Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values
FAM58B	339521	broad.mit.edu	37	1	200182943	200182943	+	Silent	SNP	C	C	T			TCGA-BR-A4IZ-01A-32D-A25D-08	TCGA-BR-A4IZ-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ef5290da-bfcb-4880-9148-c8d5d1a6a4ac	f814337f-39ee-4808-b2fa-29b10610254f	g.chr1:200182943C>T	uc009wzi.1	+	1	288	c.252C>T	c.(250-252)GCC>GCT	p.A84A		NM_001105517	NP_001098987	P0C7Q3	FA58B_HUMAN	family with sequence similarity 58 member B	84					regulation of cyclin-dependent protein kinase activity|regulation of transcription, DNA-dependent		protein kinase binding				0	Prostate(682;0.19)					TTTACTTGGCCGGCAAAGTGG	0.542000												
CTSF	8722	broad.mit.edu	37	11	66335480	66335480	+	Missense_Mutation	SNP	C	C	T			TCGA-BR-A4IZ-01A-32D-A25D-08	TCGA-BR-A4IZ-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ef5290da-bfcb-4880-9148-c8d5d1a6a4ac	f814337f-39ee-4808-b2fa-29b10610254f	g.chr11:66335480C>T	uc001oip.2	-	2	377	c.287G>A	c.(286-288)CGG>CAG	p.R96Q		NM_003793	NP_003784	Q9UBX1	CATF_HUMAN	cathepsin F precursor	96					proteolysis	lysosome	cysteine-type endopeptidase activity				0						CACGGGGAGCCGGCACACCAT	0.652000												
CACNA1C	775	broad.mit.edu	37	12	2566863	2566863	+	Missense_Mutation	SNP	G	G	A			TCGA-BR-A4IZ-01A-32D-A25D-08	TCGA-BR-A4IZ-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ef5290da-bfcb-4880-9148-c8d5d1a6a4ac	f814337f-39ee-4808-b2fa-29b10610254f	g.chr12:2566863G>A	uc009zdu.1	+	5	1061	c.748G>A	c.(748-750)GGA>AGA	p.G250R	CACNA1C_uc009zdv.1_Missense_Mutation_p.G250R|CACNA1C_uc001qkb.2_Missense_Mutation_p.G250R|CACNA1C_uc001qkc.2_Missense_Mutation_p.G250R|CACNA1C_uc001qke.2_Missense_Mutation_p.G250R|CACNA1C_uc001qkf.2_Missense_Mutation_p.G250R|CACNA1C_uc001qjz.2_Missense_Mutation_p.G250R|CACNA1C_uc001qkd.2_Missense_Mutation_p.G250R|CACNA1C_uc001qkg.2_Missense_Mutation_p.G250R|CACNA1C_uc009zdw.1_Missense_Mutation_p.G250R|CACNA1C_uc001qkh.2_Missense_Mutation_p.G250R|CACNA1C_uc001qkl.2_Missense_Mutation_p.G250R|CACNA1C_uc001qkn.2_Missense_Mutation_p.G250R|CACNA1C_uc001qko.2_Missense_Mutation_p.G250R|CACNA1C_uc001qkp.2_Missense_Mutation_p.G250R|CACNA1C_uc001qkr.2_Missense_Mutation_p.G250R|CACNA1C_uc001qku.2_Missense_Mutation_p.G250R|CACNA1C_uc001qkq.2_Missense_Mutation_p.G250R|CACNA1C_uc001qks.2_Missense_Mutation_p.G250R|CACNA1C_uc001qkt.2_Missense_Mutation_p.G250R|CACNA1C_uc001qka.1_5'UTR|CACNA1C_uc001qki.1_5'UTR|CACNA1C_uc001qkj.1_5'UTR|CACNA1C_uc001qkk.1_5'UTR|CACNA1C_uc001qkm.1_5'UTR	NM_199460	NP_955630	Q13936	CAC1C_HUMAN	calcium channel, voltage-dependent, L type,	250	I.|Helical; Name=S4 of repeat I; (Potential).				axon guidance|calcium ion transport into cytosol|energy reserve metabolic process|regulation of insulin secretion	cytoplasm|postsynaptic density|voltage-gated calcium channel complex	calmodulin binding|voltage-gated calcium channel activity			ovary(10)|central_nervous_system(1)	11			OV - Ovarian serous cystadenocarcinoma(31;0.00256)	LUAD - Lung adenocarcinoma(1;0.134)	Ibutilide(DB00308)|Isradipine(DB00270)|Magnesium Sulfate(DB00653)|Mibefradil(DB01388)|Nicardipine(DB00622)|Verapamil(DB00661)	GCTGGTGTCCGGAGTCCCAAG	0.577000												
PPP4C	5531	broad.mit.edu	37	16	30094833	30094833	+	Missense_Mutation	SNP	G	G	A			TCGA-BR-A4IZ-01A-32D-A25D-08	TCGA-BR-A4IZ-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ef5290da-bfcb-4880-9148-c8d5d1a6a4ac	f814337f-39ee-4808-b2fa-29b10610254f	g.chr16:30094833G>A	uc002dwe.2	+	6	566	c.422G>A	c.(421-423)CGC>CAC	p.R141H	uc002dtf.2_Intron|BOLA2_uc010bzb.1_Intron|PPP4C_uc002dwf.2_Missense_Mutation_p.R141H|PPP4C_uc002dwg.2_RNA|PPP4C_uc002dwh.2_Missense_Mutation_p.R62H	NM_002720	NP_002711	P60510	PP4C_HUMAN	protein phosphatase 4, catalytic subunit	141					microtubule cytoskeleton organization|regulation of double-strand break repair via homologous recombination	centrosome|nucleus	metal ion binding|NF-kappaB-inducing kinase activity|protein binding|protein serine/threonine phosphatase activity			skin(1)	1						ACTGTGTGGCGCTACTGCACT	0.587000												
RFX1	5989	broad.mit.edu	37	19	14079448	14079448	+	Missense_Mutation	SNP	G	G	A			TCGA-BR-A4IZ-01A-32D-A25D-08	TCGA-BR-A4IZ-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ef5290da-bfcb-4880-9148-c8d5d1a6a4ac	f814337f-39ee-4808-b2fa-29b10610254f	g.chr19:14079448G>A	uc002mxv.2	-	12	1933	c.1661C>T	c.(1660-1662)GCG>GTG	p.A554V		NM_002918	NP_002909	P22670	RFX1_HUMAN	regulatory factor X1	554					immune response	nucleus	DNA binding|protein binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity			lung(1)|pancreas(1)	2			OV - Ovarian serous cystadenocarcinoma(19;6.67e-23)			CTGCCCCACCGCCACGCCGTT	0.662000												
PPP2R3A	5523	broad.mit.edu	37	3	135722102	135722102	+	Nonsense_Mutation	SNP	C	C	T			TCGA-BR-A4IZ-01A-32D-A25D-08	TCGA-BR-A4IZ-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ef5290da-bfcb-4880-9148-c8d5d1a6a4ac	f814337f-39ee-4808-b2fa-29b10610254f	g.chr3:135722102C>T	uc003eqv.1	+	2	2327	c.1762C>T	c.(1762-1764)CGA>TGA	p.R588*	PPP2R3A_uc011blz.1_Intron	NM_002718	NP_002709	Q06190	P2R3A_HUMAN	protein phosphatase 2, regulatory subunit B'',	588					protein dephosphorylation	protein phosphatase type 2A complex	calcium ion binding|protein binding|protein phosphatase type 2A regulator activity			ovary(3)|pancreas(1)|lung(1)|breast(1)|skin(1)	7						GGAAGAGGATCGAGCCCTCTT	0.408000												
SRP72	6731	broad.mit.edu	37	4	57356812	57356812	+	Splice_Site	SNP	G	G	A			TCGA-BR-A4IZ-01A-32D-A25D-08	TCGA-BR-A4IZ-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ef5290da-bfcb-4880-9148-c8d5d1a6a4ac	f814337f-39ee-4808-b2fa-29b10610254f	g.chr4:57356812G>A	uc003hbv.2	+	15	1542	c.1502_splice	c.e15+1	p.A501_splice	SRP72_uc010ihe.2_Splice_Site_p.A440_splice|SRP72_uc003hbw.1_Splice_Site_p.A262_splice	NM_006947	NP_008878	O76094	SRP72_HUMAN	signal recognition particle 72kDa						response to drug|SRP-dependent cotranslational protein targeting to membrane	cytosol|nucleolus|plasma membrane|signal recognition particle, endoplasmic reticulum targeting	7S RNA binding|signal recognition particle binding			ovary(1)	1	Glioma(25;0.08)|all_neural(26;0.101)					AAGCCAAAGCGTATCCTTTTG	0.299000												
TIGD4	201798	broad.mit.edu	37	4	153691406	153691406	+	Missense_Mutation	SNP	A	A	C			TCGA-BR-A4IZ-01A-32D-A25D-08	TCGA-BR-A4IZ-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ef5290da-bfcb-4880-9148-c8d5d1a6a4ac	f814337f-39ee-4808-b2fa-29b10610254f	g.chr4:153691406A>C	uc003imy.2	-	2	1533	c.751T>G	c.(751-753)TGT>GGT	p.C251G		NM_145720	NP_663772	Q8IY51	TIGD4_HUMAN	tigger transposable element derived 4	251	DDE.				regulation of transcription, DNA-dependent	chromosome, centromeric region|nucleus	chromatin binding|DNA binding			ovary(1)	1	all_hematologic(180;0.093)					GCTTCATAACACACAGGCAAT	0.418000												
RXFP3	51289	broad.mit.edu	37	5	33936904	33936904	+	Missense_Mutation	SNP	A	A	C			TCGA-BR-A4IZ-01A-32D-A25D-08	TCGA-BR-A4IZ-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ef5290da-bfcb-4880-9148-c8d5d1a6a4ac	f814337f-39ee-4808-b2fa-29b10610254f	g.chr5:33936904A>C	uc003jic.1	+	1	416	c.59A>C	c.(58-60)AAG>ACG	p.K20T		NM_016568	NP_057652	Q9NSD7	RL3R1_HUMAN	relaxin/insulin-like family peptide receptor 3	20	Extracellular (Potential).					integral to plasma membrane	N-formyl peptide receptor activity			upper_aerodigestive_tract(1)	1						GGCGGGGACAAGCTAGCAGAA	0.597000												
DOCK2	1794	broad.mit.edu	37	5	169474616	169474616	+	Missense_Mutation	SNP	C	C	T			TCGA-BR-A4IZ-01A-32D-A25D-08	TCGA-BR-A4IZ-10A-01D-A25E-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ef5290da-bfcb-4880-9148-c8d5d1a6a4ac	f814337f-39ee-4808-b2fa-29b10610254f	g.chr5:169474616C>T	uc003maf.2	+	40	4149	c.4069C>T	c.(4069-4071)CGG>TGG	p.R1357W	DOCK2_uc011der.1_RNA|DOCK2_uc010jjm.2_Missense_Mutation_p.R849W	NM_004946	NP_004937	Q92608	DOCK2_HUMAN	dedicator of cytokinesis 2	1357	DHR-2.|Interaction with CRKL.				actin cytoskeleton organization|regulation of defense response to virus by virus|viral reproduction	cytoskeleton|cytosol|endomembrane system|membrane	electron carrier activity|GTP binding|GTPase binding|heme binding|Rac guanyl-nucleotide exchange factor activity|T cell receptor binding			ovary(5)|pancreas(2)	7	Renal(175;0.000159)|Lung NSC(126;0.0221)|all_lung(126;0.0337)	Medulloblastoma(196;0.0399)|all_neural(177;0.0966)	Kidney(164;7.53e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)			CTCCTTCCTGCGGGTGAGTTT	0.542000