Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values
TAS1R3	83756	broad.mit.edu	37	1	1267882	1267882	+	Missense_Mutation	SNP	T	T	C			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr1:1267882T>C	uc010nyk.1	+	3	971	c.971T>C	c.(970-972)TTC>TCC	p.F324S		NM_152228	NP_689414	Q7RTX0	TS1R3_HUMAN	taste receptor, type 1, member 3 precursor	324	Extracellular (Potential).				detection of chemical stimulus involved in sensory perception of sweet taste|sensory perception of umami taste	plasma membrane	protein heterodimerization activity|taste receptor activity				0	all_cancers(77;0.00164)|all_epithelial(69;0.000959)|all_lung(157;0.00963)|Lung NSC(156;0.0232)|Ovarian(185;0.0634)	all_epithelial(116;9.48e-15)|all_lung(118;9.67e-07)|Lung NSC(185;5.59e-05)|Renal(390;0.00571)|Breast(487;0.0183)|Hepatocellular(190;0.0268)|Myeloproliferative disorder(586;0.028)|Ovarian(437;0.127)|Lung SC(97;0.217)		Epithelial(90;3.01e-35)|OV - Ovarian serous cystadenocarcinoma(86;3.88e-21)|Colorectal(212;0.000157)|COAD - Colon adenocarcinoma(227;0.000193)|Kidney(185;0.00229)|BRCA - Breast invasive adenocarcinoma(365;0.00251)|STAD - Stomach adenocarcinoma(132;0.00644)|KIRC - Kidney renal clear cell carcinoma(229;0.034)|Lung(427;0.146)	Aspartame(DB00168)	GTGCTTGGCTTCCTCCAGAGG	0.692000												
UBR4	23352	broad.mit.edu	37	1	19446105	19446105	+	Silent	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr1:19446105C>T	uc001bbi.2	-	70	10405	c.10401G>A	c.(10399-10401)CAG>CAA	p.Q3467Q	UBR4_uc001bbj.1_5'Flank	NM_020765	NP_065816	Q5T4S7	UBR4_HUMAN	retinoblastoma-associated factor 600	3467					interspecies interaction between organisms	cytoplasm|cytoskeleton|integral to membrane|nucleus	calmodulin binding|ubiquitin-protein ligase activity|zinc ion binding			kidney(10)|ovary(7)|breast(4)|pancreas(2)|skin(2)	25		Colorectal(325;3.46e-05)|Renal(390;0.000147)|all_lung(284;0.000328)|Lung NSC(340;0.000406)|Breast(348;0.000814)|Ovarian(437;0.00774)|Myeloproliferative disorder(586;0.0256)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00674)|BRCA - Breast invasive adenocarcinoma(304;5.43e-05)|Kidney(64;0.000337)|KIRC - Kidney renal clear cell carcinoma(64;0.00426)|STAD - Stomach adenocarcinoma(196;0.00715)|READ - Rectum adenocarcinoma(331;0.0816)		GGTCCACAAACTGGGCAGCCT	0.468000												
UBR4	23352	broad.mit.edu	37	1	19523680	19523680	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr1:19523680G>A	uc001bbi.2	-	8	977	c.973C>T	c.(973-975)CGT>TGT	p.R325C		NM_020765	NP_065816	Q5T4S7	UBR4_HUMAN	retinoblastoma-associated factor 600	325					interspecies interaction between organisms	cytoplasm|cytoskeleton|integral to membrane|nucleus	calmodulin binding|ubiquitin-protein ligase activity|zinc ion binding			kidney(10)|ovary(7)|breast(4)|pancreas(2)|skin(2)	25		Colorectal(325;3.46e-05)|Renal(390;0.000147)|all_lung(284;0.000328)|Lung NSC(340;0.000406)|Breast(348;0.000814)|Ovarian(437;0.00774)|Myeloproliferative disorder(586;0.0256)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00674)|BRCA - Breast invasive adenocarcinoma(304;5.43e-05)|Kidney(64;0.000337)|KIRC - Kidney renal clear cell carcinoma(64;0.00426)|STAD - Stomach adenocarcinoma(196;0.00715)|READ - Rectum adenocarcinoma(331;0.0816)		TCTTGTAGACGAGAAGGATTG	0.408000												
PEAR1	375033	broad.mit.edu	37	1	156883511	156883511	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr1:156883511G>A	uc001fqj.1	+	21	2788	c.2672G>A	c.(2671-2673)AGC>AAC	p.S891N	PEAR1_uc001fqk.1_Missense_Mutation_p.S516N	NM_001080471	NP_001073940	Q5VY43	PEAR1_HUMAN	platelet endothelial aggregation receptor 1	891	Pro-rich.					integral to membrane				ovary(2)|central_nervous_system(1)	3	all_hematologic(923;0.0839)|Hepatocellular(266;0.158)					CGAAGCTACAGCTATAGCTAC	0.597000												
ASTN1	460	broad.mit.edu	37	1	177001708	177001708	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr1:177001708C>T	uc001glc.2	-	3	961	c.749G>A	c.(748-750)CGC>CAC	p.R250H	ASTN1_uc001glb.1_Missense_Mutation_p.R250H|ASTN1_uc001gld.1_Missense_Mutation_p.R250H|ASTN1_uc009wwx.1_Missense_Mutation_p.R250H|ASTN1_uc001gle.3_RNA	NM_004319	NP_004310	O14525	ASTN1_HUMAN	astrotactin isoform 1	250					cell migration|neuron cell-cell adhesion	integral to membrane				ovary(6)|skin(5)|central_nervous_system(2)|large_intestine(1)|lung(1)	15						CAGATGGTGGCGCAGATCAGT	0.617000												
OR2B11	127623	broad.mit.edu	37	1	247614356	247614356	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr1:247614356G>A	uc010pyx.1	-	1	929	c.929C>T	c.(928-930)GCC>GTC	p.A310V		NM_001004492	NP_001004492	Q5JQS5	OR2BB_HUMAN	olfactory receptor, family 2, subfamily B,	310	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			upper_aerodigestive_tract(1)	1	all_cancers(71;4.51e-05)|all_epithelial(71;1.3e-05)|Breast(184;0.0149)|Ovarian(71;0.0377)|all_lung(81;0.0662)|Lung NSC(105;0.0724)	all_cancers(173;0.241)	OV - Ovarian serous cystadenocarcinoma(106;0.0188)			CCAGATCCTGGCCAGAAGTCT	0.448000												
ITGA8	8516	broad.mit.edu	37	10	15714730	15714730	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr10:15714730C>T	uc001ioc.1	-	7	695	c.695G>A	c.(694-696)AGT>AAT	p.S232N	ITGA8_uc010qcb.1_Missense_Mutation_p.S232N	NM_003638	NP_003629	P53708	ITA8_HUMAN	integrin, alpha 8 precursor	232	FG-GAP 3.|Extracellular (Potential).				cell differentiation|cell-cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|nervous system development	integrin complex	receptor activity			ovary(3)|lung(3)	6						ATCTGCAACACTGGCAGTGAT	0.443000												
PTER	9317	broad.mit.edu	37	10	16553208	16553208	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr10:16553208G>A	uc001iog.1	+	6	1210	c.1003G>A	c.(1003-1005)GAT>AAT	p.D335N	PTER_uc001ioh.1_Missense_Mutation_p.D335N|PTER_uc001ioi.1_Missense_Mutation_p.D335N|PTER_uc009xjp.1_Missense_Mutation_p.D288N	NM_030664	NP_109589	Q96BW5	PTER_HUMAN	phosphotriesterase related	335					catabolic process		hydrolase activity, acting on ester bonds|zinc ion binding			ovary(2)	2						GAATGTGCTTGATAAGATTCT	0.383000												
CUBN	8029	broad.mit.edu	37	10	16941012	16941012	+	Nonsense_Mutation	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr10:16941012G>A	uc001ioo.2	-	54	8633	c.8581C>T	c.(8581-8583)CAG>TAG	p.Q2861*	CUBN_uc009xjq.1_RNA|CUBN_uc009xjr.1_Nonsense_Mutation_p.Q217*	NM_001081	NP_001072	O60494	CUBN_HUMAN	cubilin precursor	2861	CUB 21.				cholesterol metabolic process|cobalamin transport|hormone biosynthetic process|lipoprotein metabolic process|receptor-mediated endocytosis|tissue homeostasis|vitamin D metabolic process	brush border membrane|cytosol|endosome membrane|extrinsic to external side of plasma membrane|lysosomal lumen|lysosomal membrane	calcium ion binding|cobalamin binding|protein homodimerization activity|receptor activity|transporter activity			ovary(9)|breast(4)|pancreas(2)|upper_aerodigestive_tract(1)|large_intestine(1)|central_nervous_system(1)|kidney(1)	19					Cyanocobalamin(DB00115)|Hydroxocobalamin(DB00200)	AAGCTATTCTGACATTGTCCA	0.408000												
MUC6	4588	broad.mit.edu	37	11	1016108	1016108	+	Silent	SNP	A	A	G			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr11:1016108A>G	uc001lsw.2	-	31	6744	c.6693T>C	c.(6691-6693)GTT>GTC	p.V2231V		NM_005961	NP_005952	Q6W4X9	MUC6_HUMAN	mucin 6, gastric	2231	Ser-rich.|Thr-rich.				maintenance of gastrointestinal epithelium	extracellular region	extracellular matrix structural constituent			ovary(1)	1		all_cancers(49;3.3e-08)|all_epithelial(84;5.08e-05)|Breast(177;0.000307)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.229)		all cancers(45;1.24e-24)|BRCA - Breast invasive adenocarcinoma(625;0.00031)|Lung(200;0.0576)|LUSC - Lung squamous cell carcinoma(625;0.0703)		GAGACACGGTAACAGTGGATA	0.592000												
OR51B6	390058	broad.mit.edu	37	11	5373214	5373214	+	Silent	SNP	T	T	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr11:5373214T>A	uc010qzb.1	+	1	477	c.477T>A	c.(475-477)GTT>GTA	p.V159V	HBG2_uc001mak.1_Intron|HBE1_uc001mam.1_Intron|OR51B5_uc001maq.1_Intron	NM_001004750	NP_001004750	Q9H340	O51B6_HUMAN	olfactory receptor, family 51, subfamily B,	159	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)|skin(1)	2		Medulloblastoma(188;0.0075)|all_neural(188;0.0572)|Breast(177;0.0675)		Epithelial(150;2.9e-09)|BRCA - Breast invasive adenocarcinoma(625;0.135)		CAATAGTTGTTCGCCTACACT	0.483000												
RCE1	9986	broad.mit.edu	37	11	66611449	66611449	+	Missense_Mutation	SNP	T	T	C			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr11:66611449T>C	uc001ojk.1	+	3	355	c.311T>C	c.(310-312)CTG>CCG	p.L104P	RCE1_uc001ojl.1_5'UTR	NM_005133	NP_005124	Q9Y256	FACE2_HUMAN	prenyl protein peptidase RCE1 isoform 1	104					proteolysis	endoplasmic reticulum membrane|integral to plasma membrane	metalloendopeptidase activity			ovary(1)|breast(1)	2						CTGCTCACCCTGATGGGCTTC	0.577000												
PPFIA1	8500	broad.mit.edu	37	11	70172808	70172808	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr11:70172808C>T	uc001opo.2	+	7	1012	c.814C>T	c.(814-816)CGC>TGC	p.R272C	PPFIA1_uc001opn.1_Missense_Mutation_p.R272C|PPFIA1_uc001opp.2_RNA|PPFIA1_uc001opq.1_RNA	NM_003626	NP_003617	Q13136	LIPA1_HUMAN	PTPRF interacting protein alpha 1 isoform b	272	Potential.				cell-matrix adhesion	cytoplasm	protein binding|signal transducer activity			lung(2)|ovary(1)	3			BRCA - Breast invasive adenocarcinoma(2;1.04e-44)|LUSC - Lung squamous cell carcinoma(11;1.46e-14)|STAD - Stomach adenocarcinoma(18;0.0513)			AATGAAAGAACGCCTGGCTTC	0.423000												
NPAT	4863	broad.mit.edu	37	11	108043212	108043212	+	Missense_Mutation	SNP	A	A	C			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr11:108043212A>C	uc001pjz.3	-	13	2601	c.2499T>G	c.(2497-2499)ATT>ATG	p.I833M	NPAT_uc010rvv.1_5'Flank|NPAT_uc001pka.2_Missense_Mutation_p.I628M	NM_002519	NP_002510	Q14207	NPAT_HUMAN	nuclear protein,  ataxia-telangiectasia locus	833	Required for acceleration of G1 phase.				positive regulation of transcription, DNA-dependent|regulation of transcription involved in G1/S phase of mitotic cell cycle	Cajal body	protein C-terminus binding|protein N-terminus binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|transcription corepressor activity			ovary(2)	2		all_cancers(61;2.31e-10)|all_epithelial(67;1.11e-06)|Melanoma(852;2.55e-06)|Acute lymphoblastic leukemia(157;3.95e-05)|all_hematologic(158;0.00014)|Breast(348;0.0258)|all_neural(303;0.072)		BRCA - Breast invasive adenocarcinoma(274;1.05e-05)|Epithelial(105;3.01e-05)|all cancers(92;0.000816)|Colorectal(284;0.116)		CTGAAAAAGCAATGCCATCTT	0.393000												
PLBD1	79887	broad.mit.edu	37	12	14659923	14659923	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr12:14659923C>T	uc001rcc.1	-	9	1477	c.1316G>A	c.(1315-1317)CGT>CAT	p.R439H		NM_024829	NP_079105	Q6P4A8	PLBL1_HUMAN	phospholipase B domain containing 1	439					lipid catabolic process	extracellular region	hydrolase activity				0						CCCTTGGTCACGCCGGAAAAT	0.408000												
SLC11A2	4891	broad.mit.edu	37	12	51390641	51390641	+	Missense_Mutation	SNP	T	T	C			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr12:51390641T>C	uc001rxe.3	-	9	887	c.790A>G	c.(790-792)ATC>GTC	p.I264V	SLC11A2_uc001rxd.3_Missense_Mutation_p.I113V|SLC11A2_uc001rxc.3_Missense_Mutation_p.I264V|SLC11A2_uc001rxf.2_RNA|SLC11A2_uc001rxg.1_5'Flank|SLC11A2_uc010smx.1_Missense_Mutation_p.I260V|SLC11A2_uc001rxh.1_Missense_Mutation_p.I264V|SLC11A2_uc001rxj.1_Missense_Mutation_p.I264V|SLC11A2_uc001rxi.2_Missense_Mutation_p.I264V|SLC11A2_uc001rxk.1_Missense_Mutation_p.I293V|SLC11A2_uc010smy.1_Missense_Mutation_p.I227V	NM_000617	NP_000608	P49281	NRAM2_HUMAN	solute carrier family 11 (proton-coupled	264	Helical; (Potential).				activation of caspase activity|cellular iron ion homeostasis|cellular response to oxidative stress|detection of oxygen|ferrous iron import|multicellular organismal iron ion homeostasis|response to hypoxia|response to iron ion	apical plasma membrane|basal part of cell|cell surface|cytoplasmic vesicle|early endosome|late endosome|late endosome membrane|lysosomal membrane|lysosome|nucleus|paraferritin complex|perinuclear region of cytoplasm|perinuclear region of cytoplasm|plasma membrane|recycling endosome|trans-Golgi network	cadmium ion transmembrane transporter activity|cadmium ion transmembrane transporter activity|cobalt ion transmembrane transporter activity|copper ion transmembrane transporter activity|ferrous iron transmembrane transporter activity|ferrous iron transmembrane transporter activity|lead ion transmembrane transporter activity|lead ion transmembrane transporter activity|manganese ion transmembrane transporter activity|manganese ion transmembrane transporter activity|nickel ion transmembrane transporter activity|protein binding|solute:hydrogen symporter activity|vanadium ion transmembrane transporter activity|zinc ion transmembrane transporter activity			large_intestine(1)	1						TGTGGCATGATGACAGCTCCC	0.522000												
CCNA1	8900	broad.mit.edu	37	13	37016312	37016312	+	Missense_Mutation	SNP	A	A	C			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr13:37016312A>C	uc001uvr.3	+	8	1567	c.1217A>C	c.(1216-1218)GAA>GCA	p.E406A	CCNA1_uc010teo.1_Missense_Mutation_p.E362A|CCNA1_uc010abq.2_Missense_Mutation_p.E362A|CCNA1_uc010abp.2_Missense_Mutation_p.E362A|CCNA1_uc001uvs.3_Missense_Mutation_p.E405A|CCNA1_uc010abr.2_RNA	NM_003914	NP_003905	P78396	CCNA1_HUMAN	cyclin A1 isoform a	406					cell division|G2/M transition of mitotic cell cycle|male meiosis I|mitosis|regulation of cyclin-dependent protein kinase activity|regulation of transcription involved in G1/S phase of mitotic cell cycle|spermatogenesis	cytosol|microtubule cytoskeleton|nucleoplasm	protein kinase binding			lung(2)|skin(2)|ovary(1)	5		Breast(139;0.014)|Lung SC(185;0.0548)|Prostate(109;0.174)	KIRC - Kidney renal clear cell carcinoma(5;0.119)|Kidney(79;0.169)	all cancers(112;1.91e-07)|Epithelial(112;1.22e-05)|OV - Ovarian serous cystadenocarcinoma(117;0.00623)|BRCA - Breast invasive adenocarcinoma(63;0.0119)|GBM - Glioblastoma multiforme(144;0.0242)		GATTAGCCAGAAACCCTTGCT	0.363000												
TRIM13	10206	broad.mit.edu	37	13	50586534	50586534	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr13:50586534G>A	uc001vdq.1	+	3	771	c.458G>A	c.(457-459)CGT>CAT	p.R153H	DLEU2_uc001vdn.1_Intron|DLEU2_uc001vdo.1_Intron|KCNRG_uc001vdt.2_5'Flank|KCNRG_uc001vdu.2_5'Flank|TRIM13_uc001vdp.1_Missense_Mutation_p.R156H|TRIM13_uc001vdr.1_Missense_Mutation_p.R153H|TRIM13_uc001vds.1_Missense_Mutation_p.R153H	NM_052811	NP_434698	O60858	TRI13_HUMAN	ret finger protein 2 isoform 1	153					anatomical structure morphogenesis|ER-associated protein catabolic process|positive regulation of I-kappaB kinase/NF-kappaB cascade|protein autoubiquitination	cytoplasm|endoplasmic reticulum membrane|integral to membrane	protein binding|signal transducer activity|ubiquitin-protein ligase activity|zinc ion binding			ovary(2)	2		Acute lymphoblastic leukemia(7;3.41e-06)|Lung NSC(96;3.08e-05)|Breast(56;9.7e-05)|Prostate(109;0.00174)|Hepatocellular(98;0.0207)|Myeloproliferative disorder(33;0.163)|Lung SC(185;0.187)|all_neural(104;0.19)		GBM - Glioblastoma multiforme(99;1.53e-10)|COAD - Colon adenocarcinoma(199;0.205)		GAGACCTGGCGTCGGGGAGAT	0.453000												
EDNRB	1910	broad.mit.edu	37	13	78492255	78492255	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr13:78492255C>T	uc001vko.2	-	1	712	c.454G>A	c.(454-456)GTC>ATC	p.V152I	uc001vks.2_5'Flank|EDNRB_uc001vkq.1_Missense_Mutation_p.V152I|EDNRB_uc010aez.1_Missense_Mutation_p.V152I|EDNRB_uc001vkp.1_Missense_Mutation_p.V235I|EDNRB_uc010afa.1_Missense_Mutation_p.V152I	NM_001122659	NP_001116131	P24530	EDNRB_HUMAN	endothelin receptor type B isoform 1 precursor	152	Helical; Name=2; (Potential).				activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|enteric nervous system development|enteric smooth muscle cell differentiation|macrophage chemotaxis|negative regulation of adenylate cyclase activity|negative regulation of cellular protein metabolic process|negative regulation of neuron maturation|negative regulation of transcription from RNA polymerase II promoter|vein smooth muscle contraction	integral to plasma membrane	endothelin-B receptor activity|peptide hormone binding				0		Acute lymphoblastic leukemia(28;0.0279)|Breast(118;0.037)		GBM - Glioblastoma multiforme(99;0.0933)	Bosentan(DB00559)	ATGTCAATGACGATGTGCAGC	0.507000												
KIAA1409	57578	broad.mit.edu	37	14	94173133	94173133	+	Silent	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr14:94173133G>A	uc001ybv.1	+	48	7409	c.7326G>A	c.(7324-7326)TCG>TCA	p.S2442S	KIAA1409_uc001ybs.1_Silent_p.S2420S	NM_020818	NP_065869	Q9P2D8	UNC79_HUMAN	hypothetical protein LOC57578	2597						integral to membrane				ovary(10)|skin(4)|large_intestine(3)	17		all_cancers(154;0.0354)|all_epithelial(191;0.216)		Epithelial(152;0.188)		TGCCGGGCTCGGGCCAGAGCA	0.597000												
ASB2	51676	broad.mit.edu	37	14	94405616	94405616	+	Silent	SNP	G	G	A	rs140791740		TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr14:94405616G>A	uc001ycc.1	-	6	1800	c.1311C>T	c.(1309-1311)GCC>GCT	p.A437A	ASB2_uc001ycb.1_Silent_p.A131A|ASB2_uc001ycd.2_Silent_p.A485A|ASB2_uc001yce.1_Silent_p.A383A	NM_016150	NP_057234	Q96Q27	ASB2_HUMAN	ankyrin repeat and SOCS box-containing protein	437	ANK 12.				intracellular signal transduction					ovary(1)|pancreas(1)	2		all_cancers(154;0.13)		COAD - Colon adenocarcinoma(157;0.217)|Epithelial(152;0.232)		GGCACTTCATGGCGAACATGA	0.667000												
AQR	9716	broad.mit.edu	37	15	35196621	35196621	+	Silent	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr15:35196621G>A	uc001ziv.2	-	19	2098	c.1917C>T	c.(1915-1917)ACC>ACT	p.T639T		NM_014691	NP_055506	O60306	AQR_HUMAN	aquarius	639						catalytic step 2 spliceosome	RNA binding			large_intestine(1)	1		Lung NSC(122;8.7e-10)|all_lung(180;1.47e-08)		all cancers(64;4.34e-18)|GBM - Glioblastoma multiforme(113;4.59e-07)|BRCA - Breast invasive adenocarcinoma(123;0.0283)		GTATAGTATTGGTCATATCTT	0.353000												
UNC45B	146862	broad.mit.edu	37	17	33495164	33495164	+	Silent	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr17:33495164G>A	uc002hja.2	+	10	1333	c.1236G>A	c.(1234-1236)CTG>CTA	p.L412L	UNC45B_uc002hjb.2_Silent_p.L412L|UNC45B_uc002hjc.2_Silent_p.L412L|UNC45B_uc010cto.2_Silent_p.L412L	NM_173167	NP_775259	Q8IWX7	UN45B_HUMAN	cardiomyopathy associated 4 isoform 1	412					cell differentiation|muscle organ development	cytosol	binding			ovary(3)|central_nervous_system(2)|breast(1)	6		Ovarian(249;0.17)				CCTTTGACCTGGGCAACCAGC	0.572000												
DNAI2	64446	broad.mit.edu	37	17	72295860	72295860	+	Missense_Mutation	SNP	G	G	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr17:72295860G>T	uc002jkf.2	+	7	827	c.728G>T	c.(727-729)TGC>TTC	p.C243F	DNAI2_uc002jkg.2_RNA|DNAI2_uc010dfp.2_RNA	NM_023036	NP_075462	Q9GZS0	DNAI2_HUMAN	dynein, axonemal, intermediate polypeptide 2	243	WD 2.				cilium assembly	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	microtubule motor activity			ovary(2)|central_nervous_system(1)	3						TCACCAGCCTGCTGGGACACC	0.612000									Kartagener_syndrome			
DUS1L	64118	broad.mit.edu	37	17	80019108	80019108	+	Silent	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr17:80019108G>A	uc002kdq.2	-	7	1238	c.819C>T	c.(817-819)CAC>CAT	p.H273H	DUS1L_uc002kdp.2_Silent_p.H142H|DUS1L_uc002kdr.2_Silent_p.H273H|DUS1L_uc002kds.2_RNA|DUS1L_uc002kdt.2_RNA|DUS1L_uc010wvi.1_Silent_p.H256H	NM_022156	NP_071439	Q6P1R4	DUS1L_HUMAN	PP3111 protein	273					tRNA processing		flavin adenine dinucleotide binding|tRNA dihydrouridine synthase activity			skin(1)	1	all_neural(118;0.0878)|Ovarian(332;0.227)|all_lung(278;0.246)		BRCA - Breast invasive adenocarcinoma(99;0.0114)|OV - Ovarian serous cystadenocarcinoma(97;0.0211)			GCTTGAAGAGGTGGGCCCGGA	0.667000												
SYT4	6860	broad.mit.edu	37	18	40850588	40850588	+	Silent	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr18:40850588G>A	uc002law.2	-	4	1365	c.996C>T	c.(994-996)TAC>TAT	p.Y332Y	SYT4_uc010dng.2_RNA|SYT4_uc010xcm.1_Silent_p.Y314Y|SYT4_uc010dnh.2_Intron	NM_020783	NP_065834	Q9H2B2	SYT4_HUMAN	synaptotagmin IV	332	C2 2.|Cytoplasmic (Potential).					cell junction|integral to membrane|synaptic vesicle membrane	transporter activity			skin(5)	5						TTTTGGCATGGTACAGGTTCA	0.433000												
ACTL9	284382	broad.mit.edu	37	19	8808873	8808873	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr19:8808873G>A	uc002mkl.2	-	1	300	c.179C>T	c.(178-180)ACC>ATC	p.T60I		NM_178525	NP_848620	Q8TC94	ACTL9_HUMAN	actin-like 9	60						cytoplasm|cytoskeleton				large_intestine(2)|pancreas(1)	3						TACCTTACAGGTGCCTGTGCC	0.652000												
FCHO1	23149	broad.mit.edu	37	19	17883497	17883497	+	Missense_Mutation	SNP	A	A	G			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr19:17883497A>G	uc010ebb.2	+	10	926	c.737A>G	c.(736-738)GAG>GGG	p.E246G	FCHO1_uc002nhg.3_Missense_Mutation_p.E246G|FCHO1_uc002nhh.2_Missense_Mutation_p.E246G|FCHO1_uc010xpw.1_Missense_Mutation_p.E196G|FCHO1_uc010ebc.1_Missense_Mutation_p.E253G	NM_001161358	NP_001154830	O14526	FCHO1_HUMAN	FCH domain only 1 isoform b	246										breast(1)	1						GTCAGCGTGGAGATGCTACTC	0.607000												
DPP10	57628	broad.mit.edu	37	2	116572421	116572421	+	Missense_Mutation	SNP	G	G	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr2:116572421G>T	uc002tla.1	+	20	2210	c.1753G>T	c.(1753-1755)GAT>TAT	p.D585Y	DPP10_uc002tlb.1_Missense_Mutation_p.D535Y|DPP10_uc002tlc.1_Missense_Mutation_p.D581Y|DPP10_uc002tle.2_Missense_Mutation_p.D589Y|DPP10_uc002tlf.1_Missense_Mutation_p.D578Y	NM_020868	NP_065919	Q8N608	DPP10_HUMAN	dipeptidyl peptidase 10 isoform long	585	Extracellular (Potential).				proteolysis	integral to membrane|membrane fraction	serine-type peptidase activity			ovary(5)|large_intestine(2)|skin(2)|breast(1)	10						TATTGACTGGGATTCCGTACT	0.423000												
ZAK	51776	broad.mit.edu	37	2	174074513	174074513	+	Silent	SNP	G	G	A	rs145549000		TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr2:174074513G>A	uc002uhz.2	+	10	1001	c.801G>A	c.(799-801)ACG>ACA	p.T267T	ZAK_uc002uhx.2_Silent_p.T267T|ZAK_uc002uhy.2_Silent_p.T267T|ZAK_uc010zei.1_Silent_p.T166T|ZAK_uc002uia.1_Silent_p.T267T|uc002uib.2_RNA	NM_016653	NP_057737	Q9NYL2	MLTK_HUMAN	MLK-related kinase isoform 1	267	Protein kinase.				activation of JUN kinase activity|activation of MAPKK activity|cell cycle arrest|cell death|cell differentiation|cell proliferation|DNA damage checkpoint|positive regulation of apoptosis|response to radiation	cytoplasm|nucleus	ATP binding|identical protein binding|magnesium ion binding|MAP kinase kinase kinase activity|protein binding			lung(3)|stomach(1)|ovary(1)|skin(1)	6			OV - Ovarian serous cystadenocarcinoma(117;0.176)			CAAATGACACGAGCCTTCCTG	0.468000												
BARD1	580	broad.mit.edu	37	2	215646142	215646142	+	Silent	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr2:215646142C>T	uc002veu.2	-	4	591	c.456G>A	c.(454-456)AAG>AAA	p.K152K	BARD1_uc010zjm.1_Silent_p.K8K	NM_000465	NP_000456	Q99728	BARD1_HUMAN	BRCA1 associated RING domain 1	152					cell cycle arrest|DNA repair|negative regulation of apoptosis|negative regulation of mRNA 3'-end processing|negative regulation of protein export from nucleus|positive regulation of apoptosis|positive regulation of protein catabolic process|protein K6-linked ubiquitination|regulation of phosphorylation|tissue homeostasis	BRCA1-A complex|BRCA1-BARD1 complex|cytoplasm	kinase binding|protein heterodimerization activity|protein homodimerization activity|RNA binding|ubiquitin-protein ligase activity|zinc ion binding			lung(2)	2		Renal(323;0.0243)		Epithelial(149;3.2e-06)|all cancers(144;0.000461)|LUSC - Lung squamous cell carcinoma(224;0.00829)|Lung(261;0.011)		ATCTGACTTTCTTACTTCGAG	0.358000									Neuroblastoma_Familial_Clustering_of|Congenital_Central_Hypoventilation_Syndrome			
TTLL4	9654	broad.mit.edu	37	2	219609922	219609922	+	Silent	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr2:219609922C>T	uc002viy.2	+	6	2122	c.1752C>T	c.(1750-1752)CCC>CCT	p.P584P	TTLL4_uc010zkl.1_Silent_p.P419P|TTLL4_uc010fvx.2_Silent_p.P584P|TTLL4_uc010zkm.1_5'Flank	NM_014640	NP_055455	Q14679	TTLL4_HUMAN	tubulin tyrosine ligase-like family, member 4	584					protein polyglutamylation	cilium|microtubule basal body	ATP binding|tubulin binding|tubulin-tyrosine ligase activity			ovary(2)|skin(1)	3		Renal(207;0.0915)		Epithelial(149;5.03e-07)|all cancers(144;0.000106)|LUSC - Lung squamous cell carcinoma(224;0.00829)|Lung(261;0.0101)		CCAACGTTCCCCCTACCATCT	0.502000												
POFUT1	23509	broad.mit.edu	37	20	30818669	30818669	+	Missense_Mutation	SNP	C	C	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr20:30818669C>A	uc002wxp.2	+	6	832	c.783C>A	c.(781-783)TTC>TTA	p.F261L	POFUT1_uc010ztt.1_Missense_Mutation_p.F153L|POFUT1_uc010ztu.1_Missense_Mutation_p.F50L	NM_015352	NP_056167	Q9H488	OFUT1_HUMAN	protein O-fucosyltransferase 1 isoform 1	261					fucose metabolic process|Notch signaling pathway|O-glycan processing|regulation of transcription, DNA-dependent	endoplasmic reticulum|membrane	peptide-O-fucosyltransferase activity			breast(1)	1			UCEC - Uterine corpus endometrioid carcinoma (5;0.0241)			GCTCGCACTTCATGGCCTCTC	0.612000												
C20orf195	79025	broad.mit.edu	37	20	62187890	62187890	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr20:62187890G>A	uc002yfj.2	+	2	966	c.874G>A	c.(874-876)GTG>ATG	p.V292M	C20orf195_uc002yfk.2_Missense_Mutation_p.V292M	NM_024059	NP_076964	Q9BVV2	CT195_HUMAN	hypothetical protein LOC79025	292											0	all_cancers(38;2.51e-11)|all_epithelial(29;8.27e-13)		Epithelial(9;9.69e-09)|all cancers(9;5.84e-08)|BRCA - Breast invasive adenocarcinoma(10;3.63e-06)			CTCCACGCTGGTGTACGAGCC	0.612000												
RBMS3	27303	broad.mit.edu	37	3	29781274	29781274	+	Missense_Mutation	SNP	G	G	C			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr3:29781274G>C	uc003cel.2	+	5	693	c.463G>C	c.(463-465)GAG>CAG	p.E155Q	RBMS3_uc003cek.2_Missense_Mutation_p.E155Q|RBMS3_uc010hfq.2_Missense_Mutation_p.E155Q|RBMS3_uc003cem.2_Missense_Mutation_p.E154Q|RBMS3_uc010hfr.2_Missense_Mutation_p.E155Q	NM_001003793	NP_001003793	Q6XE24	RBMS3_HUMAN	RNA binding motif, single stranded interacting	155	RRM 2.					cytoplasm	nucleotide binding|RNA binding			central_nervous_system(1)	1		Ovarian(412;0.0956)				GGATGAGCAGGAGCTTGAGAA	0.418000												
ZBTB11	27107	broad.mit.edu	37	3	101384055	101384055	+	Missense_Mutation	SNP	T	T	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr3:101384055T>A	uc003dve.3	-	4	1606	c.1376A>T	c.(1375-1377)GAT>GTT	p.D459V		NM_014415	NP_055230	O95625	ZBT11_HUMAN	zinc finger protein ZNF-U69274	459					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			skin(1)	1						AGCTGATATATCATTTCCCAT	0.363000												
ATR	545	broad.mit.edu	37	3	142215233	142215233	+	Silent	SNP	G	G	A	rs112018640	byFrequency	TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr3:142215233G>A	uc003eux.3	-	34	5990	c.5868C>T	c.(5866-5868)TAC>TAT	p.Y1956Y		NM_001184	NP_001175	Q13535	ATR_HUMAN	ataxia telangiectasia and Rad3 related protein	1956	FAT.				cell cycle|cellular response to gamma radiation|cellular response to UV|DNA damage checkpoint|DNA repair|DNA replication|multicellular organismal development|negative regulation of DNA replication|peptidyl-serine phosphorylation|positive regulation of DNA damage response, signal transduction by p53 class mediator|protein autophosphorylation|replicative senescence	PML body	ATP binding|DNA binding|MutLalpha complex binding|MutSalpha complex binding|protein serine/threonine kinase activity	p.Y1956Y(2)		lung(5)|skin(5)|breast(4)|ovary(3)|stomach(1)|central_nervous_system(1)|liver(1)	20						CCCTTTCCACGTACAGTTCAG	0.418000								Other_conserved_DNA_damage_response_genes				
DEFB131	644414	broad.mit.edu	37	4	9452104	9452104	+	Missense_Mutation	SNP	A	A	G			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr4:9452104A>G	uc011bwt.1	+	2	77	c.77A>G	c.(76-78)AAT>AGT	p.N26S		NM_001040448	NP_001035538	P59861	DB131_HUMAN	defensin, beta 131 precursor	26					defense response to bacterium	extracellular region					0						TTCATTTCTAATGATGAATGT	0.308000												
JARID2	3720	broad.mit.edu	37	6	15512493	15512493	+	Missense_Mutation	SNP	C	C	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr6:15512493C>A	uc003nbj.2	+	14	3251	c.3007C>A	c.(3007-3009)CAG>AAG	p.Q1003K	JARID2_uc011div.1_Missense_Mutation_p.Q831K	NM_004973	NP_004964	Q92833	JARD2_HUMAN	jumonji, AT rich interactive domain 2 protein	1003	JmjC.				central nervous system development|chromatin modification|negative regulation of histone methylation|positive regulation of histone H3-K9 methylation|stem cell differentiation|transcription, DNA-dependent		chromatin binding			ovary(2)|lung(1)|pancreas(1)	4	Breast(50;0.0142)|Ovarian(93;0.103)	all_hematologic(90;0.00612)				GACCGTGCAGCAGAGTGGCCA	0.612000												
VARS2	57176	broad.mit.edu	37	6	30890739	30890739	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr6:30890739C>T	uc003nsc.1	+	22	2803	c.2171C>T	c.(2170-2172)TCC>TTC	p.S724F	VARS2_uc011dmx.1_Missense_Mutation_p.S724F|VARS2_uc011dmy.1_Missense_Mutation_p.S584F|VARS2_uc011dmz.1_Missense_Mutation_p.S754F|VARS2_uc011dna.1_Missense_Mutation_p.S722F|VARS2_uc011dnb.1_RNA|VARS2_uc011dnc.1_RNA|VARS2_uc011dnd.1_Missense_Mutation_p.S162F|VARS2_uc010jsg.1_Missense_Mutation_p.S96F|VARS2_uc010jsh.1_5'Flank	NM_020442	NP_065175	Q5ST30	SYVM_HUMAN	valyl-tRNA synthetase 2, mitochondrial	724					valyl-tRNA aminoacylation	mitochondrion	ATP binding|valine-tRNA ligase activity			ovary(3)|central_nervous_system(1)	4						ACACTCTGCTCCCATGGAGTT	0.612000												
FYN	2534	broad.mit.edu	37	6	112029214	112029214	+	Silent	SNP	A	A	G			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr6:112029214A>G	uc003pvj.2	-	5	694	c.354T>C	c.(352-354)GAT>GAC	p.D118D	FYN_uc003pvi.2_Silent_p.D118D|FYN_uc003pvk.2_Silent_p.D118D|FYN_uc003pvh.2_Silent_p.D118D	NM_002037	NP_002028	P06241	FYN_HUMAN	protein-tyrosine kinase fyn isoform a	118	SH3.				axon guidance|calcium ion transport|feeding behavior|interspecies interaction between organisms|intracellular protein kinase cascade|learning|leukocyte migration|platelet activation|regulation of defense response to virus by virus|T cell costimulation|T cell receptor signaling pathway|viral reproduction	cytosol|endosome|plasma membrane	ATP binding|glycoprotein binding|identical protein binding|metal ion binding|non-membrane spanning protein tyrosine kinase activity			lung(5)|central_nervous_system(1)|skin(1)	7		all_cancers(87;1.37e-05)|Acute lymphoblastic leukemia(125;2.15e-07)|all_hematologic(75;5.28e-06)|all_epithelial(87;0.00125)|Colorectal(196;0.0211)		all cancers(137;0.0451)|OV - Ovarian serous cystadenocarcinoma(136;0.0476)|Epithelial(106;0.102)	Dasatinib(DB01254)	CTTCCCACCAATCTCCTTCCC	0.428000												
DNAH11	8701	broad.mit.edu	37	7	21939016	21939016	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr7:21939016C>T	uc003svc.2	+	81	13164	c.13133C>T	c.(13132-13134)CCG>CTG	p.P4378L		NM_003777	NP_003768	Q96DT5	DYH11_HUMAN	dynein, axonemal, heavy chain 11	4378					microtubule-based movement	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity			ovary(8)|large_intestine(3)|pancreas(3)|central_nervous_system(1)	15						CTTACCCTTCCGGCTGTCGTG	0.537000									Kartagener_syndrome			
DDC	1644	broad.mit.edu	37	7	50607687	50607687	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr7:50607687G>A	uc003tpf.3	-	3	327	c.241C>T	c.(241-243)CCC>TCC	p.P81S	DDC_uc010kza.2_Missense_Mutation_p.P81S|DDC_uc003tpg.3_Missense_Mutation_p.P81S	NM_000790	NP_000781	P20711	DDC_HUMAN	dopa decarboxylase (aromatic L-amino acid	81	1.|2 X approximate tandem repeats.				cellular amino acid metabolic process|hormone biosynthetic process|neurotransmitter secretion	cytosol	aromatic-L-amino-acid decarboxylase activity|protein binding|pyridoxal phosphate binding			ovary(2)	2	Glioma(55;0.08)|all_neural(89;0.245)				Amantadine(DB00915)|Carbidopa(DB00190)|Flupenthixol(DB00875)|L-Tryptophan(DB00150)|Levodopa(DB01235)|Pimozide(DB01100)|Pyridoxal Phosphate(DB00114)|Remoxipride(DB00409)	CTGGCAGTGGGGAAGTAGGCG	0.637000												
MAGI2	9863	broad.mit.edu	37	7	78256458	78256458	+	Silent	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr7:78256458G>A	uc003ugx.2	-	3	770	c.516C>T	c.(514-516)CTC>CTT	p.L172L	MAGI2_uc003ugy.2_Silent_p.L172L|MAGI2_uc011kgr.1_5'UTR|MAGI2_uc011kgs.1_Silent_p.L9L	NM_012301	NP_036433	Q86UL8	MAGI2_HUMAN	membrane associated guanylate kinase, WW and PDZ	172	Guanylate kinase-like.					cell junction|synapse|synaptosome	phosphatase binding			ovary(5)|lung(4)|breast(1)|skin(1)	11		all_cancers(73;0.0064)|all_epithelial(88;0.087)|all_neural(109;0.0936)|Medulloblastoma(109;0.166)|Melanoma(862;0.236)				CACTTTCTAGGAGAGCACCAC	0.443000												
PCLO	27445	broad.mit.edu	37	7	82579972	82579972	+	Missense_Mutation	SNP	T	T	G			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr7:82579972T>G	uc003uhx.2	-	6	10221	c.9932A>C	c.(9931-9933)AAG>ACG	p.K3311T	PCLO_uc003uhv.2_Missense_Mutation_p.K3311T|PCLO_uc010lec.2_Missense_Mutation_p.K276T	NM_033026	NP_149015	Q9Y6V0	PCLO_HUMAN	piccolo isoform 1	3242	Gln-rich.				cytoskeleton organization|synaptic vesicle exocytosis	cell junction|cytoskeleton|synaptic vesicle	calcium ion binding|calcium-dependent phospholipid binding|profilin binding|transporter activity			ovary(7)	7						CTGCCGAATCTTTTGCTCCTC	0.488000												
SLC25A40	55972	broad.mit.edu	37	7	87477182	87477182	+	Missense_Mutation	SNP	C	C	G			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr7:87477182C>G	uc003uje.2	-	7	794	c.443G>C	c.(442-444)GGA>GCA	p.G148A		NM_018843	NP_061331	Q8TBP6	S2540_HUMAN	mitochondrial carrier family protein	148	Helical; Name=3; (Potential).|Solcar 2.				transmembrane transport	integral to membrane|mitochondrial inner membrane	binding			haematopoietic_and_lymphoid_tissue(1)	1	Esophageal squamous(14;0.00202)					GGCTACAATTCCAGCAACAAT	0.318000												
C7orf63	79846	broad.mit.edu	37	7	89938590	89938590	+	Missense_Mutation	SNP	T	T	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr7:89938590T>A	uc010lep.2	+	22	2815	c.2564T>A	c.(2563-2565)CTT>CAT	p.L855H	C7orf63_uc011khj.1_Missense_Mutation_p.L837H|C7orf63_uc011khk.1_Missense_Mutation_p.L371H	NM_001039706	NP_001034795	A5D8W1	CG063_HUMAN	hypothetical protein LOC79846 isoform 1	855							binding			ovary(1)	1						GCAAAAAGCCTTCAAGAAAAA	0.299000												
ZKSCAN5	23660	broad.mit.edu	37	7	99117466	99117466	+	Silent	SNP	A	A	G			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr7:99117466A>G	uc003uqv.2	+	4	694	c.570A>G	c.(568-570)CAA>CAG	p.Q190Q	ZKSCAN5_uc010lfx.2_Silent_p.Q190Q|ZKSCAN5_uc003uqw.2_Silent_p.Q190Q|ZKSCAN5_uc003uqx.2_Intron|ZKSCAN5_uc003uqy.2_5'UTR	NM_145102	NP_659570	Q9Y2L8	ZKSC5_HUMAN	zinc finger with KRAB and SCAN domains 5	190					viral reproduction	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(1)	1	all_cancers(62;2.54e-08)|all_epithelial(64;2.55e-09)|Lung NSC(181;0.0053)|all_lung(186;0.00895)|Esophageal squamous(72;0.0166)					CTGTTCTCCAAGTTCCTTCCC	0.527000												
SERPINE1	5054	broad.mit.edu	37	7	100773794	100773794	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr7:100773794G>A	uc003uxt.2	+	3	512	c.364G>A	c.(364-366)GTC>ATC	p.V122I	SERPINE1_uc011kkj.1_Missense_Mutation_p.V107I|SERPINE1_uc003uxu.1_5'Flank	NM_000602	NP_000593	P05121	PAI1_HUMAN	plasminogen activator inhibitor-1 isoform 1	122					angiogenesis|cellular response to chemical stimulus|cellular response to lipopolysaccharide|chronological cell aging|defense response to Gram-negative bacterium|fibrinolysis|negative regulation of apoptosis|negative regulation of cell adhesion mediated by integrin|negative regulation of fibrinolysis|negative regulation of plasminogen activation|negative regulation of smooth muscle cell migration|negative regulation of smooth muscle cell-matrix adhesion|negative regulation of vascular wound healing|platelet activation|platelet degranulation|positive regulation of angiogenesis|positive regulation of interleukin-8 production|positive regulation of leukotriene production involved in inflammatory response|positive regulation of monocyte chemotaxis|positive regulation of receptor-mediated endocytosis|regulation of receptor activity	extracellular matrix|extracellular space|plasma membrane|platelet alpha granule lumen	protease binding|serine-type endopeptidase inhibitor activity			ovary(1)|lung(1)|central_nervous_system(1)	3	Lung NSC(181;0.136)|all_lung(186;0.182)				Atorvastatin(DB01076)|Dimethyl sulfoxide(DB01093)|Drotrecogin alfa(DB00055)|Simvastatin(DB00641)|Tenecteplase(DB00031)|Troglitazone(DB00197)|Urokinase(DB00013)	CGCGATCTTCGTCCAGCGGGA	0.597000												
MTSS1	9788	broad.mit.edu	37	8	125603445	125603445	+	Silent	SNP	G	G	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr8:125603445G>A	uc003yrk.2	-	4	774	c.240C>T	c.(238-240)ACC>ACT	p.T80T	MTSS1_uc003yrj.2_Silent_p.T80T|MTSS1_uc003yrl.2_Silent_p.T80T	NM_014751	NP_055566	O43312	MTSS1_HUMAN	metastasis suppressor 1	80	IMD.				actin cytoskeleton organization|cell adhesion|cellular component movement|filopodium assembly|transmembrane receptor protein tyrosine kinase signaling pathway	actin cytoskeleton|endocytic vesicle|ruffle	actin monomer binding|cytoskeletal adaptor activity|receptor binding|SH3 domain binding			ovary(1)	1	Ovarian(258;0.00438)|all_neural(195;0.00459)|Hepatocellular(40;0.108)		STAD - Stomach adenocarcinoma(47;0.00288)			TGCACATCCTGGTGAGAGCAG	0.517000												
C9orf79	286234	broad.mit.edu	37	9	90500005	90500005	+	Silent	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr9:90500005C>T	uc004app.3	+	4	638	c.603C>T	c.(601-603)ACC>ACT	p.T201T	C9orf79_uc004apo.1_Intron	NM_178828	NP_849150	Q6ZUB1	CI079_HUMAN	chromosome 9 open reading frame 79	201	Pro-rich.					integral to membrane				ovary(3)	3						TGGCCTCCACCCTGTCACCAG	0.622000												
SOHLH1	402381	broad.mit.edu	37	9	138588519	138588519	+	Silent	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr9:138588519C>T	uc004cgl.2	-	5	661	c.600G>A	c.(598-600)ACG>ACA	p.T200T	SOHLH1_uc010nbe.2_Silent_p.T200T	NM_001012415	NP_001012415	Q5JUK2	SOLH1_HUMAN	spermatogenesis and oogenesis specific basic	200					cell differentiation|multicellular organismal development|oogenesis|regulation of transcription, DNA-dependent|spermatogenesis|transcription, DNA-dependent	cytoplasm|nucleus	DNA binding			breast(1)|central_nervous_system(1)	2		Myeloproliferative disorder(178;0.0511)		OV - Ovarian serous cystadenocarcinoma(145;1.66e-07)|Epithelial(140;1.11e-06)|all cancers(34;6.45e-05)		CACACTTGTCCGTGCCCAGGG	0.682000												
BCOR	54880	broad.mit.edu	37	X	39932669	39932669	+	Nonsense_Mutation	SNP	C	C	A			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chrX:39932669C>A	uc004den.3	-	4	2222	c.1930G>T	c.(1930-1932)GAG>TAG	p.E644*	BCOR_uc004dep.3_Nonsense_Mutation_p.E644*|BCOR_uc004deo.3_Nonsense_Mutation_p.E644*|BCOR_uc004dem.3_Nonsense_Mutation_p.E644*|BCOR_uc004deq.3_Nonsense_Mutation_p.E644*	NM_001123385	NP_001116857	Q6W2J9	BCOR_HUMAN	BCL-6 interacting corepressor isoform c	644	Pro-rich.				heart development|histone H2A monoubiquitination|negative regulation of bone mineralization|negative regulation of histone H3-K36 methylation|negative regulation of histone H3-K4 methylation|negative regulation of tooth mineralization|negative regulation of transcription from RNA polymerase II promoter|odontogenesis|palate development|specification of axis polarity|transcription, DNA-dependent	nucleus	heat shock protein binding|histone deacetylase binding|transcription corepressor activity|transcription factor binding|transcription regulatory region DNA binding			ovary(2)|kidney(1)|central_nervous_system(1)	4						CTGAATGCCTCATTTGGAGAC	0.547000												
PAK3	5063	broad.mit.edu	37	X	110391110	110391110	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chrX:110391110C>T	uc004epa.2	+	4	494	c.467C>T	c.(466-468)ACA>ATA	p.T156I	PAK3_uc010npt.1_Missense_Mutation_p.T141I|PAK3_uc010npu.1_Missense_Mutation_p.T141I|PAK3_uc004eoy.1_5'UTR|PAK3_uc004eoz.2_Missense_Mutation_p.T141I|PAK3_uc011mst.1_RNA|PAK3_uc010npv.1_Missense_Mutation_p.T177I|PAK3_uc010npw.1_Missense_Mutation_p.T162I	NM_001128173	NP_001121645	O75914	PAK3_HUMAN	p21-activated kinase 3 isoform d	156	Linker.				multicellular organismal development		ATP binding|metal ion binding|protein serine/threonine kinase activity|SH3 domain binding			lung(6)|ovary(3)|large_intestine(1)	10						ATGAGCTTTACATCAGGAGGT	0.358000										TSP Lung(19;0.15)		
GPR112	139378	broad.mit.edu	37	X	135496392	135496392	+	Silent	SNP	G	G	T	rs150960878	byFrequency	TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chrX:135496392G>T	uc004ezu.1	+	25	9402	c.9111G>T	c.(9109-9111)CTG>CTT	p.L3037L	GPR112_uc010nsb.1_Silent_p.L2832L	NM_153834	NP_722576	Q8IZF6	GP112_HUMAN	G-protein coupled receptor 112	3037	Cytoplasmic (Potential).				neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			ovary(5)|large_intestine(2)|skin(2)|lung(1)|breast(1)|pancreas(1)	12	Acute lymphoblastic leukemia(192;0.000127)					AGCACAAACTGTTGACGCCAT	0.408000												
GLYATL2	219970	broad.mit.edu	37	11	58605807	58605807	+	Frame_Shift_Del	DEL	T	T	-			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr11:58605806_58605806GT>G	uc001nnd.4	-	2	245	c.114_114AC>C	c.(112-114)aacfs	p.N38fs	GLYATL2_uc009ymq.3_Frame_Shift_Del_p.N38fs	NM_145016	NP_659453	Q8WU03	GLYL2_HUMAN	Homo sapiens glycine-N-acyltransferase-like 2 (GLYATL2), mRNA.	38						mitochondrion	glycine N-acyltransferase activity			breast(1)|kidney(1)|large_intestine(3)|lung(12)|ovary(1)|skin(1)|stomach(2)|upper_aerodigestive_tract(2)	23		Breast(21;0.0044)|all_epithelial(135;0.0216)			Glycine(DB00145)	TGTTGAAAGGGTTTTTATCTT	0.428												
SERPINB7	8710	broad.mit.edu	37	18	61460423	61460424	+	Frame_Shift_Ins	INS	-	-	T			TCGA-CG-4455-01A-01D-1158-08	TCGA-CG-4455-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e2386c96-488e-4ddd-9d4c-fdea808aee19	9fc0cbc4-e8d8-4e74-ad52-327e4e1afe98	g.chr18:61460422_61460423G>GT	uc002ljl.3	+	3	343_344	c.247_248G>GT	c.(247-249)gttfs	p.V83fs	SERPINB7_uc002ljm.3_Frame_Shift_Ins_p.V83fs|SERPINB7_uc010xet.2_Frame_Shift_Ins_p.V66fs|SERPINB7_uc010dqg.3_Frame_Shift_Ins_p.V83fs	NM_001040147	NP_003775	O75635	SPB7_HUMAN	Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 7 (SERPINB7), transcript variant 2, mRNA.	83					regulation of proteolysis	cytoplasm	serine-type endopeptidase inhibitor activity			central_nervous_system(1)|endometrium(1)|kidney(4)|large_intestine(3)|lung(14)|prostate(1)|skin(3)	27		Esophageal squamous(42;0.129)				ACTGAAAAGAGTTTTTTCTGAT	0.327