Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
KIAA1211	0	genome.wustl.edu	37	4	57180907	57180907	+	Silent	SNP	G	G	A			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	4	57180907	57180907	G	A	SNP	KIAA1211	ENST00000504228	human	ensembl	74_37	+1	known	silent	c.1239	p.E413	0.000	NULL	NULL	-	no_errors	KIAA1211	HGNC	ENSG00000109265	tier1	-	-	131	0	0.00	31	66	68.04	48	0	0.00	14	40	74.07
PKD1L1	0	genome.wustl.edu	37	7	47945469	47945469	+	Missense_Mutation	SNP	T	T	C			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	7	47945469	47945469	T	C	SNP	PKD1L1	ENST00000289672	human	ensembl	74_37	-1	known	missense	c.1493	p.H498R	0.000	NULL	pfam_PKD/REJ-like,pfam_PKD1_2_channel,pfam_PKD_dom,pfam_PLAT/LH2_dom,superfamily_Lipase_LipOase,superfamily_PKD_dom,smart_PKD/Chitinase_dom,smart_PLAT/LH2_dom,pfscan_PKD_dom,pfscan_PLAT/LH2_dom,pfscan_REJ-like	-	no_errors	PKD1L1	HGNC	ENSG00000158683	tier1	rs200709779	GMAF=0	60	0	0.00	97	57	37.01	89	0	0.00	63	55	46.61
DH10	0	genome.wustl.edu	37	12	124358165	124358165	+	Missense_Mutation	SNP	G	G	C			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	12	124358165	124358165	G	C	SNP	DH10	ENST00000409039	human	ensembl	74_37	+1	known	missense	c.7492	p.E2498Q	1.000	pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_Dynein_heavy_dom-1,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,superfamily_PyrdxlP-dep_Trfase,smart_AAA+_ATPase	-	no_errors	DH10	HGNC	ENSG00000197653	tier1	-	-	92	0	0.00	41	28	40.58	102	0	0.00	107	46	30.07
SYT16	0	genome.wustl.edu	37	14	62567269	62567269	+	Silent	SNP	C	C	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	14	62567269	62567269	C	T	SNP	SYT16	ENST00000430451	human	ensembl	74_37	+1	novel	silent	c.1782	p.S594	0.929	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom	-	no_errors	SYT16	HGNC	ENSG00000139973	tier1	-	-	79	0	0.00	15	34	69.39	104	0	0.00	29	64	68.82
GPRC6A	0	genome.wustl.edu	37	6	117127901	117127901	+	Missense_Mutation	SNP	C	C	A			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	6	117127901	117127901	C	A	SNP	GPRC6A	ENST00000310357	human	ensembl	74_37	-1	known	missense	c.967	p.V323F	0.995	pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I	pfam_GPCR_3_C,pfam_ANF_lig-bd_rcpt,pfam_GPCR_3_9-Cys_dom,superfamily_Peripla_BP_I,pfscan_GPCR_3_C,prints_GPCR_3,prints_GPCR_3_vmron_rcpt_2	-	no_errors	GPRC6A	HGNC	ENSG00000173612	tier1	-	-	35	0	0.00	19	16	45.71	128	0	0.00	60	38	38.78
MAGEC1	0	genome.wustl.edu	37	X	140996475	140996475	+	Silent	SNP	C	C	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	X	140996475	140996475	C	T	SNP	MAGEC1	ENST00000285879	human	ensembl	74_37	+1	known	silent	c.3285	p.V1095	0.000	pfscan_MAGE	pfam_MAGE,pfscan_MAGE	-	no_errors	MAGEC1	HGNC	ENSG00000155495	tier1	-	-	34	0	0.00	27	9	25.00	58	0	0.00	44	33	42.31
CTRB1	0	genome.wustl.edu	37	16	75257097	75257097	+	Nonsense_Mutation	SNP	C	C	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	16	75257097	75257097	C	T	SNP	CTRB1	ENST00000361017	human	ensembl	74_37	+1	known	nonsense	c.295	p.Q99*	0.997	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1,prints_Peptidase_S1A	-	no_errors	CTRB1	HGNC	ENSG00000168925	tier1	-	-	111	0	0.00	31	22	41.51	12	0	0.00	13	5	27.78
TRIM27	0	genome.wustl.edu	37	6	28888004	28888004	+	Missense_Mutation	SNP	C	C	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	6	28888004	28888004	C	T	SNP	TRIM27	ENST00000377199	human	ensembl	74_37	-1	known	missense	c.532	p.E178K	1.000	NULL	pfam_SPRY_rcpt,pfam_Znf_B-box,pfam_Znf_C3HC4_RING-type,superfamily_ConA-like_lec_gl_sf,smart_Znf_RING,smart_Znf_B-box,smart_PRY,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Znf_B-box,pfscan_Znf_RING,prints_Butyrophylin,prints_Znf_B-box_chordata	-	no_errors	TRIM27	HGNC	ENSG00000204713	tier1	-	-	35	0	0.00	20	7	25.93	117	0	0.00	76	13	14.61
FGFR4	0	genome.wustl.edu	37	5	176524620	176524620	+	Silent	SNP	C	C	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	5	176524620	176524620	C	T	SNP	FGFR4	ENST00000292408	human	ensembl	74_37	+1	known	silent	c.2352	p.H784	0.977	pirsf_FGF_rcpt_fam	pirsf_FGF_rcpt_fam,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Ig_I-set,pfam_Immunoglobulin,superfamily_Kinase-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	FGFR4	HGNC	ENSG00000160867	tier1	rs199622668	GMAF=0.0005	44	0	0.00	11	17	60.71	45	0	0.00	11	28	71.79
OR8K3	0	genome.wustl.edu	37	11	56086342	56086342	+	Missense_Mutation	SNP	T	T	G			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	11	56086342	56086342	T	G	SNP	OR8K3	ENST00000312711	human	ensembl	74_37	+1	known	missense	c.560	p.L187W	0.012	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR8K3	HGNC	ENSG00000181689	tier1	-	-	70	0	0.00	19	20	51.28	87	0	0.00	37	42	53.16
INSC	0	genome.wustl.edu	37	11	15243108	15243108	+	Missense_Mutation	SNP	C	C	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	11	15243108	15243108	C	T	SNP	INSC	ENST00000379554	human	ensembl	74_37	+1	known	missense	c.1046	p.A349V	1.000	superfamily_ARM-type_fold,smart_Armadillo	superfamily_ARM-type_fold,smart_Armadillo	-	no_errors	INSC	HGNC	ENSG00000188487	tier1	-	-	57	0	0.00	17	9	34.62	17	0	0.00	20	5	20.00
SUFU	0	genome.wustl.edu	37	10	104357026	104357026	+	Nonsense_Mutation	SNP	C	C	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	10	104357026	104357026	C	T	SNP	SUFU	ENST00000369902	human	ensembl	74_37	+1	known	nonsense	c.886	p.Q296*	1.000	pfam_SUFU_C,pirsf_Suppressor_of_fused_euk	pfam_SUFU_C,pfam_SUFU-like_domain,pirsf_Suppressor_of_fused_euk	-	no_errors	SUFU	HGNC	ENSG00000107882	tier1	-	-	56	0	0.00	17	17	50.00	32	0	0.00	10	18	64.29
MFSD10	0	genome.wustl.edu	37	4	2934379	2934379	+	Missense_Mutation	SNP	G	G	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	4	2934379	2934379	G	T	SNP	MFSD10	ENST00000329687	human	ensembl	74_37	-1	known	missense	c.479	p.S160Y	1.000	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	MFSD10	HGNC	ENSG00000109736	tier1	-	-	41	0	0.00	13	5	27.78	26	0	0.00	17	2	10.53
GS	0	genome.wustl.edu	37	20	57466892	57466892	+	Silent	SNP	C	C	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	20	57466892	57466892	C	T	SNP	GS	ENST00000354359	human	ensembl	74_37	+1	known	silent	c.111	p.Y37	0.996	pfam_Gprotein_alpha_su,superfamily_P-loop_NTPase,smart_Gprotein_alpha_su	pfam_Gprotein_alpha_su,pfam_Small_GTPase_ARF/SAR,superfamily_P-loop_NTPase,superfamily_GproteinA_insert,smart_Gprotein_alpha_su,prints_Gprotein_alpha_S,prints_Gprotein_alpha_su	-	no_errors	GS	HGNC	ENSG00000087460	tier1	-	-	35	0	0.00	20	25	55.56	15	0	0.00	11	14	56.00
OR4F6	0	genome.wustl.edu	37	15	102346825	102346825	+	Silent	SNP	A	A	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	15	102346825	102346825	A	T	SNP	OR4F6	ENST00000328882	human	ensembl	74_37	+1	known	silent	c.903	p.R301	0.000	NULL	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4F6	HGNC	ENSG00000184140	tier1	-	-	56	0	0.00	25	34	57.63	63	0	0.00	12	31	72.09
GUCY2EP	0	genome.wustl.edu	37	11	76414357	76414357	+	R	SNP	G	G	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	11	76414357	76414357	G	T	SNP	GUCY2EP	ENST00000526984	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	GUCY2EP	HGNC	ENSG00000204529	tier1	-	-	42	0	0.00	34	4	10.53	118	0	0.00	78	27	25.71
KCNH5	0	genome.wustl.edu	37	14	63269288	63269288	+	Missense_Mutation	SNP	G	G	C			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	14	63269288	63269288	G	C	SNP	KCNH5	ENST00000322893	human	ensembl	74_37	-1	known	missense	c.1581	p.I527M	1.000	superfamily_cNMP-bd-like,prints_K_chnl_volt-dep_EAG	pfam_Ion_trans_dom,pfam_2pore_dom_K_chnl_dom,pfam_cNMP-bd_dom,pfam_PAS_fold,superfamily_cNMP-bd-like,superfamily_PAS,smart_PAC,smart_cNMP-bd_dom,prints_K_chnl_volt-dep_EAG,prints_K_chnl_volt-dep_EAG/ELK/ERG,prints_K_chnl_volt-dep_ERG,pfscan_cNMP-bd_dom,pfscan_PAS-assoc_C,tigrfam_PAS	-	no_errors	KCNH5	HGNC	ENSG00000140015	tier1	-	-	24	0	0.00	6	11	64.71	59	0	0.00	12	26	68.42
RYR1	0	genome.wustl.edu	37	19	39010003	39010003	+	Missense_Mutation	SNP	G	G	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	19	39010003	39010003	G	T	SNP	RYR1	ENST00000359596	human	ensembl	74_37	+1	known	missense	c.10168	p.G3390C	1.000	NULL	pfam_Ca-rel_channel,pfam_Ryanodine_rcpt,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ConA-like_lec_gl_sf,superfamily_MG_RAP_rcpt_1,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_MIR_motif	-	no_errors	RYR1	HGNC	ENSG00000196218	tier1	-	-	53	0	0.00	36	7	16.28	22	0	0.00	27	7	20.59
PDE1A	0	genome.wustl.edu	37	2	183066503	183066503	+	Missense_Mutation	SNP	G	G	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	2	183066503	183066503	G	T	SNP	PDE1A	ENST00000456212	human	ensembl	74_37	-1	known	missense	c.964	p.L322I	0.999	pfam_PDEase_catalytic_dom,smart_HD/PDEase_dom	pfam_PDEase_catalytic_dom,pfam_PDEase_N,superfamily_GRIP,smart_HD/PDEase_dom,prints_PDEase	-	no_errors	PDE1A	HGNC	ENSG00000115252	tier1	-	-	42	0	0.00	51	9	15.00	94	0	0.00	64	18	21.95
FLRT2	0	genome.wustl.edu	37	14	86092517	86092517	+	R	SNP	G	G	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	14	86092517	86092517	G	T	SNP	FLRT2	ENST00000553650	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.000	-	-	-	no_errors	FLRT2	HGNC	ENSG00000185070	tier1	-	-	37	0	0.00	10	21	67.74	99	0	0.00	31	61	66.30
SAMHD1	0	genome.wustl.edu	37	20	35545356	35545356	+	Missense_Mutation	SNP	C	C	A			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	20	35545356	35545356	C	A	SNP	SAMHD1	ENST00000262878	human	ensembl	74_37	-1	known	missense	c.949	p.A317S	1.000	pfam_HD_domain,smart_HD/PDEase_dom	pfam_HD_domain,pfam_SAM_2,pfam_SAM_type1,superfamily_SAM/pointed,smart_SAM,smart_HD/PDEase_dom,pfscan_SAM	-	no_errors	SAMHD1	HGNC	ENSG00000101347	tier1	-	-	72	0	0.00	29	53	64.63	101	1	0.98	32	63	66.32
AQP4	0	genome.wustl.edu	37	18	24442131	24442131	+	R	SNP	A	A	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	18	24442131	24442131	A	T	SNP	AQP4	ENST00000583022	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.013	-	-	-	no_errors	AQP4	HGNC	ENSG00000171885	tier1	-	-	30	0	0.00	25	9	26.47	69	0	0.00	47	34	41.98
ACSM5	0	genome.wustl.edu	37	16	20448601	20448601	+	Missense_Mutation	SNP	G	G	A			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	16	20448601	20448601	G	A	SNP	ACSM5	ENST00000331849	human	ensembl	74_37	+1	known	missense	c.1448	p.G483E	1.000	pfam_AMP-dep_Synth/Lig	pfam_AMP-dep_Synth/Lig	-	no_errors	ACSM5	HGNC	ENSG00000183549	tier1	-	-	110	0	0.00	59	12	16.90	84	0	0.00	64	20	23.81
SPOCK3	0	genome.wustl.edu	37	4	167983668	167983668	+	Missense_Mutation	SNP	C	C	A			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	4	167983668	167983668	C	A	SNP	SPOCK3	ENST00000357154	human	ensembl	74_37	-1	known	missense	c.219	p.W73C	1.000	NULL	pfam_SPARC/Testican_Ca-bd-dom,pfam_Thyroglobulin_1,pfam_Kazal_dom,superfamily_Thyroglobulin_1,smart_Kazal_dom,smart_Thyroglobulin_1,pfscan_Thyroglobulin_1	-	no_errors	SPOCK3	HGNC	ENSG00000196104	tier1	-	-	97	0	0.00	135	80	37.21	107	0	0.00	49	15	23.44
PCDHB12	0	genome.wustl.edu	37	5	140588657	140588657	+	Missense_Mutation	SNP	T	T	C			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	5	140588657	140588657	T	C	SNP	PCDHB12	ENST00000239450	human	ensembl	74_37	+1	known	missense	c.178	p.S60P	0.006	pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDHB12	HGNC	ENSG00000120328	tier1	-	-	74	0	0.00	46	29	38.67	84	0	0.00	48	22	31.43
ENDOU	0	genome.wustl.edu	37	12	48110109	48110109	+	Missense_Mutation	SNP	T	T	G			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	12	48110109	48110109	T	G	SNP	ENDOU	ENST00000229003	human	ensembl	74_37	-1	known	missense	c.602	p.E201A	1.000	pfam_Endoribonuclease_XendoU	pfam_Endoribonuclease_XendoU,pfam_Somatomedin_B_dom,smart_Somatomedin_B_dom,pfscan_Somatomedin_B_dom,prints_Somatomedin_B_chordata	-	no_errors	ENDOU	HGNC	ENSG00000111405	tier1	-	-	39	0	0.00	16	16	48.48	17	0	0.00	21	5	19.23
SLC9A4	0	genome.wustl.edu	37	2	103148889	103148889	+	Missense_Mutation	SNP	G	G	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	2	103148889	103148889	G	T	SNP	SLC9A4	ENST00000295269	human	ensembl	74_37	+1	known	missense	c.2139	p.M713I	0.976	NULL	pfam_Cation/H_exchanger,prints_NaH_exchanger,prints_Na/H_exchanger_2,tigrfam_NaH_exchanger	-	no_errors	SLC9A4	HGNC	ENSG00000180251	tier1	-	-	49	0	0.00	31	17	35.42	156	0	0.00	94	45	32.37
ULBP1	0	genome.wustl.edu	37	6	150290442	150290442	+	Nonsense_Mutation	SNP	A	A	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	6	150290442	150290442	A	T	SNP	ULBP1	ENST00000229708	human	ensembl	74_37	+1	known	nonsense	c.571	p.K191*	0.000	pfam_MHC_I_a_a1/a2,superfamily_MHC_I/II-like_Ag-recog	pfam_MHC_I_a_a1/a2,superfamily_MHC_I/II-like_Ag-recog	-	no_errors	ULBP1	HGNC	ENSG00000111981	tier1	-	-	29	0	0.00	37	4	9.76	71	0	0.00	62	8	11.43
DLGAP1	0	genome.wustl.edu	37	18	3708389	3708389	+	R	DEL	G	G	-			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	18	3708389	3708389	G	-	DEL	DLGAP1	ENST00000498188	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	DLGAP1	HGNC	ENSG00000170579	tier1			48	0	0.00	30	9	23.08	111	0	0.00	80	27	25.23
TTLL5	0	genome.wustl.edu	37	14	76246006	76246011	+	In_Frame_Del	DEL	AAGAAC	AAGAAC	-			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	AAGAAC	AAGAAC	AAGAAC	-	AAGAAC	AAGAAC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	14	76246006	76246011	AAGAAC	-	DEL	TTLL5	ENST00000298832	human	ensembl	74_37	+1	known	in_frame_del	c.2476_2481	p.KN826in_frame_del	0.997:1.000:0.997:0.983:1.000:1.000	NULL	pfam_TTL/TTLL_fam	-	no_errors	TTLL5	HGNC	ENSG00000119685	tier1			152	0	0.00	37	50	57.47	152	0	0.00	37	50	57.47
CR1	0	genome.wustl.edu	37	1	207753676	207753676	+	Silent	SNP	T	T	C			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	1	207753676	207753676	T	C	SNP	CR1	ENST00000367049	human	ensembl	74_37	+1	known	silent	c.5028	p.C1676	1.000	pfam_Sushi_SCR_CCP,superfamily_Sushi_SCR_CCP,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP	pfam_Sushi_SCR_CCP,superfamily_Sushi_SCR_CCP,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP	-	no_errors	CR1	HGNC	ENSG00000203710	tier1	-	-	142	0	0.00	34	40	54.05	17	0	0.00	1	10	90.91
MYH14	0	genome.wustl.edu	37	19	50760604	50760604	+	Missense_Mutation	SNP	C	C	A			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	19	50760604	50760604	C	A	SNP	MYH14	ENST00000262269	human	ensembl	74_37	+1	known	missense	c.2093	p.P698Q	0.098	pfam_Myosin_head_motor_dom,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom	pfam_Myosin_head_motor_dom,pfam_Myosin_tail,pfam_Myosin_N,superfamily_P-loop_NTPase,superfamily_Prefoldin,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYH14	HGNC	ENSG00000105357	tier1	-	-	50	0	0.00	17	15	46.88	23	0	0.00	3	11	78.57
NR0B1	0	genome.wustl.edu	37	X	30326654	30326654	+	Missense_Mutation	SNP	T	T	C			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	X	30326654	30326654	T	C	SNP	NR0B1	ENST00000378970	human	ensembl	74_37	-1	known	missense	c.827	p.Q276R	1.000	superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core,prints_Str_hrmn_rcpt	pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core,prints_Str_hrmn_rcpt	-	no_errors	NR0B1	HGNC	ENSG00000169297	tier1	-	-	46	0	0.00	8	37	82.22	9	0	0.00	4	10	71.43
ERN1	0	genome.wustl.edu	37	17	62133221	62133223	+	In_Frame_Del	DEL	GCT	GCT	-			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	GCT	GCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	17	62133221	62133223	GCT	-	DEL	ERN1	ENST00000433197	human	ensembl	74_37	-1	known	in_frame_del	c.1486_1484	p.Q495in_frame_del	0.999:0.998:0.998	NULL	pfam_Prot_kinase_dom,pfam_KEN_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Quinonprotein_ADH-like_supfam,smart_PQQ_beta_propeller_repeat,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_PUG-dom,pfscan_Prot_kinase_dom	-	no_errors	ERN1	HGNC	ENSG00000178607	tier1			19	0	0.00	14	2	12.50	10	0	0.00	5	1	16.67
FBXW5	0	genome.wustl.edu	37	9	139835416	139835417	+	Frame_Shift_Del	DEL	GC	GC	-			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	GC	GC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	9	139835416	139835417	GC	-	DEL	FBXW5	ENST00000325285	human	ensembl	74_37	-1	known	frame_shift_del	c.1665_1664	p.R555fs	0.927:0.986	NULL	pfam_WD40_repeat,pfam_F-box_dom,superfamily_Quinoprot_gluc/sorb_DH,superfamily_F-box_dom,smart_F-box_dom,smart_WD40_repeat,pfscan_F-box_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	FBXW5	HGNC	ENSG00000159069	tier1			79	0	0.00	17	2	10.53	10	0	0.00	7	0	0.00
KRBA1	0	genome.wustl.edu	37	7	149430495	149430495	+	Missense_Mutation	SNP	G	G	C			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	7	149430495	149430495	G	C	SNP	KRBA1	ENST00000255992	human	ensembl	74_37	+1	known	missense	c.2449	p.A817P	0.000	NULL	NULL	-	no_errors	KRBA1	HGNC	ENSG00000133619	tier1	-	-	61	0	0.00	37	21	35.59	7	0	0.00	3	0	0.00
CCNL2	0	genome.wustl.edu	37	1	1334664	1334666	+	In_Frame_Del	DEL	GCC	GCC	-			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	GCC	GCC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	1	1334664	1334666	GCC	-	DEL	CCNL2	ENST00000400809	human	ensembl	74_37	-1	known	in_frame_del	c.23_21	p.A8in_frame_del	0.005:0.003:0.058	pirsf_Cyclin_L	pfam_Cyclin_N,pfam_Cyclin_C-dom,superfamily_Cyclin-like,smart_Cyclin-like,pirsf_Cyclin_L	-	no_errors	CCNL2	HGNC	ENSG00000221978	tier1			27	0	0.00	7	2	22.22	0	0	0.00	1	0	0.00
CYP2F1	0	genome.wustl.edu	37	19	41630690	41630690	+	Missense_Mutation	SNP	C	C	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	19	41630690	41630690	C	T	SNP	CYP2F1	ENST00000331105	human	ensembl	74_37	+1	known	missense	c.1031	p.A344V	0.000	pfam_Cyt_P450,superfamily_Cyt_P450	pfam_Cyt_P450,superfamily_Cyt_P450,prints_Cyt_P450_E_grp-I,prints_Cyt_P450_CYP2_fam,prints_Cyt_P450,prints_Cyt_P450_E_grp-IV,prints_Cyt_P450_B	-	no_errors	CYP2F1	HGNC	ENSG00000197446	tier1	-	-	34	0	0.00	19	6	24.00	0	0	0.00	0	0	0.00
ENSG00000221684	0	genome.wustl.edu	37	X	70979276	70979276	+	R	SNP	A	A	G			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	X	70979276	70979276	A	G	SNP	ENSG00000221684	ENST00000408757	human	ensembl	74_37	-1	novel	rna	NULL	NULL	0.001	-	-	-	no_errors	BX276092.1	Clone_based_ensembl_gene	ENSG00000221684	tier1	rs67643106	-	41	0	0.00	30	4	11.76	1	0	0.00	3	0	0.00
ENSG00000264299	0	genome.wustl.edu	37	11	125828460	125828461	+	R	INS	-	-	TATATGTG			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	11	125828460	125828461	-	TATATGTG	INS	ENSG00000264299	ENST00000582823	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.301:0.221	-	-	-	no_errors	RP11-680F20.12	Clone_based_vega_gene	ENSG00000264299	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
ENSG00000266657	0	genome.wustl.edu	37	1	142653541	142653541	+	R	SNP	T	T	C			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	1	142653541	142653541	T	C	SNP	ENSG00000266657	ENST00000580249	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.000	-	-	-	no_errors	AL583842.3	Clone_based_ensembl_gene	ENSG00000266657	tier1	-	-	143	0	0.00	79	31	27.93	0	0	0.00	0	0	0.00
NUMBL	0	genome.wustl.edu	37	19	41173893	41173898	+	In_Frame_Del	DEL	TGCTGT	TGCTGT	-			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	TGCTGT	TGCTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	19	41173893	41173898	TGCTGT	-	DEL	NUMBL	ENST00000252891	human	ensembl	74_37	-1	known	in_frame_del	c.1310_1305	p.QQ439in_frame_del	1.000:1.000:1.000:1.000:1.000:0.998	pirsf_Numb/numb-like	pfam_Numb_domain,pfam_PTB/PI_dom,pfam_PTB,smart_PTB/PI_dom,pirsf_Numb/numb-like,pfscan_PTB/PI_dom	-	no_errors	NUMBL	HGNC	ENSG00000105245	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
MAMLD1	0	genome.wustl.edu	37	X	149671639	149671639	+	Missense_Mutation	SNP	G	G	T			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	X	149671639	149671639	G	T	SNP	MAMLD1	ENST00000262858	human	ensembl	74_37	+1	known	missense	c.2136	p.E712D	1.000	NULL	NULL	-	no_errors	MAMLD1	HGNC	ENSG00000013619	tier1	-	-	47	0	0.00	9	14	60.87	2	0	0.00	0	2	100.00
GRK4	0	genome.wustl.edu	37	4	3015469	3015470	+	Frame_Shift_Ins	INS	-	-	A			TCGA-X9-A973-01A-11D-A387-09	TCGA-X9-A973-10A-01D-A38A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	231a60ba-0cbf-4e49-80b9-fb79251a0329	3a81eddf-cc20-47e1-ba2e-5bc21240b8d9	4	3015469	3015470	-	A	INS	GRK4	ENST00000398052	human	ensembl	74_37	+1	known	frame_shift_ins	c.655_656	p.R222fs	1.000:1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_RGS_dom,superfamily_Kinase-like_dom,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,pfscan_Regulat_G_prot_signal_superfam,pfscan_Prot_kinase_dom,prints_GPCR_kinase	-	no_errors	GRK4	HGNC	ENSG00000125388	tier1			50	0	0.00	53	5	8.62	49	0	0.00	31	2	6.06