Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID Genome_Change Annotation_Transcript Transcript_Strand Transcript_Exon Transcript_Position cDNA_Change Codon_Change Protein_Change Other_Transcripts Refseq_mRNA_Id Refseq_prot_Id SwissProt_acc_Id SwissProt_entry_Id Description UniProt_AApos UniProt_Region UniProt_Site UniProt_Natural_Variations UniProt_Experimental_Info GO_Biological_Process GO_Cellular_Component GO_Molecular_Function COSMIC_overlapping_mutations COSMIC_fusion_genes COSMIC_tissue_types_affected COSMIC_total_alterations_in_gene Tumorscape_Amplification_Peaks Tumorscape_Deletion_Peaks TCGAscape_Amplification_Peaks TCGAscape_Deletion_Peaks DrugBank ref_context gc_content CCLE_ONCOMAP_overlapping_mutations CCLE_ONCOMAP_total_mutations_in_gene CGC_Mutation_Type CGC_Translocation_Partner CGC_Tumor_Types_Somatic CGC_Tumor_Types_Germline CGC_Other_Diseases DNARepairGenes_Role FamilialCancerDatabase_Syndromes MUTSIG_Published_Results OREGANNO_ID OREGANNO_Values t_alt_count t_ref_count validation_alt_allele validation_method validation_status validation_tumor_sample pox qox pox_cutoff isArtifactMode oxoGCut NCOA6 23054 broad.mit.edu 37 20 33345744 33345744 + Silent SNP C C T TCGA-E8-A416-01A-11D-A23M-08 TCGA-E8-A416-10A-01D-A23K-08 Untested Somatic Phase_I WXS none Illumina GAIIx c8381701-31cb-465a-bdf2-1b8132be7a14 d60fc127-2b47-4ce1-a120-f43adc2ae776 g.chr20:33345744C>T ENST00000374796.2 - 8 3377 c.807G>A c.(805-807)caG>caA p.Q269Q NCOA6_ENST00000359003.2_Silent_p.Q269Q Q14686 NCOA6_HUMAN nuclear receptor coactivator 6 269 CREBBP-binding region.|Gln-rich.|NCOA1-binding region.|TBP/GTF2A-binding region. brain development|cellular lipid metabolic process|DNA recombination|DNA repair|DNA replication|estrogen receptor signaling pathway|glucocorticoid receptor signaling pathway|heart development|myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|response to hormone stimulus|transcription initiation from RNA polymerase II promoter transcription factor complex chromatin binding|enzyme binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|retinoid X receptor binding|thyroid hormone receptor binding p.Q269Q(15) NS(2)|breast(6)|central_nervous_system(3)|cervix(1)|endometrium(9)|kidney(8)|large_intestine(16)|lung(37)|ovary(4)|prostate(5)|skin(13)|upper_aerodigestive_tract(2)|urinary_tract(1) 107 gctgctgctgctgttgttgtt 0.537000 4 41 0 0 1 0 0 ANKRD30B 374860 broad.mit.edu 37 18 14752601 14752601 + Silent SNP A A G TCGA-E8-A416-01A-11D-A23M-08 TCGA-E8-A416-10A-01D-A23K-08 Untested Somatic Phase_I WXS none Illumina GAIIx c8381701-31cb-465a-bdf2-1b8132be7a14 d60fc127-2b47-4ce1-a120-f43adc2ae776 g.chr18:14752601A>G ENST00000358984.4 + 2 438 c.258A>G c.(256-258)gcA>gcG p.A86A ANKRD30B_ENST00000579292.1_Intron|ANKRD30B_ENST00000447268.2_Silent_p.A86A NM_001145029.1 NP_001138501.1 Q9BXX2 AN30B_HUMAN ankyrin repeat domain 30B 86 breast(3)|endometrium(4)|kidney(3)|lung(8)|ovary(1)|prostate(2)|skin(1) 22 ATGGCCATGCAGAAGTAGTAA 0.448000 3 26 0 0 1 0 0 CDCA7 83879 broad.mit.edu 37 2 174223463 174223463 + Silent SNP G G A rs139753635 byFrequency TCGA-E8-A416-01A-11D-A23M-08 TCGA-E8-A416-10A-01D-A23K-08 Untested Somatic Phase_I WXS none Illumina GAIIx c8381701-31cb-465a-bdf2-1b8132be7a14 d60fc127-2b47-4ce1-a120-f43adc2ae776 g.chr2:174223463G>A ENST00000306721.3 + 2 148 c.45G>A c.(43-45)aaG>aaA p.K15K CDCA7_ENST00000392567.2_Silent_p.K15K|CDCA7_ENST00000347703.3_Silent_p.K15K|CDCA7_ENST00000410101.3_Silent_p.K15K|CDCA7_ENST00000410019.3_Intron NM_031942.4 NP_114148.3 Q9BWT1 CDCA7_HUMAN cell division cycle associated 7 0 regulation of cell proliferation|regulation of transcription, DNA-dependent|transcription, DNA-dependent nucleus breast(1)|endometrium(2)|kidney(2)|large_intestine(4)|lung(8)|ovary(1) 18 OV - Ovarian serous cystadenocarcinoma(117;0.116) GAGTAAAGAAGAACTTAAAGA 0.328000 4 58 0 0 1 0 0 RP11-113D6.10 0 broad.mit.edu 37 11 18231289 18231289 + Missense_Mutation SNP C C A rs4757627 by1000genomes TCGA-E8-A416-01A-11D-A23M-08 TCGA-E8-A416-10A-01D-A23K-08 Untested Somatic Phase_I WXS none Illumina GAIIx c8381701-31cb-465a-bdf2-1b8132be7a14 d60fc127-2b47-4ce1-a120-f43adc2ae776 g.chr11:18231289C>A ENST00000527059.1 + 1 535 c.75C>A c.(73-75)ttC>ttA p.F25L RP11-113D6.10_ENST00000340135.3_Missense_Mutation_p.F25L|RP11-113D6.10_ENST00000534640.1_Missense_Mutation_p.F25L CTAACATCTTCGAAACAAGAT 0.363000 6 52 0.0215528 0.0215528 1 1 0 MICAL1 64780 broad.mit.edu 37 6 109767929 109767929 + Silent SNP C C T rs41288556 byFrequency TCGA-E8-A416-01A-11D-A23M-08 TCGA-E8-A416-10A-01D-A23K-08 Untested Somatic Phase_I WXS none Illumina GAIIx c8381701-31cb-465a-bdf2-1b8132be7a14 d60fc127-2b47-4ce1-a120-f43adc2ae776 g.chr6:109767929C>T ENST00000368952.4 - 18 2621 c.2331G>A c.(2329-2331)gcG>gcA p.A777A MICAL1_ENST00000358577.3_Silent_p.A672A|MICAL1_ENST00000358807.3_Silent_p.A758A Q8TDZ2 MICA1_HUMAN microtubule associated monooxygenase, calponin and LIM domain containing 1 758 cytoskeleton organization|signal transduction cytoplasm|intermediate filament SH3 domain binding|zinc ion binding NS(1)|breast(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(6)|liver(1)|lung(7)|ovary(3)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(2) 40 all_cancers(87;0.000189)|Acute lymphoblastic leukemia(125;3.07e-08)|all_hematologic(75;3.33e-06)|all_epithelial(87;0.00686)|Lung SC(18;0.0743)|Colorectal(196;0.101)|all_lung(197;0.149) Epithelial(106;0.0142)|all cancers(137;0.0197)|OV - Ovarian serous cystadenocarcinoma(136;0.0233)|BRCA - Breast invasive adenocarcinoma(108;0.0574) CGCTGCCTTCCGCTTTGTGGT 0.572000 3 21 0 0 1 0 0 RP11-404F10.2 0 broad.mit.edu 37 1 160640798 160640798 + RNA DEL T T - TCGA-E8-A416-01A-11D-A23M-08 TCGA-E8-A416-10A-01D-A23K-08 Untested Somatic Phase_I WXS none Illumina GAIIx c8381701-31cb-465a-bdf2-1b8132be7a14 d60fc127-2b47-4ce1-a120-f43adc2ae776 g.chr1:160640798delT ENST00000598917.1 + 0 231 TTCTGAACAATTTTTTTTTTA 0.428 2 4 --- --- --- --- RP11-697E22.2 0 broad.mit.edu 37 17 36003613 36003614 + RNA INS - - T rs10543338 TCGA-E8-A416-01A-11D-A23M-08 TCGA-E8-A416-10A-01D-A23K-08 Untested Somatic Phase_I WXS none Illumina GAIIx c8381701-31cb-465a-bdf2-1b8132be7a14 d60fc127-2b47-4ce1-a120-f43adc2ae776 g.chr17:36003613_36003614insT ENST00000586163.1 + 0 590 RP11-697E22.2_ENST00000586950.1_RNA CATTAtttatcttttttttttt 0.510 2 4 --- --- --- ---