Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
TCP11L2	255394	broad.mit.edu	37	12	106715426	106715426	+	Missense_Mutation	SNP	G	G	C			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr12:106715426G>C	uc001tln.3	+	4	751	c.577G>C	c.(577-579)Gtg>Ctg	p.V193L	TCP11L2_uc001tll.3_Missense_Mutation_p.V193L|TCP11L2_uc001tlm.3_Missense_Mutation_p.V193L	NM_152772	NP_689985	Q8N4U5	T11L2_HUMAN	Homo sapiens t-complex 11 (mouse)-like 2 (TCP11L2), mRNA.	193										endometrium(2)|kidney(2)|large_intestine(5)|ovary(3)|prostate(1)|urinary_tract(2)	15						GTGTGCTCCCGTGCGAGATAA	0.493000													3	82					0	0	1	0	0
VWF	7450	broad.mit.edu	37	12	6204449	6204449	+	Splice_Site	SNP	G	G	T			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr12:6204449G>T	uc001qno.1	-	7	1326	c.945_splice	c.e7+1		VWF_uc001qnn.1_Intron|VWF_uc010set.1_Intron			P04275	VWF_HUMAN	Homo sapiens von Willebrand factor (VWF), mRNA.						blood coagulation, intrinsic pathway|cell-substrate adhesion|platelet activation|platelet degranulation|protein homooligomerization	Weibel-Palade body|endoplasmic reticulum|platelet alpha granule lumen|proteinaceous extracellular matrix	chaperone binding|collagen binding|glycoprotein binding|immunoglobulin binding|integrin binding|protease binding|protein N-terminus binding|protein homodimerization activity			NS(1)|breast(6)|central_nervous_system(5)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(25)|lung(41)|ovary(7)|pancreas(2)|prostate(6)|skin(15)|stomach(1)|upper_aerodigestive_tract(5)	129					Antihemophilic Factor(DB00025)	CTCATTTTTAGAGCTTCAGGC	0.423000													3	21					0	0	1	0	0
ARVCF	421	broad.mit.edu	37	22	19960732	19960732	+	Missense_Mutation	SNP	A	A	G			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr22:19960732A>G	uc002zqz.3	-	13	2618	c.2348T>C	c.(2347-2349)aTc>aCc	p.I783T	ARVCF_uc002zqy.3_Missense_Mutation_p.I299T	NM_001670	NP_001661	O00192	ARVC_HUMAN	Homo sapiens armadillo repeat gene deleted in velocardiofacial syndrome (ARVCF), mRNA.	783					cell adhesion|multicellular organismal development		protein binding			NS(1)|cervix(1)|endometrium(3)|liver(1)|lung(4)|prostate(1)|urinary_tract(2)	13	Colorectal(54;0.0993)					GATTTCGTGGATGGTGTTGAG	0.672000													6	11					0	0	1	0	0
WDR45	11152	broad.mit.edu	37	X	48933589	48933589	+	Missense_Mutation	SNP	C	C	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chrX:48933589C>A	uc004dml.1	-	6	627	c.455G>T	c.(454-456)tGc>tTc	p.C152F	WDR45_uc004dmi.3_5'Flank|WDR45_uc011mmt.2_Missense_Mutation_p.C49F|WDR45_uc004dmj.1_Missense_Mutation_p.C112F|WDR45_uc004dmk.1_Missense_Mutation_p.C151F|WDR45_uc004dmn.1_Missense_Mutation_p.C42F|WDR45_uc004dmp.1_Missense_Mutation_p.C152F	NM_007075	NP_009006	Q9Y484	WIPI4_HUMAN	Homo sapiens WD repeat domain 45 (WDR45), transcript variant 1, mRNA.	151					autophagy|response to starvation	organelle membrane	phosphatidylinositol-3,5-bisphosphate binding			NS(1)|breast(1)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(7)|ovary(1)|skin(1)	19						CAGGCTGGGGCAGAGGTCACA	0.597000													11	12					0	0	1	0	0
TBC1D24	57465	broad.mit.edu	37	16	2569368	2569368	+	Missense_Mutation	SNP	G	G	T			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr16:2569368G>T	uc002cqm.3	+	1	1230	c.1115G>T	c.(1114-1116)cGc>cTc	p.R372L	ATP6V0C_uc021tav.1_Missense_Mutation_p.A77S|ATP6V0C_uc002cqn.3_Missense_Mutation_p.A77S|AMDHD2_uc002cqp.3_5'Flank|AMDHD2_uc002cqq.3_5'Flank|AMDHD2_uc010uwc.2_5'Flank|AMDHD2_uc010uwd.2_5'Flank	NM_020705	NP_065756	Q9ULP9	TBC24_HUMAN	Homo sapiens TBC1 domain family, member 24 (TBC1D24), transcript variant 2, mRNA.	0	TLD.				neuron projection development	cytoplasm	Rab GTPase activator activity|protein binding			endometrium(2)|kidney(4)|large_intestine(3)|lung(4)	13						AGTCCTCATCGCCAACTCCCT	0.612000													3	64					0	0	1	0	0
MYH1	4619	broad.mit.edu	37	17	10402290	10402290	+	Splice_Site	SNP	C	C	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr17:10402290C>A	uc002gmo.3	-	29	4078	c.3984_splice	c.e29+1	p.K1328_splice	AK097500_uc002gml.1_Intron	NM_005963	NP_005954	P12882	MYH1_HUMAN	Homo sapiens myosin, heavy chain 1, skeletal muscle, adult (MYH1), mRNA.	1328						muscle myosin complex|myofibril|myosin filament	ATP binding|actin binding|calmodulin binding|motor activity			NS(7)|breast(4)|central_nervous_system(1)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(10)|large_intestine(22)|lung(78)|ovary(11)|pancreas(1)|prostate(3)|skin(13)|upper_aerodigestive_tract(4)|urinary_tract(5)	176						GTGGAGCTTACCTTTATCTCC	0.398000													5	56					0	0	1	0	0
SPOCK3	50859	broad.mit.edu	37	4	167810357	167810357	+	Missense_Mutation	SNP	C	C	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr4:167810357C>A	uc011cjq.1	-	4	606	c.549G>T	c.(547-549)caG>caT	p.Q183H	SPOCK3_uc021xuf.1_Missense_Mutation_p.Q174H|SPOCK3_uc011cjr.1_Missense_Mutation_p.Q54H|SPOCK3_uc003iri.1_Missense_Mutation_p.Q174H|SPOCK3_uc011cjs.1_Missense_Mutation_p.Q123H|SPOCK3_uc003irj.1_Missense_Mutation_p.Q171H|SPOCK3_uc011cjt.1_Missense_Mutation_p.Q82H|SPOCK3_uc011cjp.2_Missense_Mutation_p.Q171H|SPOCK3_uc011cju.1_Missense_Mutation_p.Q78H|SPOCK3_uc011cjv.1_Missense_Mutation_p.Q76H|SPOCK3_uc003irk.4_Missense_Mutation_p.Q171H|SPOCK3_uc011cjw.1_Non-coding_Transcript	NM_001204353	NP_001191282	Q9BQ16	TICN3_HUMAN	Homo sapiens sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 (SPOCK3), transcript variant 4, mRNA.	174	Kazal-like.				signal transduction	proteinaceous extracellular matrix	calcium ion binding|metalloendopeptidase inhibitor activity			NS(2)|breast(1)|central_nervous_system(1)|endometrium(4)|kidney(1)|large_intestine(9)|lung(13)|ovary(1)|prostate(1)|skin(4)|upper_aerodigestive_tract(1)	38	all_hematologic(180;0.221)	Prostate(90;0.0181)|Renal(120;0.0184)|Melanoma(52;0.0198)		GBM - Glioblastoma multiforme(119;0.02)		TGACTGAGATCTGTTTTCCTA	0.328000													22	33					0	0	1	0	0
IDE	3416	broad.mit.edu	37	10	94214212	94214212	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr10:94214212C>T	uc001kia.3	-	24	3125	c.3049G>A	c.(3049-3051)Gca>Aca	p.A1017T	IDE_uc010qnp.2_Missense_Mutation_p.A462T|IDE_uc001khz.3_Missense_Mutation_p.A462T	NM_004969	NP_004960	P14735	IDE_HUMAN	Homo sapiens insulin-degrading enzyme (IDE), transcript variant 1, mRNA.	1017					beta-amyloid metabolic process|bradykinin catabolic process|interspecies interaction between organisms|sex differentiation	cell surface|extracellular space|soluble fraction	ATP binding|metalloendopeptidase activity|protein homodimerization activity|signal transducer activity|zinc ion binding			breast(2)|central_nervous_system(1)|endometrium(2)|kidney(3)|large_intestine(10)|liver(1)|lung(10)|ovary(2)|urinary_tract(2)	33					Bacitracin(DB00626)|Insulin Glargine recombinant(DB00047)|Insulin Lyspro recombinant(DB00046)|Insulin recombinant(DB00030)|Insulin, porcine(DB00071)	CAGAGTTTTGCAGCCATGAAG	0.433000													4	129					0	0	1	0	0
PTPRD	5789	broad.mit.edu	37	9	8499764	8499764	+	Silent	SNP	G	G	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr9:8499764G>A	uc003zkk.3	-	24	2948	c.2205C>T	c.(2203-2205)ccC>ccT	p.P735P	PTPRD_uc003zkp.3_Intron|PTPRD_uc003zkq.3_Intron|PTPRD_uc003zkr.3_Intron|PTPRD_uc003zks.3_Intron|PTPRD_uc022bdj.1_Intron	NM_002839	NP_002830	P23468	PTPRD_HUMAN	Homo sapiens protein tyrosine phosphatase, receptor type, D (PTPRD), transcript variant 1, mRNA.	735	Fibronectin type-III 5.				transmembrane receptor protein tyrosine phosphatase signaling pathway	integral to plasma membrane	protein binding|transmembrane receptor protein tyrosine phosphatase activity	p.P735P(1)		NS(1)|breast(7)|central_nervous_system(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(22)|liver(1)|lung(83)|ovary(4)|pancreas(1)|prostate(7)|skin(19)|stomach(3)|upper_aerodigestive_tract(5)|urinary_tract(1)	168		all_cancers(3;3.38e-95)|all_epithelial(3;2.84e-91)|all_lung(3;7.3e-56)|Lung NSC(3;1.82e-52)|Renal(3;3.42e-19)|all_hematologic(3;0.000134)|all_neural(3;0.00409)|Acute lymphoblastic leukemia(23;0.0069)|Melanoma(3;0.0121)|Myeloproliferative disorder(4;0.0122)|Medulloblastoma(3;0.0144)|Lung SC(3;0.0301)|Ovarian(56;0.0694)|Hepatocellular(3;0.0824)		all cancers(1;3.38e-12)|Epithelial(1;2.12e-09)|STAD - Stomach adenocarcinoma(1;1.29e-07)|KIRC - Kidney renal clear cell carcinoma(3;5.49e-07)|Kidney(3;6.36e-07)|GBM - Glioblastoma multiforme(50;9.05e-05)|Lung(1;0.000189)|BRCA - Breast invasive adenocarcinoma(1;0.00178)|LUSC - Lung squamous cell carcinoma(1;0.0115)|LUAD - Lung adenocarcinoma(58;0.119)		TATTGGGCACGGGTGAGCGCC	0.483000										TSP Lung(15;0.13)			3	89					0	0	1	0	0
RFWD2	64326	broad.mit.edu	37	1	176054931	176054931	+	Silent	SNP	T	T	C			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr1:176054931T>C	uc001gku.1	-	9	1378	c.1122A>G	c.(1120-1122)acA>acG	p.T374T	RFWD2_uc001gkv.1_Silent_p.T350T|RFWD2_uc001gkw.1_Silent_p.T134T|RFWD2_uc009wwv.2_Silent_p.T173T|RFWD2_uc001gkt.1_Silent_p.T213T	NM_022457	NP_071902	Q8NHY2	RFWD2_HUMAN	Homo sapiens ring finger and WD repeat domain 2 (RFWD2), transcript variant 1, mRNA.	374					DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	centrosome|cytosol|focal adhesion|nuclear speck	protein binding|ubiquitin-protein ligase activity|zinc ion binding	p.T374I(1)		endometrium(1)|kidney(2)|large_intestine(5)|lung(17)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	30						GAGACATCCTTGTAGAAAAGT	0.348000													3	86					0	0	1	0	0
FILIP1	27145	broad.mit.edu	37	6	76022780	76022780	+	Missense_Mutation	SNP	G	G	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr6:76022780G>A	uc010kbe.3	-	5	3307	c.2777C>T	c.(2776-2778)gCg>gTg	p.A926V	FILIP1_uc003phy.1_Missense_Mutation_p.A923V|FILIP1_uc003phz.3_Missense_Mutation_p.A824V|FILIP1_uc003pia.3_Missense_Mutation_p.A923V|FILIP1_uc003pib.1_Missense_Mutation_p.A675V	NM_015687	NP_056502	Q7Z7B0	FLIP1_HUMAN	Homo sapiens filamin A interacting protein 1 (FILIP1), mRNA.	923										breast(3)|central_nervous_system(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(18)|liver(1)|lung(28)|ovary(1)|pancreas(1)|prostate(5)|skin(9)|upper_aerodigestive_tract(4)	80						CTCCAAAGTCGCAGTGCTGTT	0.473000													24	76					0	0	1	0	0
SEC14L4	284904	broad.mit.edu	37	22	30890948	30890948	+	Splice_Site	SNP	G	G	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr22:30890948G>A	uc003aid.2	-	6	524	c.424_splice	c.e6-1	p.L142_splice	SEC14L4_uc011akz.1_Splice_Site_p.L142_splice|SEC14L4_uc003aie.2_Splice_Site_p.L127_splice|SEC14L4_uc003aif.2_Splice_Site_p.L88_splice	NM_174977	NP_777637	Q9UDX3	S14L4_HUMAN	Homo sapiens SEC14-like 4 (S. cerevisiae) (SEC14L4), transcript variant 1, mRNA.	142	CRAL-TRIO.					integral to membrane|intracellular	lipid binding|transporter activity			breast(2)|central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(7)|lung(5)|pancreas(1)|skin(1)	21					Vitamin E(DB00163)	TTCCTGCCCAGCTGCTTGGGA	0.587000													11	34					0	0	1	0	0
UBR5	51366	broad.mit.edu	37	8	103297922	103297922	+	Missense_Mutation	SNP	G	G	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr8:103297922G>A	uc003ykr.2	-	38	5758	c.5303C>T	c.(5302-5304)gCt>gTt	p.A1768V	UBR5_uc003yks.2_Missense_Mutation_p.A1768V	NM_015902	NP_056986	O95071	UBR5_HUMAN	Homo sapiens ubiquitin protein ligase E3 component n-recognin 5 (UBR5), mRNA.	1768	Poly-Ala.				cell proliferation|positive regulation of canonical Wnt receptor signaling pathway|positive regulation of catenin import into nucleus|positive regulation of protein import into nucleus, translocation|progesterone receptor signaling pathway|protein polyubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|response to DNA damage stimulus	nucleus|soluble fraction	RNA binding|protein binding|ubiquitin-ubiquitin ligase activity|zinc ion binding			NS(1)|breast(13)|central_nervous_system(1)|cervix(1)|endometrium(7)|kidney(8)|large_intestine(19)|liver(1)|lung(51)|ovary(6)|pancreas(1)|prostate(5)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(2)	124	all_cancers(14;8e-07)|all_epithelial(15;2.18e-08)|Lung NSC(17;2.55e-05)|all_lung(17;8.85e-05)		OV - Ovarian serous cystadenocarcinoma(57;0.000442)			AGCTTCCAAAGCAGCTGCTGC	0.463000													10	49					0	0	1	0	0
SLAMF1	6504	broad.mit.edu	37	1	160607074	160607074	+	Missense_Mutation	SNP	G	G	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr1:160607074G>A	uc001fwl.4	-	1	668	c.322C>T	c.(322-324)Cgg>Tgg	p.R108W	SLAMF1_uc010pjk.2_Non-coding_Transcript|SLAMF1_uc010pjl.2_Non-coding_Transcript|SLAMF1_uc010pjm.2_Non-coding_Transcript|SLAMF1_uc001fwm.3_Missense_Mutation_p.R108W	NM_003037	NP_003028	Q13291	SLAF1_HUMAN	Homo sapiens signaling lymphocytic activation molecule family member 1 (SLAMF1), mRNA.	108					interspecies interaction between organisms|lymphocyte activation|positive regulation of cell proliferation	integral to membrane	antigen binding|transmembrane receptor activity			breast(2)|endometrium(4)|kidney(1)|large_intestine(5)|lung(10)|ovary(1)|skin(1)|upper_aerodigestive_tract(1)	25	all_cancers(52;4.94e-17)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.0175)			CTGCTTTCCCGTATCCCCAGG	0.468000													4	72					0	0	1	0	0
PCNT	5116	broad.mit.edu	37	21	47783836	47783836	+	Silent	SNP	C	C	T			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr21:47783836C>T	uc002zji.4	+	13	2703	c.2596C>T	c.(2596-2598)Ctg>Ttg	p.L866L	PCNT_uc002zjj.3_Silent_p.L748L	NM_006031	NP_006022	O95613	PCNT_HUMAN	Homo sapiens pericentrin (PCNT), mRNA.	866					G2/M transition of mitotic cell cycle|cilium assembly	cytosol|microtubule	calmodulin binding			NS(1)|breast(5)|central_nervous_system(2)|cervix(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(15)|liver(2)|lung(41)|ovary(5)|pancreas(3)|prostate(3)|skin(5)|upper_aerodigestive_tract(2)|urinary_tract(2)	104	Breast(49;0.112)					GCAGCTGATGCTGGCCCGGAG	0.677000													3	91					0	0	1	0	0
LPIN3	64900	broad.mit.edu	37	20	39984584	39984584	+	Silent	SNP	T	T	C			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-10A-01D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	b26431e2-7d3d-475e-bfdf-013f3306f45e	g.chr20:39984584T>C	uc010ggh.3	+	13	1807	c.1716T>C	c.(1714-1716)ccT>ccC	p.P572P	LPIN3_uc002xjx.3_Silent_p.P571P|LPIN3_uc010zwf.2_Non-coding_Transcript	NM_022896	NP_075047	Q9BQK8	LPIN3_HUMAN	Homo sapiens lipin 3 (LPIN3), mRNA.	571					fatty acid metabolic process	nucleus	phosphatidate phosphatase activity			breast(2)|central_nervous_system(1)|cervix(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|liver(2)|lung(7)|ovary(4)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	31		Myeloproliferative disorder(115;0.000739)				CAGACAGCCCTGTGATCCTGG	0.592000													3	64					0	0	1	0	0
TCP11L2	255394	broad.mit.edu	37	12	106715426	106715426	+	Missense_Mutation	SNP	G	G	C			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr12:106715426G>C	uc001tln.3	+	4	751	c.577G>C	c.(577-579)Gtg>Ctg	p.V193L	TCP11L2_uc001tll.3_Missense_Mutation_p.V193L|TCP11L2_uc001tlm.3_Missense_Mutation_p.V193L	NM_152772	NP_689985	Q8N4U5	T11L2_HUMAN	Homo sapiens t-complex 11 (mouse)-like 2 (TCP11L2), mRNA.	193										endometrium(2)|kidney(2)|large_intestine(5)|ovary(3)|prostate(1)|urinary_tract(2)	15						GTGTGCTCCCGTGCGAGATAA	0.493000													3	82					0	0	1	0	0
VWF	7450	broad.mit.edu	37	12	6204449	6204449	+	Splice_Site	SNP	G	G	T			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr12:6204449G>T	uc001qno.1	-	7	1326	c.945_splice	c.e7+1		VWF_uc001qnn.1_Intron|VWF_uc010set.1_Intron			P04275	VWF_HUMAN	Homo sapiens von Willebrand factor (VWF), mRNA.						blood coagulation, intrinsic pathway|cell-substrate adhesion|platelet activation|platelet degranulation|protein homooligomerization	Weibel-Palade body|endoplasmic reticulum|platelet alpha granule lumen|proteinaceous extracellular matrix	chaperone binding|collagen binding|glycoprotein binding|immunoglobulin binding|integrin binding|protease binding|protein N-terminus binding|protein homodimerization activity			NS(1)|breast(6)|central_nervous_system(5)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(25)|lung(41)|ovary(7)|pancreas(2)|prostate(6)|skin(15)|stomach(1)|upper_aerodigestive_tract(5)	129					Antihemophilic Factor(DB00025)	CTCATTTTTAGAGCTTCAGGC	0.423000													3	21					0	0	1	0	0
ARVCF	421	broad.mit.edu	37	22	19960732	19960732	+	Missense_Mutation	SNP	A	A	G			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr22:19960732A>G	uc002zqz.3	-	13	2618	c.2348T>C	c.(2347-2349)aTc>aCc	p.I783T	ARVCF_uc002zqy.3_Missense_Mutation_p.I299T	NM_001670	NP_001661	O00192	ARVC_HUMAN	Homo sapiens armadillo repeat gene deleted in velocardiofacial syndrome (ARVCF), mRNA.	783					cell adhesion|multicellular organismal development		protein binding			NS(1)|cervix(1)|endometrium(3)|liver(1)|lung(4)|prostate(1)|urinary_tract(2)	13	Colorectal(54;0.0993)					GATTTCGTGGATGGTGTTGAG	0.672000													6	11					0	0	1	0	0
WDR45	11152	broad.mit.edu	37	X	48933589	48933589	+	Missense_Mutation	SNP	C	C	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chrX:48933589C>A	uc004dml.1	-	6	627	c.455G>T	c.(454-456)tGc>tTc	p.C152F	WDR45_uc004dmi.3_5'Flank|WDR45_uc011mmt.2_Missense_Mutation_p.C49F|WDR45_uc004dmj.1_Missense_Mutation_p.C112F|WDR45_uc004dmk.1_Missense_Mutation_p.C151F|WDR45_uc004dmn.1_Missense_Mutation_p.C42F|WDR45_uc004dmp.1_Missense_Mutation_p.C152F	NM_007075	NP_009006	Q9Y484	WIPI4_HUMAN	Homo sapiens WD repeat domain 45 (WDR45), transcript variant 1, mRNA.	151					autophagy|response to starvation	organelle membrane	phosphatidylinositol-3,5-bisphosphate binding			NS(1)|breast(1)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(7)|ovary(1)|skin(1)	19						CAGGCTGGGGCAGAGGTCACA	0.597000													11	12					0	0	1	0	0
TBC1D24	57465	broad.mit.edu	37	16	2569368	2569368	+	Missense_Mutation	SNP	G	G	T			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr16:2569368G>T	uc002cqm.3	+	1	1230	c.1115G>T	c.(1114-1116)cGc>cTc	p.R372L	ATP6V0C_uc021tav.1_Missense_Mutation_p.A77S|ATP6V0C_uc002cqn.3_Missense_Mutation_p.A77S|AMDHD2_uc002cqp.3_5'Flank|AMDHD2_uc002cqq.3_5'Flank|AMDHD2_uc010uwc.2_5'Flank|AMDHD2_uc010uwd.2_5'Flank	NM_020705	NP_065756	Q9ULP9	TBC24_HUMAN	Homo sapiens TBC1 domain family, member 24 (TBC1D24), transcript variant 2, mRNA.	0	TLD.				neuron projection development	cytoplasm	Rab GTPase activator activity|protein binding			endometrium(2)|kidney(4)|large_intestine(3)|lung(4)	13						AGTCCTCATCGCCAACTCCCT	0.612000													3	64					0	0	1	0	0
MYH1	4619	broad.mit.edu	37	17	10402290	10402290	+	Splice_Site	SNP	C	C	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr17:10402290C>A	uc002gmo.3	-	29	4078	c.3984_splice	c.e29+1	p.K1328_splice	AK097500_uc002gml.1_Intron	NM_005963	NP_005954	P12882	MYH1_HUMAN	Homo sapiens myosin, heavy chain 1, skeletal muscle, adult (MYH1), mRNA.	1328						muscle myosin complex|myofibril|myosin filament	ATP binding|actin binding|calmodulin binding|motor activity			NS(7)|breast(4)|central_nervous_system(1)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(10)|large_intestine(22)|lung(78)|ovary(11)|pancreas(1)|prostate(3)|skin(13)|upper_aerodigestive_tract(4)|urinary_tract(5)	176						GTGGAGCTTACCTTTATCTCC	0.398000													5	56					0	0	1	0	0
SPOCK3	50859	broad.mit.edu	37	4	167810357	167810357	+	Missense_Mutation	SNP	C	C	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr4:167810357C>A	uc011cjq.1	-	4	606	c.549G>T	c.(547-549)caG>caT	p.Q183H	SPOCK3_uc021xuf.1_Missense_Mutation_p.Q174H|SPOCK3_uc011cjr.1_Missense_Mutation_p.Q54H|SPOCK3_uc003iri.1_Missense_Mutation_p.Q174H|SPOCK3_uc011cjs.1_Missense_Mutation_p.Q123H|SPOCK3_uc003irj.1_Missense_Mutation_p.Q171H|SPOCK3_uc011cjt.1_Missense_Mutation_p.Q82H|SPOCK3_uc011cjp.2_Missense_Mutation_p.Q171H|SPOCK3_uc011cju.1_Missense_Mutation_p.Q78H|SPOCK3_uc011cjv.1_Missense_Mutation_p.Q76H|SPOCK3_uc003irk.4_Missense_Mutation_p.Q171H|SPOCK3_uc011cjw.1_Non-coding_Transcript	NM_001204353	NP_001191282	Q9BQ16	TICN3_HUMAN	Homo sapiens sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 (SPOCK3), transcript variant 4, mRNA.	174	Kazal-like.				signal transduction	proteinaceous extracellular matrix	calcium ion binding|metalloendopeptidase inhibitor activity			NS(2)|breast(1)|central_nervous_system(1)|endometrium(4)|kidney(1)|large_intestine(9)|lung(13)|ovary(1)|prostate(1)|skin(4)|upper_aerodigestive_tract(1)	38	all_hematologic(180;0.221)	Prostate(90;0.0181)|Renal(120;0.0184)|Melanoma(52;0.0198)		GBM - Glioblastoma multiforme(119;0.02)		TGACTGAGATCTGTTTTCCTA	0.328000													22	33					0	0	1	0	0
IDE	3416	broad.mit.edu	37	10	94214212	94214212	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr10:94214212C>T	uc001kia.3	-	24	3125	c.3049G>A	c.(3049-3051)Gca>Aca	p.A1017T	IDE_uc010qnp.2_Missense_Mutation_p.A462T|IDE_uc001khz.3_Missense_Mutation_p.A462T	NM_004969	NP_004960	P14735	IDE_HUMAN	Homo sapiens insulin-degrading enzyme (IDE), transcript variant 1, mRNA.	1017					beta-amyloid metabolic process|bradykinin catabolic process|interspecies interaction between organisms|sex differentiation	cell surface|extracellular space|soluble fraction	ATP binding|metalloendopeptidase activity|protein homodimerization activity|signal transducer activity|zinc ion binding			breast(2)|central_nervous_system(1)|endometrium(2)|kidney(3)|large_intestine(10)|liver(1)|lung(10)|ovary(2)|urinary_tract(2)	33					Bacitracin(DB00626)|Insulin Glargine recombinant(DB00047)|Insulin Lyspro recombinant(DB00046)|Insulin recombinant(DB00030)|Insulin, porcine(DB00071)	CAGAGTTTTGCAGCCATGAAG	0.433000													4	129					0	0	1	0	0
PTPRD	5789	broad.mit.edu	37	9	8499764	8499764	+	Silent	SNP	G	G	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr9:8499764G>A	uc003zkk.3	-	24	2948	c.2205C>T	c.(2203-2205)ccC>ccT	p.P735P	PTPRD_uc003zkp.3_Intron|PTPRD_uc003zkq.3_Intron|PTPRD_uc003zkr.3_Intron|PTPRD_uc003zks.3_Intron|PTPRD_uc022bdj.1_Intron	NM_002839	NP_002830	P23468	PTPRD_HUMAN	Homo sapiens protein tyrosine phosphatase, receptor type, D (PTPRD), transcript variant 1, mRNA.	735	Fibronectin type-III 5.				transmembrane receptor protein tyrosine phosphatase signaling pathway	integral to plasma membrane	protein binding|transmembrane receptor protein tyrosine phosphatase activity	p.P735P(1)		NS(1)|breast(7)|central_nervous_system(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(22)|liver(1)|lung(83)|ovary(4)|pancreas(1)|prostate(7)|skin(19)|stomach(3)|upper_aerodigestive_tract(5)|urinary_tract(1)	168		all_cancers(3;3.38e-95)|all_epithelial(3;2.84e-91)|all_lung(3;7.3e-56)|Lung NSC(3;1.82e-52)|Renal(3;3.42e-19)|all_hematologic(3;0.000134)|all_neural(3;0.00409)|Acute lymphoblastic leukemia(23;0.0069)|Melanoma(3;0.0121)|Myeloproliferative disorder(4;0.0122)|Medulloblastoma(3;0.0144)|Lung SC(3;0.0301)|Ovarian(56;0.0694)|Hepatocellular(3;0.0824)		all cancers(1;3.38e-12)|Epithelial(1;2.12e-09)|STAD - Stomach adenocarcinoma(1;1.29e-07)|KIRC - Kidney renal clear cell carcinoma(3;5.49e-07)|Kidney(3;6.36e-07)|GBM - Glioblastoma multiforme(50;9.05e-05)|Lung(1;0.000189)|BRCA - Breast invasive adenocarcinoma(1;0.00178)|LUSC - Lung squamous cell carcinoma(1;0.0115)|LUAD - Lung adenocarcinoma(58;0.119)		TATTGGGCACGGGTGAGCGCC	0.483000										TSP Lung(15;0.13)			3	89					0	0	1	0	0
RFWD2	64326	broad.mit.edu	37	1	176054931	176054931	+	Silent	SNP	T	T	C			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr1:176054931T>C	uc001gku.1	-	9	1378	c.1122A>G	c.(1120-1122)acA>acG	p.T374T	RFWD2_uc001gkv.1_Silent_p.T350T|RFWD2_uc001gkw.1_Silent_p.T134T|RFWD2_uc009wwv.2_Silent_p.T173T|RFWD2_uc001gkt.1_Silent_p.T213T	NM_022457	NP_071902	Q8NHY2	RFWD2_HUMAN	Homo sapiens ring finger and WD repeat domain 2 (RFWD2), transcript variant 1, mRNA.	374					DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	centrosome|cytosol|focal adhesion|nuclear speck	protein binding|ubiquitin-protein ligase activity|zinc ion binding	p.T374I(1)		endometrium(1)|kidney(2)|large_intestine(5)|lung(17)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	30						GAGACATCCTTGTAGAAAAGT	0.348000													3	86					0	0	1	0	0
FILIP1	27145	broad.mit.edu	37	6	76022780	76022780	+	Missense_Mutation	SNP	G	G	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr6:76022780G>A	uc010kbe.3	-	5	3307	c.2777C>T	c.(2776-2778)gCg>gTg	p.A926V	FILIP1_uc003phy.1_Missense_Mutation_p.A923V|FILIP1_uc003phz.3_Missense_Mutation_p.A824V|FILIP1_uc003pia.3_Missense_Mutation_p.A923V|FILIP1_uc003pib.1_Missense_Mutation_p.A675V	NM_015687	NP_056502	Q7Z7B0	FLIP1_HUMAN	Homo sapiens filamin A interacting protein 1 (FILIP1), mRNA.	923										breast(3)|central_nervous_system(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(18)|liver(1)|lung(28)|ovary(1)|pancreas(1)|prostate(5)|skin(9)|upper_aerodigestive_tract(4)	80						CTCCAAAGTCGCAGTGCTGTT	0.473000													24	76					0	0	1	0	0
SEC14L4	284904	broad.mit.edu	37	22	30890948	30890948	+	Splice_Site	SNP	G	G	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr22:30890948G>A	uc003aid.2	-	6	524	c.424_splice	c.e6-1	p.L142_splice	SEC14L4_uc011akz.1_Splice_Site_p.L142_splice|SEC14L4_uc003aie.2_Splice_Site_p.L127_splice|SEC14L4_uc003aif.2_Splice_Site_p.L88_splice	NM_174977	NP_777637	Q9UDX3	S14L4_HUMAN	Homo sapiens SEC14-like 4 (S. cerevisiae) (SEC14L4), transcript variant 1, mRNA.	142	CRAL-TRIO.					integral to membrane|intracellular	lipid binding|transporter activity			breast(2)|central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(7)|lung(5)|pancreas(1)|skin(1)	21					Vitamin E(DB00163)	TTCCTGCCCAGCTGCTTGGGA	0.587000													11	34					0	0	1	0	0
UBR5	51366	broad.mit.edu	37	8	103297922	103297922	+	Missense_Mutation	SNP	G	G	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr8:103297922G>A	uc003ykr.2	-	38	5758	c.5303C>T	c.(5302-5304)gCt>gTt	p.A1768V	UBR5_uc003yks.2_Missense_Mutation_p.A1768V	NM_015902	NP_056986	O95071	UBR5_HUMAN	Homo sapiens ubiquitin protein ligase E3 component n-recognin 5 (UBR5), mRNA.	1768	Poly-Ala.				cell proliferation|positive regulation of canonical Wnt receptor signaling pathway|positive regulation of catenin import into nucleus|positive regulation of protein import into nucleus, translocation|progesterone receptor signaling pathway|protein polyubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|response to DNA damage stimulus	nucleus|soluble fraction	RNA binding|protein binding|ubiquitin-ubiquitin ligase activity|zinc ion binding			NS(1)|breast(13)|central_nervous_system(1)|cervix(1)|endometrium(7)|kidney(8)|large_intestine(19)|liver(1)|lung(51)|ovary(6)|pancreas(1)|prostate(5)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(2)	124	all_cancers(14;8e-07)|all_epithelial(15;2.18e-08)|Lung NSC(17;2.55e-05)|all_lung(17;8.85e-05)		OV - Ovarian serous cystadenocarcinoma(57;0.000442)			AGCTTCCAAAGCAGCTGCTGC	0.463000													10	49					0	0	1	0	0
SLAMF1	6504	broad.mit.edu	37	1	160607074	160607074	+	Missense_Mutation	SNP	G	G	A			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr1:160607074G>A	uc001fwl.4	-	1	668	c.322C>T	c.(322-324)Cgg>Tgg	p.R108W	SLAMF1_uc010pjk.2_Non-coding_Transcript|SLAMF1_uc010pjl.2_Non-coding_Transcript|SLAMF1_uc010pjm.2_Non-coding_Transcript|SLAMF1_uc001fwm.3_Missense_Mutation_p.R108W	NM_003037	NP_003028	Q13291	SLAF1_HUMAN	Homo sapiens signaling lymphocytic activation molecule family member 1 (SLAMF1), mRNA.	108					interspecies interaction between organisms|lymphocyte activation|positive regulation of cell proliferation	integral to membrane	antigen binding|transmembrane receptor activity			breast(2)|endometrium(4)|kidney(1)|large_intestine(5)|lung(10)|ovary(1)|skin(1)|upper_aerodigestive_tract(1)	25	all_cancers(52;4.94e-17)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.0175)			CTGCTTTCCCGTATCCCCAGG	0.468000													4	72					0	0	1	0	0
PCNT	5116	broad.mit.edu	37	21	47783836	47783836	+	Silent	SNP	C	C	T			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr21:47783836C>T	uc002zji.4	+	13	2703	c.2596C>T	c.(2596-2598)Ctg>Ttg	p.L866L	PCNT_uc002zjj.3_Silent_p.L748L	NM_006031	NP_006022	O95613	PCNT_HUMAN	Homo sapiens pericentrin (PCNT), mRNA.	866					G2/M transition of mitotic cell cycle|cilium assembly	cytosol|microtubule	calmodulin binding			NS(1)|breast(5)|central_nervous_system(2)|cervix(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(15)|liver(2)|lung(41)|ovary(5)|pancreas(3)|prostate(3)|skin(5)|upper_aerodigestive_tract(2)|urinary_tract(2)	104	Breast(49;0.112)					GCAGCTGATGCTGGCCCGGAG	0.677000													3	91					0	0	1	0	0
LPIN3	64900	broad.mit.edu	37	20	39984584	39984584	+	Silent	SNP	T	T	C			TCGA-BJ-A2N9-01A-11D-A18F-08	TCGA-BJ-A2N9-11A-11D-A18F-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7a00bec6-810b-4749-93e0-039659cbf4c9	bb3a19af-edb8-47af-8b53-7024b0ca12e2	g.chr20:39984584T>C	uc010ggh.3	+	13	1807	c.1716T>C	c.(1714-1716)ccT>ccC	p.P572P	LPIN3_uc002xjx.3_Silent_p.P571P|LPIN3_uc010zwf.2_Non-coding_Transcript	NM_022896	NP_075047	Q9BQK8	LPIN3_HUMAN	Homo sapiens lipin 3 (LPIN3), mRNA.	571					fatty acid metabolic process	nucleus	phosphatidate phosphatase activity			breast(2)|central_nervous_system(1)|cervix(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|liver(2)|lung(7)|ovary(4)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	31		Myeloproliferative disorder(115;0.000739)				CAGACAGCCCTGTGATCCTGG	0.592000													3	64					0	0	1	0	0