Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values
PTCHD2	57540	broad.mit.edu	37	1	11579853	11579853	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:11579853C>T	uc001ash.3	+	9	2254	c.2116C>T	c.(2116-2118)CGC>TGC	p.R706C	PTCHD2_uc001asi.1_Missense_Mutation_p.R706C	NM_020780	NP_065831	Q9P2K9	PTHD2_HUMAN	patched domain containing 2	706	Cytoplasmic (Potential).				cholesterol homeostasis|regulation of lipid transport|smoothened signaling pathway	endoplasmic reticulum|integral to membrane|nuclear membrane	hedgehog receptor activity			skin(3)|ovary(2)|pancreas(1)|breast(1)	7	Ovarian(185;0.249)	Lung NSC(185;4.16e-05)|all_lung(284;4.76e-05)|Renal(390;0.000147)|Breast(348;0.00093)|Colorectal(325;0.00205)|Hepatocellular(190;0.00913)|Ovarian(437;0.00965)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;3.13e-07)|COAD - Colon adenocarcinoma(227;4.83e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000325)|Kidney(185;0.000877)|KIRC - Kidney renal clear cell carcinoma(229;0.00273)|STAD - Stomach adenocarcinoma(313;0.00766)|READ - Rectum adenocarcinoma(331;0.0549)		CACGGGCAGCCGCGGCCATCT	0.667000												
USP48	84196	broad.mit.edu	37	1	22079022	22079022	+	Silent	SNP	A	A	C			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:22079022A>C	uc001bfb.2	-	5	901	c.663T>G	c.(661-663)ACT>ACG	p.T221T	USP48_uc010odq.1_Silent_p.T221T|USP48_uc009vqc.2_Silent_p.T221T|USP48_uc001bfc.2_Silent_p.T221T|USP48_uc001bfe.1_Silent_p.T221T|USP48_uc001bff.2_Silent_p.T221T	NM_032236	NP_115612	Q86UV5	UBP48_HUMAN	ubiquitin specific protease 48 isoform a	221					ubiquitin-dependent protein catabolic process	mitochondrion|nucleus	cysteine-type peptidase activity|ubiquitin thiolesterase activity			ovary(1)|lung(1)	2		Colorectal(325;3.46e-05)|all_lung(284;4.29e-05)|Lung NSC(340;4.66e-05)|Renal(390;0.000219)|Breast(348;0.00222)|Ovarian(437;0.00308)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0182)|OV - Ovarian serous cystadenocarcinoma(117;4.74e-26)|COAD - Colon adenocarcinoma(152;1.3e-05)|GBM - Glioblastoma multiforme(114;1.86e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000614)|STAD - Stomach adenocarcinoma(196;0.00644)|KIRC - Kidney renal clear cell carcinoma(1967;0.00711)|Lung(427;0.0327)|READ - Rectum adenocarcinoma(331;0.0657)|LUSC - Lung squamous cell carcinoma(448;0.0753)		AGACTTACACAGTTACATAGG	0.348000												
ELTD1	64123	broad.mit.edu	37	1	79404873	79404873	+	Missense_Mutation	SNP	T	T	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:79404873T>A	uc001diq.3	-	4	552	c.396A>T	c.(394-396)AAA>AAT	p.K132N		NM_022159	NP_071442	Q9HBW9	ELTD1_HUMAN	EGF, latrophilin and seven transmembrane domain	132	Extracellular (Potential).				neuropeptide signaling pathway	integral to membrane|plasma membrane	calcium ion binding|G-protein coupled receptor activity			ovary(1)|skin(1)	2				COAD - Colon adenocarcinoma(225;0.0905)|Colorectal(170;0.103)|all cancers(265;0.105)|Epithelial(280;0.148)		TTCTACTTACTTTTGTTAAAG	0.254000												
COL24A1	255631	broad.mit.edu	37	1	86591429	86591429	+	Missense_Mutation	SNP	A	A	G			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:86591429A>G	uc001dlj.2	-	3	632	c.590T>C	c.(589-591)TTT>TCT	p.F197S	COL24A1_uc010osd.1_5'UTR|COL24A1_uc001dlk.2_RNA|COL24A1_uc010ose.1_RNA|COL24A1_uc010osf.1_RNA|COL24A1_uc009wcq.2_Missense_Mutation_p.F197S	NM_152890	NP_690850	Q17RW2	COOA1_HUMAN	collagen, type XXIV, alpha 1 precursor	197	TSP N-terminal.|Laminin G-like.				cell adhesion	collagen	extracellular matrix structural constituent			ovary(3)|central_nervous_system(1)|skin(1)	5				all cancers(265;0.0627)|Epithelial(280;0.0689)		ATTAGAATCAAAGGTCTGAAC	0.323000												
HIST2H2AB	317772	broad.mit.edu	37	1	149859408	149859408	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:149859408G>A	uc001ete.2	-	1	59	c.59C>T	c.(58-60)TCC>TTC	p.S20F	HIST2H2BE_uc001etc.2_5'Flank	NM_175065	NP_778235	Q8IUE6	H2A2B_HUMAN	histone cluster 2, H2ab	20					nucleosome assembly	nucleosome|nucleus	DNA binding			ovary(1)|breast(1)	2	Breast(34;0.0124)|all_hematologic(923;0.127)		STAD - Stomach adenocarcinoma(528;0.133)|LUSC - Lung squamous cell carcinoma(543;0.221)			ACCAGCGCGGGACGAGCGCGA	0.637000												
FCRL5	83416	broad.mit.edu	37	1	157508895	157508895	+	Silent	SNP	C	C	T	rs139032379	byFrequency	TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:157508895C>T	uc001fqu.2	-	7	1541	c.1383G>A	c.(1381-1383)GCG>GCA	p.A461A	FCRL5_uc009wsm.2_Silent_p.A461A|FCRL5_uc010phv.1_Silent_p.A461A|FCRL5_uc010phw.1_Silent_p.A376A|FCRL5_uc001fqv.1_Silent_p.A461A|FCRL5_uc010phx.1_Silent_p.A212A	NM_031281	NP_112571	Q96RD9	FCRL5_HUMAN	Fc receptor-like 5	461	Extracellular (Potential).|Ig-like C2-type 4.					integral to membrane|plasma membrane	receptor activity			ovary(3)|breast(2)|central_nervous_system(1)	6	all_hematologic(112;0.0378)|Hepatocellular(266;0.178)	Prostate(1639;0.231)				AGAGGCTCACCGCCTTACTGC	0.582000												
OR10J3	441911	broad.mit.edu	37	1	159284373	159284373	+	Missense_Mutation	SNP	A	A	C			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:159284373A>C	uc010piu.1	-	1	77	c.77T>G	c.(76-78)CTT>CGT	p.L26R		NM_001004467	NP_001004467	Q5JRS4	O10J3_HUMAN	olfactory receptor, family 10, subfamily J,	26	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(2)	2	all_hematologic(112;0.0429)					AAAGAAGACAAGTTTGTGCTG	0.448000												
ATP1A4	480	broad.mit.edu	37	1	160136448	160136448	+	Missense_Mutation	SNP	G	G	A	rs139315814		TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:160136448G>A	uc001fve.3	+	8	1657	c.1178G>A	c.(1177-1179)CGC>CAC	p.R393H	ATP1A4_uc001fvf.3_RNA|ATP1A4_uc001fvg.2_5'UTR	NM_144699	NP_653300	Q13733	AT1A4_HUMAN	Na+/K+ -ATPase alpha 4 subunit isoform 1	393	Cytoplasmic (Potential).				ATP biosynthetic process|ATP hydrolysis coupled proton transport|regulation of cellular pH|sperm motility	sodium:potassium-exchanging ATPase complex	ATP binding|metal ion binding|sodium:potassium-exchanging ATPase activity			ovary(2)|skin(2)	4	all_cancers(52;2.56e-18)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.111)			ACCCAGAACCGCATGACCGTC	0.577000												
TNN	63923	broad.mit.edu	37	1	175067562	175067562	+	Silent	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:175067562C>T	uc001gkl.1	+	9	2063	c.1950C>T	c.(1948-1950)TAC>TAT	p.Y650Y	TNN_uc010pmx.1_Silent_p.Y561Y	NM_022093	NP_071376	Q9UQP3	TENN_HUMAN	tenascin N precursor	650	Fibronectin type-III 5.				cell growth|cell migration|signal transduction	extracellular space|proteinaceous extracellular matrix				large_intestine(5)|ovary(3)|central_nervous_system(1)	9		Breast(1374;0.000962)		KIRC - Kidney renal clear cell carcinoma(1967;0.00198)		TTGACAAGTACGTGGTGCGCT	0.597000												
LAMC1	3915	broad.mit.edu	37	1	183087207	183087207	+	Missense_Mutation	SNP	T	T	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:183087207T>A	uc001gpy.3	+	11	2173	c.1916T>A	c.(1915-1917)CTT>CAT	p.L639H		NM_002293	NP_002284	P11047	LAMC1_HUMAN	laminin, gamma 1 precursor	639	Laminin IV type A.				axon guidance|cell migration|endoderm development|extracellular matrix disassembly|hemidesmosome assembly|positive regulation of epithelial cell proliferation|protein complex assembly|substrate adhesion-dependent cell spreading	extracellular space|laminin-1 complex|laminin-10 complex|laminin-11 complex	extracellular matrix structural constituent			ovary(3)|large_intestine(1)|kidney(1)	5					Alteplase(DB00009)|Anistreplase(DB00029)|Reteplase(DB00015)|Tenecteplase(DB00031)	AGGCCTGCTCTTACCCCTTTT	0.423000												
EPRS	2058	broad.mit.edu	37	1	220153467	220153467	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:220153467G>A	uc001hly.1	-	26	3941	c.3671C>T	c.(3670-3672)ACA>ATA	p.T1224I		NM_004446	NP_004437	P07814	SYEP_HUMAN	glutamyl-prolyl tRNA synthetase	1224	Prolyl-tRNA synthetase.				glutamyl-tRNA aminoacylation|prolyl-tRNA aminoacylation|protein complex assembly	cytosol|soluble fraction	ATP binding|glutamate-tRNA ligase activity|proline-tRNA ligase activity|protein binding|RNA binding			ovary(1)|skin(1)	2				GBM - Glioblastoma multiforme(131;0.0735)	L-Glutamic Acid(DB00142)|L-Proline(DB00172)	TGCTTCTATTGTAGTTGTATA	0.413000												
URB2	9816	broad.mit.edu	37	1	229772123	229772123	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:229772123C>T	uc001hts.1	+	4	1899	c.1763C>T	c.(1762-1764)CCG>CTG	p.P588L	URB2_uc009xfd.1_Missense_Mutation_p.P588L	NM_014777	NP_055592	Q14146	URB2_HUMAN	URB2 ribosome biogenesis 2 homolog	588						nucleolus				central_nervous_system(2)|ovary(1)	3						GCCCTTCTCCCGGACACCCCA	0.612000												
ALOX5	240	broad.mit.edu	37	10	45938960	45938960	+	Silent	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr10:45938960C>T	uc001jce.2	+	11	1647	c.1548C>T	c.(1546-1548)TAC>TAT	p.Y516Y	ALOX5_uc009xmt.2_Silent_p.Y484Y|ALOX5_uc010qfg.1_Silent_p.Y516Y	NM_000698	NP_000689	P09917	LOX5_HUMAN	arachidonate 5-lipoxygenase	516	Lipoxygenase.				hormone biosynthetic process|leukotriene biosynthetic process|prostanoid metabolic process	cytosol|nuclear envelope lumen|nuclear matrix|nuclear membrane	arachidonate 5-lipoxygenase activity|iron ion binding|lipoxygenase activity|protein binding			ovary(1)|pancreas(1)	2		Lung SC(717;0.0257)			Diethylcarbamazine(DB00711)|Hydrocortisone(DB00741)|Leflunomide(DB01097)|Masoprocol(DB00179)|Meclofenamic acid(DB00939)|Minocycline(DB01017)|Montelukast(DB00471)|Quinacrine(DB01103)|Vitamin E(DB00163)|Zileuton(DB00744)	TCTACGTGTACGGCATGCGGG	0.692000												
MYOF	26509	broad.mit.edu	37	10	95069867	95069867	+	Silent	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr10:95069867G>A	uc001kin.2	-	53	6180	c.6057C>T	c.(6055-6057)ATC>ATT	p.I2019I	MYOF_uc001kio.2_Silent_p.I2006I|MYOF_uc009xue.2_RNA	NM_013451	NP_038479	Q9NZM1	MYOF_HUMAN	myoferlin isoform a	2019	Cytoplasmic (Potential).				blood circulation|muscle contraction|plasma membrane repair	caveola|cytoplasmic vesicle membrane|integral to membrane|nuclear membrane	phospholipid binding|protein binding			ovary(3)|breast(1)	4						GGCGCCACACGATGAACTTCA	0.542000												
MRGPRX1	259249	broad.mit.edu	37	11	18956197	18956197	+	Silent	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr11:18956197G>A	uc001mpg.2	-	1	353	c.135C>T	c.(133-135)AAC>AAT	p.N45N		NM_147199	NP_671732	Q96LB2	MRGX1_HUMAN	MAS-related GPR, member X1	45	Helical; Name=1; (Potential).				acute-phase response	integral to membrane|plasma membrane	G-protein coupled receptor activity			pancreas(2)|central_nervous_system(1)	3						GCACAACTGCGTTTCCTGTCA	0.577000												
MUC15	143662	broad.mit.edu	37	11	26587340	26587340	+	Silent	SNP	A	A	G			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr11:26587340A>G	uc001mqx.2	-	2	332	c.66T>C	c.(64-66)CAT>CAC	p.H22H	ANO3_uc010rdr.1_Intron|ANO3_uc001mqt.3_Intron|ANO3_uc010rds.1_Intron|ANO3_uc010rdt.1_Intron|MUC15_uc001mqw.2_Silent_p.H49H|MUC15_uc001mqy.2_Silent_p.H49H	NM_145650	NP_663625	Q8N387	MUC15_HUMAN	mucin 15 isoform b	22						extracellular region|integral to membrane|plasma membrane				ovary(1)|central_nervous_system(1)|pancreas(1)	3						TTTCTTTTCCATGGCTCCCCG	0.328000												
ZBTB44	29068	broad.mit.edu	37	11	130109742	130109742	+	Silent	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr11:130109742C>T	uc001qga.2	-	3	1462	c.1068G>A	c.(1066-1068)ACG>ACA	p.T356T	ZBTB44_uc001qgb.3_Silent_p.T356T|ZBTB44_uc001qfx.2_RNA|ZBTB44_uc001qgc.1_Silent_p.T356T|ZBTB44_uc001qfz.2_Silent_p.T356T	NM_014155	NP_054874	Q8NCP5	ZBT44_HUMAN	zinc finger and BTB domain containing 44	356					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(1)	1	all_hematologic(175;0.0429)	Lung NSC(97;0.000601)|Breast(109;0.000962)|all_lung(97;0.00125)|Medulloblastoma(222;0.0425)|all_neural(223;0.0837)		OV - Ovarian serous cystadenocarcinoma(99;0.0192)|Lung(977;0.235)		TAGTGCTAGACGTGCTTTGAA	0.438000												
SRGAP1	57522	broad.mit.edu	37	12	64488927	64488929	+	Missense_Mutation	TNP	TTC	TTC	AAA			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr12:64488927_64488929TTC>AAA	uc010ssp.1	+	14	1677_1679	c.1621_1623TTC>AAA	c.(1621-1623)TTC>AAA	p.F541K	SRGAP1_uc001srv.2_Missense_Mutation_p.F478K	NM_020762	NP_065813	Q7Z6B7	SRGP1_HUMAN	SLIT-ROBO Rho GTPase activating protein 1	541	Rho-GAP.				axon guidance	cytosol				ovary(2)|central_nervous_system(2)	4			GBM - Glioblastoma multiforme(3;0.000139)|BRCA - Breast invasive adenocarcinoma(9;0.225)	GBM - Glioblastoma multiforme(28;0.0608)		TCAGGGGATTTTCAGAGTGTCTG	0.404000												
RSRC2	65117	broad.mit.edu	37	12	122995657	122995657	+	Silent	SNP	T	T	C			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr12:122995657T>C	uc001ucr.2	-	7	950	c.804A>G	c.(802-804)GCA>GCG	p.A268A	RSRC2_uc001uco.2_Silent_p.A36A|RSRC2_uc001ucp.2_Silent_p.A209A|RSRC2_uc001ucq.2_Silent_p.A36A|RSRC2_uc001ucs.2_Silent_p.A36A|RSRC2_uc001uct.2_Silent_p.A220A|RSRC2_uc001ucu.2_Silent_p.A268A	NM_023012	NP_075388	Q7L4I2	RSRC2_HUMAN	arginine/serine-rich coiled-coil 2 isoform a	268	Potential.									ovary(1)	1	all_neural(191;0.0837)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;5.14e-05)|Epithelial(86;0.000183)|BRCA - Breast invasive adenocarcinoma(302;0.201)		AAAAATTACCTGCAGCTATTT	0.244000												
NUPL1	9818	broad.mit.edu	37	13	25882042	25882042	+	Missense_Mutation	SNP	G	G	C			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr13:25882042G>C	uc001uqi.2	+	2	452	c.206G>C	c.(205-207)GGA>GCA	p.G69A	NUPL1_uc001uqg.1_Missense_Mutation_p.G69A|NUPL1_uc001uqj.2_Missense_Mutation_p.G69A	NM_014089	NP_054808	Q9BVL2	NUPL1_HUMAN	nucleoporin like 1 isoform a	69	14 X 2 AA repeats of F-G.|5.				carbohydrate metabolic process|glucose transport|mRNA transport|protein transport|regulation of glucose transport|transmembrane transport|viral reproduction	nuclear membrane|nuclear pore					0		Lung SC(185;0.0225)|Breast(139;0.0351)		all cancers(112;0.0092)|Epithelial(112;0.0477)|OV - Ovarian serous cystadenocarcinoma(117;0.165)|GBM - Glioblastoma multiforme(144;0.244)		GGGCTCTTTGGATCTAAACCT	0.458000												
DCLK1	9201	broad.mit.edu	37	13	36686282	36686282	+	Missense_Mutation	SNP	G	G	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr13:36686282G>T	uc001uvf.2	-	3	680	c.447C>A	c.(445-447)AAC>AAA	p.N149K		NM_004734	NP_004725	O15075	DCLK1_HUMAN	doublecortin-like kinase 1	149					cell differentiation|central nervous system development|endosome transport|intracellular signal transduction|response to virus	integral to plasma membrane	ATP binding|protein serine/threonine kinase activity|receptor signaling protein activity			stomach(6)|ovary(2)|skin(1)	9		Breast(139;0.0147)|Lung SC(185;0.0685)|Prostate(109;0.122)	KIRC - Kidney renal clear cell carcinoma(5;0.119)|Kidney(79;0.169)	all cancers(112;1.72e-06)|Epithelial(112;4.24e-05)|BRCA - Breast invasive adenocarcinoma(63;0.00159)|OV - Ovarian serous cystadenocarcinoma(117;0.0158)|GBM - Glioblastoma multiforme(144;0.0638)		TCACCGACCAGTTGGGGTTCA	0.468000												
GPC5	2262	broad.mit.edu	37	13	92345708	92345708	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr13:92345708G>A	uc010tif.1	+	3	959	c.593G>A	c.(592-594)CGC>CAC	p.R198H		NM_004466	NP_004457	P78333	GPC5_HUMAN	glypican 5 precursor	198						anchored to membrane|extracellular space|integral to plasma membrane|proteinaceous extracellular matrix	heparan sulfate proteoglycan binding			ovary(2)|skin(2)|upper_aerodigestive_tract(1)	5	all_cancers(3;1.43e-07)|all_neural(89;0.0804)|Medulloblastoma(90;0.163)	Lung NSC(4;0.00454)				CGGATGGCTCGCCGGGATGTG	0.502000												
ZNF219	51222	broad.mit.edu	37	14	21561022	21561022	+	Missense_Mutation	SNP	G	G	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr14:21561022G>T	uc001vzr.2	-	3	855	c.434C>A	c.(433-435)GCC>GAC	p.A145D	ZNF219_uc001vzs.2_Missense_Mutation_p.A145D|ZNF219_uc010aik.1_Missense_Mutation_p.A145D	NM_016423	NP_057507	Q9P2Y4	ZN219_HUMAN	zinc finger protein 219	145					negative regulation of transcription, DNA-dependent	integral to membrane|nucleus	DNA binding|histamine receptor activity|protein binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			central_nervous_system(1)	1	all_cancers(95;0.00185)		OV - Ovarian serous cystadenocarcinoma(11;9.86e-11)|Epithelial(56;1.27e-08)|all cancers(55;6.06e-08)	GBM - Glioblastoma multiforme(265;0.0191)		GGCAGGGGTGGCCTGCATGCC	0.677000											OREG0022565	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)
SSTR1	6751	broad.mit.edu	37	14	38678850	38678850	+	Missense_Mutation	SNP	T	T	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr14:38678850T>A	uc001wul.1	+	3	873	c.256T>A	c.(256-258)TAT>AAT	p.Y86N	SSTR1_uc010amu.1_Intron	NM_001049	NP_001040	P30872	SSR1_HUMAN	somatostatin receptor 1	86	Cytoplasmic (Potential).				digestion|G-protein signaling, coupled to cyclic nucleotide second messenger|negative regulation of cell proliferation|response to nutrient	integral to plasma membrane	somatostatin receptor activity			central_nervous_system(3)|ovary(1)|lung(1)	5	Hepatocellular(127;0.213)|Esophageal squamous(585;0.22)		Lung(238;3.93e-06)|LUAD - Lung adenocarcinoma(48;2.62e-05)|Epithelial(34;0.187)	GBM - Glioblastoma multiforme(112;0.00444)	Octreotide(DB00104)	GATCCTGCGCTATGCCAAGAT	0.557000												
C14orf182	283551	broad.mit.edu	37	14	50472506	50472506	+	Silent	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr14:50472506C>T	uc001wxi.1	-	1	1733	c.12G>A	c.(10-12)CGG>CGA	p.R4R		NM_001012706	NP_001012724	A1A4T8	CN182_HUMAN	hypothetical protein LOC283551	4											0						GGGTTGCCATCCGACCTGTCA	0.512000												
KIAA0586	9786	broad.mit.edu	37	14	58934502	58934502	+	Silent	SNP	C	C	G			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr14:58934502C>G	uc001xdv.3	+	15	2349	c.2076C>G	c.(2074-2076)GTC>GTG	p.V692V	KIAA0586_uc010trr.1_Silent_p.V809V|KIAA0586_uc001xdt.3_Silent_p.V724V|KIAA0586_uc001xdu.3_Silent_p.V753V|KIAA0586_uc010trs.1_Silent_p.V683V|KIAA0586_uc010trt.1_Silent_p.V628V|KIAA0586_uc010tru.1_Silent_p.V628V	NM_014749	NP_055564	E9PGW8	E9PGW8_HUMAN	talpid3 protein	692										ovary(1)	1						GAGTGATTGTCAGCAAGCCAC	0.388000												
AP4E1	23431	broad.mit.edu	37	15	51250862	51250862	+	Missense_Mutation	SNP	A	A	C			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr15:51250862A>C	uc001zyx.1	+	14	1752	c.1722A>C	c.(1720-1722)TTA>TTC	p.L574F		NM_007347	NP_031373	Q9UPM8	AP4E1_HUMAN	adaptor-related protein complex 4, epsilon 1	574					intracellular protein transport|vesicle-mediated transport	COPI vesicle coat	binding|structural molecule activity				0				all cancers(107;0.000893)|GBM - Glioblastoma multiforme(94;0.00364)		TTGAGAGATTAATCCATGAAT	0.363000												
IGDCC4	57722	broad.mit.edu	37	15	65678955	65678955	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr15:65678955C>T	uc002aou.1	-	17	3095	c.2885G>A	c.(2884-2886)GGT>GAT	p.G962D	IGDCC4_uc002aot.1_Missense_Mutation_p.G550D	NM_020962	NP_066013	Q8TDY8	IGDC4_HUMAN	immunoglobulin superfamily, DCC subclass, member	962	Helical; (Potential).					integral to membrane|plasma membrane				ovary(1)|pancreas(1)|skin(1)	3						CAGGCAGACACCCACGATGAT	0.642000											OREG0023195	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)
IQGAP1	8826	broad.mit.edu	37	15	90984881	90984881	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr15:90984881G>A	uc002bpl.1	+	8	894	c.793G>A	c.(793-795)GCT>ACT	p.A265T		NM_003870	NP_003861	P46940	IQGA1_HUMAN	IQ motif containing GTPase activating protein 1	265					energy reserve metabolic process|regulation of insulin secretion|small GTPase mediated signal transduction	actin filament|cytoplasm|midbody|nucleus|plasma membrane	calmodulin binding|GTPase inhibitor activity|protein phosphatase binding|Ras GTPase activator activity			ovary(2)|lung(2)|central_nervous_system(2)|pancreas(1)|skin(1)	8	Melanoma(11;0.00551)|Lung NSC(78;0.0237)|all_lung(78;0.0488)		BRCA - Breast invasive adenocarcinoma(143;0.0745)|KIRC - Kidney renal clear cell carcinoma(17;0.138)|Kidney(142;0.194)			ACTTTACCAGGCTAAGCAGGA	0.373000												
CHD2	1106	broad.mit.edu	37	15	93567880	93567880	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr15:93567880G>A	uc002bsp.2	+	39	6007	c.5432G>A	c.(5431-5433)AGA>AAA	p.R1811K		NM_001271	NP_001262	O14647	CHD2_HUMAN	chromodomain helicase DNA binding protein 2	1811					regulation of transcription from RNA polymerase II promoter	nucleus	ATP binding|ATP-dependent DNA helicase activity|DNA binding			ovary(1)|skin(1)	2	Lung NSC(78;0.00976)|all_lung(78;0.016)		BRCA - Breast invasive adenocarcinoma(143;0.0282)|OV - Ovarian serous cystadenocarcinoma(32;0.0814)			CCTTTGGAGAGATCACTAGAA	0.478000												
DNAH3	55567	broad.mit.edu	37	16	21031006	21031006	+	Missense_Mutation	SNP	C	C	G			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr16:21031006C>G	uc010vbe.1	-	41	5962	c.5962G>C	c.(5962-5964)GAT>CAT	p.D1988H		NM_017539	NP_060009	Q8TD57	DYH3_HUMAN	dynein, axonemal, heavy chain 3	1988					ciliary or flagellar motility|microtubule-based movement	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|microtubule motor activity			ovary(10)|skin(3)|large_intestine(2)|central_nervous_system(2)|upper_aerodigestive_tract(1)	18				GBM - Glioblastoma multiforme(48;0.207)		GGGTGGTTATCATCCATGCCC	0.423000												
SRCAP	10847	broad.mit.edu	37	16	30715408	30715408	+	Silent	SNP	C	C	G			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr16:30715408C>G	uc002dze.1	+	4	463	c.78C>G	c.(76-78)GGC>GGG	p.G26G	SRCAP_uc002dzf.2_RNA	NM_006662	NP_006653	Q6ZRS2	SRCAP_HUMAN	Snf2-related CBP activator protein	26					interspecies interaction between organisms|regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	Golgi apparatus|nucleus|protein complex	ATP binding|DNA binding|helicase activity|histone acetyltransferase activity|transcription coactivator activity			ovary(3)|skin(1)	4			Colorectal(24;0.198)			GCATGACAGGCAGCAATCCTG	0.418000												
CNTNAP4	85445	broad.mit.edu	37	16	76572099	76572099	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr16:76572099G>A	uc002feu.1	+	21	3467	c.3082G>A	c.(3082-3084)GCT>ACT	p.A1028T	CNTNAP4_uc002fev.1_Missense_Mutation_p.A892T|CNTNAP4_uc010chb.1_Missense_Mutation_p.A955T|CNTNAP4_uc002fex.1_Missense_Mutation_p.A1031T	NM_033401	NP_207837	Q9C0A0	CNTP4_HUMAN	cell recognition protein CASPR4 isoform 1	1028	Extracellular (Potential).				cell adhesion|signal transduction	integral to membrane	receptor binding			ovary(1)|pancreas(1)	2						CAGCTCCCACGCTGCTTCATT	0.363000												
SPATA22	84690	broad.mit.edu	37	17	3349846	3349846	+	Missense_Mutation	SNP	C	C	G			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr17:3349846C>G	uc002fvm.2	-	7	959	c.722G>C	c.(721-723)AGA>ACA	p.R241T	SPATA22_uc010vrg.1_Missense_Mutation_p.R225T|SPATA22_uc010vrf.1_Missense_Mutation_p.R241T|SPATA22_uc002fvn.2_Missense_Mutation_p.R241T|SPATA22_uc002fvo.2_Missense_Mutation_p.R241T|SPATA22_uc002fvp.2_Missense_Mutation_p.R241T|SPATA22_uc010ckf.2_Missense_Mutation_p.R198T	NM_032598	NP_115987	Q8NHS9	SPT22_HUMAN	spermatogenesis associated 22	241											0						AGAAATAATTCTTAAAGAACT	0.269000												
PCGF2	7703	broad.mit.edu	37	17	36895901	36895901	+	Silent	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr17:36895901G>A	uc002hqp.1	-	4	390	c.147C>T	c.(145-147)ACC>ACT	p.T49T	PCGF2_uc002hqn.1_Silent_p.T49T|PCGF2_uc002hqo.1_Silent_p.T49T|PCGF2_uc010cvo.1_5'UTR|PCGF2_uc002hqq.1_Silent_p.T49T	NM_007144	NP_009075	P35227	PCGF2_HUMAN	ring finger protein 110	49	RING-type.				negative regulation of transcription from RNA polymerase II promoter	PcG protein complex	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			central_nervous_system(1)|skin(1)	2	Breast(7;9.07e-22)					AGTATTTGTTGGTCTCCAGGT	0.607000												
CDK12	51755	broad.mit.edu	37	17	37649112	37649112	+	Silent	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr17:37649112C>T	uc010cvv.2	+	4	2803	c.2217C>T	c.(2215-2217)GGC>GGT	p.G739G	CDK12_uc010wef.1_Silent_p.G738G|CDK12_uc002hrw.3_Silent_p.G739G	NM_016507	NP_057591	Q9NYV4	CDK12_HUMAN	Cdc2-related kinase, arginine/serine-rich	739	ATP (By similarity).|Protein kinase.				mRNA processing|phosphorylation of RNA polymerase II C-terminal domain|protein autophosphorylation|regulation of MAP kinase activity|RNA splicing	nuclear cyclin-dependent protein kinase holoenzyme complex|nuclear speck|nucleolus	ATP binding|cyclin-dependent protein kinase activity|protein binding|RNA polymerase II carboxy-terminal domain kinase activity			ovary(10)|lung(4)|breast(2)|skin(2)|large_intestine(1)	19						GAACCTATGGCCAAGTATATA	0.378000										TCGA Ovarian(9;0.13)		
TRIM37	4591	broad.mit.edu	37	17	57109276	57109276	+	Silent	SNP	A	A	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr17:57109276A>T	uc002iwy.3	-	18	2373	c.1929T>A	c.(1927-1929)GCT>GCA	p.A643A	TRIM37_uc002iwz.3_Silent_p.A643A|TRIM37_uc002ixa.3_Silent_p.A521A|TRIM37_uc010woc.1_Silent_p.A609A	NM_001005207	NP_001005207	O94972	TRI37_HUMAN	tripartite motif-containing 37 protein	643						perinuclear region of cytoplasm|peroxisome	ligase activity|protein binding|zinc ion binding			lung(2)|pancreas(2)|ovary(1)|skin(1)|breast(1)	7	Medulloblastoma(34;0.0922)|all_neural(34;0.101)					GCAGAAGTGAAGCAGGTGGGC	0.368000									Mulibrey_Nanism			
EVI5L	115704	broad.mit.edu	37	19	7914143	7914143	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr19:7914143C>T	uc002min.2	+	5	708	c.554C>T	c.(553-555)GCA>GTA	p.A185V	EVI5L_uc010xjz.1_Missense_Mutation_p.A185V|EVI5L_uc002mio.1_5'Flank	NM_145245	NP_660288	Q96CN4	EVI5L_HUMAN	ecotropic viral integration site 5-like isoform	185	Rab-GAP TBC.					intracellular	protein binding|Rab GTPase activator activity			ovary(1)	1						CCCTTCTAGGCATACTCGCTG	0.652000												
LDLR	3949	broad.mit.edu	37	19	11218184	11218184	+	Nonsense_Mutation	SNP	G	G	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr19:11218184G>T	uc002mqk.3	+	6	1102	c.934G>T	c.(934-936)GAG>TAG	p.E312*	LDLR_uc010xlk.1_Nonsense_Mutation_p.E312*|LDLR_uc010xll.1_Nonsense_Mutation_p.E271*|LDLR_uc010xlm.1_Nonsense_Mutation_p.E165*|LDLR_uc010xln.1_Nonsense_Mutation_p.E185*|LDLR_uc010xlo.1_Nonsense_Mutation_p.E144*	NM_000527	NP_000518	P01130	LDLR_HUMAN	low density lipoprotein receptor precursor	312	Extracellular (Potential).|LDL-receptor class A 7.				cholesterol homeostasis|cholesterol metabolic process|interspecies interaction between organisms|intestinal cholesterol absorption|low-density lipoprotein particle clearance|receptor-mediated endocytosis	clathrin-coated endocytic vesicle membrane|coated pit|early endosome|endosome membrane|external side of plasma membrane|integral to plasma membrane|low-density lipoprotein particle|lysosome	calcium ion binding|low-density lipoprotein receptor activity|protein binding|very-low-density lipoprotein particle receptor activity			ovary(2)|skin(2)	4		Lung NSC(9;0.000245)|Renal(1328;0.0007)|Hepatocellular(1079;0.0524)		GBM - Glioblastoma multiforme(1328;1.36e-05)|STAD - Stomach adenocarcinoma(1328;0.000766)|Lung(535;0.197)	Methyl aminolevulinate(DB00992)|Porfimer(DB00707)	ACCCATCAAAGAGTGCGGTGA	0.552000												
PSG1	5669	broad.mit.edu	37	19	43372329	43372329	+	Silent	SNP	G	G	A	rs142917150		TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr19:43372329G>A	uc002ovb.2	-	5	1305	c.1167C>T	c.(1165-1167)AGC>AGT	p.S389S	PSG3_uc002ouf.2_Intron|PSG1_uc002oug.1_Intron|PSG11_uc002ouw.2_Intron|PSG7_uc002ous.1_Intron|PSG7_uc002out.1_Intron|PSG10_uc002ouv.1_Intron|PSG1_uc002oun.2_Intron|PSG1_uc002our.1_Silent_p.S389S|PSG1_uc010eio.1_Silent_p.S389S|PSG1_uc002oux.1_Silent_p.S318S|PSG1_uc002ouy.1_Silent_p.S296S|PSG1_uc002ouz.1_Silent_p.S389S|PSG1_uc002ova.1_Silent_p.S296S|PSG1_uc002ovc.2_Silent_p.S296S|PSG1_uc002ovd.1_Silent_p.S389S	NM_006905	NP_008836	P11464	PSG1_HUMAN	pregnancy specific beta-1-glycoprotein 1	389	Ig-like C2-type 3.				female pregnancy	extracellular region				ovary(2)	2		Prostate(69;0.00682)				CATAGAGCCCGCTATGCTTTG	0.468000												
LRRC4B	94030	broad.mit.edu	37	19	51021716	51021716	+	Silent	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr19:51021716G>A	uc002pss.2	-	3	1391	c.1254C>T	c.(1252-1254)GAC>GAT	p.D418D		NM_001080457	NP_001073926	Q9NT99	LRC4B_HUMAN	leucine rich repeat containing 4B precursor	418	Extracellular (Potential).|Ig-like C2-type.					cell junction|integral to membrane|presynaptic membrane				central_nervous_system(1)|skin(1)	2		all_neural(266;0.131)		OV - Ovarian serous cystadenocarcinoma(262;0.00284)|GBM - Glioblastoma multiforme(134;0.0188)		TAAGCGTGCCGTCATGCAGGA	0.652000												
SIGLEC14	100049587	broad.mit.edu	37	19	52148732	52148732	+	Missense_Mutation	SNP	G	G	C			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr19:52148732G>C	uc002pxf.3	-	4	872	c.752C>G	c.(751-753)ACA>AGA	p.T251R		NM_001098612	NP_001092082	Q08ET2	SIG14_HUMAN	sialic acid binding Ig-like lectin 14 precursor	251	Extracellular (Potential).|Ig-like C2-type 2.				cell adhesion	integral to membrane|plasma membrane	protein binding|sugar binding			ovary(1)	1		all_neural(266;0.0299)		GBM - Glioblastoma multiforme(134;0.000965)|OV - Ovarian serous cystadenocarcinoma(262;0.0195)		TTTCCTACCTGTGCCTGTGCC	0.552000												
HAS1	3036	broad.mit.edu	37	19	52220238	52220238	+	Missense_Mutation	SNP	C	C	G			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr19:52220238C>G	uc002pxo.1	-	3	946	c.911G>C	c.(910-912)TGC>TCC	p.C304S	HAS1_uc010epc.1_5'UTR|HAS1_uc010epd.1_Missense_Mutation_p.C269S|HAS1_uc002pxn.1_Missense_Mutation_p.C311S|HAS1_uc002pxp.1_Missense_Mutation_p.C303S	NM_001523	NP_001514	Q92839	HAS1_HUMAN	hyaluronan synthase 1	304	Cytoplasmic (Potential).				cell adhesion	integral to plasma membrane	hyaluronan synthase activity|protein binding			ovary(1)|pancreas(1)	2		all_neural(266;0.0189)|Medulloblastoma(540;0.146)		GBM - Glioblastoma multiforme(134;0.00102)|OV - Ovarian serous cystadenocarcinoma(262;0.0177)		ACCGCTGATGCAGGATACACA	0.507000												
NRXN1	9378	broad.mit.edu	37	2	51255085	51255085	+	Silent	SNP	A	A	C			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr2:51255085A>C	uc010fbq.2	-	2	1804	c.327T>G	c.(325-327)GTT>GTG	p.V109V	NRXN1_uc002rxe.3_Silent_p.V109V|NRXN1_uc002rxd.1_Silent_p.V109V	NM_001135659	NP_001129131	P58400	NRX1B_HUMAN	neurexin 1 isoform alpha2 precursor	Error:AA_residue_mismatch_between_GAF_and_UniProt_prot_seqs_after_alignment					angiogenesis|neuron cell-cell adhesion|neuronal signal transduction	cell surface|endocytic vesicle|integral to membrane|presynaptic membrane	cell adhesion molecule binding|receptor binding			ovary(2)	2		all_hematologic(82;0.152)|Acute lymphoblastic leukemia(82;0.192)	Lung(47;0.0813)|LUSC - Lung squamous cell carcinoma(58;0.116)			CGCCGTCGTTAACCGGCGTGT	0.662000												
ANKRD53	79998	broad.mit.edu	37	2	71211788	71211788	+	Silent	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr2:71211788C>T	uc002shl.3	+	6	1152	c.951C>T	c.(949-951)CAC>CAT	p.H317H	ANKRD53_uc002shk.3_3'UTR|ANKRD53_uc002shm.3_3'UTR	NM_001115116	NP_001108588	Q8N9V6	ANR53_HUMAN	ankyrin repeat domain 53 isoform a	317											0						AGTGGCTCCACGGCAAGCTGC	0.572000											OREG0014687	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)
ST6GAL2	84620	broad.mit.edu	37	2	107459775	107459775	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr2:107459775C>T	uc002tdq.2	-	2	778	c.659G>A	c.(658-660)CGC>CAC	p.R220H	ST6GAL2_uc002tdr.2_Missense_Mutation_p.R220H|ST6GAL2_uc002tds.3_Missense_Mutation_p.R220H	NM_001142351	NP_001135823	Q96JF0	SIAT2_HUMAN	ST6 beta-galactosamide	220	Lumenal (Potential).				growth|multicellular organismal development|oligosaccharide metabolic process|protein glycosylation	Golgi cisterna membrane|integral to Golgi membrane	beta-galactoside alpha-2,6-sialyltransferase activity			pancreas(6)|ovary(4)|skin(1)	11						CTTCTGCAGGCGCGGGTTCAG	0.647000												
ZNF385B	151126	broad.mit.edu	37	2	180309654	180309654	+	Silent	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr2:180309654C>T	uc002unn.3	-	9	1750	c.1146G>A	c.(1144-1146)AAG>AAA	p.K382K	ZNF385B_uc002unj.2_Silent_p.K280K|ZNF385B_uc002unk.2_RNA|ZNF385B_uc002unl.2_Silent_p.K279K|ZNF385B_uc002unm.2_Silent_p.K306K	NM_152520	NP_689733	Q569K4	Z385B_HUMAN	zinc finger protein 385B isoform 1	382						nucleus	nucleic acid binding|zinc ion binding			ovary(1)	1			Epithelial(96;0.174)|OV - Ovarian serous cystadenocarcinoma(117;0.201)			TGTATTTTGGCTTCAGTGGTT	0.468000												
DNAH7	56171	broad.mit.edu	37	2	196749409	196749409	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr2:196749409G>A	uc002utj.3	-	35	5764	c.5663C>T	c.(5662-5664)ACG>ATG	p.T1888M		NM_018897	NP_061720	Q8WXX0	DYH7_HUMAN	dynein, axonemal, heavy chain 7	1888					ciliary or flagellar motility|microtubule-based movement	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|microtubule motor activity			skin(10)|ovary(2)	12						TAATTTAAACGTATTTCGAGT	0.363000												
COL6A3	1293	broad.mit.edu	37	2	238249780	238249780	+	Missense_Mutation	SNP	G	G	C	rs144249704		TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr2:238249780G>C	uc002vwl.2	-	38	8064	c.7779C>G	c.(7777-7779)ATC>ATG	p.I2593M	COL6A3_uc002vwo.2_Missense_Mutation_p.I2387M|COL6A3_uc010znj.1_Missense_Mutation_p.I1986M|COL6A3_uc002vwj.2_Translation_Start_Site	NM_004369	NP_004360	P12111	CO6A3_HUMAN	alpha 3 type VI collagen isoform 1 precursor	2593	Nonhelical region.				axon guidance|cell adhesion|muscle organ development	collagen type VI|extracellular space	serine-type endopeptidase inhibitor activity			ovary(8)|central_nervous_system(6)|skin(2)|upper_aerodigestive_tract(1)|pancreas(1)	18		Breast(86;0.000301)|Renal(207;0.000966)|all_hematologic(139;0.067)|Ovarian(221;0.0694)|all_lung(227;0.0943)|Melanoma(123;0.203)		Epithelial(121;1.23e-21)|OV - Ovarian serous cystadenocarcinoma(60;1.34e-10)|Kidney(56;5.71e-09)|KIRC - Kidney renal clear cell carcinoma(57;1.51e-07)|BRCA - Breast invasive adenocarcinoma(100;0.00025)|Lung(119;0.0142)|LUSC - Lung squamous cell carcinoma(224;0.034)		AGGATGGGTCGATGTTGCAGA	0.527000												
OTOR	56914	broad.mit.edu	37	20	16730657	16730657	+	Splice_Site	SNP	T	T	C			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr20:16730657T>C	uc002wpj.2	+	3	407	c.363_splice	c.e3+2	p.T121_splice	OTOR_uc002wpk.2_Splice_Site	NM_020157	NP_064542	Q9NRC9	OTOR_HUMAN	otoraplin precursor						sensory perception of sound	extracellular region				ovary(1)|central_nervous_system(1)	2						CCCACCACGGTAAGCATCTCA	0.483000												
CST8	10047	broad.mit.edu	37	20	23472436	23472436	+	Silent	SNP	C	C	T	rs150145986		TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr20:23472436C>T	uc002wth.1	+	2	489	c.132C>T	c.(130-132)AAC>AAT	p.N44N		NM_005492	NP_005483	O60676	CST8_HUMAN	cystatin 8 precursor	44						extracellular region	cysteine-type endopeptidase inhibitor activity				0	Colorectal(13;0.0431)|Lung NSC(19;0.235)					CAAATGCCAACGTGAAGCAGT	0.507000												
PTGIS	5740	broad.mit.edu	37	20	48124559	48124559	+	Missense_Mutation	SNP	G	G	C			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr20:48124559G>C	uc002xut.2	-	10	1455	c.1401C>G	c.(1399-1401)ATC>ATG	p.I467M	PTGIS_uc010zyi.1_Missense_Mutation_p.I328M	NM_000961	NP_000952	Q16647	PTGIS_HUMAN	prostaglandin I2 synthase	467					hormone biosynthetic process|prostaglandin biosynthetic process|xenobiotic metabolic process	endoplasmic reticulum lumen|endoplasmic reticulum membrane|integral to membrane	electron carrier activity|heme binding|monooxygenase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|prostaglandin-I synthase activity			skin(2)|ovary(1)	3			BRCA - Breast invasive adenocarcinoma(12;2.37e-05)|COAD - Colon adenocarcinoma(4;0.14)|Colorectal(8;0.166)		Phenylbutazone(DB00812)	CATCTGCGTTGATCAGCTCCA	0.577000												
KCNJ6	3763	broad.mit.edu	37	21	39086934	39086934	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr21:39086934C>T	uc011aej.1	-	3	579	c.526G>A	c.(526-528)GTG>ATG	p.V176M	KCNJ6_uc002ywo.2_Missense_Mutation_p.V176M	NM_002240	NP_002231	P48051	IRK6_HUMAN	potassium inwardly-rectifying channel J6	176	Helical; Name=M2; (By similarity).				synaptic transmission	Golgi apparatus|voltage-gated potassium channel complex	G-protein activated inward rectifier potassium channel activity|protein binding			skin(1)	1					Halothane(DB01159)	GACCCCAACACAGATTGGATT	0.433000												
MCM3AP	8888	broad.mit.edu	37	21	47664820	47664820	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr21:47664820G>A	uc002zir.1	-	23	4975	c.4939C>T	c.(4939-4941)CTT>TTT	p.L1647F	MCM3APAS_uc002zim.2_Intron|MCM3APAS_uc002zin.2_Intron|MCM3AP_uc002zio.1_Missense_Mutation_p.L142F|MCM3AP_uc002zip.1_Missense_Mutation_p.L388F|MCM3AP_uc002ziq.1_Missense_Mutation_p.L574F|MCM3APAS_uc002zis.1_Intron	NM_003906	NP_003897	O60318	MCM3A_HUMAN	minichromosome maintenance complex component 3	1647					DNA replication|protein import into nucleus	cytosol|nucleus	DNA binding|nucleotide binding			large_intestine(2)|lung(1)|ovary(1)|skin(1)	5	Breast(49;0.112)					AGGTGAGGAAGCAGCCGGCTG	0.632000												
SUSD2	56241	broad.mit.edu	37	22	24583266	24583266	+	Missense_Mutation	SNP	T	T	G			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr22:24583266T>G	uc002zzn.1	+	11	1783	c.1739T>G	c.(1738-1740)GTG>GGG	p.V580G		NM_019601	NP_062547	Q9UGT4	SUSD2_HUMAN	sushi domain containing 2 precursor	580	VWFD.|Extracellular (Potential).				immune response	integral to membrane	polysaccharide binding|protein binding|scavenger receptor activity			skin(1)	1						TTCCTGAGTGTGTCCGTCCTG	0.662000												
ACO2	50	broad.mit.edu	37	22	41923306	41923306	+	Silent	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr22:41923306G>A	uc003bac.2	+	16	1990	c.1968G>A	c.(1966-1968)AGG>AGA	p.R656R	ACO2_uc003bad.2_Silent_p.R681R|POLR3H_uc003bae.2_RNA|POLR3H_uc003baf.2_3'UTR|POLR3H_uc003bag.2_3'UTR|POLR3H_uc003bai.2_3'UTR	NM_001098	NP_001089	Q99798	ACON_HUMAN	aconitase 2, mitochondrial precursor	656					citrate metabolic process|tricarboxylic acid cycle	mitochondrial matrix|nucleus	4 iron, 4 sulfur cluster binding|aconitate hydratase activity|citrate hydro-lyase (cis-aconitate-forming) activity|iron ion binding|isocitrate hydro-lyase (cis-aconitate-forming) activity			breast(2)|ovary(1)|lung(1)	4						ATGGCATCAGGTGGGTGGTGA	0.637000											OREG0026589	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)
PKDREJ	10343	broad.mit.edu	37	22	46658193	46658193	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr22:46658193C>T	uc003bhh.2	-	1	1027	c.1027G>A	c.(1027-1029)GAT>AAT	p.D343N		NM_006071	NP_006062	Q9NTG1	PKDRE_HUMAN	receptor for egg jelly-like protein precursor	343	Extracellular (Potential).|REJ.				acrosome reaction|neuropeptide signaling pathway	integral to membrane	calcium ion binding|ion channel activity			breast(3)|ovary(2)	5		Ovarian(80;0.00965)|all_neural(38;0.0416)		UCEC - Uterine corpus endometrioid carcinoma (28;0.00459)		ATGTTGGCATCGCCAAGCATC	0.572000												
CNTN6	27255	broad.mit.edu	37	3	1337484	1337484	+	Silent	SNP	T	T	G			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr3:1337484T>G	uc003boz.2	+	6	921	c.654T>G	c.(652-654)ACT>ACG	p.T218T	CNTN6_uc010hbo.2_Silent_p.T213T|CNTN6_uc011asj.1_Silent_p.T146T|CNTN6_uc003bpa.2_Silent_p.T218T	NM_014461	NP_055276	Q9UQ52	CNTN6_HUMAN	contactin 6 precursor	218					axon guidance|cell adhesion|central nervous system development|Notch signaling pathway	anchored to membrane|plasma membrane				skin(3)|lung(2)|breast(2)|pancreas(1)	8		all_cancers(2;0.000164)|all_epithelial(2;0.107)		Epithelial(13;0.000233)|all cancers(10;0.0013)|OV - Ovarian serous cystadenocarcinoma(96;0.0139)		TGCAGCGCACTGATGGTAAGA	0.438000												
CACNA2D3	55799	broad.mit.edu	37	3	54871251	54871251	+	Silent	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr3:54871251C>T	uc003dhf.2	+	15	1512	c.1464C>T	c.(1462-1464)AAC>AAT	p.N488N	CACNA2D3_uc011beu.1_RNA|CACNA2D3_uc003dhg.1_Silent_p.N394N|CACNA2D3_uc003dhh.1_RNA|CACNA2D3_uc010hmv.1_Silent_p.N222N	NM_018398	NP_060868	Q8IZS8	CA2D3_HUMAN	calcium channel, voltage-dependent, alpha	488	Extracellular (Potential).|Cache.					integral to membrane	calcium channel activity|metal ion binding|voltage-gated ion channel activity			large_intestine(3)|ovary(1)|breast(1)|central_nervous_system(1)|skin(1)	7				KIRC - Kidney renal clear cell carcinoma(284;0.00287)|Kidney(284;0.00327)		GTAAGCAGAACGAAACCGTGA	0.517000												
C3orf52	79669	broad.mit.edu	37	3	111828417	111828417	+	Missense_Mutation	SNP	T	T	G			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr3:111828417T>G	uc003dyq.3	+	4	497	c.424T>G	c.(424-426)TCT>GCT	p.S142A	C3orf52_uc011bhs.1_Intron|C3orf52_uc011bht.1_Intron|C3orf52_uc003dyr.1_5'Flank	NM_024616	NP_078892	Q5BVD1	TTMP_HUMAN	TPA-induced transmembrane protein	142						endoplasmic reticulum membrane|integral to membrane					0						TACATCGCCCTCTCTGGGTCG	0.413000												
PODXL2	50512	broad.mit.edu	37	3	127381088	127381088	+	Nonsense_Mutation	SNP	C	C	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr3:127381088C>A	uc003ejq.2	+	4	1164	c.1140C>A	c.(1138-1140)TGC>TGA	p.C380*		NM_015720	NP_056535	Q9NZ53	PDXL2_HUMAN	podocalyxin-like 2 precursor	380	Extracellular (Potential).				leukocyte tethering or rolling	integral to plasma membrane	glycosaminoglycan binding|protein binding			ovary(1)|central_nervous_system(1)	2						AGGTGATCTGCAAGGACTGGA	0.547000												
RASGEF1B	153020	broad.mit.edu	37	4	82355019	82355019	+	Silent	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr4:82355019G>A	uc003hmi.1	-	12	1443	c.1299C>T	c.(1297-1299)CTC>CTT	p.L433L	RASGEF1B_uc003hmj.1_Silent_p.L432L|RASGEF1B_uc010ijq.1_Silent_p.L391L	NM_152545	NP_689758	Q0VAM2	RGF1B_HUMAN	RasGEF domain family, member 1B	433	Ras-GEF.				regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	intracellular	Ras guanyl-nucleotide exchange factor activity				0						CTGGTACTGTGAGCAGATACT	0.423000												
HNRNPA0	10949	broad.mit.edu	37	5	137089636	137089636	+	Silent	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr5:137089636C>T	uc003lbt.2	-	1	404	c.120G>A	c.(118-120)GTG>GTA	p.V40V	MYOT_uc011cye.1_Intron|HNRNPA0_uc010jeo.2_Intron	NM_006805	NP_006796	Q13151	ROA0_HUMAN	heterogeneous nuclear ribonucleoprotein A0	40	RRM 1.				nuclear mRNA splicing, via spliceosome	heterogeneous nuclear ribonucleoprotein complex|nucleoplasm	nucleotide binding|RNA binding				0			KIRC - Kidney renal clear cell carcinoma(527;0.0101)|Kidney(363;0.0233)			TCTGGGGATTCACCACCACCA	0.642000												
GRIA1	2890	broad.mit.edu	37	5	153030042	153030042	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr5:153030042G>A	uc003lva.3	+	4	978	c.613G>A	c.(613-615)GAA>AAA	p.E205K	GRIA1_uc003luy.3_Missense_Mutation_p.E205K|GRIA1_uc003luz.3_Missense_Mutation_p.E110K|GRIA1_uc011dcv.1_RNA|GRIA1_uc011dcw.1_Missense_Mutation_p.E125K|GRIA1_uc011dcx.1_Missense_Mutation_p.E136K|GRIA1_uc011dcy.1_Missense_Mutation_p.E215K|GRIA1_uc011dcz.1_Missense_Mutation_p.E215K|GRIA1_uc010jia.1_Missense_Mutation_p.E185K	NM_001114183	NP_001107655	P42261	GRIA1_HUMAN	glutamate receptor, ionotropic, AMPA 1 isoform	205	Extracellular (Potential).				synaptic transmission	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|cell junction|dendritic spine|endocytic vesicle membrane|endoplasmic reticulum membrane|neuronal cell body|postsynaptic density|postsynaptic membrane	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|extracellular-glutamate-gated ion channel activity|kainate selective glutamate receptor activity|PDZ domain binding			ovary(4)|skin(2)	6		Medulloblastoma(196;0.0391)|all_neural(177;0.16)|all_hematologic(541;0.21)	Kidney(363;0.000173)|KIRC - Kidney renal clear cell carcinoma(527;0.000785)		Desflurane(DB01189)|Enflurane(DB00228)|Halothane(DB01159)|Isoflurane(DB00753)|L-Glutamic Acid(DB00142)|Methoxyflurane(DB01028)|Sevoflurane(DB01236)	GGTGGACTGTGAATCAGAACG	0.532000												
FLT4	2324	broad.mit.edu	37	5	180040051	180040051	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr5:180040051C>T	uc003mma.3	-	25	3470	c.3391G>A	c.(3391-3393)GGC>AGC	p.G1131S	FLT4_uc003mlz.3_Missense_Mutation_p.G1131S	NM_002020	NP_002011	P35916	VGFR3_HUMAN	fms-related tyrosine kinase 4 isoform 2	1131	Cytoplasmic (Potential).|Protein kinase.				positive regulation of cell proliferation	integral to plasma membrane	ATP binding|protein phosphatase binding|vascular endothelial growth factor receptor activity			lung(7)|skin(2)|ovary(2)|stomach(1)|central_nervous_system(1)|breast(1)|kidney(1)	15	all_cancers(89;2.21e-05)|all_epithelial(37;5.29e-06)|Renal(175;0.000159)|Lung NSC(126;0.00199)|all_lung(126;0.00351)|Breast(19;0.114)	all_cancers(40;0.00245)|Medulloblastoma(196;0.0133)|all_neural(177;0.0199)|all_hematologic(541;0.163)|Ovarian(839;0.238)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)	all cancers(165;0.134)	Sorafenib(DB00398)|Sunitinib(DB01268)	ATCCTTGTGCCGTCTCTCAGC	0.667000									Congenital_Hereditary_Lymphedema			
HIST1H2AC	8334	broad.mit.edu	37	6	26124688	26124688	+	Missense_Mutation	SNP	G	G	C			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr6:26124688G>C	uc003ngm.2	+	1	316	c.228G>C	c.(226-228)AAG>AAC	p.K76N	HIST1H2BC_uc003ngk.3_5'Flank|HIST1H2BC_uc003ngl.2_5'Flank|HIST1H2AC_uc003ngn.2_RNA|HIST1H2AC_uc003ngo.2_RNA|HIST1H2AC_uc003ngp.2_Missense_Mutation_p.K76N	NM_003512	NP_003503	Q93077	H2A1C_HUMAN	histone cluster 1, H2ac	76					nucleosome assembly	nucleosome|nucleus	DNA binding				0						ACAACAAGAAGACTCGCATCA	0.657000												
HIST1H2AM	8336	broad.mit.edu	37	6	27860703	27860703	+	Silent	SNP	T	T	C			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr6:27860703T>C	uc003nkb.1	-	1	261	c.225A>G	c.(223-225)AAA>AAG	p.K75K	HIST1H3J_uc003nka.2_5'Flank|HIST1H2BO_uc003nkc.1_5'Flank	NM_003514	NP_003505	P0C0S8	H2A1_HUMAN	histone cluster 1, H2am	75					nucleosome assembly	nucleosome|nucleus	DNA binding|enzyme binding			ovary(2)	2						TGCGGGTCTTTTTGTTGTCGC	0.642000												
LRFN2	57497	broad.mit.edu	37	6	40359893	40359893	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr6:40359893C>T	uc003oph.1	-	3	2624	c.2159G>A	c.(2158-2160)CGC>CAC	p.R720H		NM_020737	NP_065788	Q9ULH4	LRFN2_HUMAN	leucine rich repeat and fibronectin type III	720	Cytoplasmic (Potential).					cell junction|integral to membrane|postsynaptic membrane				ovary(2)|skin(1)	3	Ovarian(28;0.0418)|Colorectal(47;0.196)					GGAGTGGCTGCGTTTGGCCTT	0.711000												
AUTS2	26053	broad.mit.edu	37	7	70231198	70231198	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr7:70231198G>A	uc003tvw.3	+	9	2310	c.1567G>A	c.(1567-1569)GAG>AAG	p.E523K	AUTS2_uc003tvx.3_Missense_Mutation_p.E523K|AUTS2_uc011keg.1_5'Flank	NM_015570	NP_056385	Q8WXX7	AUTS2_HUMAN	autism susceptibility candidate 2 isoform 1	523										ovary(2)|central_nervous_system(1)	3		all_cancers(73;0.0264)|all_epithelial(88;0.0198)|Lung NSC(55;0.0599)|all_lung(88;0.093)		LUSC - Lung squamous cell carcinoma(90;0.082)|Lung(90;0.186)		CCTGCGGACCGAGTTCCATca	0.463000												
PCLO	27445	broad.mit.edu	37	7	82764926	82764926	+	Missense_Mutation	SNP	C	C	G			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr7:82764926C>G	uc003uhx.2	-	3	2229	c.1940G>C	c.(1939-1941)GGC>GCC	p.G647A	PCLO_uc003uhv.2_Missense_Mutation_p.G647A	NM_033026	NP_149015	Q9Y6V0	PCLO_HUMAN	piccolo isoform 1	593	Pro-rich.				cytoskeleton organization|synaptic vesicle exocytosis	cell junction|cytoskeleton|synaptic vesicle	calcium ion binding|calcium-dependent phospholipid binding|profilin binding|transporter activity			ovary(7)	7						CAGATCCCCGCCTAGAGCTCT	0.448000												
PTPRN2	5799	broad.mit.edu	37	7	157414082	157414082	+	Silent	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr7:157414082G>A	uc003wno.2	-	15	2437	c.2316C>T	c.(2314-2316)CCC>CCT	p.P772P	PTPRN2_uc003wnp.2_Silent_p.P755P|PTPRN2_uc003wnq.2_Silent_p.P743P|PTPRN2_uc003wnr.2_Silent_p.P734P|PTPRN2_uc011kwa.1_Silent_p.P795P	NM_002847	NP_002838	Q92932	PTPR2_HUMAN	protein tyrosine phosphatase, receptor type, N	772	Cytoplasmic (Potential).|Tyrosine-protein phosphatase.					integral to plasma membrane	protein binding|transmembrane receptor protein tyrosine phosphatase activity			ovary(4)|large_intestine(1)|pleura(1)|skin(1)	7	all_neural(206;0.181)	all_cancers(7;8.99e-13)|all_epithelial(9;2.4e-06)|all_hematologic(28;0.0155)|Breast(660;0.132)	OV - Ovarian serous cystadenocarcinoma(82;0.00463)	STAD - Stomach adenocarcinoma(7;0.0875)		AGCGGTTCTTGGGCACGTTCT	0.637000												
LZTS1	11178	broad.mit.edu	37	8	20110556	20110556	+	Missense_Mutation	SNP	C	C	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr8:20110556C>T	uc003wzr.2	-	2	997	c.886G>A	c.(886-888)GAG>AAG	p.E296K	LZTS1_uc010ltg.1_Missense_Mutation_p.E296K	NM_021020	NP_066300	Q9Y250	LZTS1_HUMAN	leucine zipper, putative tumor suppressor 1	296	Potential.				cell cycle|termination of RNA polymerase III transcription|transcription elongation from RNA polymerase III promoter	cell junction|dendritic spine|Golgi apparatus|nucleolus|nucleoplasm|postsynaptic density|postsynaptic membrane	DNA binding|protein binding|sequence-specific DNA binding transcription factor activity			ovary(1)	1				Colorectal(74;0.0511)|COAD - Colon adenocarcinoma(73;0.207)		GGCCGCTCCTCGTAGGCCAGG	0.677000												
ASAP1	50807	broad.mit.edu	37	8	131088602	131088602	+	Missense_Mutation	SNP	G	G	T			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr8:131088602G>T	uc003yta.1	-	26	2721	c.2693C>A	c.(2692-2694)CCT>CAT	p.P898H	ASAP1_uc003ysz.1_Missense_Mutation_p.P709H|ASAP1_uc011liw.1_Missense_Mutation_p.P891H	NM_018482	NP_060952	Q9ULH1	ASAP1_HUMAN	development and differentiation enhancing factor	898	Pro-rich.				cilium morphogenesis|filopodium assembly|regulation of ARF GTPase activity|signal transduction	cytoplasm|membrane	ARF GTPase activator activity|cytoskeletal adaptor activity|SH3 domain binding|zinc ion binding			ovary(4)	4						ACCTTTCTGAGGTAGTTTAGG	0.284000												
ARHGAP39	80728	broad.mit.edu	37	8	145773557	145773557	+	Missense_Mutation	SNP	G	G	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr8:145773557G>A	uc003zdt.1	-	6	1468	c.913C>T	c.(913-915)CGC>TGC	p.R305C	ARHGAP39_uc011llk.1_Missense_Mutation_p.R305C|ARHGAP39_uc003zds.1_Missense_Mutation_p.R305C	NM_025251	NP_079527	Q9C0H5	RHG39_HUMAN	KIAA1688 protein	305	Pro-rich.				axon guidance|regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	cytoskeleton|cytosol|nucleus	GTPase activator activity				0						TAGCCATAGCGCGGGGAGGAG	0.692000												
PHF2	5253	broad.mit.edu	37	9	96438029	96438029	+	Silent	SNP	C	C	T	rs148663364		TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr9:96438029C>T	uc004aub.2	+	20	2937	c.2790C>T	c.(2788-2790)ATC>ATT	p.I930I	PHF2_uc011lug.1_Silent_p.I813I|PHF2_uc004auc.2_Silent_p.I350I	NM_005392	NP_005383	O75151	PHF2_HUMAN	PHD finger protein 2	930					liver development|negative regulation of chromatin silencing at rDNA|transcription, DNA-dependent	nucleolus	histone demethylase activity (H3-K9 specific)|iron ion binding|methylated histone residue binding|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|zinc ion binding			ovary(1)	1		Myeloproliferative disorder(762;0.0255)		OV - Ovarian serous cystadenocarcinoma(323;9.11e-28)		TGGCTTCCATCGAGACCGGGC	0.657000												
OR5C1	392391	broad.mit.edu	37	9	125551994	125551994	+	Missense_Mutation	SNP	C	C	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr9:125551994C>A	uc011lzd.1	+	1	783	c.783C>A	c.(781-783)TTC>TTA	p.F261L		NM_001001923	NP_001001923	Q8NGR4	OR5C1_HUMAN	olfactory receptor, family 5, subfamily C,	261	Helical; Name=6; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			pancreas(1)	1						CACTCATTTTCATGTACCTGC	0.587000												
CYLC1	1538	broad.mit.edu	37	X	83128123	83128123	+	Missense_Mutation	SNP	G	G	C			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chrX:83128123G>C	uc004eei.1	+	4	428	c.407G>C	c.(406-408)GGT>GCT	p.G136A	CYLC1_uc004eeh.1_Missense_Mutation_p.G135A	NM_021118	NP_066941	P35663	CYLC1_HUMAN	cylicin, basic protein of sperm head	136					cell differentiation|multicellular organismal development|spermatogenesis	acrosomal matrix|cytoskeletal calyx	structural molecule activity			ovary(4)|skin(1)	5						AAAAAAGGAGGTTCATATGCA	0.318000												
ARHGEF16	27237	broad.mit.edu	37	1	3396111	3396112	+	Frame_Shift_Del	DEL	CA	CA	-			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr1:3396111_3396112delCA	uc001akg.3	+	13	2093_2094	c.1845_1846delCA	c.(1843-1848)CTCACAfs	p.L615fs	ARHGEF16_uc001aki.2_Frame_Shift_Del_p.L327fs|ARHGEF16_uc001akj.2_Frame_Shift_Del_p.L327fs|ARHGEF16_uc010nzh.1_Frame_Shift_Del_p.L319fs	NM_014448	NP_055263	Q5VV41	ARHGG_HUMAN	Rho guanine exchange factor 16	615_616	PH.				activation of Cdc42 GTPase activity|activation of Rac GTPase activity|apoptosis|cell chemotaxis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|positive regulation of establishment of protein localization in plasma membrane|small GTPase mediated signal transduction	cytosol	PDZ domain binding|receptor tyrosine kinase binding|Rho GTPase binding|Rho guanyl-nucleotide exchange factor activity			ovary(1)	1	all_cancers(77;0.00276)|all_epithelial(69;0.00102)|Ovarian(185;0.0634)|Lung NSC(156;0.0969)|all_lung(157;0.101)	all_epithelial(116;7.14e-21)|all_lung(118;2.24e-08)|Lung NSC(185;3.55e-06)|Breast(487;0.000765)|Renal(390;0.00121)|Hepatocellular(190;0.0046)|Myeloproliferative disorder(586;0.0255)|Ovarian(437;0.0308)|Lung SC(97;0.0847)|Medulloblastoma(700;0.211)		Epithelial(90;8.62e-38)|OV - Ovarian serous cystadenocarcinoma(86;3.62e-22)|GBM - Glioblastoma multiforme(42;2.49e-12)|Colorectal(212;4.25e-05)|COAD - Colon adenocarcinoma(227;0.000196)|Kidney(185;0.000342)|BRCA - Breast invasive adenocarcinoma(365;0.000681)|KIRC - Kidney renal clear cell carcinoma(229;0.00549)|STAD - Stomach adenocarcinoma(132;0.00644)|Lung(427;0.201)		TCGTGGCGCTCACACACAGTGA	0.653												
C16orf11	146325	broad.mit.edu	37	16	614731	614731	+	Frame_Shift_Del	DEL	T	T	-			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr16:614731delT	uc002chk.2	+	3	1419	c.1140delT	c.(1138-1140)CCTfs	p.P380fs	NHLRC4_uc002chl.2_5'Flank|PIGQ_uc010bqw.2_5'Flank	NM_145270	NP_660313	P0CG20	CP011_HUMAN	hypothetical protein LOC146325	380	Pro-rich.									central_nervous_system(1)	1						CAGGCGGCCCTGAGACCCCCG	0.731												
OR5H2	79310	broad.mit.edu	37	3	98001984	98001985	+	Frame_Shift_Ins	INS	-	-	A			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr3:98001983_98001984C>CA	uc003dsj.1	+	0	252_253	c.252_253C>CA	c.(250-255)cccaaafs	p.P84fs		NM_001005482	NP_001005482	Q8NGV7	OR5H2_HUMAN	Homo sapiens olfactory receptor, family 5, subfamily H, member 2 (OR5H2), mRNA.	84					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity	p.P84P(2)		breast(1)|endometrium(1)|large_intestine(5)|lung(13)|ovary(3)|upper_aerodigestive_tract(1)	24						CAGTAACTCCCAAAATGTTGGT	0.376												
GALNTL4	374378	broad.mit.edu	37	11	11400693	11400716	+	In_Frame_Del	DEL	GCCACTGACCCTGGAGCGGATGAG	GCCACTGACCCTGGAGCGGATGAG	-			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr11:11400692_11400715AGCCACTGACCCTGGAGCGGATGAG>A	uc001mjo.2	-	3	1113_1136	c.692_715CTCATCCGCTCCAGGGTCAGTGGCT>T	c.(691-717)ctcatccgctccagggtcagtggctgg>cTgg	p.IRSRVSGW232del		NM_198516	NP_940918	Q6P9A2	GLTL4_HUMAN	Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4 (GALNTL4), mRNA.	232	Catalytic subdomain A.					Golgi membrane|integral to membrane	polypeptide N-acetylgalactosaminyltransferase activity|sugar binding			autonomic_ganglia(1)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(6)|lung(11)|prostate(1)|skin(1)|stomach(1)|urinary_tract(1)	26				all cancers(16;3.67e-05)|Epithelial(150;0.000184)		GCCGCCCTCCAGCCACTGACCCTGGAGCGGATGAGGCCTTCCTG	0.585												
NUP107	57122	broad.mit.edu	37	12	69096558	69096558	+	Frame_Shift_Del	DEL	A	A	-			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr12:69096557_69096557CA>C	uc001suf.3	+	7	837	c.722_722CA>C	c.(721-723)gcafs	p.A241fs	NUP107_uc001sug.3_Frame_Shift_Del_p.A88fs|NUP107_uc010stj.2_Frame_Shift_Del_p.A212fs	NM_020401	NP_065134	P57740	NU107_HUMAN	Homo sapiens nucleoporin 107kDa (NUP107), mRNA.	241					carbohydrate metabolic process|glucose transport|mRNA export from nucleus|mitotic prometaphase|protein transport|regulation of glucose transport|transmembrane transport|viral reproduction	Nup107-160 complex|condensed chromosome kinetochore|cytosol	nucleocytoplasmic transporter activity|protein binding		NUP107/LGR5(2)	breast(3)|endometrium(4)|kidney(4)|large_intestine(12)|lung(11)|prostate(1)|skin(2)|urinary_tract(2)	39	Breast(13;6.25e-06)		Lung(24;0.000131)|LUAD - Lung adenocarcinoma(15;0.00107)|STAD - Stomach adenocarcinoma(21;0.00694)			AGTGTATTCGCAGTTACTGTA	0.274												
BAZ1A	11177	broad.mit.edu	37	14	35343708	35343708	+	Frame_Shift_Del	DEL	G	G	-			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr14:35343707_35343707CG>C	uc001wsk.3	-	1	672	c.104_104CG>G	c.(103-105)cgcfs	p.R35fs	BAZ1A_uc001wsl.3_Frame_Shift_Del_p.R35fs|BAZ1A_uc001wsm.1_Frame_Shift_Del_p.R35fs	NM_013448	NP_038476	Q9NRL2	BAZ1A_HUMAN	Homo sapiens bromodomain adjacent to zinc finger domain, 1A (BAZ1A), transcript variant 1, mRNA.	35	Required for association with the CHRAC1/POLE3 complex.|Required for interaction with NCOR1.|WAC.				chromatin remodeling|regulation of transcription, DNA-dependent|transcription, DNA-dependent	ACF complex	zinc ion binding			breast(2)|central_nervous_system(2)|cervix(2)|endometrium(6)|kidney(2)|large_intestine(7)|lung(19)|ovary(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	48	Breast(36;0.0388)|Hepatocellular(127;0.158)		LUAD - Lung adenocarcinoma(48;7.23e-05)|Lung(238;0.00019)|Epithelial(34;0.0793)|all cancers(34;0.175)	GBM - Glioblastoma multiforme(112;0.0659)		CTCGTAGTGGCGGAAGATCTC	0.637												
PPP1R13B	23368	broad.mit.edu	37	14	104251213	104251245	+	In_Frame_Del	DEL	GATGTTCGTACATCATATGATCAAAGGGTATGG	GATGTTCGTACATCATATGATCAAAGGGTATGG	-			TCGA-CG-4304-01A-01D-1158-08	TCGA-CG-4304-10A-01D-1158-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fb2c02fb-8044-4ead-b526-a4967c300a77	515dd0bb-8739-48bb-bc81-b3d40f6992cb	g.chr14:104251212_104251244AGATGTTCGTACATCATATGATCAAAGGGTATGG>A	uc001yof.1	-	2	448_480	c.165_197CCATACCCTTTGATCATATGATGTACGAACATCT>T	c.(163-198)cccataccctttgatcatatgatgtacgaacatctt>ccTt	p.IPFDHMMYEHL56del	PPP1R13B_uc001yog.1_5'UTR	NM_015316	NP_056131	Q96KQ4	ASPP1_HUMAN	Homo sapiens protein phosphatase 1, regulatory subunit 13B (PPP1R13B), mRNA.	56					apoptosis|induction of apoptosis|negative regulation of cell cycle	cytoplasm|nucleus|plasma membrane	protein binding	p.E64*(2)|p.P57P(2)|p.M61I(2)		endometrium(6)|kidney(2)|large_intestine(7)|lung(16)|ovary(1)|upper_aerodigestive_tract(1)	33		all_cancers(154;0.173)|all_epithelial(191;0.131)|Melanoma(154;0.155)				CCATTTCTGAAGATGTTCGTACATCATATGATCAAAGGGTATGGGACGTTCTA	0.378