Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
NPR3	4883	broad.mit.edu	37	5	32774825	32774825	+	Silent	SNP	T	T	C			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr5:32774825T>C	uc003jhv.3	+	3	1516	c.1071T>C	c.(1069-1071)ttT>ttC	p.F357F	NPR3_uc010iuo.3_Silent_p.F141F|NPR3_uc003jhw.2_Silent_p.F141F|NPR3_uc003jhu.3_Silent_p.F357F	NM_001204375	NP_001191304	P17342	ANPRC_HUMAN	Homo sapiens natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) (NPR3), transcript variant 1, mRNA.	357					osteoclast proliferation|positive regulation of urine volume|regulation of blood pressure|regulation of osteoblast proliferation|skeletal system development	integral to membrane	hormone binding|natriuretic peptide receptor activity			autonomic_ganglia(1)|central_nervous_system(1)|endometrium(2)|large_intestine(5)|lung(12)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)	24					Nesiritide(DB04899)	TTAACATGTTTGTTGAAGGAT	0.433000													6	282					0	0	1	0	0
AP4S1	11154	broad.mit.edu	37	14	31553973	31553973	+	Splice_Site	SNP	A	A	T			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr14:31553973A>T	uc001wqw.4	+	6	756	c.367_splice	c.e6-2	p.E123_splice	AP4S1_uc021rry.1_Intron|AP4S1_uc001wqx.4_Splice_Site|AP4S1_uc010amh.3_Splice_Site_p.E99_splice|AP4S1_uc001wqy.4_Intron|AP4S1_uc021rrz.1_Intron	NM_007077	NP_009008	Q9Y587	AP4S1_HUMAN	Homo sapiens adaptor-related protein complex 4, sigma 1 subunit (AP4S1), transcript variant 1, mRNA.	21						Golgi apparatus|coated pit	protein transporter activity			lung(1)	1	Hepatocellular(127;0.0877)|Breast(36;0.176)		LUAD - Lung adenocarcinoma(48;0.00292)|Lung(238;0.0164)|BRCA - Breast invasive adenocarcinoma(188;0.221)	GBM - Glioblastoma multiforme(265;0.00553)		TGTTTTTTTTAGGAACCAATT	0.413000													4	133					0	0	1	0	0
ALAD	210	broad.mit.edu	37	9	116151734	116151734	+	Missense_Mutation	SNP	C	C	A			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr9:116151734C>A	uc004bhl.4	-	9	1153	c.872G>T	c.(871-873)cGg>cTg	p.R291L	ALAD_uc011lxe.2_Missense_Mutation_p.R245L|ALAD_uc011lxf.2_Missense_Mutation_p.R262L			P13716	HEM2_HUMAN	Homo sapiens aminolevulinate dehydratase (ALAD), mRNA.	262					heme biosynthetic process|protein homooligomerization	cytosol	identical protein binding|lead ion binding|porphobilinogen synthase activity|zinc ion binding			endometrium(1)|kidney(1)|large_intestine(2)|lung(3)|prostate(1)|stomach(1)	9					Aminolevulinic acid(DB00855)	CTTTACCTCCCGCACGATGTC	0.567000													3	77					0	0	1	0	0
CLMP	79827	broad.mit.edu	37	11	122968529	122968529	+	Missense_Mutation	SNP	T	T	C			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr11:122968529T>C	uc001pyt.3	-	1	519	c.160A>G	c.(160-162)Acc>Gcc	p.T54A		NM_024769	NP_079045	Q9H6B4	CLMP_HUMAN	Homo sapiens CXADR-like membrane protein (CLMP), mRNA.	54	Ig-like C2-type 1.					integral to membrane|tight junction				endometrium(3)|large_intestine(3)|lung(6)|ovary(1)|prostate(1)	14						TCATTATCGGTGAGCAGCCAT	0.493000													4	124					0	0	1	0	0
DMD	1756	broad.mit.edu	37	X	31854884	31854884	+	Missense_Mutation	SNP	G	G	A			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chrX:31854884G>A	uc004dda.1	-	48	7395	c.7151C>T	c.(7150-7152)tCt>tTt	p.S2384F	DMD_uc004dcr.1_5'UTR|DMD_uc004dcs.1_5'UTR|DMD_uc004dct.1_5'UTR|DMD_uc004dcu.1_5'UTR|DMD_uc004dcv.1_5'UTR|DMD_uc004dcw.2_Missense_Mutation_p.S1040F|DMD_uc004dcx.2_Missense_Mutation_p.S1043F|DMD_uc004dcz.2_Missense_Mutation_p.S2261F|DMD_uc004dcy.1_Missense_Mutation_p.S2380F|DMD_uc004ddb.1_Missense_Mutation_p.S2376F|DMD_uc004ddd.1_5'UTR	NM_004006	NP_004001	P11532	DMD_HUMAN	Homo sapiens dystrophin (DMD), transcript variant Dp427m, mRNA.	2384					muscle filament sliding|peptide biosynthetic process	cell surface|costamere|cytoskeleton|cytosol|dystrophin-associated glycoprotein complex|sarcolemma	actin binding|dystroglycan binding|nitric-oxide synthase binding|protein binding|structural constituent of cytoskeleton|structural constituent of muscle|zinc ion binding			NS(2)|breast(3)|central_nervous_system(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(17)|liver(1)|lung(25)|ovary(3)|pancreas(3)|prostate(2)|skin(1)|urinary_tract(2)	77		all_cancers(2;1.22e-16)|Acute lymphoblastic leukemia(2;4.65e-06)|all_hematologic(2;0.00108)|all_epithelial(3;0.00626)|all_neural(2;0.0189)|all_lung(315;0.182)|Glioma(3;0.203)				CTGCCCTTTAGACAAAATCTC	0.408000													5	98					0	0	1	0	0
RC3H1	149041	broad.mit.edu	37	1	173934152	173934152	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr1:173934152C>T	uc010pmt.2	-	8	1528	c.1441G>A	c.(1441-1443)Ggt>Agt	p.G481S	RC3H1_uc001gju.4_Missense_Mutation_p.G481S|RC3H1_uc010pms.2_Missense_Mutation_p.G481S|RC3H1_uc001gjv.3_Missense_Mutation_p.G481S	NM_172071	NP_742068	Q5TC82	RC3H1_HUMAN	Homo sapiens ring finger and CCCH-type domains 1 (RC3H1), mRNA.	481					cytoplasmic mRNA processing body assembly|negative regulation of B cell proliferation|negative regulation of T-helper cell differentiation|negative regulation of activated T cell proliferation|negative regulation of germinal center formation|nuclear-transcribed mRNA catabolic process|regulation of T cell receptor signaling pathway|regulation of mRNA stability	cytoplasmic mRNA processing body|stress granule	mRNA 3'-UTR binding|ubiquitin-protein ligase activity|zinc ion binding			NS(1)|breast(1)|central_nervous_system(1)|endometrium(5)|kidney(2)|large_intestine(7)|lung(20)|ovary(2)|pancreas(1)|prostate(1)|skin(4)|upper_aerodigestive_tract(4)|urinary_tract(1)	50						TCCACTGCACCTTCATCTGGA	0.498000													3	121					0	0	1	0	0
AMIGO1	57463	broad.mit.edu	37	1	110050830	110050830	+	Silent	SNP	G	G	A			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr1:110050830G>A	uc001dxx.4	-	1	1087	c.705C>T	c.(703-705)caC>caT	p.H235H	AMIGO1_uc021org.1_Silent_p.H235H	NM_020703	NP_065754	Q86WK6	AMGO1_HUMAN	Homo sapiens adhesion molecule with Ig-like domain 1 (AMIGO1), mRNA.	235	LRRCT.				axonal fasciculation|heterophilic cell-cell adhesion|homophilic cell adhesion|myelination|positive regulation of axonogenesis	axon|integral to membrane				autonomic_ganglia(1)|breast(2)|endometrium(1)|large_intestine(6)|lung(3)|ovary(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	16		all_epithelial(167;2.83e-05)|all_lung(203;0.00016)|Lung NSC(277;0.000318)|Breast(1374;0.244)		Colorectal(144;0.0129)|Lung(183;0.0182)|Epithelial(280;0.046)|all cancers(265;0.0492)|READ - Rectum adenocarcinoma(129;0.0689)|LUSC - Lung squamous cell carcinoma(189;0.227)		GATACTGCCAGTGTGAAAACA	0.517000													3	83					0	0	1	0	0
APCDD1	147495	broad.mit.edu	37	18	10485461	10485461	+	Missense_Mutation	SNP	C	C	A			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr18:10485461C>A	uc002kom.4	+	3	1131	c.777C>A	c.(775-777)aaC>aaA	p.N259K		NM_153000	NP_694545	Q8J025	APCD1_HUMAN	Homo sapiens adenomatosis polyposis coli down-regulated 1 (APCDD1), mRNA.	259					Wnt receptor signaling pathway|hair follicle development|negative regulation of Wnt receptor signaling pathway	integral to plasma membrane	Wnt-protein binding			NS(1)|breast(1)|endometrium(3)|large_intestine(5)|lung(7)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	22				READ - Rectum adenocarcinoma(15;0.08)		GGCTTCAGAACCACGACCATG	0.577000													5	134					0	0	1	0	0
HIF3A	64344	broad.mit.edu	37	19	46811989	46811989	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr19:46811989C>T	uc002peh.3	+	4	549	c.518C>T	c.(517-519)aCc>aTc	p.T173I	HIF3A_uc002pef.2_Missense_Mutation_p.T173I|HIF3A_uc002peg.4_Missense_Mutation_p.T173I|HIF3A_uc010xxx.2_Non-coding_Transcript|HIF3A_uc021uwf.1_Missense_Mutation_p.T117I|HIF3A_uc002pej.2_Missense_Mutation_p.T104I|HIF3A_uc010xxy.2_Missense_Mutation_p.T104I|HIF3A_uc002pel.3_Missense_Mutation_p.T171I|HIF3A_uc010xxz.2_Missense_Mutation_p.T122I	NM_152795	NP_690008	Q9Y2N7	HIF3A_HUMAN	Homo sapiens hypoxia inducible factor 3, alpha subunit (HIF3A), transcript variant 3, mRNA.	173					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	DNA binding|signal transducer activity			breast(1)|central_nervous_system(1)|endometrium(2)|large_intestine(7)|lung(14)|prostate(1)|skin(6)|upper_aerodigestive_tract(1)	33		Ovarian(192;0.00965)|all_neural(266;0.0887)		OV - Ovarian serous cystadenocarcinoma(262;0.00204)|all cancers(93;0.0107)|GBM - Glioblastoma multiforme(486;0.0489)|Epithelial(262;0.136)		AGTACACTCACCAGCCGCGGG	0.716000													5	5					0	0	1	0	0
PLEKHA8	84725	broad.mit.edu	37	7	30118255	30118255	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr7:30118255C>T	uc003taq.3	+	13	1814	c.1412C>T	c.(1411-1413)aCc>aTc	p.T471I	PLEKHA8_uc022aba.1_Intron|PLEKHA8_uc003tan.3_Intron	NM_001197026	NP_001183955	Q96JA3	PKHA8_HUMAN	Homo sapiens pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 (PLEKHA8), transcript variant 1, mRNA.	471					protein transport	cytoplasm	glycolipid binding|glycolipid transporter activity			breast(4)|large_intestine(3)|lung(8)|ovary(1)|prostate(1)	17						GCCGCGTTAACCGTAAAGGAA	0.488000													4	87					0	0	1	0	0
RALYL	138046	broad.mit.edu	37	8	85785580	85785580	+	Missense_Mutation	SNP	C	C	G			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr8:85785580C>G	uc003yct.4	+	6	806	c.672C>G	c.(670-672)gaC>gaG	p.D224E	RALYL_uc003ycq.4_Missense_Mutation_p.D211E|RALYL_uc003ycr.4_Missense_Mutation_p.D211E|RALYL_uc003ycs.4_Missense_Mutation_p.D211E|RALYL_uc010lzy.3_Missense_Mutation_p.D200E|RALYL_uc003ycu.4_Missense_Mutation_p.D138E	NM_001100391	NP_776247	Q86SE5	RALYL_HUMAN	Homo sapiens RALY RNA binding protein-like (RALYL), transcript variant 1, mRNA.	211							RNA binding|identical protein binding|nucleotide binding			endometrium(2)|kidney(2)|large_intestine(6)|lung(13)|ovary(1)	24						CTAAAATTGACTCCTTGCTAG	0.428000													2	14					0	0	1	0	0
HIST1H4L	8368	broad.mit.edu	37	6	27841025	27841025	+	Silent	SNP	A	A	T			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr6:27841025A>T	uc003njz.3	-	0	265	c.264T>A	c.(262-264)gtT>gtA	p.V88V	HIST1H3I_uc003njy.3_5'Flank	NM_003546	NP_778224	P62805	H4_HUMAN	Homo sapiens histone cluster 1, H4l (HIST1H4L), mRNA.	88					CenH3-containing nucleosome assembly at centromere|negative regulation of megakaryocyte differentiation|phosphatidylinositol-mediated signaling|telomere maintenance	nucleoplasm|nucleosome	DNA binding|protein binding			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(2)|large_intestine(2)|lung(3)|ovary(1)|upper_aerodigestive_tract(1)	13						TGAGCGCGTAAACCACGTCCA	0.542000													36	48					0	0	1	0	0
PIK3R5	23533	broad.mit.edu	37	17	8808196	8808196	+	Missense_Mutation	SNP	T	T	C			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr17:8808196T>C	uc002glt.3	-	4	377	c.310A>G	c.(310-312)Aag>Gag	p.K104E	PIK3R5_uc010vuz.2_Missense_Mutation_p.K104E|PIK3R5_uc021tqc.1_5'UTR|PIK3R5_uc010cob.2_5'UTR|PIK3R5_uc010coa.2_5'UTR|PIK3R5_uc002glu.4_5'UTR	NM_014308	NP_001238784	Q8WYR1	PI3R5_HUMAN	Homo sapiens phosphoinositide-3-kinase, regulatory subunit 5 (PIK3R5), transcript variant 2, mRNA.	104					platelet activation	cytosol|membrane|nucleus				breast(2)|central_nervous_system(1)|endometrium(4)|kidney(2)|large_intestine(3)|lung(14)|prostate(3)|skin(4)|urinary_tract(1)	34						CTGGCTGCCTTCAGAAGGAGA	0.552000													27	50					0	0	1	0	0
ZHX3	23051	broad.mit.edu	37	20	39831621	39831621	+	Silent	SNP	T	T	G			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr20:39831621T>G	uc002xjr.1	-	3	2399	c.1936A>C	c.(1936-1938)Aga>Cga	p.R646R	ZHX3_uc002xjs.1_Silent_p.R646R|ZHX3_uc002xjt.1_Silent_p.R646R|ZHX3_uc002xju.1_Silent_p.R646R|ZHX3_uc002xjv.1_Silent_p.R646R|ZHX3_uc002xjw.1_Silent_p.R646R|ZHX3_uc010ggg.1_Silent_p.R646R	NM_015035	NP_055850	Q9H4I2	ZHX3_HUMAN	Homo sapiens zinc fingers and homeoboxes 3 (ZHX3), mRNA.	646					negative regulation of transcription, DNA-dependent	cytoplasm|nucleolus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			endometrium(2)|kidney(5)|large_intestine(8)|lung(4)|ovary(1)|pancreas(1)|prostate(2)|skin(5)|upper_aerodigestive_tract(1)|urinary_tract(2)	31		Myeloproliferative disorder(115;0.00425)				GTTTCACTTCTCAGGCGGTCC	0.493000													6	254					0	0	1	0	0
PHF21A	51317	broad.mit.edu	37	11	45959840	45959840	+	Silent	SNP	G	G	A			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr11:45959840G>A	uc001ncc.4	-	14	2097	c.1473C>T	c.(1471-1473)tgC>tgT	p.C491C	PHF21A_uc001ncb.4_Silent_p.C445C|PHF21A_uc009ykx.3_Silent_p.C445C|PHF21A_uc001nca.1_Silent_p.C227C	NM_001101802	NP_001095272	Q96BD5	PF21A_HUMAN	Homo sapiens PHD finger protein 21A (PHF21A), transcript variant 1, mRNA.	491	Required for transcriptional repression.				blood coagulation|chromatin modification|negative regulation of transcription from RNA polymerase II promoter|regulation of transcription, DNA-dependent|transcription, DNA-dependent	histone deacetylase complex	DNA binding|zinc ion binding			central_nervous_system(2)|cervix(1)|endometrium(3)|large_intestine(10)|lung(9)|skin(2)|upper_aerodigestive_tract(2)	29						TGCAAACGCTGCAAAAATCCT	0.393000													4	94					0	0	1	0	0
RBPMS	11030	broad.mit.edu	37	8	30361916	30361916	+	Silent	SNP	G	G	A			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr8:30361916G>A	uc011lba.1	+	4	1025	c.360G>A	c.(358-360)ctG>ctA	p.L120L	RBPMS_uc003xic.1_Silent_p.L120L|RBPMS_uc003xid.1_Silent_p.L120L|RBPMS_uc003xie.1_Silent_p.L120L|RBPMS_uc003xif.1_Non-coding_Transcript|RBPMS_uc003xib.3_Silent_p.L120L|RBPMS_uc010lvh.1_Silent_p.L16L	NM_006867	NP_006858	Q93062	RBPMS_HUMAN	Homo sapiens RNA binding protein with multiple splicing (RBPMS), transcript variant 4, mRNA.	120					RNA processing|positive regulation of SMAD protein import into nucleus|positive regulation of pathway-restricted SMAD protein phosphorylation|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	nucleotide binding|poly(A) RNA binding|protein binding|transcription coactivator activity			autonomic_ganglia(1)|endometrium(2)|kidney(2)|large_intestine(1)|lung(4)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)	13				KIRC - Kidney renal clear cell carcinoma(542;0.144)|Kidney(114;0.172)		GTACTCCTCTGCCCAACACTG	0.433000													12	131					0	0	1	0	0
RNF14	9604	broad.mit.edu	37	5	141364442	141364442	+	Silent	SNP	C	C	G			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr5:141364442C>G	uc003llz.3	+	7	1559	c.1311C>G	c.(1309-1311)ctC>ctG	p.L437L	RNF14_uc003lly.3_Silent_p.L437L|RNF14_uc003lma.3_Silent_p.L437L|RNF14_uc003lmb.3_Silent_p.L311L|RNF14_uc003lmc.3_Silent_p.L437L|RNF14_uc011dbg.2_Silent_p.L261L|RNF14_uc011dbh.2_Silent_p.L134L|RNF14_uc003lmd.3_Silent_p.L437L	NM_001201365	NP_001188294	Q9UBS8	RNF14_HUMAN	Homo sapiens ring finger protein 14 (RNF14), transcript variant 6, mRNA.	437	Interaction with androgen receptor.				androgen receptor signaling pathway|positive regulation of transcription, DNA-dependent|protein ubiquitination|regulation of androgen receptor signaling pathway|regulation of transcription from RNA polymerase II promoter|response to estradiol stimulus|transcription, DNA-dependent	cytoplasm|nucleus	androgen receptor binding|small conjugating protein ligase activity|transcription coactivator activity|zinc ion binding			cervix(2)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(2)|lung(3)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	15		all_hematologic(541;0.0536)|Ovarian(839;0.118)	KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)	GBM - Glioblastoma multiforme(465;0.0407)		TGGGTTCTCTCTCTAGAGCAA	0.403000													4	229					0	0	1	0	0
FOXQ1	94234	broad.mit.edu	37	6	1313344	1313344	+	Silent	SNP	G	G	T			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr6:1313344G>T	uc003mtl.4	+	0	670	c.405G>T	c.(403-405)tcG>tcT	p.S135S		NM_033260	NP_150285	Q9C009	FOXQ1_HUMAN	Homo sapiens forkhead box Q1 (FOXQ1), mRNA.	135					DNA fragmentation involved in apoptotic nuclear change|embryo development|hair follicle morphogenesis|pattern specification process|positive regulation of caspase activity|positive regulation of transcription from RNA polymerase II promoter|regulation of sequence-specific DNA binding transcription factor activity	transcription factor complex	DNA bending activity|caspase regulator activity|double-stranded DNA binding|estrogen receptor binding|promoter binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding|ubiquitin conjugating enzyme binding	p.S135L(1)		lung(1)|urinary_tract(1)	2	Ovarian(93;0.0733)	Breast(5;0.052)|all_lung(73;0.0713)|all_hematologic(90;0.0895)		OV - Ovarian serous cystadenocarcinoma(45;0.0954)|BRCA - Breast invasive adenocarcinoma(62;0.18)		TCCGCGACTCGGCGGGCGGGC	0.687000													3	18					0	0	1	0	0
SMOC1	64093	broad.mit.edu	37	14	70477484	70477484	+	Silent	SNP	G	G	A			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr14:70477484G>A	uc001xlt.2	+	7	960	c.678G>A	c.(676-678)tcG>tcA	p.S226S	SMOC1_uc001xls.2_Silent_p.S226S	NM_001034852	NP_001030024	Q9H4F8	SMOC1_HUMAN	Homo sapiens SPARC related modular calcium binding 1 (SMOC1), transcript variant 1, mRNA.	226	Thyroglobulin type-1 2.				cell differentiation|eye development|limb development|regulation of osteoblast differentiation|signal transduction	basement membrane	calcium ion binding			breast(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(10)|ovary(1)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	21				all cancers(60;0.00417)|BRCA - Breast invasive adenocarcinoma(234;0.0119)|OV - Ovarian serous cystadenocarcinoma(108;0.028)		AAGTCTATTCGTGTGACCAGG	0.527000													4	122					0	0	1	0	0
DDX51	317781	broad.mit.edu	37	12	132626093	132626093	+	Missense_Mutation	SNP	C	C	G			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr12:132626093C>G	uc001ujy.4	-	6	1093	c.1054G>C	c.(1054-1056)Gac>Cac	p.D352H	NOC4L_uc001ujz.1_5'Flank	NM_175066	NP_778236	Q8N8A6	DDX51_HUMAN	Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 (DDX51), mRNA.	352	Helicase ATP-binding.				rRNA processing	nucleolus	ATP binding|ATP-dependent helicase activity|RNA binding			endometrium(1)|lung(5)|ovary(2)|pancreas(1)|upper_aerodigestive_tract(1)	10	all_neural(191;0.0982)|Medulloblastoma(191;0.163)	all_epithelial(31;0.241)		OV - Ovarian serous cystadenocarcinoma(86;7.59e-08)|Epithelial(86;3.62e-07)|all cancers(50;2.13e-05)		TCGATGTGGTCCACCAGGCGG	0.647000													3	38					0	0	1	0	0
TBC1D16	125058	broad.mit.edu	37	17	77926612	77926612	+	Missense_Mutation	SNP	G	G	T			TCGA-BJ-A0ZC-01A-12D-A13W-08	TCGA-BJ-A0ZC-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ae01da3a-78ad-4405-a24a-bcd786b4846b	bbb6db00-380f-4352-b719-235d668bdd23	g.chr17:77926612G>T	uc002jxj.3	-	3	901	c.785C>A	c.(784-786)cCg>cAg	p.P262Q	TBC1D16_uc002jxh.3_5'Flank|TBC1D16_uc002jxi.3_5'Flank|TBC1D16_uc002jxk.1_5'Flank	NM_019020	NP_061893	Q8TBP0	TBC16_HUMAN	Homo sapiens TBC1 domain family, member 16 (TBC1D16), mRNA.	262	Ser-rich.					intracellular	Rab GTPase activator activity			NS(1)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(13)|ovary(1)|prostate(3)	28	all_neural(118;0.167)		OV - Ovarian serous cystadenocarcinoma(97;0.00739)|BRCA - Breast invasive adenocarcinoma(99;0.0819)			GGAGCTGGACGGGGGGCTGGT	0.657000													3	42					0	0	1	0	0