Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values
CCNL2	81669	broad.mit.edu	37	1	1330804	1330804	+	Silent	SNP	A	A	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr1:1330804A>C	uc001afi.2	-	4	596	c.564T>G	c.(562-564)GGT>GGG	p.G188G	CCNL2_uc001aff.1_5'Flank|CCNL2_uc001afg.1_5'UTR|CCNL2_uc001afh.2_Silent_p.G188G|CCNL2_uc001afj.2_Silent_p.G188G|CCNL2_uc001afk.2_Silent_p.G188G	NM_030937	NP_112199	Q96S94	CCNL2_HUMAN	cyclin L2 isoform A	188					regulation of cyclin-dependent protein kinase activity|regulation of transcription, DNA-dependent|RNA processing|transcription, DNA-dependent	nuclear speck	protein kinase binding			ovary(2)|central_nervous_system(1)	3	all_cancers(77;0.00164)|all_epithelial(69;0.000959)|all_lung(157;0.00963)|Lung NSC(156;0.0232)|Ovarian(185;0.0634)	all_epithelial(116;8.75e-19)|all_lung(118;2.3e-08)|Lung NSC(185;2.38e-06)|Renal(390;0.00183)|Breast(487;0.00354)|Hepatocellular(190;0.00826)|Myeloproliferative disorder(586;0.0122)|Ovarian(437;0.0308)|Lung SC(97;0.128)		Epithelial(90;2.03e-36)|OV - Ovarian serous cystadenocarcinoma(86;4.17e-22)|Colorectal(212;0.000159)|COAD - Colon adenocarcinoma(227;0.000193)|Kidney(185;0.0023)|BRCA - Breast invasive adenocarcinoma(365;0.00465)|STAD - Stomach adenocarcinoma(132;0.00644)|KIRC - Kidney renal clear cell carcinoma(229;0.0342)|Lung(427;0.146)		GGACGCAGAAACCCAACTCTT	0.537000												
CELA2A	63036	broad.mit.edu	37	1	15789355	15789355	+	Missense_Mutation	SNP	G	G	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr1:15789355G>T	uc001awk.2	+	4	381	c.355G>T	c.(355-357)GGG>TGG	p.G119W		NM_033440	NP_254275	P08217	CEL2A_HUMAN	elastase 2A preproprotein	119	Peptidase S1.				proteolysis	extracellular region	serine-type endopeptidase activity			ovary(2)	2						AATCTCCAAAGGGTTCGTTTC	0.577000												
MAP7D1	55700	broad.mit.edu	37	1	36642154	36642154	+	Missense_Mutation	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr1:36642154C>T	uc001bzz.2	+	7	1421	c.1205C>T	c.(1204-1206)CCG>CTG	p.P402L	MAP7D1_uc001caa.2_Missense_Mutation_p.P370L|MAP7D1_uc001cab.2_Missense_Mutation_p.P365L|MAP7D1_uc001cac.2_Missense_Mutation_p.P102L|MAP7D1_uc001cad.2_5'Flank	NM_018067	NP_060537	Q3KQU3	MA7D1_HUMAN	MAP7 domain containing 1	402						cytoplasm|spindle				ovary(3)|breast(2)	5		Myeloproliferative disorder(586;0.0393)				AGCCCCGCTCCGGTGCGCCGC	0.781000												
MRPS15	64960	broad.mit.edu	37	1	36929865	36929865	+	Silent	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr1:36929865G>A	uc001cas.2	-	1	176	c.12C>T	c.(10-12)GTC>GTT	p.V4V		NM_031280	NP_112570	P82914	RT15_HUMAN	mitochondrial ribosomal protein S15 precursor	4					translation	mitochondrial small ribosomal subunit|nuclear membrane	structural constituent of ribosome			ovary(1)	1		Myeloproliferative disorder(586;0.0255)|all_neural(195;0.164)				TCCTCCACGCGACCCTCAGCA	0.542000												
OMA1	115209	broad.mit.edu	37	1	59004914	59004914	+	Missense_Mutation	SNP	C	C	G			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr1:59004914C>G	uc001cyy.2	-	2	141	c.53G>C	c.(52-54)CGA>CCA	p.R18P	DAB1_uc001cyt.1_Intron|OMA1_uc001cyx.1_Missense_Mutation_p.R18P|OMA1_uc009vzz.2_Missense_Mutation_p.R18P	NM_145243	NP_660286	Q96E52	OMA1_HUMAN	OMA1 homolog, zinc metallopeptidase precursor	18					proteolysis	integral to membrane|mitochondrial membrane	metal ion binding|metalloendopeptidase activity			large_intestine(1)	1	all_cancers(7;6.54e-05)					TGAATTAAATCGGAAGAAAAC	0.358000												
HRNR	388697	broad.mit.edu	37	1	152192120	152192120	+	Missense_Mutation	SNP	C	C	T	rs146400284	byFrequency	TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr1:152192120C>T	uc001ezt.1	-	3	2061	c.1985G>A	c.(1984-1986)CGC>CAC	p.R662H		NM_001009931	NP_001009931	Q86YZ3	HORN_HUMAN	hornerin	662	6.				keratinization		calcium ion binding|protein binding			skin(2)|ovary(1)	3	Hepatocellular(266;0.0877)|Melanoma(130;0.116)|all_hematologic(923;0.127)		LUSC - Lung squamous cell carcinoma(543;0.206)			ATGTCGGCCGCGACTAGGAGA	0.587000												
IGSF9	57549	broad.mit.edu	37	1	159901336	159901336	+	Nonsense_Mutation	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr1:159901336G>A	uc001fur.2	-	12	1618	c.1420C>T	c.(1420-1422)CGA>TGA	p.R474*	IGSF9_uc001fuq.2_Nonsense_Mutation_p.R458*|IGSF9_uc001fup.2_5'UTR	NM_001135050	NP_001128522	Q9P2J2	TUTLA_HUMAN	immunoglobulin superfamily, member 9 isoform a	474	Ig-like 5.|Extracellular (Potential).					cell junction|integral to membrane|synapse				ovary(2)|central_nervous_system(2)|large_intestine(1)	5	all_hematologic(112;0.0597)	Breast(1374;0.000126)	BRCA - Breast invasive adenocarcinoma(70;0.111)			GTCAATGGTCGCAGGATGAGG	0.647000												
KIAA1462	57608	broad.mit.edu	37	10	30336633	30336633	+	Missense_Mutation	SNP	T	T	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr10:30336633T>C	uc001iux.2	-	1	168	c.109A>G	c.(109-111)ACA>GCA	p.T37A	KIAA1462_uc001iuy.2_Missense_Mutation_p.T37A|KIAA1462_uc001iuz.2_5'UTR|KIAA1462_uc009xle.1_Missense_Mutation_p.T37A	NM_020848	NP_065899	Q9P266	K1462_HUMAN	hypothetical protein LOC57608	37										ovary(4)	4						CCTGCTCGTGTCCCAGTCCTC	0.617000												
SLIT1	6585	broad.mit.edu	37	10	98778863	98778863	+	Silent	SNP	A	A	G			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr10:98778863A>G	uc001kmw.2	-	27	3000	c.2748T>C	c.(2746-2748)GGT>GGC	p.G916G		NM_003061	NP_003052	O75093	SLIT1_HUMAN	slit homolog 1 precursor	916	LRRCT 4.				axon extension involved in axon guidance|forebrain morphogenesis|motor axon guidance|negative chemotaxis|negative regulation of synaptogenesis	cytoplasm|extracellular space	calcium ion binding|Roundabout binding			ovary(4)	4		Colorectal(252;0.162)		Epithelial(162;2.02e-08)|all cancers(201;1.5e-06)		GCGTTGGAGGACCTGCAGCAA	0.632000												
ATRNL1	26033	broad.mit.edu	37	10	117040941	117040941	+	Missense_Mutation	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr10:117040941C>T	uc001lcg.2	+	14	2563	c.2177C>T	c.(2176-2178)TCA>TTA	p.S726L		NM_207303	NP_997186	Q5VV63	ATRN1_HUMAN	attractin-like 1 precursor	726	PSI 3.|Extracellular (Potential).					integral to membrane	sugar binding			ovary(5)|lung(1)|central_nervous_system(1)	7		all_lung(145;0.0686)|Breast(234;0.0969)|Lung NSC(174;0.17)|Colorectal(252;0.234)		Epithelial(162;0.00031)|all cancers(201;0.000753)|LUSC - Lung squamous cell carcinoma(1;0.0515)|Lung(30;0.0827)		AAAAGCTGTTCACTAAACTTG	0.358000												
HBD	3045	broad.mit.edu	37	11	5254304	5254304	+	Missense_Mutation	SNP	C	C	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr11:5254304C>A	uc001maf.1	-	3	529	c.334G>T	c.(334-336)GTG>TTG	p.V112L		NM_000519	NP_000510	P02042	HBD_HUMAN	delta globin	112					blood coagulation	hemoglobin complex	heme binding|oxygen binding|oxygen transporter activity			ovary(1)	1		Medulloblastoma(188;0.00225)|Breast(177;0.0155)|all_neural(188;0.0212)		Epithelial(150;5.69e-10)|BRCA - Breast invasive adenocarcinoma(625;0.135)		AGCACACACACCAGCACATTG	0.522000												
C11orf49	79096	broad.mit.edu	37	11	46958381	46958381	+	Silent	SNP	C	C	T	rs142532345	byFrequency	TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr11:46958381C>T	uc001ndp.2	+	1	131	c.25C>T	c.(25-27)CTA>TTA	p.L9L	C11orf49_uc001nds.2_Silent_p.L9L|C11orf49_uc001ndq.2_Silent_p.L9L|C11orf49_uc001ndr.2_Silent_p.L9L|C11orf49_uc010rgx.1_5'UTR|C11orf49_uc010rgy.1_Missense_Mutation_p.P34L|C11orf49_uc010rgz.1_5'UTR	NM_024113	NP_077018	Q9H6J7	CK049_HUMAN	hypothetical protein LOC79096 isoform 3	9											0						GCGCCTAGCCCTACCGGACTA	0.617000												
OR6M1	390261	broad.mit.edu	37	11	123676616	123676616	+	Missense_Mutation	SNP	C	C	G			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr11:123676616C>G	uc010rzz.1	-	1	442	c.442G>C	c.(442-444)GTG>CTG	p.V148L		NM_001005325	NP_001005325	Q8NGM8	OR6M1_HUMAN	olfactory receptor, family 6, subfamily M,	148	Helical; Name=4; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			skin(2)	2		Breast(109;0.0109)|Medulloblastoma(222;0.0523)|Lung NSC(97;0.118)|all_lung(97;0.126)|all_neural(223;0.224)		BRCA - Breast invasive adenocarcinoma(274;4.88e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.028)		AAGGCTCCCACCCAGCATCCC	0.502000												
AKAP3	10566	broad.mit.edu	37	12	4747358	4747358	+	Missense_Mutation	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr12:4747358G>A	uc001qnb.3	-	3	234	c.5C>T	c.(4-6)TCA>TTA	p.S2L		NM_006422	NP_006413	O75969	AKAP3_HUMAN	A-kinase anchor protein 3	2					acrosome reaction|cellular component movement	acrosomal vesicle	protein kinase A binding			skin(3)|large_intestine(1)|ovary(1)|kidney(1)	6						AACCTTTTCTGACATCTGGAA	0.428000												
CLEC9A	283420	broad.mit.edu	37	12	10217429	10217429	+	Missense_Mutation	SNP	T	T	G			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr12:10217429T>G	uc001qxa.2	+	8	1183	c.570T>G	c.(568-570)GAT>GAG	p.D190E		NM_207345	NP_997228	Q6UXN8	CLC9A_HUMAN	C-type lectin domain family 9, member A	190	Extracellular (Potential).|C-type lectin.				positive regulation of cytokine secretion|receptor-mediated endocytosis	cell surface|integral to membrane	receptor activity|sugar binding			ovary(1)	1						TTTGGCAAGATGGCTCCTCTC	0.448000												
PDE3A	5139	broad.mit.edu	37	12	20522996	20522996	+	Missense_Mutation	SNP	C	C	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr12:20522996C>A	uc001reh.1	+	1	800	c.778C>A	c.(778-780)CCG>ACG	p.P260T		NM_000921	NP_000912	Q14432	PDE3A_HUMAN	phosphodiesterase 3A	260					lipid metabolic process|platelet activation|signal transduction	cytosol|integral to membrane	3',5'-cyclic-AMP phosphodiesterase activity|3',5'-cyclic-GMP phosphodiesterase activity|cGMP-inhibited cyclic-nucleotide phosphodiesterase activity|metal ion binding			ovary(3)|upper_aerodigestive_tract(1)	4	Esophageal squamous(101;0.125)	Breast(259;0.134)			Aminophylline(DB01223)|Amrinone(DB01427)|Anagrelide(DB00261)|Cilostazol(DB01166)|Enoximone(DB04880)|Milrinone(DB00235)|Theophylline(DB00277)	ACAAATCTTGCCGCAGTCCGC	0.597000												
KRT8	3856	broad.mit.edu	37	12	53292550	53292550	+	Missense_Mutation	SNP	C	C	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr12:53292550C>A	uc001sbd.2	-	6	1218	c.1115G>T	c.(1114-1116)CGT>CTT	p.R372L	KRT8_uc009zmj.2_Intron|KRT8_uc009zmk.1_Missense_Mutation_p.R400L|KRT8_uc009zml.1_Missense_Mutation_p.R372L|KRT8_uc009zmm.1_Missense_Mutation_p.R372L	NM_002273	NP_002264	P05787	K2C8_HUMAN	keratin 8	372	Necessary for interaction with PNN.|Rod.|Coil 2.				cytoskeleton organization|interspecies interaction between organisms	cytoplasm|keratin filament|nuclear matrix|nucleoplasm	protein binding|structural molecule activity			ovary(1)|skin(1)	2				BRCA - Breast invasive adenocarcinoma(357;0.108)	Alteplase(DB00009)|Anistreplase(DB00029)|Reteplase(DB00015)|Tenecteplase(DB00031)	CTGGTACTCACGCAGCTGCCG	0.642000												
CEP290	80184	broad.mit.edu	37	12	88478386	88478386	+	Missense_Mutation	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr12:88478386G>A	uc001tar.2	-	35	5025	c.4681C>T	c.(4681-4683)CGT>TGT	p.R1561C	CEP290_uc001taq.2_Missense_Mutation_p.R621C	NM_025114	NP_079390	O15078	CE290_HUMAN	centrosomal protein 290kDa	1561	Potential.				cilium assembly|eye photoreceptor cell development|G2/M transition of mitotic cell cycle|hindbrain development|otic vesicle formation|positive regulation of transcription, DNA-dependent|pronephros development|protein transport	cell surface|centrosome|cytosol|nucleus|photoreceptor connecting cilium	protein binding			ovary(5)|breast(1)|pancreas(1)	7						TCTAGAAGACGTTGATACTTC	0.299000												
CUX2	23316	broad.mit.edu	37	12	111758322	111758322	+	Missense_Mutation	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr12:111758322G>A	uc001tsa.1	+	17	2662	c.2509G>A	c.(2509-2511)GAG>AAG	p.E837K		NM_015267	NP_056082	O14529	CUX2_HUMAN	cut-like 2	837						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			ovary(3)|skin(2)|breast(1)	6						CCCCGAGGACGAGGCGGCGGC	0.776000												
CIT	11113	broad.mit.edu	37	12	120166313	120166313	+	Silent	SNP	C	C	G			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr12:120166313C>G	uc001txi.1	-	27	3512	c.3459G>C	c.(3457-3459)CTG>CTC	p.L1153L	CIT_uc001txh.1_Silent_p.L687L|CIT_uc001txj.1_Silent_p.L1195L	NM_007174	NP_009105	O14578	CTRO_HUMAN	citron	1153	Potential.|Interaction with Rho/Rac.				intracellular signal transduction		ATP binding|metal ion binding|protein serine/threonine kinase activity|SH3 domain binding|small GTPase regulator activity			ovary(6)|urinary_tract(1)|lung(1)|breast(1)|skin(1)	10	all_neural(191;0.0804)|Medulloblastoma(191;0.0922)	Myeloproliferative disorder(1001;0.0255)		BRCA - Breast invasive adenocarcinoma(302;0.211)		TCACCTCTTCCAGAAGCCTCT	0.353000												
TDRD3	81550	broad.mit.edu	37	13	61103082	61103082	+	Nonsense_Mutation	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr13:61103082C>T	uc001via.2	+	11	2232	c.1444C>T	c.(1444-1446)CAG>TAG	p.Q482*	TDRD3_uc010aef.2_Nonsense_Mutation_p.Q307*|TDRD3_uc001vhz.3_Nonsense_Mutation_p.Q482*|TDRD3_uc010aeg.2_Nonsense_Mutation_p.Q575*|TDRD3_uc001vib.3_Nonsense_Mutation_p.Q481*	NM_030794	NP_110421	Q9H7E2	TDRD3_HUMAN	tudor domain containing 3 isoform 2	482					chromatin modification	cytoplasm|nucleus	chromatin binding|methylated histone residue binding|nucleic acid binding|transcription coactivator activity			upper_aerodigestive_tract(1)|skin(1)	2		Prostate(109;0.173)|Breast(118;0.174)		GBM - Glioblastoma multiforme(99;0.000291)		TACTGATTATCAGAATCCAGT	0.323000												
SLITRK6	84189	broad.mit.edu	37	13	86369349	86369349	+	Missense_Mutation	SNP	A	A	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr13:86369349A>C	uc001vll.1	-	2	1754	c.1295T>G	c.(1294-1296)CTT>CGT	p.L432R	SLITRK6_uc010afe.1_Intron	NM_032229	NP_115605	Q9H5Y7	SLIK6_HUMAN	slit and trk like 6 precursor	432	Extracellular (Potential).|LRR 8.					integral to membrane				large_intestine(1)|ovary(1)|central_nervous_system(1)	3	all_neural(89;0.117)|Medulloblastoma(90;0.163)			GBM - Glioblastoma multiforme(99;0.0456)		ATGGAGACCAAGGAACATGCC	0.343000												
FAM155A	728215	broad.mit.edu	37	13	108518657	108518657	+	Silent	SNP	C	C	G			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr13:108518657C>G	uc001vql.2	-	1	804	c.288G>C	c.(286-288)CGG>CGC	p.R96R		NM_001080396	NP_001073865	B1AL88	F155A_HUMAN	family with sequence similarity 155, member A	96						integral to membrane	binding			skin(1)	1						cctgctgccgccgctgctgct	0.413000												
C14orf21	161424	broad.mit.edu	37	14	24771558	24771558	+	Silent	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr14:24771558G>A	uc001wol.1	+	5	1134	c.1071G>A	c.(1069-1071)CAG>CAA	p.Q357Q	C14orf21_uc001wom.1_5'Flank|DHRS1_uc001woj.1_5'Flank|DHRS1_uc001wok.2_5'Flank	NM_174913	NP_777573	Q86U38	CN021_HUMAN	hypothetical protein LOC161424	357	Pumilio 4.						RNA binding			breast(2)|central_nervous_system(1)|skin(1)	4				GBM - Glioblastoma multiforme(265;0.0185)		GGCAGCTGCAGACCCTGGCTG	0.522000												
C14orf106	55320	broad.mit.edu	37	14	45705143	45705143	+	Missense_Mutation	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr14:45705143C>T	uc001wwf.2	-	6	1681	c.1222G>A	c.(1222-1224)GTC>ATC	p.V408I	C14orf106_uc010anh.2_RNA	NM_018353	NP_060823	Q6P0N0	M18BP_HUMAN	chromosome 14 open reading frame 106	408					cell division|CenH3-containing nucleosome assembly at centromere|mitosis	chromosome, centromeric region|nucleoplasm	DNA binding				0						ATGTTAGTGACGTCTCTAGGA	0.299000												
NEO1	4756	broad.mit.edu	37	15	73528822	73528822	+	Missense_Mutation	SNP	T	T	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr15:73528822T>C	uc002avm.3	+	8	1568	c.1426T>C	c.(1426-1428)TTC>CTC	p.F476L	NEO1_uc010ukx.1_Missense_Mutation_p.F476L|NEO1_uc010uky.1_Missense_Mutation_p.F476L|NEO1_uc010ukz.1_5'UTR|NEO1_uc002avn.3_Missense_Mutation_p.F141L	NM_002499	NP_002490	Q92859	NEO1_HUMAN	neogenin homolog 1 precursor	476	Extracellular (Potential).|Fibronectin type-III 1.				axon guidance|cell adhesion|positive regulation of muscle cell differentiation	Golgi apparatus|integral to plasma membrane|nucleus				pancreas(1)	1						CTACTCTGTGTTCTACACCAA	0.557000												
DHX8	1659	broad.mit.edu	37	17	41584527	41584527	+	Missense_Mutation	SNP	A	A	G			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr17:41584527A>G	uc002idu.1	+	13	1958	c.1885A>G	c.(1885-1887)AGA>GGA	p.R629G	DHX8_uc010wif.1_Missense_Mutation_p.R538G|DHX8_uc010wig.1_Missense_Mutation_p.R629G	NM_004941	NP_004932	Q14562	DHX8_HUMAN	DEAH (Asp-Glu-Ala-His) box polypeptide 8	629	Helicase ATP-binding.					catalytic step 2 spliceosome	ATP binding|ATP-dependent RNA helicase activity|protein binding|RNA binding			ovary(2)|kidney(1)|pancreas(1)	4		Breast(137;0.00908)		BRCA - Breast invasive adenocarcinoma(366;0.08)		GGTGGCCAAAAGAGTGTCAGA	0.517000												
SCN4A	6329	broad.mit.edu	37	17	62025364	62025364	+	Silent	SNP	G	G	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr17:62025364G>T	uc002jds.1	-	17	3281	c.3204C>A	c.(3202-3204)GCC>GCA	p.A1068A		NM_000334	NP_000325	P35499	SCN4A_HUMAN	voltage-gated sodium channel type 4 alpha	1068	III.|Helical; Name=S2 of repeat III; (Potential).				muscle contraction	voltage-gated sodium channel complex	voltage-gated sodium channel activity			ovary(1)|pancreas(1)|skin(1)	3					Lamotrigine(DB00555)	AGACCTTGTCGGCATATTCTA	0.567000												
DLGAP1	9229	broad.mit.edu	37	18	3581872	3581872	+	Splice_Site	SNP	C	C	G			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr18:3581872C>G	uc002kmf.2	-	5	2032	c.1965_splice	c.e5+1	p.Q655_splice	DLGAP1_uc010wyz.1_Splice_Site_p.Q655_splice|DLGAP1_uc002kme.1_Splice_Site_p.Q353_splice|DLGAP1_uc010dkn.2_Splice_Site_p.Q363_splice|DLGAP1_uc010wyw.1_Splice_Site_p.Q361_splice|DLGAP1_uc010wyx.1_Splice_Site_p.Q377_splice|DLGAP1_uc010wyy.1_Splice_Site_p.Q339_splice|DLGAP1_uc002kmg.2_Splice_Site_p.Q353_splice	NM_004746	NP_004737	O14490	DLGP1_HUMAN	discs large homolog-associated protein 1 isoform						synaptic transmission	cell junction|postsynaptic density|postsynaptic membrane				ovary(2)|pancreas(1)|skin(1)	4		Colorectal(8;0.0257)				GAGGCTGTTACCTGTATCCCG	0.333000												
CCDC102B	79839	broad.mit.edu	37	18	66513583	66513583	+	Silent	SNP	A	A	G			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr18:66513583A>G	uc002lkk.2	+	6	1084	c.861A>G	c.(859-861)AGA>AGG	p.R287R	CCDC102B_uc002lki.2_Silent_p.R287R|CCDC102B_uc002lkj.1_Silent_p.R287R	NM_001093729	NP_001087198	Q68D86	C102B_HUMAN	coiled-coil domain containing 102B	287	Potential.									ovary(1)|lung(1)|skin(1)	3		Esophageal squamous(42;0.0559)|Colorectal(73;0.0604)				AAATAGAGAGACTGGAGTCGG	0.343000												
UHRF1	29128	broad.mit.edu	37	19	4930857	4930857	+	Missense_Mutation	SNP	G	G	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr19:4930857G>C	uc002mbo.2	+	4	706	c.538G>C	c.(538-540)GAG>CAG	p.E180Q	UHRF1_uc010xik.1_Intron|UHRF1_uc010duf.2_RNA|UHRF1_uc002mbp.2_Missense_Mutation_p.E193Q	NM_001048201	NP_001041666	Q96T88	UHRF1_HUMAN	ubiquitin-like with PHD and ring finger domains	180					cell cycle|cell proliferation|DNA repair|regulation of transcription from RNA polymerase II promoter	nucleus	acid-amino acid ligase activity|methyl-CpG binding|methylated histone residue binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			lung(2)	2				UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.0276)		GGCGCTGGAGGAGGACGTCAT	0.652000												
ZNF574	64763	broad.mit.edu	37	19	42584467	42584467	+	Missense_Mutation	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr19:42584467G>A	uc002osm.3	+	2	1878	c.1709G>A	c.(1708-1710)CGC>CAC	p.R570H	ZNF574_uc002osk.3_Missense_Mutation_p.R660H	NM_022752	NP_073589	Q6ZN55	ZN574_HUMAN	zinc finger protein 574	570	C2H2-type 12.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0		Prostate(69;0.059)				AGGCAGCACCGCTTGGTGCAT	0.627000												
PSG7	5676	broad.mit.edu	37	19	43430856	43430856	+	Missense_Mutation	SNP	T	T	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr19:43430856T>A	uc002ovl.3	-	5	824	c.722A>T	c.(721-723)AAG>ATG	p.K241M	PSG3_uc002ouf.2_Intron|PSG11_uc002ouw.2_Intron|PSG7_uc002ous.1_RNA|PSG7_uc002out.1_Intron|PSG10_uc002ouv.1_Intron|PSG6_uc002ovh.1_Intron|PSG6_uc002ovi.2_Intron|PSG6_uc010xwk.1_Intron|PSG11_uc002ovk.1_Intron|PSG7_uc010xwl.1_Missense_Mutation_p.K119M	NM_002783	NP_002774	Q13046	PSG7_HUMAN	pregnancy specific beta-1-glycoprotein 7	241	Ig-like C2-type 2.				female pregnancy	extracellular region					0		Prostate(69;0.00682)				GATGTAGGGCTTGGGCAGCTT	0.473000												
ZNF701	55762	broad.mit.edu	37	19	53086109	53086109	+	Missense_Mutation	SNP	G	G	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr19:53086109G>T	uc002pzs.1	+	4	924	c.797G>T	c.(796-798)GGT>GTT	p.G266V	ZNF701_uc010ydn.1_Missense_Mutation_p.G332V	NM_018260	NP_060730	Q9NV72	ZN701_HUMAN	zinc finger protein 701	266					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0				OV - Ovarian serous cystadenocarcinoma(262;0.0105)|GBM - Glioblastoma multiforme(134;0.0402)		TGTCACACTGGTGAGAATCCT	0.418000												
CNOT3	4849	broad.mit.edu	37	19	54647253	54647253	+	Splice_Site	SNP	G	G	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr19:54647253G>C	uc002qdj.1	+	4	479	c.168_splice	c.e4+1	p.Q56_splice	CNOT3_uc010yel.1_Splice_Site_p.Q56_splice|CNOT3_uc002qdi.2_Splice_Site|CNOT3_uc002qdk.1_Splice_Site_p.Q56_splice|CNOT3_uc010ere.1_5'Flank	NM_014516	NP_055331	O75175	CNOT3_HUMAN	CCR4-NOT transcription complex, subunit 3						nuclear-transcribed mRNA poly(A) tail shortening|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasmic mRNA processing body|cytosol|nucleus	protein binding			ovary(2)|haematopoietic_and_lymphoid_tissue(1)	3	all_cancers(19;0.0065)|all_epithelial(19;0.00348)|all_lung(19;0.0175)|Lung NSC(19;0.0325)|Ovarian(34;0.19)					GAAGCTACAAGTGAGGGGGCT	0.338000												
TRIM28	10155	broad.mit.edu	37	19	59060921	59060921	+	Missense_Mutation	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr19:59060921G>A	uc002qtg.1	+	13	2175	c.1886G>A	c.(1885-1887)CGT>CAT	p.R629H	TRIM28_uc010eut.1_Missense_Mutation_p.R547H|TRIM28_uc002qth.1_Missense_Mutation_p.R244H	NM_005762	NP_005753	Q13263	TIF1B_HUMAN	tripartite motif-containing 28 protein	629	PHD-type.				epithelial to mesenchymal transition|positive regulation of transcription, DNA-dependent	nucleoplasm	chromo shadow domain binding|ligase activity|transcription corepressor activity|zinc ion binding			ovary(1)|lung(1)|breast(1)	3		all_cancers(17;4.4e-22)|all_epithelial(17;2.15e-16)|Lung NSC(17;1.24e-06)|all_lung(17;5.41e-06)|Colorectal(82;3.46e-05)|Renal(17;0.00179)|all_neural(62;0.00607)|Ovarian(87;0.0443)|Breast(46;0.0928)|Medulloblastoma(540;0.184)		UCEC - Uterine corpus endometrioid carcinoma (67;0.0434)|all cancers(4;1.39e-13)|Epithelial(4;1.01e-10)|OV - Ovarian serous cystadenocarcinoma(4;2.34e-09)|GBM - Glioblastoma multiforme(193;0.0102)|Lung(386;0.179)		ACCATTTGCCGTGTCTGCCAG	0.612000												
ZNF638	27332	broad.mit.edu	37	2	71650235	71650235	+	Missense_Mutation	SNP	G	G	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr2:71650235G>C	uc002shx.2	+	22	3910	c.3591G>C	c.(3589-3591)GAG>GAC	p.E1197D	ZNF638_uc010yqw.1_Missense_Mutation_p.E776D|ZNF638_uc002shy.2_Missense_Mutation_p.E1197D|ZNF638_uc002shz.2_Missense_Mutation_p.E1197D|ZNF638_uc002sia.2_Missense_Mutation_p.E1197D|ZNF638_uc002sib.1_Intron|ZNF638_uc010fed.2_Intron|ZNF638_uc002sic.2_Missense_Mutation_p.E294D|ZNF638_uc002sid.2_Intron	NM_014497	NP_055312	Q14966	ZN638_HUMAN	zinc finger protein 638	1197	Glu-rich.				RNA splicing	cytoplasm|nuclear speck	double-stranded DNA binding|nucleotide binding|RNA binding|zinc ion binding			pancreas(2)|ovary(1)|skin(1)	4						ATGCCGAGGAGTGTGCTTTAA	0.408000												
ZNF514	84874	broad.mit.edu	37	2	95815684	95815684	+	Silent	SNP	A	A	G			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr2:95815684A>G	uc002sue.1	-	5	920	c.546T>C	c.(544-546)GAT>GAC	p.D182D	ZNF514_uc002sud.1_Silent_p.D255D	NM_032788	NP_116177	Q96K75	ZN514_HUMAN	zinc finger protein 514	182					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0						TGAATTCTGTATCACATTTAT	0.398000												
MBD5	55777	broad.mit.edu	37	2	149247083	149247083	+	Silent	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr2:149247083G>A	uc002twm.3	+	12	4171	c.3183G>A	c.(3181-3183)CCG>CCA	p.P1061P	MBD5_uc010zbs.1_Intron|MBD5_uc010fns.2_Silent_p.P1061P|MBD5_uc002two.2_Silent_p.P319P|MBD5_uc002twp.2_Silent_p.P111P	NM_018328	NP_060798	Q9P267	MBD5_HUMAN	methyl-CpG binding domain protein 5	1061						chromosome|nucleus	chromatin binding|DNA binding			skin(3)|ovary(2)	5				BRCA - Breast invasive adenocarcinoma(221;0.0569)		AGTTGCAACCGAGGATTGACC	0.483000												
PARD3B	117583	broad.mit.edu	37	2	206480274	206480274	+	Missense_Mutation	SNP	A	A	G			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr2:206480274A>G	uc002var.1	+	23	3562	c.3355A>G	c.(3355-3357)ATG>GTG	p.M1119V	PARD3B_uc002vao.1_Missense_Mutation_p.M1018V|PARD3B_uc002vap.1_Missense_Mutation_p.M1057V|PARD3B_uc002vaq.1_Missense_Mutation_p.M1050V|uc010fuc.1_5'Flank	NM_152526	NP_689739	Q8TEW8	PAR3L_HUMAN	par-3 partitioning defective 3 homolog B isoform	1119					cell cycle|cell division	endomembrane system|tight junction				skin(2)|ovary(1)|breast(1)	4		all_cancers(1;2.88e-06)|all_epithelial(1;3.23e-06)		Epithelial(149;0.0739)		GGCTCATCCTATGCACCCTCC	0.612000												
PRKAG3	53632	broad.mit.edu	37	2	219694947	219694947	+	Silent	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr2:219694947G>A	uc002vjb.1	-	4	406	c.387C>T	c.(385-387)AGC>AGT	p.S129S	PRKAG3_uc010zkn.1_RNA|PRKAG3_uc010fvy.1_Silent_p.S129S|PRKAG3_uc010zko.1_Silent_p.S125S	NM_017431	NP_059127	Q9UGI9	AAKG3_HUMAN	AMP-activated protein kinase, non-catalytic	129					cell cycle arrest|fatty acid biosynthetic process|insulin receptor signaling pathway|intracellular protein kinase cascade|regulation of fatty acid oxidation	cytosol	AMP-activated protein kinase activity|protein kinase binding			ovary(1)|lung(1)	2		Renal(207;0.0474)		Epithelial(149;4.35e-07)|all cancers(144;8.96e-05)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00942)		CATCATCTGTGCTGGAGCCTG	0.642000												
SIRPB1	10326	broad.mit.edu	37	20	1551635	1551635	+	Silent	SNP	G	G	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr20:1551635G>T	uc010gai.2	-	4	999	c.900C>A	c.(898-900)ACC>ACA	p.T300T	SIRPB1_uc002wfk.3_Intron	NM_006065	NP_006056	O00241	SIRB1_HUMAN	signal-regulatory protein beta 1 isoform 1	300	Ig-like C1-type 2.|Extracellular (Potential).				cell junction assembly|cell surface receptor linked signaling pathway	integral to plasma membrane	protein binding			ovary(1)	1						TCTCTATGAGGGTCGAAGCTG	0.562000												
RALGAPA2	57186	broad.mit.edu	37	20	20453517	20453517	+	Silent	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr20:20453517G>A	uc002wrz.2	-	37	5594	c.5451C>T	c.(5449-5451)AAC>AAT	p.N1817N	RALGAPA2_uc010gcx.2_Silent_p.N1521N|RALGAPA2_uc010zsg.1_Silent_p.N1265N|RALGAPA2_uc002wsa.1_Silent_p.N589N	NM_020343	NP_065076	Q2PPJ7	RGPA2_HUMAN	akt substrate AS250	1817	Rap-GAP.				activation of Ral GTPase activity	cytosol|nucleus	protein heterodimerization activity|Ral GTPase activator activity			ovary(1)	1						CCCTGCTGGCGTTGATGCACG	0.468000												
BCAS1	8537	broad.mit.edu	37	20	52583568	52583568	+	Silent	SNP	T	T	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr20:52583568T>A	uc002xws.2	-	9	1565	c.1227A>T	c.(1225-1227)GTA>GTT	p.V409V	BCAS1_uc010zza.1_Intron|BCAS1_uc010zzb.1_Silent_p.V357V|BCAS1_uc010gim.2_Intron|BCAS1_uc002xwt.2_Silent_p.V395V|BCAS1_uc010gil.1_Intron	NM_003657	NP_003648	O75363	BCAS1_HUMAN	breast carcinoma amplified sequence 1	409						cytoplasm	protein binding			ovary(2)|central_nervous_system(1)	3	Breast(2;9.53e-15)|Lung NSC(4;5.57e-06)|all_lung(4;1.44e-05)		STAD - Stomach adenocarcinoma(23;0.116)|Colorectal(105;0.198)			AGGCTGATTCTACTTCCTTGG	0.418000												
TFAP2C	7022	broad.mit.edu	37	20	55208570	55208570	+	Nonsense_Mutation	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr20:55208570C>T	uc002xya.2	+	4	991	c.748C>T	c.(748-750)CGA>TGA	p.R250*	TFAP2C_uc010zzi.1_Nonsense_Mutation_p.R81*	NM_003222	NP_003213	Q92754	AP2C_HUMAN	transcription factor AP-2 gamma	250					cell-cell signaling|male gonad development|regulation of transcription from RNA polymerase II promoter	nucleus	DNA binding|protein dimerization activity|sequence-specific DNA binding transcription factor activity			central_nervous_system(1)	1			Colorectal(105;0.229)			AGTACAGAGGCGACTGTCCCC	0.502000												
DSCAM	1826	broad.mit.edu	37	21	41414474	41414474	+	Missense_Mutation	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr21:41414474C>T	uc002yyq.1	-	32	5962	c.5510G>A	c.(5509-5511)TGC>TAC	p.C1837Y	DSCAM_uc002yyr.1_RNA	NM_001389	NP_001380	O60469	DSCAM_HUMAN	Down syndrome cell adhesion molecule isoform	1837	Cytoplasmic (Potential).				cell adhesion|dendrite self-avoidance|negative regulation of cell adhesion|positive regulation of axon extension involved in axon guidance|positive regulation of phosphorylation	axon|extracellular region|growth cone|integral to plasma membrane|membrane fraction	protein binding			ovary(6)|skin(4)|upper_aerodigestive_tract(1)	11		all_cancers(19;0.186)|Prostate(19;1.15e-05)|all_epithelial(19;0.0103)				TGATATGAAGCACTCCGTGAT	0.552000												
BCL2L13	23786	broad.mit.edu	37	22	18210043	18210043	+	Missense_Mutation	SNP	G	G	A	rs139164101	byFrequency	TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr22:18210043G>A	uc002zmw.2	+	7	1419	c.1201G>A	c.(1201-1203)GCA>ACA	p.A401T	BCL2L13_uc002zmx.2_Missense_Mutation_p.A239T|BCL2L13_uc002zmy.2_3'UTR|BCL2L13_uc010gqy.2_Missense_Mutation_p.A239T|BCL2L13_uc011agk.1_Missense_Mutation_p.A277T|BCL2L13_uc010gqz.2_Missense_Mutation_p.A121T|BCL2L13_uc002zmz.2_Missense_Mutation_p.A239T|BCL2L13_uc002zna.2_Missense_Mutation_p.A121T	NM_015367	NP_056182	Q9BXK5	B2L13_HUMAN	BCL2-like 13 (apoptosis facilitator)	401	Glu-rich.				induction of apoptosis	integral to membrane|mitochondrial membrane|nucleus	caspase activator activity			ovary(1)|lung(1)|central_nervous_system(1)|skin(1)	4		all_epithelial(15;0.123)		Lung(27;0.199)		GGTGGTCCCCGCACTGGAACC	0.522000												
CCDC71	64925	broad.mit.edu	37	3	49200840	49200840	+	Missense_Mutation	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr3:49200840G>A	uc003cwg.3	-	2	940	c.802C>T	c.(802-804)CGG>TGG	p.R268W		NM_022903	NP_075054	Q8IV32	CCD71_HUMAN	coiled-coil domain containing 71	268										ovary(1)	1				BRCA - Breast invasive adenocarcinoma(193;8.01e-05)|Kidney(197;0.00217)|KIRC - Kidney renal clear cell carcinoma(197;0.00244)		TTCATTCGCCGGACACTGGGG	0.647000												
FILIP1L	11259	broad.mit.edu	37	3	99568539	99568539	+	Nonsense_Mutation	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr3:99568539G>A	uc003dtm.2	-	5	2444	c.1981C>T	c.(1981-1983)CGA>TGA	p.R661*	C3orf26_uc003dtk.1_Intron|C3orf26_uc003dtl.2_Intron|FILIP1L_uc003dto.2_Nonsense_Mutation_p.R661*|FILIP1L_uc010hpf.2_Nonsense_Mutation_p.R237*|FILIP1L_uc010hpg.2_Nonsense_Mutation_p.R421*|FILIP1L_uc003dtn.2_Nonsense_Mutation_p.R421*|FILIP1L_uc003dtp.1_Nonsense_Mutation_p.R421*	NM_182909	NP_878913	Q4L180	FIL1L_HUMAN	filamin A interacting protein 1-like isoform 1	661	Potential.					cytoplasm|membrane|myosin complex|nucleus				ovary(1)	1						GCATACCTTCGTTCTAGAGTC	0.373000												
CEP97	79598	broad.mit.edu	37	3	101451439	101451439	+	Silent	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr3:101451439C>T	uc003dvk.1	+	6	696	c.669C>T	c.(667-669)ATC>ATT	p.I223I	CEP97_uc010hpm.1_Silent_p.I189I|CEP97_uc011bhf.1_Silent_p.I223I|CEP97_uc003dvl.1_5'UTR|CEP97_uc003dvm.1_Silent_p.I61I	NM_024548	NP_078824	Q8IW35	CEP97_HUMAN	centrosomal protein 97kDa	223	LRRCT.					centrosome|nucleus	protein binding			ovary(2)	2						GGCCGTACATCGTCAGCTGGT	0.418000												
UMPS	7372	broad.mit.edu	37	3	124462864	124462864	+	Missense_Mutation	SNP	G	G	A	rs142909683		TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr3:124462864G>A	uc003ehl.3	+	6	1482	c.1376G>A	c.(1375-1377)CGT>CAT	p.R459H	UMPS_uc003ehm.3_RNA|UMPS_uc011bka.1_Missense_Mutation_p.R281H|UMPS_uc011bkb.1_Missense_Mutation_p.R367H|UMPS_uc011bkc.1_Missense_Mutation_p.R281H|UMPS_uc003ehn.3_Missense_Mutation_p.R281H|UMPS_uc011bkd.1_Missense_Mutation_p.R184H	NM_000373	NP_000364	P11172	UMPS_HUMAN	uridine monophosphate synthase	459	OMPdecase.				'de novo' pyrimidine base biosynthetic process|'de novo' UMP biosynthetic process|pyrimidine nucleoside biosynthetic process	cytosol|nucleus	orotate phosphoribosyltransferase activity|orotidine-5'-phosphate decarboxylase activity			kidney(1)	1				GBM - Glioblastoma multiforme(114;0.146)		GCAGCTGATCGTCTGGAAGCA	0.428000												
IGSF10	285313	broad.mit.edu	37	3	151163813	151163813	+	Missense_Mutation	SNP	G	G	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr3:151163813G>C	uc011bod.1	-	4	3956	c.3956C>G	c.(3955-3957)CCA>CGA	p.P1319R		NM_178822	NP_849144	Q6WRI0	IGS10_HUMAN	immunoglobulin superfamily, member 10 precursor	1319					cell differentiation|multicellular organismal development|ossification	extracellular region				skin(7)|ovary(5)|central_nervous_system(1)	13			LUSC - Lung squamous cell carcinoma(72;0.0394)|Lung(72;0.0517)			AGTTGTTGCTGGTATTGCTGT	0.423000												
HRASLS	57110	broad.mit.edu	37	3	192988433	192988433	+	Missense_Mutation	SNP	C	C	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr3:192988433C>A	uc003fta.2	+	4	851	c.446C>A	c.(445-447)GCT>GAT	p.A149D		NM_020386	NP_065119	Q9HDD0	HRSL1_HUMAN	HRAS-like suppressor	149											0	all_cancers(143;9.1e-09)|Ovarian(172;0.0386)		OV - Ovarian serous cystadenocarcinoma(49;5.56e-18)|LUSC - Lung squamous cell carcinoma(58;6.08e-06)|Lung(62;6.49e-06)	GBM - Glioblastoma multiforme(46;0.000159)		GTGACAGCTGCTGTTGGTGTC	0.373000												
ARHGAP24	83478	broad.mit.edu	37	4	86916641	86916641	+	Missense_Mutation	SNP	G	G	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr4:86916641G>C	uc003hpk.2	+	9	2283	c.1834G>C	c.(1834-1836)GAC>CAC	p.D612H	ARHGAP24_uc003hpl.2_Missense_Mutation_p.D517H|ARHGAP24_uc010ikf.2_Missense_Mutation_p.D527H|ARHGAP24_uc003hpm.2_Missense_Mutation_p.D519H	NM_001025616	NP_001020787	Q8N264	RHG24_HUMAN	Rho GTPase activating protein 24 isoform 1	612					angiogenesis|cell differentiation|regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	cell projection|cytoskeleton|cytosol|focal adhesion	GTPase activator activity|protein binding				0		Hepatocellular(203;0.114)|all_hematologic(202;0.21)|Acute lymphoblastic leukemia(40;0.242)		OV - Ovarian serous cystadenocarcinoma(123;0.000571)		AAGCAAAAGTGACCACAGGAG	0.552000												
TTC29	83894	broad.mit.edu	37	4	147788681	147788681	+	Nonsense_Mutation	SNP	A	A	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr4:147788681A>C	uc003ikw.3	-	8	1081	c.854T>G	c.(853-855)TTA>TGA	p.L285*	TTC29_uc010ipc.2_RNA|TTC29_uc003ikx.3_Nonsense_Mutation_p.L311*|TTC29_uc010ipd.1_Nonsense_Mutation_p.L285*	NM_031956	NP_114162	Q8NA56	TTC29_HUMAN	tetratricopeptide repeat domain 29	285	TPR 3.						binding				0	all_hematologic(180;0.151)					CTCAGCAGCTAAGTGTGCTAA	0.294000												
GPR98	84059	broad.mit.edu	37	5	90004691	90004691	+	Missense_Mutation	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr5:90004691C>T	uc003kju.2	+	39	8885	c.8789C>T	c.(8788-8790)ACC>ATC	p.T2930I	GPR98_uc003kjt.2_Missense_Mutation_p.T636I|GPR98_uc003kjv.2_Missense_Mutation_p.T530I	NM_032119	NP_115495	Q8WXG9	GPR98_HUMAN	G protein-coupled receptor 98 precursor	2930	Extracellular (Potential).				cell communication|cell-cell adhesion|maintenance of organ identity|neuropeptide signaling pathway|photoreceptor cell maintenance	cell surface|cytoplasm|integral to membrane|plasma membrane	calcium ion binding|G-protein coupled receptor activity			ovary(11)|central_nervous_system(3)|pancreas(2)	16		all_cancers(142;1.05e-09)|all_epithelial(76;1.81e-12)|all_lung(232;5.41e-06)|Lung NSC(167;1.72e-05)|Ovarian(174;0.00948)|Colorectal(57;0.133)|Breast(839;0.192)		OV - Ovarian serous cystadenocarcinoma(54;7.01e-30)|Epithelial(54;6.79e-25)|all cancers(79;1.88e-20)		GTTGGACTTACCATGGCTGCT	0.348000												
EPB41L4A	64097	broad.mit.edu	37	5	111754701	111754701	+	Nonsense_Mutation	SNP	G	G	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr5:111754701G>T	uc003kpv.1	-	1	310	c.36C>A	c.(34-36)TAC>TAA	p.Y12*	EPB41L4A_uc003kpw.1_Nonsense_Mutation_p.Y12*|FLJ11235_uc003kpx.1_5'Flank	NM_022140	NP_071423	Q9HCS5	E41LA_HUMAN	erythrocyte protein band 4.1-like 4	12	FERM.					cytoplasm|cytoskeleton|extrinsic to membrane	cytoskeletal protein binding			ovary(1)	1		all_cancers(142;4.93e-06)|all_epithelial(76;2.28e-08)|Prostate(80;0.000244)|Colorectal(10;0.000788)|Ovarian(225;0.0448)|Lung NSC(167;0.126)|all_lung(232;0.135)		OV - Ovarian serous cystadenocarcinoma(64;6.24e-09)|Epithelial(69;1.43e-07)|all cancers(49;2.78e-05)|COAD - Colon adenocarcinoma(37;0.0467)|Colorectal(14;0.0791)		AAACTTCGCAGTAAAATTCTT	0.612000												
KIF20A	10112	broad.mit.edu	37	5	137521329	137521329	+	Silent	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr5:137521329C>T	uc003lcj.2	+	16	2551	c.2055C>T	c.(2053-2055)TCC>TCT	p.S685S	KIF20A_uc011cyo.1_Silent_p.S667S	NM_005733	NP_005724	O95235	KI20A_HUMAN	kinesin family member 20A	685	Potential.				cytokinesis|M phase of mitotic cell cycle|microtubule-based movement|protein transport|vesicle-mediated transport	Golgi apparatus|microtubule|nucleoplasm	ATP binding|microtubule motor activity|protein binding|transporter activity				0			KIRC - Kidney renal clear cell carcinoma(527;0.0101)|Kidney(363;0.0109)			CTTCTGCCTCCACCCAGCAGC	0.507000												
PCDHGA10	56106	broad.mit.edu	37	5	140793840	140793840	+	Silent	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr5:140793840G>A	uc003lkl.1	+	1	1098	c.1098G>A	c.(1096-1098)CTG>CTA	p.L366L	PCDHGA1_uc003lji.1_Intron|PCDHGA2_uc003ljk.1_Intron|PCDHGA3_uc003ljm.1_Intron|PCDHGA3_uc010jfx.1_Intron|PCDHGB1_uc003ljo.1_Intron|PCDHGA4_uc003ljq.1_Intron|PCDHGB2_uc003ljs.1_Intron|PCDHGA5_uc003lju.1_Intron|PCDHGB3_uc003ljw.1_Intron|PCDHGA6_uc003ljy.1_Intron|PCDHGA7_uc003lka.1_Intron|PCDHGB4_uc003lkc.1_Intron|PCDHGA8_uc003lkd.1_Intron|PCDHGB5_uc003lkf.1_Intron|PCDHGA9_uc003lkh.1_Intron|PCDHGB6_uc003lkj.1_Intron|PCDHGA10_uc011day.1_Silent_p.L366L	NM_018913	NP_061736	Q9Y5H3	PCDGA_HUMAN	protocadherin gamma subfamily A, 10 isoform 1	366	Cadherin 4.|Extracellular (Potential).				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding				0			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			ATTCACCTCTGGGAACAGTCG	0.403000												
FBXW11	23291	broad.mit.edu	37	5	171295748	171295748	+	Missense_Mutation	SNP	C	C	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr5:171295748C>A	uc003mbm.1	-	12	1891	c.1520G>T	c.(1519-1521)AGC>ATC	p.S507I	FBXW11_uc011dey.1_Missense_Mutation_p.S475I|FBXW11_uc003mbl.1_Missense_Mutation_p.S494I|FBXW11_uc003mbn.1_Missense_Mutation_p.S473I	NM_012300	NP_036432	Q9UKB1	FBW1B_HUMAN	F-box and WD repeat domain containing 11 isoform	507	WD 7.				cell cycle|negative regulation of transcription, DNA-dependent|positive regulation of circadian rhythm|positive regulation of proteolysis|positive regulation of transcription, DNA-dependent|protein dephosphorylation|protein destabilization|protein polyubiquitination|rhythmic process|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|Wnt receptor signaling pathway	centrosome|cytosol|nucleus|SCF ubiquitin ligase complex	protein binding|ubiquitin-protein ligase activity			ovary(1)|breast(1)	2	Renal(175;0.000159)|Lung NSC(126;0.00384)|all_lung(126;0.00659)	Medulloblastoma(196;0.00853)|all_neural(177;0.026)	Kidney(164;7.24e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000516)			ATGGGAGCTGCTGATGATCTG	0.423000												
BAI3	577	broad.mit.edu	37	6	70042817	70042817	+	Silent	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr6:70042817C>T	uc003pev.3	+	24	3553	c.3105C>T	c.(3103-3105)GTC>GTT	p.V1035V	BAI3_uc010kak.2_Silent_p.V1035V|BAI3_uc011dxx.1_Silent_p.V241V|BAI3_uc003pex.1_Silent_p.V165V	NM_001704	NP_001695	O60242	BAI3_HUMAN	brain-specific angiogenesis inhibitor 3	1035	Helical; Name=5; (Potential).				negative regulation of angiogenesis|neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			lung(27)|ovary(8)|skin(6)|pancreas(4)|central_nervous_system(3)|urinary_tract(1)|breast(1)	50		all_lung(197;0.212)				TTTGACAGGTCAACATGGTGA	0.383000												
KCNQ5	56479	broad.mit.edu	37	6	73904416	73904416	+	Missense_Mutation	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr6:73904416C>T	uc003pgk.2	+	14	2425	c.2078C>T	c.(2077-2079)ACG>ATG	p.T693M	KCNQ5_uc011dyh.1_Missense_Mutation_p.T712M|KCNQ5_uc011dyi.1_Missense_Mutation_p.T703M|KCNQ5_uc010kat.2_Missense_Mutation_p.T684M|KCNQ5_uc011dyj.1_Missense_Mutation_p.T583M|KCNQ5_uc011dyk.1_Missense_Mutation_p.T443M	NM_019842	NP_062816	Q9NR82	KCNQ5_HUMAN	potassium voltage-gated channel, KQT-like	693					protein complex assembly|synaptic transmission	voltage-gated potassium channel complex	inward rectifier potassium channel activity			ovary(4)|large_intestine(2)|skin(1)	7		all_epithelial(107;0.116)|Lung NSC(302;0.219)		COAD - Colon adenocarcinoma(1;0.0107)|Colorectal(1;0.0583)		TTCATTCTGACGCCAAATGAG	0.502000												
PAPOLB	56903	broad.mit.edu	37	7	4901375	4901375	+	Missense_Mutation	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr7:4901375C>T	uc003snk.2	-	1	251	c.67G>A	c.(67-69)GTC>ATC	p.V23I	RADIL_uc003sng.1_Intron|RADIL_uc011jwd.1_Intron|RADIL_uc003snj.1_Intron	NM_020144	NP_064529	Q9NRJ5	PAPOB_HUMAN	poly(A) polymerase beta (testis specific)	22					mRNA processing|RNA polyadenylation|transcription, DNA-dependent	nucleus	ATP binding|metal ion binding|polynucleotide adenylyltransferase activity|RNA binding			ovary(1)	1		Ovarian(82;0.0175)		UCEC - Uterine corpus endometrioid carcinoma (126;0.089)|OV - Ovarian serous cystadenocarcinoma(56;2.06e-14)		GGCGAGGAGACGCCGTAGCGA	0.662000												
PHF14	9678	broad.mit.edu	37	7	11091378	11091378	+	Missense_Mutation	SNP	G	G	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr7:11091378G>C	uc003sry.1	+	14	2887	c.2452G>C	c.(2452-2454)GAA>CAA	p.E818Q	PHF14_uc011jxi.1_Missense_Mutation_p.E533Q|PHF14_uc003srz.2_Missense_Mutation_p.E818Q|PHF14_uc011jxj.1_Missense_Mutation_p.E533Q	NM_014660	NP_055475	O94880	PHF14_HUMAN	PHD finger protein 14 isoform 2	818							zinc ion binding			kidney(2)|skin(1)	3				UCEC - Uterine corpus endometrioid carcinoma (126;0.205)		TGTGCCACCAGAACCCAAGAA	0.403000												
CDK13	8621	broad.mit.edu	37	7	40132775	40132775	+	Silent	SNP	A	A	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr7:40132775A>C	uc003thh.3	+	13	3909	c.3627A>C	c.(3625-3627)GGA>GGC	p.G1209G	CDK13_uc003thi.3_Silent_p.G1149G|CDK13_uc003thj.2_Silent_p.G260G|CDK13_uc003thk.2_Silent_p.G142G	NM_003718	NP_003709	Q14004	CDK13_HUMAN	cell division cycle 2-like 5 isoform 1	1209					alternative nuclear mRNA splicing, via spliceosome|hemopoiesis|interspecies interaction between organisms|phosphorylation of RNA polymerase II C-terminal domain|positive regulation of cell proliferation|regulation of mitosis	nuclear cyclin-dependent protein kinase holoenzyme complex|nuclear speck	ATP binding|cyclin-dependent protein kinase activity|protein binding|RNA polymerase II carboxy-terminal domain kinase activity			lung(2)|skin(2)|ovary(1)	5						GGGAAAATGGATCGGGACATG	0.493000												
TAF6	6878	broad.mit.edu	37	7	99709580	99709580	+	Missense_Mutation	SNP	T	T	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr7:99709580T>C	uc003uti.2	-	8	844	c.763A>G	c.(763-765)ATG>GTG	p.M255V	TAF6_uc003utg.2_Missense_Mutation_p.M177V|TAF6_uc003uth.2_Missense_Mutation_p.M312V|TAF6_uc003utk.2_Missense_Mutation_p.M255V|TAF6_uc011kji.1_Missense_Mutation_p.M292V|TAF6_uc003utj.2_Missense_Mutation_p.M245V|TAF6_uc003utl.2_Missense_Mutation_p.M255V|TAF6_uc003utm.2_Missense_Mutation_p.M255V|TAF6_uc003utn.1_RNA	NM_139315	NP_647476	P49848	TAF6_HUMAN	TBP-associated factor 6 isoform alpha	255					negative regulation of cell cycle|negative regulation of cell proliferation|regulation of sequence-specific DNA binding transcription factor activity|transcription elongation from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|viral reproduction	cytoplasm|MLL1 complex|transcription factor TFIID complex|transcription factor TFIID complex|transcription factor TFTC complex	DNA binding|protein binding|sequence-specific DNA binding transcription factor activity			ovary(1)|central_nervous_system(1)	2	Lung NSC(181;0.0181)|all_lung(186;0.0284)|Esophageal squamous(72;0.0439)					CGTGGCAGCATCTGATACAGT	0.602000												
KCNU1	157855	broad.mit.edu	37	8	36644891	36644891	+	Missense_Mutation	SNP	G	G	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr8:36644891G>C	uc010lvw.2	+	2	350	c.263G>C	c.(262-264)CGT>CCT	p.R88P	KCNU1_uc003xjw.2_RNA	NM_001031836	NP_001027006	A8MYU2	KCNU1_HUMAN	potassium channel, subfamily U, member 1	88	Cytoplasmic (Potential).					voltage-gated potassium channel complex	binding|large conductance calcium-activated potassium channel activity|voltage-gated potassium channel activity			ovary(1)	1				KIRC - Kidney renal clear cell carcinoma(67;0.0504)|Kidney(114;0.0634)		GGACAATTTCGTGATCATATA	0.423000												
XKR4	114786	broad.mit.edu	37	8	56015173	56015173	+	Missense_Mutation	SNP	C	C	T			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr8:56015173C>T	uc003xsf.2	+	1	157	c.125C>T	c.(124-126)TCG>TTG	p.S42L		NM_052898	NP_443130	Q5GH76	XKR4_HUMAN	XK, Kell blood group complex subunit-related	42						integral to membrane				pancreas(2)	2			Epithelial(17;0.000117)|all cancers(17;0.000836)			CCGTCGGGGTCGGGAGCCGAG	0.368000												
OXR1	55074	broad.mit.edu	37	8	107691447	107691447	+	Missense_Mutation	SNP	A	A	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr8:107691447A>C	uc011lht.1	+	3	332	c.233A>C	c.(232-234)CAA>CCA	p.Q78P	OXR1_uc003ymf.2_Missense_Mutation_p.Q77P|OXR1_uc011lhu.1_Missense_Mutation_p.Q70P|OXR1_uc010mcg.2_Intron|OXR1_uc003ymg.1_Missense_Mutation_p.Q10P|OXR1_uc003ymi.1_5'UTR	NM_018002	NP_060472	Q8N573	OXR1_HUMAN	oxidation resistance 1 isoform 1	78					cell wall macromolecule catabolic process|response to oxidative stress	mitochondrion					0			OV - Ovarian serous cystadenocarcinoma(57;1.81e-09)			GACACTGGCCAAAAGAAGACC	0.368000												
FLJ43860	389690	broad.mit.edu	37	8	142487931	142487931	+	Missense_Mutation	SNP	T	T	G			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr8:142487931T>G	uc003ywi.2	-	11	1391	c.1310A>C	c.(1309-1311)GAG>GCG	p.E437A	FLJ43860_uc011ljs.1_RNA|FLJ43860_uc010meu.1_RNA	NM_207414	NP_997297	Q6ZUA9	Q6ZUA9_HUMAN	hypothetical protein LOC389690	437							binding				0	all_cancers(97;7.79e-15)|all_epithelial(106;4.52e-13)|Lung NSC(106;2.07e-05)|all_lung(105;2.89e-05)|Ovarian(258;0.0303)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.0493)			GTGGGCGCCCTCACTCCGGCT	0.642000												
PLEC	5339	broad.mit.edu	37	8	145009469	145009469	+	Silent	SNP	G	G	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr8:145009469G>A	uc003zaf.1	-	7	1196	c.1026C>T	c.(1024-1026)ATC>ATT	p.I342I	PLEC_uc003zab.1_Silent_p.I205I|PLEC_uc003zac.1_Silent_p.I209I|PLEC_uc003zad.2_Silent_p.I205I|PLEC_uc003zae.1_Silent_p.I173I|PLEC_uc003zag.1_Silent_p.I183I|PLEC_uc003zah.2_Silent_p.I191I|PLEC_uc003zaj.2_Silent_p.I232I	NM_201380	NP_958782	Q15149	PLEC_HUMAN	plectin isoform 1	342	CH 2.|Globular 1.|Actin-binding.				cellular component disassembly involved in apoptosis|hemidesmosome assembly	cytosol|focal adhesion|hemidesmosome|intermediate filament cytoskeleton|sarcolemma	actin binding|structural constituent of muscle|structural constituent of muscle			large_intestine(2)|ovary(2)|pancreas(2)|upper_aerodigestive_tract(1)|central_nervous_system(1)|skin(1)	9						TGTTCATGTCGATGAGCAGGG	0.657000												
OPLAH	26873	broad.mit.edu	37	8	145109753	145109753	+	Missense_Mutation	SNP	C	C	T	rs11777194		TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr8:145109753C>T	uc003zar.3	-	18	2555	c.2473G>A	c.(2473-2475)GGG>AGG	p.G825R	OPLAH_uc003zas.1_Missense_Mutation_p.G74R	NM_017570	NP_060040	O14841	OPLA_HUMAN	5-oxoprolinase (ATP-hydrolysing)	825							5-oxoprolinase (ATP-hydrolyzing) activity|ATP binding				0	all_cancers(97;1.06e-10)|all_epithelial(106;1.5e-09)|Lung NSC(106;5.89e-05)|all_lung(105;0.000174)|Ovarian(258;0.0173)|Acute lymphoblastic leukemia(118;0.155)		OV - Ovarian serous cystadenocarcinoma(54;6.79e-41)|Epithelial(56;1.02e-39)|all cancers(56;2.24e-35)|Colorectal(110;0.055)|BRCA - Breast invasive adenocarcinoma(115;0.105)		L-Glutamic Acid(DB00142)	TGGCTGCCCCCGGCACTGGGA	0.642000												
NLGN4X	57502	broad.mit.edu	37	X	6069107	6069107	+	Missense_Mutation	SNP	G	G	C			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chrX:6069107G>C	uc010ndh.2	-	2	902	c.401C>G	c.(400-402)ACT>AGT	p.T134S	NLGN4X_uc004crp.2_Missense_Mutation_p.T134S|NLGN4X_uc004crq.2_Missense_Mutation_p.T134S|NLGN4X_uc010ndi.2_Missense_Mutation_p.T134S|NLGN4X_uc004crr.2_Missense_Mutation_p.T134S|NLGN4X_uc010ndj.2_Missense_Mutation_p.T134S	NM_181332	NP_851849	Q8N0W4	NLGNX_HUMAN	X-linked neuroligin 4 precursor	134	Extracellular (Potential).				brainstem development|cell adhesion|cell-cell junction organization|cerebellum development|male courtship behavior|positive regulation of organ growth|regulation of excitatory postsynaptic membrane potential|social behavior|synapse assembly|territorial aggressive behavior|vocalization behavior	cell surface|dendrite|integral to plasma membrane|synapse	chloride ion binding|neurexin binding|protein homodimerization activity|receptor activity			skin(2)|large_intestine(1)|ovary(1)	4						GGTCATCAAAGTATCCAAATT	0.453000												
KLHL13	90293	broad.mit.edu	37	X	117032969	117032969	+	Nonsense_Mutation	SNP	C	C	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chrX:117032969C>A	uc004eql.2	-	7	1932	c.1870G>T	c.(1870-1872)GAA>TAA	p.E624*	KLHL13_uc004eqk.2_Nonsense_Mutation_p.E573*|KLHL13_uc011mtn.1_Nonsense_Mutation_p.E464*|KLHL13_uc011mto.1_Nonsense_Mutation_p.E618*|KLHL13_uc011mtp.1_Nonsense_Mutation_p.E626*|KLHL13_uc004eqm.2_Nonsense_Mutation_p.E573*|KLHL13_uc011mtq.1_Nonsense_Mutation_p.E608*	NM_033495	NP_277030	Q9P2N7	KLH13_HUMAN	kelch-like 13	624	Kelch 6.				cytokinesis|mitosis|protein ubiquitination	Cul3-RING ubiquitin ligase complex				kidney(1)|skin(1)	2						CCAAGGGATTCTGGCAGATCA	0.438000												
DOCK11	139818	broad.mit.edu	37	X	117796673	117796673	+	Missense_Mutation	SNP	C	C	T	rs146074785		TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chrX:117796673C>T	uc004eqp.2	+	45	5057	c.4994C>T	c.(4993-4995)GCG>GTG	p.A1665V	DOCK11_uc004eqq.2_Missense_Mutation_p.A1444V	NM_144658	NP_653259	Q5JSL3	DOC11_HUMAN	dedicator of cytokinesis 11	1665	DHR-2.				blood coagulation	cytosol	GTP binding			ovary(3)	3						GGATGTTCAGCGTTCAAGAAA	0.368000												
ARID1A	8289	broad.mit.edu	37	1	27100120	27100123	+	Frame_Shift_Del	DEL	CAGC	CAGC	-			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr1:27100120_27100123delCAGC	uc001bmv.1	+	16	4289_4292	c.3916_3919delCAGC	c.(3916-3921)CAGCCGfs	p.Q1306fs	ARID1A_uc001bmt.1_Frame_Shift_Del_p.Q1305fs|ARID1A_uc001bmu.1_Frame_Shift_Del_p.Q1306fs|ARID1A_uc001bmw.1_Frame_Shift_Del_p.Q923fs|ARID1A_uc001bmx.1_Frame_Shift_Del_p.Q152fs|ARID1A_uc009vsm.1_5'UTR|ARID1A_uc009vsn.1_5'Flank	NM_006015	NP_006006	O14497	ARI1A_HUMAN	AT rich interactive domain 1A isoform a	1306_1307				P -> S (in Ref. 1; AAG33967, 5; AAG17549 and 7; BAA23269).	androgen receptor signaling pathway|chromatin-mediated maintenance of transcription|estrogen receptor signaling pathway|glucocorticoid receptor signaling pathway|nervous system development|nucleosome mobilization|transcription, DNA-dependent	nBAF complex|npBAF complex|SWI/SNF complex	DNA binding|protein binding			ovary(124)|pancreas(5)|central_nervous_system(3)|endometrium(3)|kidney(3)|skin(2)|upper_aerodigestive_tract(1)|lung(1)	142		all_cancers(24;6.36e-27)|all_epithelial(13;5.93e-24)|Colorectal(325;3.46e-05)|all_lung(284;4.76e-05)|Lung NSC(340;5.83e-05)|Breast(348;9.7e-05)|Renal(390;0.0007)|Ovarian(437;0.00473)|Myeloproliferative disorder(586;0.0255)|all_neural(195;0.0381)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0178)|all cancers(4;2.61e-56)|Epithelial(14;7.53e-55)|OV - Ovarian serous cystadenocarcinoma(117;4.5e-30)|Colorectal(126;2.07e-09)|COAD - Colon adenocarcinoma(152;4.29e-07)|BRCA - Breast invasive adenocarcinoma(304;4.13e-05)|STAD - Stomach adenocarcinoma(196;0.000279)|KIRC - Kidney renal clear cell carcinoma(1967;0.000794)|GBM - Glioblastoma multiforme(114;0.0132)|READ - Rectum adenocarcinoma(331;0.0469)|Lung(427;0.167)|LUSC - Lung squamous cell carcinoma(448;0.242)		TGGGGCCCCACAGCCGAATCTCAT	0.500			Mis|N|F|S|D		clear cell ovarian carcinoma|RCC							
HBD	3045	broad.mit.edu	37	11	5254296	5254297	+	Frame_Shift_Ins	INS	-	-	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr11:5254296_5254297insA	uc001maf.1	-	3	536_537	c.341_342insT	c.(340-342)GTGfs	p.V114fs		NM_000519	NP_000510	P02042	HBD_HUMAN	delta globin	114					blood coagulation	hemoglobin complex	heme binding|oxygen binding|oxygen transporter activity			ovary(1)	1		Medulloblastoma(188;0.00225)|Breast(177;0.0155)|all_neural(188;0.0212)		Epithelial(150;5.69e-10)|BRCA - Breast invasive adenocarcinoma(625;0.135)		TGCGGGCCAGCACACACACCAG	0.515												
HIST1H1B	3009	broad.mit.edu	37	6	27834714	27834716	+	In_Frame_Del	DEL	CGG	CGG	-			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr6:27834713_27834715TCGG>T	uc003njx.3	-	0	645_647	c.593_595CCGA>A	c.(592-597)ccgaag>cAag	p.198_199PK>Q		NM_005322	NP_005313	P16401	H15_HUMAN	Homo sapiens histone cluster 1, H1b (HIST1H1B), mRNA.	198					nucleosome assembly	nucleosome|nucleus	DNA binding	p.P198P(2)		endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(5)|lung(12)|prostate(2)|upper_aerodigestive_tract(2)	24						TTTGCCGCCTTCGGCTTAACTGC	0.562												
HBD	3045	broad.mit.edu	37	11	5254297	5254298	+	Frame_Shift_Ins	INS	-	-	A			TCGA-BR-A4J1-01A-11D-A25D-08	TCGA-BR-A4J1-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d994319-688e-483d-8df3-0dcbfbaf836a	5bfcbe72-fd16-4bd2-9ae0-90dd16426ffb	g.chr11:5254296_5254297C>CA	uc001maf.1	-	2	536_537	c.341_342G>TG	c.(340-342)gtgfs	p.V114fs		NM_000519	NP_000510	P02042	HBD_HUMAN	Homo sapiens hemoglobin, delta (HBD), mRNA.	114					blood coagulation	hemoglobin complex	heme binding|oxygen binding|oxygen transporter activity			endometrium(2)|large_intestine(3)|lung(9)|ovary(1)|prostate(1)	16		Medulloblastoma(188;0.00225)|Breast(177;0.0155)|all_neural(188;0.0212)		Epithelial(150;5.69e-10)|BRCA - Breast invasive adenocarcinoma(625;0.135)		TGCGGGCCAGCACACACACCAG	0.515