Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID Genome_Change Annotation_Transcript Transcript_Strand Transcript_Exon Transcript_Position cDNA_Change Codon_Change Protein_Change Other_Transcripts Refseq_mRNA_Id Refseq_prot_Id SwissProt_acc_Id SwissProt_entry_Id Description UniProt_AApos UniProt_Region UniProt_Site UniProt_Natural_Variations UniProt_Experimental_Info GO_Biological_Process GO_Cellular_Component GO_Molecular_Function COSMIC_overlapping_mutations COSMIC_fusion_genes COSMIC_tissue_types_affected COSMIC_total_alterations_in_gene Tumorscape_Amplification_Peaks Tumorscape_Deletion_Peaks TCGAscape_Amplification_Peaks TCGAscape_Deletion_Peaks DrugBank ref_context gc_content CCLE_ONCOMAP_overlapping_mutations CCLE_ONCOMAP_total_mutations_in_gene CGC_Mutation_Type CGC_Translocation_Partner CGC_Tumor_Types_Somatic CGC_Tumor_Types_Germline CGC_Other_Diseases DNARepairGenes_Role FamilialCancerDatabase_Syndromes MUTSIG_Published_Results OREGANNO_ID OREGANNO_Values t_alt_count t_ref_count validation_alt_allele validation_method validation_status validation_tumor_sample pox qox pox_cutoff isArtifactMode oxoGCut MIR876 100126310 broad.mit.edu 37 9 28863696 28863696 + RNA SNP A A C TCGA-BJ-A192-01A-31D-A13W-08 TCGA-BJ-A192-10A-01D-A13W-08 Untested Somatic Phase_I WXS none Illumina GAIIx 8d79a268-fa99-488e-ac9a-24e7adef76bc 05f2dae1-eff1-46b9-ada8-423cb1cdb118 g.chr9:28863696A>C uc022bfd.1 - 0 c.9T>G Homo sapiens microRNA 876 (MIR876), microRNA. AGAAATCCACAGCACTTCACA 0.403000 14 27 0 0 1 0 0 LGALS13 29124 broad.mit.edu 37 19 40095966 40095966 + Missense_Mutation SNP G G A TCGA-BJ-A192-01A-31D-A13W-08 TCGA-BJ-A192-10A-01D-A13W-08 Untested Somatic Phase_I WXS none Illumina GAIIx 8d79a268-fa99-488e-ac9a-24e7adef76bc 05f2dae1-eff1-46b9-ada8-423cb1cdb118 g.chr19:40095966G>A uc002omb.3 + 2 281 c.241G>A c.(241-243)Gtg>Atg p.V81M NM_013268 NP_037400 Q9UHV8 PP13_HUMAN Homo sapiens lectin, galactoside-binding, soluble, 13 (LGALS13), mRNA. 81 Galectin. lipid catabolic process|phospholipid metabolic process carboxylesterase activity|lysophospholipase activity|sugar binding lung(5)|ovary(1)|urinary_tract(1) 7 all_cancers(60;1.77e-05)|all_lung(34;5.38e-08)|Lung NSC(34;6.37e-08)|Ovarian(47;0.116) Epithelial(26;3.28e-26)|OV - Ovarian serous cystadenocarcinoma(5;7.31e-25)|all cancers(26;1.15e-23)|LUSC - Lung squamous cell carcinoma(53;0.00281) AACAGACTACGTGCCCTTTGA 0.493000 31 47 0 0 1 0 0 KEAP1 9817 broad.mit.edu 37 19 10600426 10600426 + Missense_Mutation SNP C C T TCGA-BJ-A192-01A-31D-A13W-08 TCGA-BJ-A192-10A-01D-A13W-08 Untested Somatic Phase_I WXS none Illumina GAIIx 8d79a268-fa99-488e-ac9a-24e7adef76bc 05f2dae1-eff1-46b9-ada8-423cb1cdb118 g.chr19:10600426C>T uc002moq.1 - 3 1585 c.1429G>A c.(1429-1431)Ggc>Agc p.G477S KEAP1_uc002mop.1_Missense_Mutation_p.G195S|KEAP1_uc002mor.1_Missense_Mutation_p.G477S NM_012289 NP_987096 Q14145 KEAP1_HUMAN Homo sapiens kelch-like ECH-associated protein 1 (KEAP1), transcript variant 2, mRNA. 477 regulation of transcription, DNA-dependent|transcription, DNA-dependent centrosome|midbody|nucleus protein binding breast(3)|endometrium(2)|kidney(4)|large_intestine(4)|liver(2)|lung(69)|ovary(2)|pancreas(1)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2) 92 OV - Ovarian serous cystadenocarcinoma(20;2.71e-09)|Epithelial(33;2.32e-06)|all cancers(31;1.42e-05) CCGTCAAAGCCCCCCACGGCA 0.577000 12 8 0 0 1 0 0 CDH12 1010 broad.mit.edu 37 5 21842341 21842341 + Missense_Mutation SNP C C T TCGA-BJ-A192-01A-31D-A13W-08 TCGA-BJ-A192-10A-01D-A13W-08 Untested Somatic Phase_I WXS none Illumina GAIIx 8d79a268-fa99-488e-ac9a-24e7adef76bc 05f2dae1-eff1-46b9-ada8-423cb1cdb118 g.chr5:21842341C>T uc010iuc.2 - 4 1201 c.743G>A c.(742-744)gGa>gAa p.G248E CDH12_uc011cno.1_Missense_Mutation_p.G208E|CDH12_uc003jgk.2_Missense_Mutation_p.G248E NM_004061 NP_004052 P55289 CAD12_HUMAN Homo sapiens cadherin 12, type 2 (N-cadherin 2) (CDH12), mRNA. 248 Cadherin 2. adherens junction organization|cell junction assembly|homophilic cell adhesion integral to membrane|plasma membrane calcium ion binding NS(2)|breast(2)|cervix(1)|endometrium(6)|kidney(4)|large_intestine(19)|lung(75)|ovary(2)|prostate(3)|skin(2)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1) 120 TCCGGCTAATCCTCCAAGCTG 0.423000 HNSCC(59;0.17) 9 163 0 0 1 0 0 ERAL1 26284 broad.mit.edu 37 17 27182067 27182067 + Silent SNP C C T TCGA-BJ-A192-01A-31D-A13W-08 TCGA-BJ-A192-10A-01D-A13W-08 Untested Somatic Phase_I WXS none Illumina GAIIx 8d79a268-fa99-488e-ac9a-24e7adef76bc 05f2dae1-eff1-46b9-ada8-423cb1cdb118 g.chr17:27182067C>T uc002hcy.1 + 0 25 c.15C>T c.(13-15)agC>agT p.S5S ERAL1_uc002hcx.1_Silent_p.S5S|ERAL1_uc002hcz.1_Non-coding_Transcript|ERAL1_uc002hda.1_5'Flank NM_005702 NP_005693 O75616 ERAL1_HUMAN Homo sapiens Era G-protein-like 1 (E. coli) (ERAL1), mRNA. 5 ribosomal small subunit assembly mitochondrial inner membrane|mitochondrial matrix GTP binding|rRNA binding|ribosomal small subunit binding endometrium(1)|kidney(1)|large_intestine(2)|lung(5)|skin(2) 11 all_cancers(5;2.12e-15)|all_epithelial(6;3.44e-19)|Lung NSC(42;0.01) Epithelial(11;1.12e-05)|all cancers(11;5.32e-05)|BRCA - Breast invasive adenocarcinoma(11;0.000272)|OV - Ovarian serous cystadenocarcinoma(11;0.105) CTGCCCCCAGCTGGCGCGGGG 0.612000 5 26 0 0 1 0 0 GNAT1 2779 broad.mit.edu 37 3 50230803 50230803 + Silent SNP C C T TCGA-BJ-A192-01A-31D-A13W-08 TCGA-BJ-A192-10A-01D-A13W-08 Untested Somatic Phase_I WXS none Illumina GAIIx 8d79a268-fa99-488e-ac9a-24e7adef76bc 05f2dae1-eff1-46b9-ada8-423cb1cdb118 g.chr3:50230803C>T uc003cym.2 + 2 371 c.255C>T c.(253-255)acC>acT p.T85T GNAT1_uc003cyl.2_Silent_p.T85T NM_144499 NP_653082 P11488 GNAT1_HUMAN Homo sapiens guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (GNAT1), transcript variant 1, mRNA. 85 G-protein signaling, coupled to cAMP nucleotide second messenger|detection of chemical stimulus involved in sensory perception of bitter taste|negative regulation of cyclic-nucleotide phosphodiesterase activity|rhodopsin mediated phototransduction|sensory perception of umami taste heterotrimeric G-protein complex|photoreceptor inner segment|photoreceptor outer segment membrane G-protein beta/gamma-subunit complex binding|G-protein-coupled receptor binding|GDP binding|GTP binding|GTPase activity|acyl binding|protein kinase binding|signal transducer activity central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(3)|lung(4)|ovary(2)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1) 17 BRCA - Breast invasive adenocarcinoma(193;0.000272)|KIRC - Kidney renal clear cell carcinoma(197;0.00544)|Kidney(197;0.00605) GCGCCATGACCACACTCAACA 0.637000 8 31 0 0 1 0 0 NFKBID 84807 broad.mit.edu 37 19 36387021 36387021 + Missense_Mutation SNP G G A TCGA-BJ-A192-01A-31D-A13W-08 TCGA-BJ-A192-10A-01D-A13W-08 Untested Somatic Phase_I WXS none Illumina GAIIx 8d79a268-fa99-488e-ac9a-24e7adef76bc 05f2dae1-eff1-46b9-ada8-423cb1cdb118 g.chr19:36387021G>A uc002oci.1 - 8 1041 c.467C>T c.(466-468)cCg>cTg p.P156L NFKBID_uc002och.1_5'UTR NM_139239 NP_640332 Q8NI38 IKBD_HUMAN Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta (NFKBID), mRNA. 156 inflammatory response nucleus breast(1)|cervix(1)|endometrium(2)|large_intestine(2)|lung(6)|ovary(1)|urinary_tract(1) 14 CGTGTGGAGCGGGGTGAGGCC 0.647000 9 75 0 0 1 0 0 ABP1 26 broad.mit.edu 37 7 150554081 150554081 + Nonsense_Mutation SNP C C T TCGA-BJ-A192-01A-31D-A13W-08 TCGA-BJ-A192-10A-01D-A13W-08 Untested Somatic Phase_I WXS none Illumina GAIIx 8d79a268-fa99-488e-ac9a-24e7adef76bc 05f2dae1-eff1-46b9-ada8-423cb1cdb118 g.chr7:150554081C>T uc003wia.1 + 1 613 c.523C>T c.(523-525)Caa>Taa p.Q175* ABP1_uc003why.1_Nonsense_Mutation_p.Q175*|ABP1_uc003whz.1_Nonsense_Mutation_p.Q175* NM_001091 NP_001082 P19801 ABP1_HUMAN Homo sapiens amiloride binding protein 1 (amine oxidase (copper-containing)) (ABP1), mRNA. 175 amine metabolic process extracellular space|peroxisome copper ion binding|diamine oxidase activity|heparin binding|histamine oxidase activity|methylputrescine oxidase activity|primary amine oxidase activity|propane-1,3-diamine oxidase activity|quinone binding NS(1)|breast(4)|endometrium(2)|kidney(4)|large_intestine(3)|lung(18)|ovary(3)|prostate(2)|skin(3)|stomach(3)|upper_aerodigestive_tract(1)|urinary_tract(1) 45 all_neural(206;0.219) OV - Ovarian serous cystadenocarcinoma(82;0.0121) UCEC - Uterine corpus endometrioid carcinoma (81;0.168) Amiloride(DB00594)|Spermine(DB00127) CTTCTCATTCCAAGACTGCCA 0.582000 40 111 0 0 1 0 0 MSI1 4440 broad.mit.edu 37 12 120805884 120805884 + Frame_Shift_Del DEL A A - TCGA-BJ-A192-01A-31D-A13W-08 TCGA-BJ-A192-10A-01D-A13W-08 Untested Somatic Phase_I WXS none Illumina GAIIx 8d79a268-fa99-488e-ac9a-24e7adef76bc 05f2dae1-eff1-46b9-ada8-423cb1cdb118 g.chr12:120805884delA uc001tye.1 - 3 258 c.194delT c.(193-195)ttcfs p.F65fs NM_002442 NP_002433 O43347 MSI1H_HUMAN Homo sapiens musashi homolog 1 (Drosophila) (MSI1), mRNA. 65 RRM 1. nervous system development cytoplasm|nucleus nucleotide binding p.F65F(1) breast(4)|central_nervous_system(2)|cervix(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(1)|lung(5)|skin(2) 19 all_neural(191;0.0804)|Medulloblastoma(191;0.0922) GAAAGTGACGAAGCCGAAACC 0.657 9 11 --- --- --- ---