Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ODZ2	57451	broad.mit.edu	37	5	167645509	167645509	+	Missense_Mutation	SNP	C	C	T			TCGA-J8-A4HW-06A-11D-A257-08	TCGA-J8-A4HW-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	cd7d1d09-5c2b-414d-9ec2-e7a7d5665671	269e9978-ced5-4398-9523-947b064a3ca8	g.chr5:167645509C>T	uc010jjd.3	+	22	4586	c.4586C>T	c.(4585-4587)gCg>gTg	p.A1529V	ODZ2_uc003lzr.4_Missense_Mutation_p.A1299V|ODZ2_uc003lzt.4_Missense_Mutation_p.A902V|ODZ2_uc010jje.3_Missense_Mutation_p.A793V	NM_001122679	NP_001116151			Homo sapiens odz, odd Oz/ten-m homolog 2 (Drosophila) (ODZ2), mRNA.											NS(1)|autonomic_ganglia(1)|breast(5)|central_nervous_system(4)|cervix(2)|endometrium(11)|haematopoietic_and_lymphoid_tissue(3)|kidney(3)|large_intestine(29)|lung(45)|ovary(8)|pancreas(1)|prostate(3)|skin(2)|stomach(2)|urinary_tract(2)	122	Renal(175;0.00124)|Lung NSC(126;0.136)|all_lung(126;0.242)	Medulloblastoma(196;0.0241)|all_neural(177;0.026)	Kidney(164;7.53e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)	all cancers(165;0.0444)|OV - Ovarian serous cystadenocarcinoma(192;0.0694)|Epithelial(171;0.124)		GATGCCTACGCGACTGATGCC	0.502000													32	146					0	0	1	0	0
ADARB1	104	broad.mit.edu	37	21	46591540	46591540	+	Missense_Mutation	SNP	G	G	A			TCGA-J8-A4HW-06A-11D-A257-08	TCGA-J8-A4HW-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	cd7d1d09-5c2b-414d-9ec2-e7a7d5665671	269e9978-ced5-4398-9523-947b064a3ca8	g.chr21:46591540G>A	uc011afo.1	+	1	117	c.116G>A	c.(115-117)cGc>cAc	p.R39H	ADARB1_uc002zgs.2_Non-coding_Transcript|ADARB1_uc002zgw.2_5'UTR|ADARB1_uc002zgv.2_Non-coding_Transcript|ADARB1_uc002zgt.2_5'UTR|ADARB1_uc010gpx.2_Non-coding_Transcript|ADARB1_uc002zgr.2_5'UTR|ADARB1_uc002zgq.2_Non-coding_Transcript|ADARB1_uc002zgu.2_Non-coding_Transcript|ADARB1_uc002zgy.2_5'UTR	NM_001160230	NP_001153702	P78563	RED1_HUMAN	Homo sapiens adenosine deaminase, RNA-specific, B1 (ADARB1), transcript variant 7, mRNA.	84					RNA processing|adenosine to inosine editing|mRNA modification|mRNA processing	nucleoplasm|nucleus	RNA binding|double-stranded RNA adenosine deaminase activity|double-stranded RNA binding|mRNA binding|metal ion binding			endometrium(4)|kidney(1)|large_intestine(3)|lung(8)|skin(1)	17				Colorectal(79;0.115)		AACAGTCTCCGCCAGTCAAGA	0.358000													13	43					0	0	1	0	0
MED15	51586	broad.mit.edu	37	22	20891439	20891439	+	Missense_Mutation	SNP	G	G	T			TCGA-J8-A4HW-06A-11D-A257-08	TCGA-J8-A4HW-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	cd7d1d09-5c2b-414d-9ec2-e7a7d5665671	269e9978-ced5-4398-9523-947b064a3ca8	g.chr22:20891439G>T	uc002zsp.3	+	1	184	c.104G>T	c.(103-105)aGt>aTt	p.S35I	MED15_uc002zsn.1_5'UTR|MED15_uc002zso.2_Missense_Mutation_p.S35I|MED15_uc002zsq.3_Missense_Mutation_p.S35I|MED15_uc010gso.3_Missense_Mutation_p.S35I|MED15_uc002zsr.3_Missense_Mutation_p.S9I|MED15_uc011ahs.2_Missense_Mutation_p.S9I|MED15_uc011aht.1_Missense_Mutation_p.S9I	NM_001003891	NP_001003891	Q96RN5	MED15_HUMAN	Homo sapiens mediator complex subunit 15 (MED15), transcript variant 1, mRNA.	35	Interaction with SREBF1.				regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	Golgi apparatus|mediator complex	protein binding			central_nervous_system(1)|endometrium(5)|kidney(3)|large_intestine(2)|lung(8)|ovary(1)|prostate(1)|skin(3)|urinary_tract(1)	25	all_cancers(11;2.07e-24)|Melanoma(16;0.000465)|Ovarian(15;0.00167)|Colorectal(54;0.0221)|all_neural(72;0.142)	Lung SC(17;0.0262)	LUSC - Lung squamous cell carcinoma(15;0.00102)|Lung(15;0.0173)|Epithelial(17;0.209)			GTGGCACACAGTAAATCCAGC	0.552000													11	65					0	0	1	0	0
CYP19A1	1588	broad.mit.edu	37	15	51520089	51520089	+	Missense_Mutation	SNP	C	C	A			TCGA-J8-A4HW-06A-11D-A257-08	TCGA-J8-A4HW-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	cd7d1d09-5c2b-414d-9ec2-e7a7d5665671	269e9978-ced5-4398-9523-947b064a3ca8	g.chr15:51520089C>A	uc001zyz.4	-	4	589	c.338G>T	c.(337-339)aGc>aTc	p.S113I	CYP19A1_uc001zza.4_Missense_Mutation_p.S113I|CYP19A1_uc001zzb.2_Missense_Mutation_p.S113I|CYP19A1_uc001zzd.3_Missense_Mutation_p.S113I|CYP19A1_uc010bey.1_Missense_Mutation_p.S113I	NM_031226	NP_112503	P11511	CP19A_HUMAN	Homo sapiens cytochrome P450, family 19, subfamily A, polypeptide 1 (CYP19A1), transcript variant 2, mRNA.	113					estrogen biosynthetic process|xenobiotic metabolic process	endoplasmic reticulum membrane|membrane fraction	aromatase activity|electron carrier activity|heme binding|oxygen binding|steroid hydroxylase activity			endometrium(1)|kidney(4)|large_intestine(9)|lung(11)|prostate(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(2)	33				all cancers(107;0.000372)|GBM - Glioblastoma multiforme(94;0.0128)	Aminoglutethimide(DB00357)|Anastrozole(DB01217)|Conjugated Estrogens(DB00286)|Danazol(DB01406)|Diethylstilbestrol(DB00255)|Exemestane(DB00990)|Letrozole(DB01006)|Testolactone(DB00894)|Testosterone(DB00624)	GAATCGAGAGCTGTAATGATT	0.443000													7	56					0	0	1	0	0
OAS2	4939	broad.mit.edu	37	12	113425106	113425106	+	Silent	SNP	C	C	T			TCGA-J8-A4HW-06A-11D-A257-08	TCGA-J8-A4HW-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	cd7d1d09-5c2b-414d-9ec2-e7a7d5665671	269e9978-ced5-4398-9523-947b064a3ca8	g.chr12:113425106C>T	uc001tuj.3	+	1	581	c.441C>T	c.(439-441)aaC>aaT	p.N147N	OAS2_uc001tuh.3_Silent_p.N147N|OAS2_uc001tui.1_Silent_p.N147N	NM_016817	NP_058197	P29728	OAS2_HUMAN	Homo sapiens 2'-5'-oligoadenylate synthetase 2, 69/71kDa (OAS2), transcript variant 1, mRNA.	147	OAS domain 1.				interferon-gamma-mediated signaling pathway|nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|type I interferon-mediated signaling pathway	endoplasmic reticulum|membrane|microsome|mitochondrion|nucleus	ATP binding|RNA binding|nucleotidyltransferase activity			NS(1)|breast(2)|endometrium(4)|large_intestine(7)|lung(8)|ovary(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	28						CCGCCTTCAACGCTCTGAGTA	0.493000													9	37					0	0	1	0	0
ANKMY1	51281	broad.mit.edu	37	2	241468502	241468502	+	Missense_Mutation	SNP	T	T	A			TCGA-J8-A4HW-06A-11D-A257-08	TCGA-J8-A4HW-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	cd7d1d09-5c2b-414d-9ec2-e7a7d5665671	269e9978-ced5-4398-9523-947b064a3ca8	g.chr2:241468502T>A	uc010fzd.1	-	4	1030	c.905A>T	c.(904-906)aAt>aTt	p.N302I	ANKMY1_uc002vzb.1_Intron|ANKMY1_uc002vzc.1_Intron|ANKMY1_uc002vyz.1_Missense_Mutation_p.N213I|ANKMY1_uc002vza.1_Intron|ANKMY1_uc002vzd.1_Intron|ANKMY1_uc010fze.2_Intron|ANKMY1_uc002vze.3_Intron	NM_016552	NP_057636	Q9P2S6	ANKY1_HUMAN	Homo sapiens ankyrin repeat and MYND domain containing 1 (ANKMY1), transcript variant 1, mRNA.	213							zinc ion binding			central_nervous_system(1)|endometrium(5)|large_intestine(4)|lung(14)|ovary(1)|prostate(2)|skin(1)|urinary_tract(2)	30		all_epithelial(40;2.79e-15)|Breast(86;2.41e-05)|Renal(207;0.00183)|Ovarian(221;0.0228)|all_lung(227;0.0335)|Lung NSC(271;0.106)|all_hematologic(139;0.158)|Melanoma(123;0.16)|Hepatocellular(293;0.244)		Epithelial(32;1.03e-30)|all cancers(36;4.78e-28)|OV - Ovarian serous cystadenocarcinoma(60;1.45e-14)|Kidney(56;3.04e-09)|KIRC - Kidney renal clear cell carcinoma(57;3.23e-08)|BRCA - Breast invasive adenocarcinoma(100;7.8e-06)|Lung(119;0.00271)|LUSC - Lung squamous cell carcinoma(224;0.01)|Colorectal(34;0.0101)|COAD - Colon adenocarcinoma(134;0.0476)		AGGGGTCTCATTGATTATGAA	0.512000													29	110					0	0	1	0	0
CABLES1	91768	broad.mit.edu	37	18	20774481	20774481	+	Silent	SNP	G	G	A			TCGA-J8-A4HW-06A-11D-A257-08	TCGA-J8-A4HW-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	cd7d1d09-5c2b-414d-9ec2-e7a7d5665671	269e9978-ced5-4398-9523-947b064a3ca8	g.chr18:20774481G>A	uc002kuc.2	+	2	987	c.987G>A	c.(985-987)cgG>cgA	p.R329R	CABLES1_uc002kub.2_5'UTR|CABLES1_uc002kud.2_Silent_p.R64R	NM_001100619	NP_001094089	Q8TDN4	CABL1_HUMAN	Homo sapiens Cdk5 and Abl enzyme substrate 1 (CABLES1), transcript variant 2, mRNA.	329	Interacts with CDK3 (By similarity).				blood coagulation|cell cycle|cell division|regulation of cell cycle|regulation of cell division	cytosol|nucleus	cyclin-dependent protein kinase regulator activity|protein binding			breast(1)|kidney(2)|large_intestine(1)|lung(4)|ovary(1)|prostate(1)|stomach(1)	11	all_cancers(21;0.000102)|all_epithelial(16;2.48e-06)|Lung NSC(20;0.00696)|all_lung(20;0.0197)|Colorectal(14;0.0202)|Ovarian(20;0.127)					AGAACATGCGGCAACACGATA	0.453000													3	34					0	0	1	0	0
OR5L1	219437	broad.mit.edu	37	11	55579307	55579307	+	Missense_Mutation	SNP	G	G	A	rs112907233	byFrequency	TCGA-J8-A4HW-06A-11D-A257-08	TCGA-J8-A4HW-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	cd7d1d09-5c2b-414d-9ec2-e7a7d5665671	269e9978-ced5-4398-9523-947b064a3ca8	g.chr11:55579307G>A	uc001nhw.1	+	0	365	c.365G>A	c.(364-366)cGc>cAc	p.R122H		NM_001004738	NP_001004738	Q8NGL2	OR5L1_HUMAN	Homo sapiens olfactory receptor, family 5, subfamily L, member 1 (OR5L1), mRNA.	122					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity	p.R122G(1)		NS(1)|breast(2)|central_nervous_system(2)|endometrium(2)|kidney(3)|large_intestine(4)|liver(4)|lung(36)|ovary(2)|pancreas(1)|prostate(5)|skin(9)|stomach(4)|upper_aerodigestive_tract(3)	78		all_epithelial(135;0.208)				GCCTATGACCGCTTTGTGGCC	0.522000													21	125					0	0	1	0	0
DNAH10	196385	broad.mit.edu	37	12	124332605	124332605	+	Missense_Mutation	SNP	G	G	T			TCGA-J8-A4HW-06A-11D-A257-08	TCGA-J8-A4HW-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	cd7d1d09-5c2b-414d-9ec2-e7a7d5665671	269e9978-ced5-4398-9523-947b064a3ca8	g.chr12:124332605G>T	uc001uft.4	+	31	5583	c.5558G>T	c.(5557-5559)tGt>tTt	p.C1853F		NM_207437	NP_997320	Q8IVF4	DYH10_HUMAN	Homo sapiens dynein, axonemal, heavy chain 10 (DNAH10), mRNA.	1853	AAA 1 (By similarity).				microtubule-based movement	cilium axoneme|cytoplasm|dynein complex|microtubule	ATP binding|ATPase activity|microtubule motor activity			breast(1)|central_nervous_system(1)|cervix(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(12)|lung(14)|ovary(4)|prostate(2)|skin(4)|upper_aerodigestive_tract(3)|urinary_tract(1)	52	all_neural(191;0.101)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;0.000207)|Epithelial(86;0.000556)|all cancers(50;0.00346)		GGCTTGCTCTGTGTTGTCACC	0.587000													22	111					0	0	1	0	0