenocarcinoma(37;0.175)	OV - Ovarian serous cystadenocarcinoma(155;2.63e-11)		AACAACCTCATTGGGAGTGGA	0.473000													39	44					0	0	0.000814825	0	0
AKAP10	11216	broad.mit.edu	37	17	19835124	19835124	+	Silent	SNP	C	C	A			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr17:19835124C>A	ENST00000225737.6	-	10	1792	c.1635G>T	c.(1633-1635)gcG>gcT	p.A545A	AKAP10_ENST00000395536.3_Intron	NM_007202.3	NP_009133.2	O43572	AKA10_HUMAN	A kinase (PRKA) anchor protein 10	545					blood coagulation|protein localization	cytosol|mitochondrion|plasma membrane	signal transducer activity			NS(1)|endometrium(3)|kidney(1)|large_intestine(4)|liver(1)|lung(3)|ovary(1)|prostate(1)|skin(3)|stomach(1)|urinary_tract(2)	21	all_cancers(12;2.08e-05)|all_epithelial(12;0.00158)|Breast(13;0.165)					ATACCTGAGACGCAGAGCTGT	0.483000													18	39					3.52763e-06	2.42412e-05	0.000566183	1	0
GOLGA2B	0	broad.mit.edu	37	12	100559710	100559710	+	RNA	SNP	T	T	G			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr12:100559710T>G	ENST00000397112.4	-	0	599					NR_036632.1															large_intestine(1)|lung(3)	4						CAGAGGCTGGTGCCCGCCTTC	0.602000													5	23					0	0	0.00198382	0	0
LARP4B	23185	broad.mit.edu	37	10	863763	863763	+	Missense_Mutation	SNP	T	T	C			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr10:863763T>C	ENST00000316157.3	-	14	1637	c.1597A>G	c.(1597-1599)Agc>Ggc	p.S533G		NM_015155.1	NP_055970.1	Q92615	LAR4B_HUMAN	La ribonucleoprotein domain family, member 4B	533							nucleotide binding|RNA binding			NS(1)|breast(2)|central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(13)|lung(13)|ovary(2)|skin(2)|urinary_tract(2)	38						GGAGGGAAGCTGGACAGCCCC	0.532000													28	173					0	0	0.000720815	0	0
NUBP1	4682	broad.mit.edu	37	16	10855636	10855636	+	Missense_Mutation	SNP	C	C	T			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr16:10855636C>T	ENST00000283027.5	+	9	759	c.740C>T	c.(739-741)cCc>cTc	p.P247L	NUBP1_ENST00000571790.1_3'UTR|NUBP1_ENST00000433392.2_Missense_Mutation_p.P236L|TVP23A_ENST00000572980.1_Intron	NM_002484.2	NP_002475.2	P53384	NUBP1_HUMAN	nucleotide binding protein 1	247					cell growth|cellular iron ion homeostasis|iron-sulfur cluster assembly	cytosol	4 iron, 4 sulfur cluster binding|ATP binding|metal ion binding|nucleoside-triphosphatase activity|protein binding			large_intestine(2)|lung(3)|ovary(1)|skin(4)	10						ATATTCCCTCCCACAACCGGG	0.517000													4	75					0	0	0.00116845	0	0
OTP	23440	broad.mit.edu	37	5	76932745	76932745	+	Silent	SNP	G	G	A			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr5:76932745G>A	ENST00000306422.3	-	2	1486	c.348C>T	c.(346-348)ctC>ctT	p.L116L	OTP_ENST00000515716.1_5'UTR	NM_032109.2	NP_115485.1	Q5XKR4	OTP_HUMAN	orthopedia homeobox	116						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			endometrium(1)|kidney(1)|large_intestine(5)|lung(5)|pancreas(1)	13		all_lung(232;0.00051)|Lung NSC(167;0.000601)|Ovarian(174;0.0105)|Prostate(461;0.214)		OV - Ovarian serous cystadenocarcinoma(54;9.04e-51)|Epithelial(54;1.62e-45)|all cancers(79;4.4e-41)		CCAACTCGTTGAGCTGTGCGG	0.667000													92	97					0	0	0.000781405	0	0
ANK1	286	broad.mit.edu	37	8	41546095	41546095	+	Missense_Mutation	SNP	C	C	T			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr8:41546095C>T	ENST00000396942.1	-	34	4200	c.4117G>A	c.(4117-4119)Gaa>Aaa	p.E1373K	ANK1_ENST00000265709.8_Missense_Mutation_p.E1414K|ANK1_ENST00000396945.1_Missense_Mutation_p.E1373K|ANK1_ENST00000347528.4_Missense_Mutation_p.E1373K|ANK1_ENST00000352337.4_Missense_Mutation_p.E1373K|ANK1_ENST00000379758.2_Missense_Mutation_p.E1373K|ANK1_ENST00000289734.7_Missense_Mutation_p.E1373K			P16157	ANK1_HUMAN	ankyrin 1, erythrocytic	1373					axon guidance|cytoskeleton organization|exocytosis|maintenance of epithelial cell apical/basal polarity|signal transduction	basolateral plasma membrane|cytosol|sarcomere|sarcoplasmic reticulum|spectrin-associated cytoskeleton	cytoskeletal adaptor activity|enzyme binding|protein binding|spectrin binding|structural constituent of cytoskeleton			breast(5)|central_nervous_system(4)|endometrium(9)|kidney(1)|large_intestine(26)|lung(62)|ovary(3)|prostate(5)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(3)	122	Ovarian(28;0.00541)|Colorectal(14;0.0398)|Lung SC(25;0.211)	all_lung(54;0.000626)|Lung NSC(58;0.00245)|Esophageal squamous(32;0.0559)|Hepatocellular(245;0.0663)|Renal(179;0.188)	OV - Ovarian serous cystadenocarcinoma(14;0.000984)|Lung(22;0.00108)|Colorectal(10;0.00245)|LUSC - Lung squamous cell carcinoma(45;0.00392)|COAD - Colon adenocarcinoma(11;0.0264)			CTCCTATCTTCGGCTCCACTT	0.567000													20	18					0	0	0.00121646	0	0
SEC24D	9871	broad.mit.edu	37	4	119718931	119718931	+	Silent	SNP	T	T	C			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr4:119718931T>C	ENST00000379735.5	-	8	1222	c.951A>G	c.(949-951)acA>acG	p.T317T	SEC24D_ENST00000419654.2_5'UTR|SEC24D_ENST00000280551.6_Silent_p.T316T	NM_014822.2	NP_055637.2	O94855	SC24D_HUMAN	SEC24 family member D	316					COPII vesicle coating|intracellular protein transport|post-translational protein modification|protein N-linked glycosylation via asparagine	COPII vesicle coat|cytosol|endoplasmic reticulum membrane|Golgi membrane|perinuclear region of cytoplasm	zinc ion binding			breast(3)|cervix(1)|endometrium(5)|kidney(1)|large_intestine(10)|lung(13)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	37						GAAAACAGTATGTTGTACAAC	0.388000													10	32					0	0	0.000442599	0	0
MIR3654	0	broad.mit.edu	37	11	62344744	62344744	+	Missense_Mutation	SNP	G	G	C			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr11:62344744G>C	ENST00000496634.2	-	6	1225	c.1180C>G	c.(1180-1182)Cgt>Ggt	p.R394G	TUT1_ENST00000476907.1_Missense_Mutation_p.R394G|TUT1_ENST00000308436.7_Missense_Mutation_p.R432G																NS(1)	1						CTCAGGAAACGGGAGTTATGC	0.602000													20	15					0	0	0.00121646	0	0
IRAK3	0	broad.mit.edu	37	12	66639013	66639013	+	Missense_Mutation	SNP	C	C	T			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr12:66639013C>T	ENST00000261233.4	+	11	1706	c.1285C>T	c.(1285-1287)Cgg>Tgg	p.R429W	IRAK3_ENST00000457197.2_Missense_Mutation_p.R368W	NM_007199.2	NP_009130.2	Q9Y616	IRAK3_HUMAN	interleukin-1 receptor-associated kinase 3	429	Protein kinase.		R -> Q (may be associated with ASRT5).		interleukin-1-mediated signaling pathway|MyD88-dependent toll-like receptor signaling pathway|negative regulation of innate immune response|negative regulation of interleukin-12 production|negative regulation of interleukin-6 production|negative regulation of macrophage cytokine production|negative regulation of MAP kinase activity|negative regulation of NF-kappaB transcription factor activity|negative regulation of protein catabolic process|negative regulation of protein complex disassembly|negative regulation of toll-like receptor signaling pathway|negative regulation of tumor necrosis factor production|positive regulation of macrophage tolerance induction|positive regulation of NF-kappaB transcription factor activity|response to exogenous dsRNA|response to lipopolysaccharide|response to peptidoglycan	cytoplasm|nucleus	ATP binding|magnesium ion binding|protein heterodimerization activity|protein homodimerization activity|protein serine/threonine kinase activity			breast(3)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(4)|lung(17)|ovary(2)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)	36				GBM - Glioblastoma multiforme(28;0.0203)		TGCTGCAACGCGGGCAAAGTT	0.438000													68	79					0	0	0.000781405	0	0
TUBB8P7	0	broad.mit.edu	37	16	90161609	90161609	+	RNA	SNP	A	A	G	rs139928438	by1000genomes	TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr16:90161609A>G	ENST00000567960.1	+	0	345				TUBB8P7_ENST00000564451.1_RNA																							TGATGGAGTCAGTGATGGACG	0.617000													3	71					0	0	6.4e-05	0	0
MTSS1L	92154	broad.mit.edu	37	16	70698292	70698292	+	Missense_Mutation	SNP	A	A	C			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr16:70698292A>C	ENST00000338779.6	-	15	1806	c.1532T>G	c.(1531-1533)tTt>tGt	p.F511C	FLJ00418_ENST00000597002.1_5'UTR	NM_138383.2	NP_612392.1	Q765P7	MTSSL_HUMAN	metastasis suppressor 1-like	511					filopodium assembly|signal transduction		actin binding|cytoskeletal adaptor activity|SH3 domain binding			breast(1)|central_nervous_system(2)|endometrium(1)|liver(1)|lung(1)|skin(1)	7						TGACTTGTCAAACTCGGGCGG	0.667000													27	15					0	0	0.000720815	0	0
CSMD3	114788	broad.mit.edu	37	8	114326991	114326991	+	Silent	SNP	T	T	C			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr8:114326991T>C	ENST00000297405.5	-	2	454	c.210A>G	c.(208-210)aaA>aaG	p.K70K	CSMD3_ENST00000455883.2_Silent_p.K70K|CSMD3_ENST00000352409.3_Silent_p.K70K|CSMD3_ENST00000343508.3_Silent_p.K30K	NM_198123.1	NP_937756.1	Q7Z407	CSMD3_HUMAN	CUB and Sushi multiple domains 3	70	CUB 1.					integral to membrane|plasma membrane				breast(7)|central_nervous_system(6)|endometrium(44)|haematopoietic_and_lymphoid_tissue(8)|kidney(36)|large_intestine(72)|liver(5)|lung(389)|ovary(24)|prostate(6)|skin(23)|upper_aerodigestive_tract(19)|urinary_tract(7)	646						CATTAAGTCCTTTTAAAGTTC	0.313000										HNSCC(6;0.00088)|TCGA Ovarian(7;0.080)			3	147					0	0	6.4e-05	0	0
IGFN1	91156	broad.mit.edu	37	1	201182494	201182494	+	Missense_Mutation	SNP	G	G	T			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr1:201182494G>T	ENST00000335211.4	+	12	8603	c.8473G>T	c.(8473-8475)Gct>Tct	p.A2825S	IGFN1_ENST00000451870.2_Intron|IGFN1_ENST00000295591.8_5'UTR	NM_001164586.1	NP_001158058.1			immunoglobulin-like and fibronectin type III domain containing 1											autonomic_ganglia(2)|cervix(1)|endometrium(3)|kidney(1)|large_intestine(6)|lung(21)|ovary(2)|pancreas(1)|prostate(1)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	45						ACAGTCAGGGGCTGAGGTTGG	0.622000													10	13					2.17888e-05	0.000145985	0.000442599	1	0
IGHV3-9	0	broad.mit.edu	37	14	106552433	106552433	+	RNA	SNP	C	C	A			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr14:106552433C>A	ENST00000390600.2	-	0	285																											CCAACTAATACCTGAGACCCA	0.532000													20	147					2.94398e-08	2.07628e-07	0.000958276	1	0
PCDH20	64881	broad.mit.edu	37	13	61986868	61986868	+	Missense_Mutation	SNP	G	G	T			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr13:61986868G>T	ENST00000409186.1	-	5	3469	c.1364C>A	c.(1363-1365)aCc>aAc	p.T455N	PCDH20_ENST00000409204.4_Missense_Mutation_p.T455N			Q8N6Y1	PCD20_HUMAN	protocadherin 20	428	Cadherin 3.				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			breast(3)|central_nervous_system(2)|endometrium(3)|kidney(4)|large_intestine(14)|liver(1)|lung(23)|ovary(5)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	58		Breast(118;0.195)|Prostate(109;0.229)		GBM - Glioblastoma multiforme(99;0.000118)		ATCTCTTATGGTGAAAAACGC	0.408000													42	46					3.61848e-18	2.69376e-17	0.00170553	1	0
IGHV3-53	0	broad.mit.edu	37	14	107048673	107048673	+	RNA	SNP	C	C	T			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr14:107048673C>T	ENST00000390627.2	-	0	567																											CACTGTGTCTCTCGCACAGTA	0.567000													7	84					0	0	0.000274275	0	0
ECHDC2	55268	broad.mit.edu	37	1	53377423	53377423	+	Missense_Mutation	SNP	T	T	C			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr1:53377423T>C	ENST00000536120.1	-	5	840	c.23A>G	c.(22-24)aAt>aGt	p.N8S	ECHDC2_ENST00000358358.5_Missense_Mutation_p.N54S|ECHDC2_ENST00000371522.4_Missense_Mutation_p.N54S|ECHDC2_ENST00000541281.1_Missense_Mutation_p.N8S|ECHDC2_ENST00000480312.2_5'UTR			Q86YB7	ECHD2_HUMAN	enoyl CoA hydratase domain containing 2	54					fatty acid metabolic process	mitochondrion	lyase activity			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(3)|prostate(1)|urinary_tract(1)	12						CCCCAAGGCATTGCGGGCAGA	0.592000													39	38					0	0	0.00195071	0	0
BLMH	642	broad.mit.edu	37	17	28599594	28599594	+	Missense_Mutation	SNP	A	A	T			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr17:28599594A>T	ENST00000261714.6	-	9	1187	c.1013T>A	c.(1012-1014)cTc>cAc	p.L338H	BLMH_ENST00000394819.3_Missense_Mutation_p.L251H	NM_000386.3	NP_000377.1	Q13867	BLMH_HUMAN	bleomycin hydrolase	338					proteolysis	cytoplasm|nucleus	aminopeptidase activity|carboxypeptidase activity|cysteine-type endopeptidase activity|protein binding			breast(1)|endometrium(1)|kidney(1)|large_intestine(5)|lung(2)|ovary(1)|prostate(1)|stomach(1)	13						CATGTCACTGAGGCCCAGCTT	0.438000													129	155					0	0	0.000781405	0	0
IRS1	3667	broad.mit.edu	37	2	227661796	227661796	+	Missense_Mutation	SNP	C	C	A			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr2:227661796C>A	ENST00000305123.4	-	1	2679	c.1659G>T	c.(1657-1659)gaG>gaT	p.E553D		NM_005544.2	NP_005535.1	P35568	IRS1_HUMAN	insulin receptor substrate 1	553					fibroblast growth factor receptor signaling pathway|glucose homeostasis|insulin receptor signaling pathway|negative regulation of insulin receptor signaling pathway|negative regulation of insulin secretion|nerve growth factor receptor signaling pathway|phosphatidylinositol 3-kinase cascade|phosphatidylinositol-mediated signaling|positive regulation of fatty acid beta-oxidation|positive regulation of glucose import|positive regulation of glycogen biosynthetic process|positive regulation of insulin receptor signaling pathway|positive regulation of phosphatidylinositol 3-kinase activity	caveola|cytosol|insulin receptor complex|microsome|nucleus	insulin receptor binding|insulin-like growth factor receptor binding|phosphatidylinositol 3-kinase binding|protein kinase C binding|SH2 domain binding|transmembrane receptor protein tyrosine kinase adaptor activity			autonomic_ganglia(1)|breast(2)|central_nervous_system(4)|endometrium(5)|kidney(4)|large_intestine(10)|lung(33)|ovary(6)|pancreas(1)|prostate(1)|urinary_tract(2)	69		Renal(207;0.023)|all_lung(227;0.0994)|all_hematologic(139;0.118)|Esophageal squamous(248;0.23)		Epithelial(121;3.03e-11)|all cancers(144;2.42e-08)|Lung(261;0.00712)|LUSC - Lung squamous cell carcinoma(224;0.0137)		CAGGCATCATCTCTGTGTACT	0.622000											OREG0015248	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	49	50					3.21987e-24	2.4655e-23	0.000781405	1	0
GGT3P	0	broad.mit.edu	37	22	18769145	18769145	+	RNA	SNP	G	G	A			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr22:18769145G>A	ENST00000412448.1	-	0	1141																											TGAGGCTGCCGTTGTAGAAGG	0.612000													3	11					0	0	6.4e-05	0	0
SIGLEC12	89858	broad.mit.edu	37	19	52004780	52004780	+	Missense_Mutation	SNP	C	C	G			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr19:52004780C>G	ENST00000291707.3	-	1	263	c.208G>C	c.(208-210)Gta>Cta	p.V70L		NM_053003.2	NP_443729.1	Q96PQ1	SIG12_HUMAN	sialic acid binding Ig-like lectin 12 (gene/pseudogene)	70	Ig-like V-type 1.				cell adhesion	integral to membrane	sugar binding			NS(2)|biliary_tract(1)|breast(1)|cervix(1)|endometrium(4)|kidney(1)|large_intestine(8)|liver(1)|lung(23)|ovary(4)|prostate(2)|skin(8)|stomach(3)|upper_aerodigestive_tract(2)	61		all_neural(266;0.0199)		GBM - Glioblastoma multiforme(134;0.00161)|OV - Ovarian serous cystadenocarcinoma(262;0.0102)		TTCCGGCTTACATGGTCCCCT	0.587000													55	61					0	0	0.000781405	0	0
UBASH3B	84959	broad.mit.edu	37	11	122659945	122659945	+	Silent	SNP	C	C	T			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr11:122659945C>T	ENST00000284273.5	+	6	1284	c.909C>T	c.(907-909)acC>acT	p.T303T		NM_032873.4	NP_116262.2	Q8TF42	UBS3B_HUMAN	ubiquitin associated and SH3 domain containing B	303	SH3.					cytoplasm|nucleus	protein tyrosine phosphatase activity			breast(1)|central_nervous_system(1)|endometrium(3)|large_intestine(5)|lung(11)|prostate(1)|skin(2)|stomach(2)	26		Breast(109;0.00254)|Medulloblastoma(222;0.00877)|Lung NSC(97;0.0183)|all_lung(97;0.0186)|all_neural(223;0.0381)|all_hematologic(192;0.104)		BRCA - Breast invasive adenocarcinoma(274;1.37e-05)|OV - Ovarian serous cystadenocarcinoma(99;0.0463)		CCTTAACCACCGGCTGCTCTG	0.522000													32	188					0	0	0.00178596	0	0
COBL	23242	broad.mit.edu	37	7	51096572	51096572	+	Missense_Mutation	SNP	T	T	C			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr7:51096572T>C	ENST00000395542.2	-	12	2651	c.2467A>G	c.(2467-2469)Agt>Ggt	p.S823G	COBL_ENST00000265136.7_Missense_Mutation_p.S741G			O75128	COBL_HUMAN	cordon-bleu WH2 repeat protein	741										NS(2)|autonomic_ganglia(1)|central_nervous_system(1)|endometrium(6)|kidney(3)|large_intestine(10)|lung(26)|ovary(3)|prostate(4)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(1)	65	Glioma(55;0.08)					GCGTGAGGACTCACCAAGTTC	0.507000													43	37					0	0	0.0025221	0	0
TUBB8P7	0	broad.mit.edu	37	16	90162513	90162513	+	RNA	SNP	T	T	C			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr16:90162513T>C	ENST00000567960.1	+	0	1249				TUBB8P7_ENST00000564451.1_RNA														p.N415N(2)									GCAACATGAATGACCTGGTGT	0.537000													4	147					0	0	0.000602214	0	0
ZNF227	7770	broad.mit.edu	37	19	44739570	44739570	+	Silent	SNP	C	C	T			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr19:44739570C>T	ENST00000313040.7	+	6	1192	c.987C>T	c.(985-987)tgC>tgT	p.C329C	ZNF227_ENST00000391961.2_Silent_p.C278C|ZNF227_ENST00000589005.1_Silent_p.C278C	NM_182490.1	NP_872296.1	Q86WZ6	ZN227_HUMAN	zinc finger protein 227	329					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			central_nervous_system(1)|kidney(3)|large_intestine(4)|lung(12)|ovary(2)|stomach(1)|urinary_tract(1)	24		Prostate(69;0.0435)				GCGACAGTTGCGGCAAGGGAT	0.393000													25	43					0	0	0.00047179	0	0
RNF19B	127544	broad.mit.edu	37	1	33415316	33415316	+	Missense_Mutation	SNP	C	C	T			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr1:33415316C>T	ENST00000356990.5	-	2	694	c.695G>A	c.(694-696)gGt>gAt	p.G232D	RNF19B_ENST00000235150.4_Missense_Mutation_p.G232D|RNF19B_ENST00000373456.7_Missense_Mutation_p.G232D	NM_001127361.1	NP_001120833.1	Q6ZMZ0	RN19B_HUMAN	ring finger protein 19B	232						integral to membrane	ligase activity|protein binding|zinc ion binding			endometrium(4)|kidney(2)|large_intestine(3)|lung(4)	13		Myeloproliferative disorder(586;0.0393)|all_neural(195;0.186)				AGTCTGGCAACCTTCCCTCTC	0.488000													39	31					0	0	0.00111076	0	0
RORB	6096	broad.mit.edu	37	9	77257585	77257585	+	Missense_Mutation	SNP	C	C	T			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr9:77257585C>T	ENST00000376896.2	+	4	1103	c.491C>T	c.(490-492)tCc>tTc	p.S164F	RORB_ENST00000396204.2_Missense_Mutation_p.S175F	NM_006914.3	NP_008845.2	Q92753	RORB_HUMAN	RAR-related orphan receptor B	175	Hinge (Potential).				eye photoreceptor cell development|positive regulation of transcription, DNA-dependent|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor|visual perception	nucleoplasm	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|zinc ion binding			breast(2)|large_intestine(4)|lung(1)|ovary(2)|skin(2)|upper_aerodigestive_tract(1)	12						GGTCAGCCGTCCCCTGATCAG	0.493000													28	40					0	0	0.000878237	0	0
CAMK2A	815	broad.mit.edu	37	5	149669141	149669141	+	Silent	SNP	G	G	A			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr5:149669141G>A	ENST00000348628.6	-	1	713	c.48C>T	c.(46-48)ttC>ttT	p.F16F	CAMK2A_ENST00000398376.3_Silent_p.F16F	NM_015981.3|NM_171825.2	NP_057065.2|NP_741960.1	Q9UQM7	KCC2A_HUMAN	calcium/calmodulin-dependent protein kinase II alpha	16	Protein kinase.				interferon-gamma-mediated signaling pathway|positive regulation of NF-kappaB transcription factor activity|synaptic transmission	cell junction|cytosol|endocytic vesicle membrane|nucleoplasm|presynaptic membrane	ATP binding|calmodulin binding|calmodulin-dependent protein kinase activity			cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(6)|skin(1)|stomach(1)	15		all_hematologic(541;0.224)	KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			CCAATTCCTCGAAGAGCTGGT	0.632000													43	37					0	0	0.000781405	0	0
TG	7038	broad.mit.edu	37	8	133900509	133900510	+	Frame_Shift_Ins	INS	-	-	T			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr8:133900509_133900510insT	ENST00000220616.4	+	10	2497_2498	c.2457_2458insT	c.(2455-2460)ctttatfs	p.Y820fs	TG_ENST00000377869.1_Frame_Shift_Ins_p.Y820fs	NM_003235.4	NP_003226.4	P01266	THYG_HUMAN	thyroglobulin	820	Thyroglobulin type-1 7.				hormone biosynthetic process|signal transduction|thyroid gland development|thyroid hormone generation	extracellular space	hormone activity			NS(1)|breast(11)|central_nervous_system(3)|endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(34)|liver(2)|lung(59)|ovary(9)|pancreas(2)|prostate(6)|skin(7)|stomach(4)|upper_aerodigestive_tract(4)|urinary_tract(8)	168	Ovarian(258;0.00438)|Acute lymphoblastic leukemia(118;0.155)	Myeloproliferative disorder(644;0.00878)|Acute lymphoblastic leukemia(644;0.0559)|Breast(495;0.0735)	BRCA - Breast invasive adenocarcinoma(115;0.000701)	KIRC - Kidney renal clear cell carcinoma(542;0.0546)		ACTTCAGTCTCTTTATTCAAAG	0.515													34	50	---	---	---	---					
ATRNL1	26033	broad.mit.edu	37	10	117226764	117226765	+	Splice_Site	INS	-	-	A			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr10:117226764_117226765insA	ENST00000355044.3	+	23	3622		c.e23+2		ATRNL1_ENST00000423111.2_Splice_Site|ATRNL1_ENST00000303745.7_Intron	NM_207303.2	NP_997186.1	Q5VV63	ATRN1_HUMAN	attractin-like 1							integral to membrane	sugar binding			NS(1)|breast(1)|central_nervous_system(2)|cervix(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(8)|large_intestine(11)|liver(2)|lung(44)|ovary(6)|prostate(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	95		all_lung(145;0.0686)|Breast(234;0.0969)|Lung NSC(174;0.17)|Colorectal(252;0.234)		Epithelial(162;0.00031)|all cancers(201;0.000753)|LUSC - Lung squamous cell carcinoma(1;0.0515)|Lung(30;0.0827)		GTTCAACAGGTAAAAAAATGTT	0.287													2	4	---	---	---	---					
PAN3	255967	broad.mit.edu	37	13	28713125	28713125	+	Frame_Shift_Del	DEL	C	C	-			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr13:28713125delC	ENST00000380958.3	+	1	483	c.331delC	c.(331-333)ccfs	p.P112fs		NM_175854.7	NP_787050.6	Q58A45	PAN3_HUMAN	PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)	112	Interaction with polyadenylate-binding protein.				nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|nuclear-transcribed mRNA poly(A) tail shortening	centrosome|cytosol	ATP binding|protein kinase activity			endometrium(1)|kidney(3)|large_intestine(7)|lung(9)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	24	Acute lymphoblastic leukemia(6;0.04)	Lung SC(185;0.0262)	Colorectal(13;0.000334)	all cancers(112;0.0102)|Epithelial(112;0.0803)|GBM - Glioblastoma multiforme(144;0.121)|OV - Ovarian serous cystadenocarcinoma(117;0.13)|Lung(94;0.174)		AGCTGGGCCGCCCCCCGGGCC	0.771													2	4	---	---	---	---					
RTL1	388015	broad.mit.edu	37	14	101350670	101350671	+	In_Frame_Ins	INS	-	-	TCT	rs55755518	by1000genomes	TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr14:101350670_101350671insTCT	ENST00000534062.1	-	1	513_514	c.455_456insAGA	c.(454-456)gca>gAGAca	p.152_152A>ET		NM_001134888.2	NP_001128360.1	E9PKS8	E9PKS8_HUMAN	retrotransposon-like 1	152										breast(1)|endometrium(5)|kidney(4)|large_intestine(1)|lung(5)|pancreas(1)|prostate(2)|skin(2)	21						TCTGGTTTTGCTCTTGAGGAGT	0.520													2	4	---	---	---	---					
RP11-640N20.9	0	broad.mit.edu	37	17	30439692	30439693	+	RNA	INS	-	-	GAGGC	rs150029068	by1000genomes	TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr17:30439692_30439693insGAGGC	ENST00000580412.1	-	0	43																											GGGCCAGCGCTGAGGCCGCCGC	0.589													4	5	---	---	---	---					
SPPL2B	56928	broad.mit.edu	37	19	2337757	2337757	+	RNA	DEL	G	G	-			TCGA-EM-A2CM-01A-11D-A17V-08	TCGA-EM-A2CM-10A-01D-A17V-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	38326783-dcfb-406b-8c84-137e909da09f	283aa2e1-e1f6-444c-b64d-9c1571247c1b	g.chr19:2337757delG	ENST00000452401.2	+	0	449				AC005258.3_ENST00000590001.1_RNA			Q8TCT7	PSL1_HUMAN	signal peptide peptidase like 2B							Golgi membrane|integral to membrane	aspartic-type endopeptidase activity						Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		GGGAGGATCTGGGCCGAGTGT	0.637													3	3	---	---	---	---