Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
FSCB	84075	broad.mit.edu	37	14	44974999	44974999	+	Missense_Mutation	SNP	G	G	A			TCGA-EM-A3FQ-01A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	79133e29-ba0b-4e2f-a6d9-bf294c5144f0	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr14:44974999G>A	uc001wvn.3	-	0	1501	c.1192C>T	c.(1192-1194)Cct>Tct	p.P398S		NM_032135	NP_115511	Q5H9T9	FSCB_HUMAN	Homo sapiens fibrous sheath CABYR binding protein (FSCB), mRNA.	398	Pro-rich.					cilium				breast(4)|central_nervous_system(1)|endometrium(4)|kidney(3)|large_intestine(10)|lung(47)|ovary(2)|pancreas(1)|prostate(5)|skin(5)|stomach(2)|upper_aerodigestive_tract(4)|urinary_tract(1)	89				GBM - Glioblastoma multiforme(112;0.128)		GCTGGTAAAGGCTGTACTTCA	0.507000													9	75					0	0	1	0	0
NT5E	4907	broad.mit.edu	37	6	86195042	86195042	+	Missense_Mutation	SNP	T	T	C			TCGA-EM-A3FQ-01A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	79133e29-ba0b-4e2f-a6d9-bf294c5144f0	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr6:86195042T>C	uc003pko.4	+	3	1397	c.841T>C	c.(841-843)Tat>Cat	p.Y281H	NT5E_uc010kbr.3_Missense_Mutation_p.Y281H	NM_002526	NP_002517	P21589	5NTD_HUMAN	Homo sapiens 5'-nucleotidase, ecto (CD73) (NT5E), transcript variant 1, mRNA.	281					DNA metabolic process|purine base metabolic process|pyrimidine base metabolic process|pyrimidine nucleoside catabolic process	anchored to membrane|cytoplasm|membrane fraction|plasma membrane	5'-nucleotidase activity|nucleotide binding			breast(1)|central_nervous_system(1)|endometrium(2)|large_intestine(4)|lung(9)|ovary(3)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	25		all_cancers(76;0.000215)|Acute lymphoblastic leukemia(125;3.66e-08)|all_hematologic(105;8.61e-05)|all_epithelial(107;0.0427)		BRCA - Breast invasive adenocarcinoma(108;0.0417)	Pentoxifylline(DB00806)	AGTCCAGGCCTATGCTTTTGG	0.453000													3	83					0	0	1	0	0
MCF2L	23263	broad.mit.edu	37	13	113728878	113728878	+	Splice_Site	SNP	G	G	A			TCGA-EM-A3FQ-01A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	79133e29-ba0b-4e2f-a6d9-bf294c5144f0	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr13:113728878G>A	uc001vsu.3	+	10	1287	c.1287_splice	c.e10+1	p.G429_splice	MCF2L_uc001vsq.3_Splice_Site_p.G429_splice|MCF2L_uc010tjr.2_Splice_Site_p.G372_splice|MCF2L_uc001vsr.3_Splice_Site_p.G376_splice|MCF2L_uc001vss.4_Splice_Site_p.G370_splice|MCF2L_uc010tjs.2_Splice_Site_p.G370_splice|MCF2L_uc001vst.1_Splice_Site_p.G334_splice	NM_024979	NP_079255	O15068	MCF2L_HUMAN	Homo sapiens MCF.2 cell line derived transforming sequence-like (MCF2L), transcript variant 2, mRNA.	402					apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|plasma membrane	Rho guanyl-nucleotide exchange factor activity			kidney(1)|large_intestine(5)|ovary(1)|stomach(1)	8	all_lung(23;0.000374)|Lung NSC(43;0.0107)|Lung SC(71;0.0753)|all_neural(89;0.0804)|Hepatocellular(20;0.0877)|Medulloblastoma(90;0.163)	all_cancers(25;0.118)|all_lung(25;0.0368)|all_epithelial(44;0.0396)|Lung NSC(25;0.129)|Breast(118;0.188)				GAAATCAGGCGTAAGGCGGGG	0.642000													4	108					0	0	1	0	0
POTEE	445582	broad.mit.edu	37	2	131976198	131976198	+	Missense_Mutation	SNP	A	A	G			TCGA-EM-A3FQ-01A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	79133e29-ba0b-4e2f-a6d9-bf294c5144f0	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr2:131976198A>G	uc002tsn.2	+	0	275	c.223A>G	c.(223-225)Agt>Ggt	p.S75G	PLEKHB2_uc002tsh.2_Intron|POTEE_uc002tsk.2_5'UTR|POTEE_uc002tsl.2_5'UTR	NM_001083538	NP_001077007	Q6S8J3	POTEE_HUMAN	Homo sapiens POTE ankyrin domain family, member E (POTEE), mRNA.	75							ATP binding										CTGCAGGGGGAGTGGCAAGAG	0.587000													4	223					0	0	1	0	0
ADAMTS2	9509	broad.mit.edu	37	5	178553069	178553069	+	Missense_Mutation	SNP	A	A	T			TCGA-EM-A3FQ-01A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	79133e29-ba0b-4e2f-a6d9-bf294c5144f0	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr5:178553069A>T	uc003mjw.3	-	17	2782	c.2680T>A	c.(2680-2682)Ttc>Atc	p.F894I		NM_014244	NP_055059	O95450	ATS2_HUMAN	Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 2 (ADAMTS2), transcript variant 1, mRNA.	894	TSP type-1 2.				collagen catabolic process	proteinaceous extracellular matrix	metalloendopeptidase activity|zinc ion binding			breast(1)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(15)|lung(31)|ovary(1)|pancreas(3)|prostate(2)|skin(7)	72	all_cancers(89;0.000456)|all_epithelial(37;0.000138)|Renal(175;0.000159)|Lung NSC(126;0.00184)|all_lung(126;0.00326)	all_cancers(40;0.00604)|all_neural(177;0.00411)|Medulloblastoma(196;0.00508)|Lung NSC(249;0.0569)|all_lung(500;0.129)|all_hematologic(541;0.211)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)	GBM - Glioblastoma multiforme(465;0.0473)		GCGGCACAGAAGCCACGGTGT	0.652000													6	217					0	0	1	0	0
PFAS	5198	broad.mit.edu	37	17	8158830	8158830	+	Missense_Mutation	SNP	C	C	A			TCGA-EM-A3FQ-01A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	79133e29-ba0b-4e2f-a6d9-bf294c5144f0	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr17:8158830C>A	uc002gkr.3	+	4	536	c.395C>A	c.(394-396)cCc>cAc	p.P132H	PFAS_uc010vuv.2_Intron	NM_012393	NP_036525	O15067	PUR4_HUMAN	Homo sapiens phosphoribosylformylglycinamidine synthase (PFAS), mRNA.	132					'de novo' IMP biosynthetic process|glutamine metabolic process|purine base metabolic process	cytosol	ATP binding|phosphoribosylformylglycinamidine synthase activity|protein binding			central_nervous_system(3)|endometrium(8)|kidney(2)|large_intestine(2)|lung(9)|ovary(3)|pancreas(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(3)	35					L-Glutamic Acid(DB00142)|L-Glutamine(DB00130)	TTTGCCCACCCCCCGTCAGCT	0.567000													4	139					0	0	1	0	0
NPTX2	4885	broad.mit.edu	37	7	98254301	98254301	+	Nonsense_Mutation	SNP	C	C	G			TCGA-EM-A3FQ-01A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	79133e29-ba0b-4e2f-a6d9-bf294c5144f0	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr7:98254301C>G	uc003upl.2	+	2	888	c.711C>G	c.(709-711)taC>taG	p.Y237*		NM_002523	NP_002514	P47972	NPTX2_HUMAN	Homo sapiens neuronal pentraxin II (NPTX2), mRNA.	237	Pentaxin.				synaptic transmission	extracellular region	metal ion binding|sugar binding			breast(1)|central_nervous_system(2)|endometrium(1)|large_intestine(5)|lung(5)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	18	all_cancers(62;2.28e-09)|all_epithelial(64;4.86e-10)|Esophageal squamous(72;0.00918)|Lung NSC(181;0.0128)|all_lung(186;0.0142)		STAD - Stomach adenocarcinoma(171;0.215)			ACTACCTATACGGCAAGATCA	0.587000													4	286					0	0	1	0	0
TANC1	85461	broad.mit.edu	37	2	160080795	160080795	+	Missense_Mutation	SNP	G	G	A			TCGA-EM-A3FQ-01A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	79133e29-ba0b-4e2f-a6d9-bf294c5144f0	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr2:160080795G>A	uc002uag.3	+	22	4005	c.3731G>A	c.(3730-3732)gGg>gAg	p.G1244E	TANC1_uc010zcm.2_Missense_Mutation_p.G1236E|TANC1_uc010fom.1_Missense_Mutation_p.G1050E|TANC1_uc010fon.3_Missense_Mutation_p.G88E	NM_033394	NP_203752	Q9C0D5	TANC1_HUMAN	Homo sapiens tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 (TANC1), transcript variant 1, mRNA.	1244						cell junction|postsynaptic density|postsynaptic membrane	binding			breast(3)|central_nervous_system(4)|cervix(2)|endometrium(6)|kidney(4)|large_intestine(9)|lung(25)|ovary(7)|pancreas(1)|prostate(3)|skin(3)|stomach(2)|upper_aerodigestive_tract(6)|urinary_tract(2)	77						GACCACAGCGGGATGCGGCCC	0.592000													3	101					0	0	1	0	0
TMEM132B	114795	broad.mit.edu	37	12	126138656	126138656	+	Silent	SNP	G	G	A			TCGA-EM-A3FQ-01A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	79133e29-ba0b-4e2f-a6d9-bf294c5144f0	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr12:126138656G>A	uc001uhe.1	+	8	2645	c.2637G>A	c.(2635-2637)ccG>ccA	p.P879P	TMEM132B_uc001uhf.1_Silent_p.P391P	NM_052907	NP_443139	Q14DG7	T132B_HUMAN	Homo sapiens transmembrane protein 132B (TMEM132B), mRNA.	879						integral to membrane		p.P879L(1)		NS(1)|breast(9)|central_nervous_system(1)|cervix(1)|endometrium(7)|kidney(2)|large_intestine(11)|liver(1)|lung(45)|ovary(5)|pancreas(1)|prostate(4)|skin(15)|upper_aerodigestive_tract(3)|urinary_tract(1)	107	all_neural(191;0.101)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;0.000423)|Epithelial(86;0.00394)|all cancers(50;0.0362)		GGAAGTCACCGGACCCCAATA	0.517000													17	38					0	0	1	0	0
SALL1	6299	broad.mit.edu	37	16	51173859	51173859	+	Silent	SNP	A	A	G			TCGA-EM-A3FQ-01A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	79133e29-ba0b-4e2f-a6d9-bf294c5144f0	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr16:51173859A>G	uc021tif.1	-	1	2305	c.1983T>C	c.(1981-1983)gcT>gcC	p.A661A	SALL1_uc021tid.1_Silent_p.A661A|SALL1_uc021tie.1_Silent_p.A758A|SALL1_uc010cbv.3_Intron	NM_001127892	NP_001121364	Q9NSC2	SALL1_HUMAN	Homo sapiens sal-like 1 (Drosophila) (SALL1), transcript variant 2, mRNA.	758					adrenal gland development|branching involved in ureteric bud morphogenesis|embryonic digestive tract development|embryonic digit morphogenesis|gonad development|histone deacetylation|inductive cell-cell signaling|mesenchymal to epithelial transition involved in metanephros morphogenesis|negative regulation of transcription from RNA polymerase II promoter|olfactory bulb interneuron differentiation|olfactory bulb mitral cell layer development|olfactory nerve development|outer ear morphogenesis|pituitary gland development|positive regulation of Wnt receptor signaling pathway|positive regulation of transcription from RNA polymerase II promoter|ureteric bud invasion|ventricular septum development	chromocenter|cytoplasm|heterochromatin|nucleus	DNA binding|beta-catenin binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(4)|breast(2)|central_nervous_system(2)|endometrium(3)|kidney(5)|large_intestine(25)|lung(61)|ovary(3)|prostate(6)|skin(12)|upper_aerodigestive_tract(3)	126		all_cancers(37;0.0322)	COAD - Colon adenocarcinoma(2;0.24)			GCGGGGGCATAGCACGATGGA	0.552000													3	93					0	0	1	0	0