Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ZXDA	7789	broad.mit.edu	37	X	57936620	57936620	+	Missense_Mutation	SNP	G	G	C	rs151072020		TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chrX:57936620G>C	ENST00000358697.4	-	1	447	c.235C>G	c.(235-237)Cat>Gat	p.H79D		NM_007156.4	NP_009087.1	P98168	ZXDA_HUMAN	zinc finger, X-linked, duplicated A	79					positive regulation of transcription, DNA-dependent	nucleus	C2H2 zinc finger domain binding|identical protein binding|nucleic acid binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(2)|endometrium(9)|kidney(1)|large_intestine(7)|lung(13)|ovary(2)|prostate(2)|skin(1)	37						CTAGGTTGATGGGGCCTCGGC	0.756000													3	23					0	0	1	0	0
NDUFAF2	91942	broad.mit.edu	37	5	60241050	60241050	+	Translation_Start_Site	SNP	G	G	A			TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chr5:60241050G>A	ENST00000296597.5	+	0	95				NDUFAF2_ENST00000511107.1_De_novo_Start_OutOfFrame	NM_174889.4	NP_777549.1	Q8N183	MIMIT_HUMAN	NADH dehydrogenase (ubiquinone) complex I, assembly factor 2							membrane|mitochondrion	electron carrier activity|NADH dehydrogenase (ubiquinone) activity			central_nervous_system(1)|endometrium(1)|kidney(2)|large_intestine(1)|ovary(1)	6		Lung NSC(810;3.36e-05)|Prostate(74;0.0225)|Ovarian(174;0.17)|Breast(144;0.237)				TGCGGGTCCCGCTGCTGGCAG	0.632000													3	14					0	0	1	0	0
DHX16	8449	broad.mit.edu	37	6	30633345	30633345	+	Missense_Mutation	SNP	C	C	G			TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chr6:30633345C>G	ENST00000376442.3	-	5	1027	c.832G>C	c.(832-834)Gat>Cat	p.D278H		NM_001164239.1|NM_003587.4	NP_001157711.1|NP_003578.2	O60231	DHX16_HUMAN	DEAH (Asp-Glu-Ala-His) box polypeptide 16	278					mRNA processing|RNA splicing	nucleus	ATP binding|ATP-dependent helicase activity|nucleic acid binding|RNA helicase activity			kidney(2)|ovary(2)	4						CGGGCGAGATCCCGCACTCGC	0.632000													12	58					0	0	1	0	0
LL22NC03-80A10.6	0	broad.mit.edu	37	22	22664606	22664606	+	RNA	SNP	A	A	G			TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chr22:22664606A>G	ENST00000426066.1	+	0	787					NR_027293.1																						GTCTTCATGCAAACTTGGTAT	0.398000													3	26					0	0	1	0	0
ADAMDEC1	27299	broad.mit.edu	37	8	24250806	24250806	+	Missense_Mutation	SNP	T	T	C			TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chr8:24250806T>C	ENST00000256412.4	+	3	459	c.239T>C	c.(238-240)aTg>aCg	p.M80T	RP11-624C23.1_ENST00000519689.1_RNA|ADAMDEC1_ENST00000522298.1_Start_Codon_SNP_p.M1T|RP11-624C23.1_ENST00000523578.1_RNA|ADAMDEC1_ENST00000538205.1_Start_Codon_SNP_p.M1T	NM_014479.3	NP_055294.1	O15204	ADEC1_HUMAN	ADAM-like, decysin 1	80					integrin-mediated signaling pathway|negative regulation of cell adhesion|proteolysis	extracellular region|integral to membrane	integrin binding|metalloendopeptidase activity|zinc ion binding			NS(1)|breast(1)|large_intestine(4)|skin(2)|stomach(1)	9		Prostate(55;0.0181)		Colorectal(74;0.016)|COAD - Colon adenocarcinoma(73;0.0646)|BRCA - Breast invasive adenocarcinoma(99;0.168)		CAATATCAGATGATCTTAAAT	0.303000													6	53					0	0	1	0	0
LIN37	55957	broad.mit.edu	37	19	36245363	36245363	+	Silent	SNP	C	C	T			TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chr19:36245363C>T	ENST00000301159.9	+	9	1093	c.729C>T	c.(727-729)taC>taT	p.Y243Y	AC002398.9_ENST00000591613.2_3'UTR	NM_019104.2	NP_061977.1	Q96GY3	LIN37_HUMAN	lin-37 homolog (C. elegans)	243							protein binding			large_intestine(1)|lung(5)	6	all_lung(56;3.33e-07)|Lung NSC(56;5.02e-07)|Esophageal squamous(110;0.162)		LUSC - Lung squamous cell carcinoma(66;0.0515)			GAGAGATGTACGAACGACAGT	0.577000													6	25					0	0	1	0	0
COTL1	23406	broad.mit.edu	37	16	84600451	84600451	+	Nonstop_Mutation	SNP	T	T	G			TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chr16:84600451T>G	ENST00000262428.4	-	4	591	c.429A>C	c.(427-429)taA>taC	p.*143Y	COTL1_ENST00000567278.1_5'UTR|COTL1_ENST00000564057.1_Nonstop_Mutation_p.*74Y	NM_021149.2	NP_066972.1	Q14019	COTL1_HUMAN	coactosin-like 1 (Dictyostelium)	0						cytoplasm|cytoskeleton	actin binding|enzyme binding			endometrium(1)|large_intestine(1)|liver(1)|lung(2)|skin(1)	6						GGGGCTGGGGTTACTCCGTCT	0.622000													7	18					0	0	1	0	0
ANKRD30B	374860	broad.mit.edu	37	18	14779969	14779969	+	Missense_Mutation	SNP	C	C	G	rs9675365	by1000genomes	TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chr18:14779969C>G	ENST00000358984.4	+	11	1611	c.1431C>G	c.(1429-1431)ttC>ttG	p.F477L	ANKRD30B_ENST00000579292.1_Intron|ANKRD30B_ENST00000447268.2_Missense_Mutation_p.F477L	NM_001145029.1	NP_001138501.1	Q9BXX2	AN30B_HUMAN	ankyrin repeat domain 30B	477			F -> L (in dbSNP:rs9675365).					p.F477L(2)		breast(3)|endometrium(4)|kidney(3)|lung(8)|ovary(1)|prostate(2)|skin(1)	22						ATCAGATGTTCCCATCAGAAT	0.279000													7	13					0	0	1	0	0
ZNF74	7625	broad.mit.edu	37	22	20759722	20759722	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chr22:20759722G>A	ENST00000403682.3	+	4	814	c.313G>A	c.(313-315)Ggc>Agc	p.G105S	ZNF74_ENST00000405993.1_Silent_p.P101P|ZNF74_ENST00000400451.2_Silent_p.P133P|ZNF74_ENST00000356671.5_Silent_p.P133P|ZNF74_ENST00000357502.5_Missense_Mutation_p.G139S	NM_001256523.1	NP_001243452.1	Q16587	ZNF74_HUMAN	zinc finger protein 74	0	KRAB.				multicellular organismal development|regulation of transcription, DNA-dependent|transcription, DNA-dependent	actin cytoskeleton|nucleus	DNA binding|RNA binding|zinc ion binding			central_nervous_system(1)|cervix(1)|endometrium(3)|large_intestine(4)|lung(7)|ovary(1)|skin(1)|urinary_tract(1)	19	Melanoma(16;0.000465)|Ovarian(15;0.0025)|Colorectal(54;0.0221)|all_neural(72;0.219)	Lung SC(17;0.0262)|all_lung(157;0.248)	LUSC - Lung squamous cell carcinoma(15;0.00102)|Lung(15;0.0173)			AAGAAGAACCGGCCCAGGAGC	0.627000													14	59					0	0	1	0	0
ZXDA	7789	broad.mit.edu	37	X	57936633	57936633	+	Missense_Mutation	SNP	G	G	C			TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chrX:57936633G>C	ENST00000358697.4	-	1	434	c.222C>G	c.(220-222)ttC>ttG	p.F74L		NM_007156.4	NP_009087.1	P98168	ZXDA_HUMAN	zinc finger, X-linked, duplicated A	74					positive regulation of transcription, DNA-dependent	nucleus	C2H2 zinc finger domain binding|identical protein binding|nucleic acid binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(2)|endometrium(9)|kidney(1)|large_intestine(7)|lung(13)|ovary(2)|prostate(2)|skin(1)	37						GCCTCGGCGCGAACAGGCTTG	0.761000													3	21					0	0	1	0	0
HLA-A	3105	broad.mit.edu	37	6	29910693	29910693	+	Missense_Mutation	SNP	A	A	G	rs41559716	by1000genomes	TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chr6:29910693A>G	ENST00000396634.1	+	4	574	c.233A>G	c.(232-234)cAg>cGg	p.Q78R	HLA-A_ENST00000376802.2_Missense_Mutation_p.Q78R|HLA-A_ENST00000376806.5_Missense_Mutation_p.Q78R|HLA-A_ENST00000376809.5_Missense_Mutation_p.Q78R			P30443	1A01_HUMAN	major histocompatibility complex, class I, A	78	Alpha-1.				antigen processing and presentation of peptide antigen via MHC class I|interferon-gamma-mediated signaling pathway|interspecies interaction between organisms|regulation of immune response|type I interferon-mediated signaling pathway	integral to plasma membrane|MHC class I protein complex	MHC class I receptor activity	p.Q78R(2)		central_nervous_system(2)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(10)|ovary(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(5)|urinary_tract(2)	30						TGGATAGAGCAGGAGGGGCCG	0.657000									Osteosarcoma, Familial Clustering of;Naso-/Oropharyngeal/Laryngeal Cancer, Familial Clustering of;Melanoma, Familial Clustering of;Lichen Sclerosis et Atrophicus, Familial Clustering of	Multiple Myeloma(9;0.094)			3	13					0	0	1	0	0
KCND3	3752	broad.mit.edu	37	1	112318869	112318869	+	Missense_Mutation	SNP	C	C	T	rs149344567		TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chr1:112318869C>T	ENST00000369697.1	-	6	1810	c.1741G>A	c.(1741-1743)Gga>Aga	p.G581R	KCND3_ENST00000302127.4_Missense_Mutation_p.G581R|KCND3_ENST00000315987.2_Missense_Mutation_p.G600R			Q9UK17	KCND3_HUMAN	potassium voltage-gated channel, Shal-related subfamily, member 3	600						sarcolemma|voltage-gated potassium channel complex	A-type (transient outward) potassium channel activity|metal ion binding			NS(1)|breast(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(3)|kidney(3)|large_intestine(16)|lung(9)|ovary(2)|prostate(2)|skin(1)|upper_aerodigestive_tract(4)|urinary_tract(2)	49		all_cancers(81;8.52e-06)|all_epithelial(167;5.65e-06)|all_lung(203;2.72e-05)|Lung NSC(69;4.56e-05)		all cancers(265;0.056)|Lung(183;0.0576)|Colorectal(144;0.1)|Epithelial(280;0.104)|COAD - Colon adenocarcinoma(174;0.222)|LUSC - Lung squamous cell carcinoma(189;0.231)		GGTCTCAGTCCGTCGTCTGCT	0.562000													4	41					0	0	1	0	0
PMS2P3	0	broad.mit.edu	37	7	75142142	75142142	+	RNA	DEL	A	A	-	rs35519730		TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chr7:75142142delA	ENST00000418756.1	-	0	991					NR_028059.1															lung(1)	1						tctcaaaaagaaaaaaaaaaa	0.418													3	3	---	---	---	---					
JAM2	58494	broad.mit.edu	37	21	27012164	27012166	+	In_Frame_Del	DEL	CTG	CTG	-			TCGA-DJ-A4UP-01A-11D-A257-08	TCGA-DJ-A4UP-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee4bf1b6-4123-4c18-987a-f814b572a708	eaf8980b-fe88-4642-ba40-8b94e462e275	g.chr21:27012164_27012166delCTG	ENST00000480456.1	+	1	581_583	c.31_33delCTG	c.(31-33)del	p.L14del	JAM2_ENST00000400532.1_In_Frame_Del_p.L14del|JAM2_ENST00000425221.2_In_Frame_Del_p.L14del|JAM2_ENST00000312957.5_In_Frame_Del_p.L14del	NM_001270407.1|NM_021219.3	NP_001257336.1|NP_067042.1	P57087	JAM2_HUMAN	junctional adhesion molecule 2	14					blood coagulation|cell-cell adhesion|leukocyte migration	integral to plasma membrane|tight junction				endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(1)|lung(12)|prostate(1)|stomach(1)|urinary_tract(1)	19						CCGCCTCCTCCTGCTGCTGCTGC	0.724													2	4	---	---	---	---