Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
CHD7	0	genome.wustl.edu	37	8	61655261	61655261	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	8	61655261	61655261	G	T	SNP	CHD7	ENST00000423902	human	ensembl	74_37	+1	known	missense	c.1270	p.V424F	1.000	NULL	pfam_SNF2_N,pfam_BRK_domain,pfam_Chromo_domain,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Chromodomain-like,smart_Chromo_domain/shadow,smart_Helicase_ATP-bd,smart_Helicase_C,smart_BRK_domain,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_Chromo_domain/shadow	-	no_errors	CHD7	HGNC	ENSG00000171316	tier1	-	-	55	0	0.00	40	26	39.39	109	0	0.00	73	56	43.41
KDM4A	0	genome.wustl.edu	37	1	44132716	44132716	+	Missense_Mutation	SNP	A	A	G			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	1	44132716	44132716	A	G	SNP	KDM4A	ENST00000372396	human	ensembl	74_37	+1	known	missense	c.869	p.N290S	1.000	pfam_JmjC_dom,smart_JmjC_dom,pfscan_JmjC_dom	pfam_JmjC_dom,pfam_TF_JmjN,superfamily_Znf_FYVE_PHD,smart_TF_JmjN,smart_JmjC_dom,smart_Znf_PHD,smart_Tudor,pfscan_TF_JmjN,pfscan_JmjC_dom	-	no_errors	KDM4A	HGNC	ENSG00000066135	tier1	-	-	40	0	0.00	4	25	86.21	120	0	0.00	15	47	75.81
SGK223	0	genome.wustl.edu	37	8	8235488	8235488	+	Missense_Mutation	SNP	C	C	G			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	8	8235488	8235488	C	G	SNP	SGK223	ENST00000330777	human	ensembl	74_37	-1	known	missense	c.431	p.G144A	0.007	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,pfscan_Prot_kinase_dom	-	no_errors	SGK223	Uniprot_gn	ENSG00000182319	tier1	-	-	60	0	0.00	65	46	41.44	66	0	0.00	23	19	45.24
LPCAT1	0	genome.wustl.edu	37	5	1463892	1463892	+	Silent	SNP	C	C	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	5	1463892	1463892	C	T	SNP	LPCAT1	ENST00000283415	human	ensembl	74_37	-1	known	silent	c.1479	p.P493	0.004	NULL	pfam_Plipid/glycerol_acylTrfase,smart_Plipid/glycerol_acylTrfase,smart_EF_hand_dom,pfscan_EF_hand_dom	-	no_errors	LPCAT1	HGNC	ENSG00000153395	tier1	-	-	67	0	0.00	78	14	15.22	114	0	0.00	105	21	16.67
RB1	0	genome.wustl.edu	37	13	48955538	48955538	+	Nonsense_Mutation	SNP	C	C	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	13	48955538	48955538	C	T	SNP	RB1	ENST00000267163	human	ensembl	74_37	+1	known	nonsense	c.1654	p.R552*	1.000	pfam_RB_A,superfamily_Cyclin-like	pfam_RB_C,pfam_RB_A,pfam_RB_B,pfam_RB_N,superfamily_Cyclin-like,smart_Cyclin-like	-	no_errors	RB1	HGNC	ENSG00000139687	tier1	rs121913303	-	48	0	0.00	11	26	70.27	73	0	0.00	20	38	65.52
LRRK1	0	genome.wustl.edu	37	15	101609095	101609095	+	R	SNP	G	G	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	15	101609095	101609095	G	A	SNP	LRRK1	ENST00000532145	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	LRRK1	HGNC	ENSG00000154237	tier1	-	-	43	0	0.00	34	27	43.55	47	0	0.00	12	21	63.64
OR9G4	0	genome.wustl.edu	37	11	56510853	56510853	+	Silent	SNP	C	C	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	11	56510853	56510853	C	T	SNP	OR9G4	ENST00000302957	human	ensembl	74_37	-1	known	silent	c.435	p.L145	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR9G4	HGNC	ENSG00000172457	tier1	-	-	52	0	0.00	42	23	34.85	109	0	0.00	56	23	29.11
GNPTAB	0	genome.wustl.edu	37	12	102161768	102161768	+	Missense_Mutation	SNP	A	A	C			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	12	102161768	102161768	A	C	SNP	GNPTAB	ENST00000549940	human	ensembl	74_37	-1	known	missense	c.1455	p.F485L	0.000	NULL	pfam_Notch_dom,pfam_DUF3184,superfamily_Notch_dom,smart_Notch_dom,pfscan_Notch_dom	-	no_errors	GNPTAB	HGNC	ENSG00000111670	tier1	-	-	43	0	0.00	34	33	49.25	118	0	0.00	67	81	54.73
GIF	0	genome.wustl.edu	37	11	59603420	59603420	+	Missense_Mutation	SNP	T	T	C			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	11	59603420	59603420	T	C	SNP	GIF	ENST00000257248	human	ensembl	74_37	-1	known	missense	c.934	p.I312V	0.997	pfam_Cbl-bd_transpt_euk	pfam_Cbl-bd_transpt_euk	-	no_errors	GIF	HGNC	ENSG00000134812	tier1	-	-	39	0	0.00	56	35	38.46	98	0	0.00	41	38	48.10
NMRK2	0	genome.wustl.edu	37	19	3939924	3939924	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	19	3939924	3939924	G	A	SNP	NMRK2	ENST00000168977	human	ensembl	74_37	+1	known	missense	c.350	p.R117Q	0.594	superfamily_P-loop_NTPase	superfamily_P-loop_NTPase	-	no_errors	NMRK2	HGNC	ENSG00000077009	tier1	rs140113877	-	76	0	0.00	76	22	22.45	95	1	1.04	92	30	24.39
CHR5	0	genome.wustl.edu	37	15	78873234	78873234	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	15	78873234	78873234	G	A	SNP	CHR5	ENST00000299565	human	ensembl	74_37	+1	known	missense	c.188	p.R63H	1.000	pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,tigrfam_Neur_channel	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_Nicotinic_acetylcholine_rcpt,prints_Neur_channel,tigrfam_Neur_channel	-	no_errors	CHR5	HGNC	ENSG00000169684	tier1	rs202057419	-	100	0	0.00	82	62	43.06	67	0	0.00	47	22	31.88
POLN	0	genome.wustl.edu	37	4	2074696	2074696	+	Missense_Mutation	SNP	T	T	G			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	4	2074696	2074696	T	G	SNP	POLN	ENST00000382865	human	ensembl	74_37	-1	known	missense	c.2516	p.Q839P	1.000	pfam_D-dir_D_pol_A_palm_dom	pfam_D-dir_D_pol_A_palm_dom,superfamily_RNaseH-like_dom,smart_D-dir_D_pol_A_palm_dom,prints_D_polymerase_A	-	no_errors	POLN	HGNC	ENSG00000130997	tier1	-	-	58	0	0.00	55	45	45.00	52	0	0.00	19	16	45.71
ATP13A4	0	genome.wustl.edu	37	3	193174850	193174850	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	3	193174850	193174850	G	T	SNP	ATP13A4	ENST00000342695	human	ensembl	74_37	-1	known	missense	c.1854	p.D618E	0.031	pfam_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,tigrfam_ATPase_P-typ_Cation_typ_V,tigrfam_Cation_transp_P_typ_ATPase	pfam_ATPase_P-typ_transduc_dom_A,pfam_ATPase_P-typ_Cation_typ_V,pfam_HAD-like_dom,pfam_ATPase_P-typ_cation-transptr_N,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,smart_ATPase_P-typ_cation-transptr_N,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Cation_typ_V,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP13A4	HGNC	ENSG00000127249	tier1	-	-	36	0	0.00	30	18	37.50	112	1	0.88	50	49	49.49
DIAPH2	0	genome.wustl.edu	37	X	96354765	96354765	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	X	96354765	96354765	C	A	SNP	DIAPH2	ENST00000324765	human	ensembl	74_37	+1	known	missense	c.2320	p.L774I	1.000	pfam_FH2_Formin,smart_FH2_Formin	pfam_FH2_Formin,pfam_FH3_dom,pfam_GTPase-bd,pfam_Drf_DAD,superfamily_ARM-type_fold,smart_FH2_Formin	-	no_errors	DIAPH2	HGNC	ENSG00000147202	tier1	-	-	42	0	0.00	11	23	67.65	71	0	0.00	14	44	75.86
GRIA4	0	genome.wustl.edu	37	11	105483056	105483056	+	Missense_Mutation	SNP	A	A	G			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	11	105483056	105483056	A	G	SNP	GRIA4	ENST00000282499	human	ensembl	74_37	+1	known	missense	c.142	p.I48V	1.000	pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I	pfam_ANF_lig-bd_rcpt,pfam_Iontro_glu_rcpt,pfam_Glu_rcpt_Glu/Gly-bd,pfam_SBP_bac_3,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIA4	HGNC	ENSG00000152578	tier1	-	-	71	0	0.00	59	42	41.18	100	0	0.00	60	43	41.75
COQ5	0	genome.wustl.edu	37	12	120942762	120942762	+	Silent	SNP	G	G	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	12	120942762	120942762	G	A	SNP	COQ5	ENST00000288532	human	ensembl	74_37	-1	known	silent	c.706	p.L236	1.000	pfam_UbiE/COQ5_MeTrFase,pfam_Methyltransf_11,pfam_Methyltransf_12,tigrfam_UbiE/COQ5_MeTrFase	pfam_UbiE/COQ5_MeTrFase,pfam_Methyltransf_11,pfam_Methyltransf_12,tigrfam_UbiE/COQ5_MeTrFase	-	no_errors	COQ5	HGNC	ENSG00000110871	tier1	-	-	63	0	0.00	24	20	45.45	187	0	0.00	68	79	53.38
OR10Q1	0	genome.wustl.edu	37	11	57996303	57996303	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	11	57996303	57996303	C	A	SNP	OR10Q1	ENST00000316770	human	ensembl	74_37	-1	known	missense	c.45	p.E15D	0.807	NULL	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR10Q1	HGNC	ENSG00000180475	tier1	-	-	41	0	0.00	32	23	41.82	103	0	0.00	75	40	34.78
GABRR1	0	genome.wustl.edu	37	6	89895101	89895101	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	6	89895101	89895101	G	A	SNP	GABRR1	ENST00000454853	human	ensembl	74_37	-1	known	missense	c.724	p.R242W	1.000	pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,tigrfam_Neur_channel	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_GABAA_rcpt,prints_GABAAa_rho1_rcpt,prints_Neur_channel,prints_GABAAa_rho_rcpt,tigrfam_Neur_channel	-	no_errors	GABRR1	HGNC	ENSG00000146276	tier1	rs200602822	-	55	0	0.00	42	26	38.24	125	0	0.00	61	61	50.00
PENK	0	genome.wustl.edu	37	8	57353842	57353842	+	Missense_Mutation	SNP	T	T	C			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	8	57353842	57353842	T	C	SNP	PENK	ENST00000314922	human	ensembl	74_37	-1	known	missense	c.793	p.M265V	1.000	NULL	pfam_Opioid_neupept,prints_Proenkphlin_A,prints_Opioid_neupept	-	no_errors	PENK	HGNC	ENSG00000181195	tier1	-	-	83	0	0.00	42	27	38.57	158	0	0.00	93	58	38.41
TTN	0	genome.wustl.edu	37	2	179511230	179511230	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	2	179511230	179511230	C	T	SNP	TTN	ENST00000589042	human	ensembl	74_37	-1	putative	missense	c.40279	p.E13427K	0.999	superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_PPAK_motif,pfam_Titin_Z,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,superfamily_ARM-type_fold,superfamily_P-loop_NTPase,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	43	0	0.00	35	30	45.45	113	0	0.00	70	52	42.62
KIF25	0	genome.wustl.edu	37	6	168443353	168443353	+	Silent	SNP	G	G	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	6	168443353	168443353	G	A	SNP	KIF25	ENST00000354419	human	ensembl	74_37	+1	known	silent	c.942	p.P314	0.157	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,prints_Kinesin_motor_dom	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	KIF25	HGNC	ENSG00000125337	tier1	rs147561163	-	51	0	0.00	50	38	43.18	73	0	0.00	44	20	31.25
SYNPO	0	genome.wustl.edu	37	5	150028887	150028887	+	Silent	SNP	G	G	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	5	150028887	150028887	G	A	SNP	SYNPO	ENST00000394243	human	ensembl	74_37	+1	known	silent	c.1782	p.K594	0.235	NULL	NULL	-	no_errors	SYNPO	HGNC	ENSG00000171992	tier1	-	-	42	0	0.00	34	21	38.18	62	0	0.00	43	22	33.85
LRRC16B	0	genome.wustl.edu	37	14	24525877	24525877	+	Silent	SNP	C	C	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	14	24525877	24525877	C	T	SNP	LRRC16B	ENST00000342740	human	ensembl	74_37	+1	known	silent	c.912	p.L304	1.000	NULL	smart_Leu-rich_rpt_RNase_inh_sub-typ	-	no_errors	LRRC16B	HGNC	ENSG00000186648	tier1	-	-	52	0	0.00	40	28	41.18	69	0	0.00	30	36	54.55
ATRX	0	genome.wustl.edu	37	X	76763007	76763007	+	R	SNP	G	G	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	X	76763007	76763007	G	A	SNP	ATRX	ENST00000480283	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.075	-	-	-	no_errors	ATRX	HGNC	ENSG00000085224	tier1	-	-	50	0	0.00	9	38	80.85	67	0	0.00	13	33	71.74
POLE	0	genome.wustl.edu	37	12	133220026	133220026	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	12	133220026	133220026	G	A	SNP	POLE	ENST00000320574	human	ensembl	74_37	-1	known	missense	c.4411	p.R1471C	1.000	NULL	pfam_D_pol_e_suA_C,pfam_D-dir_D_pol_B_exonuc,pfam_D-dir_D_pol_B_multi_dom,pfam_3'-5'_exonuclease_PolB-like,superfamily_RNaseH-like_dom,smart_D-dir_D_pol_B	-	no_errors	POLE	HGNC	ENSG00000177084	tier1	-	-	44	0	0.00	34	26	43.33	129	1	0.77	63	38	37.62
TBX5	0	genome.wustl.edu	37	12	114836461	114836461	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	12	114836461	114836461	C	T	SNP	TBX5	ENST00000310346	human	ensembl	74_37	-1	known	missense	c.427	p.A143T	0.998	pfam_TF_T-box,superfamily_p53-like_TF_D-bd,smart_TF_T-box,pfscan_TF_T-box,prints_TF_T-box	pfam_TF_T-box,superfamily_p53-like_TF_D-bd,smart_TF_T-box,pfscan_TF_T-box,prints_TF_T-box	-	no_errors	TBX5	HGNC	ENSG00000089225	tier1	-	-	42	0	0.00	29	18	38.30	93	0	0.00	50	33	39.76
NEB	0	genome.wustl.edu	37	2	152527713	152527713	+	Silent	SNP	A	A	G			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	2	152527713	152527713	A	G	SNP	NEB	ENST00000397345	human	ensembl	74_37	-1	known	silent	c.4330	p.L1444	0.984	pfscan_Nebulin_35r-motif	pfam_Nebulin_35r-motif,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,superfamily_Adhesion_dom,superfamily_6-PGluconate_DH_C-like,smart_Nebulin_35r-motif,smart_SH3_domain,pfscan_Nebulin_35r-motif,pfscan_SH3_domain,prints_Nebulin	-	no_errors	NEB	HGNC	ENSG00000183091	tier1	-	-	100	0	0.00	135	19	12.34	100	0	0.00	97	28	22.40
TSPYL6	0	genome.wustl.edu	37	2	54483161	54483161	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	2	54483161	54483161	C	A	SNP	TSPYL6	ENST00000317802	human	ensembl	74_37	-1	known	missense	c.128	p.R43L	0.156	NULL	pfam_P_family	-	no_errors	TSPYL6	HGNC	ENSG00000178021	tier1	-	-	73	0	0.00	52	29	35.80	62	0	0.00	52	18	25.71
PLEKHO1	0	genome.wustl.edu	37	1	150131553	150131553	+	Silent	SNP	G	G	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	1	150131553	150131553	G	T	SNP	PLEKHO1	ENST00000025469	human	ensembl	74_37	+1	known	silent	c.963	p.T321	0.292	NULL	pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	-	no_errors	PLEKHO1	HGNC	ENSG00000023902	tier1	-	-	43	0	0.00	26	17	39.53	38	0	0.00	23	11	32.35
PDE7A	0	genome.wustl.edu	37	8	66701116	66701116	+	Splice_Site	SNP	C	C	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	8	66701116	66701116	C	T	SNP	PDE7A	ENST00000379419	human	ensembl	74_37	-1	known	splice_site	c.60+1	e1+1	1.000	-	-	-	no_errors	PDE7A	HGNC	ENSG00000205268	tier1	-	-	47	0	0.00	26	25	49.02	92	0	0.00	69	68	49.64
ABCB4	0	genome.wustl.edu	37	7	87069600	87069600	+	Missense_Mutation	SNP	T	T	C			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	7	87069600	87069600	T	C	SNP	ABCB4	ENST00000265723	human	ensembl	74_37	-1	known	missense	c.1475	p.Y492C	1.000	pfam_ABC_transporter-like,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like	pfam_ABC_transptr_TM_dom,pfam_ABC_transporter-like,pfam_ABC_ATPase_put,pfam_Zeta_toxin_domain,superfamily_P-loop_NTPase,superfamily_ABC1_TM_dom,smart_AAA+_ATPase,pfscan_ABC_transporter-like,pfscan_ABC1_TM_dom	-	no_errors	ABCB4	HGNC	ENSG00000005471	tier1	-	-	69	0	0.00	57	35	38.04	81	0	0.00	67	34	33.66
ZNF570	0	genome.wustl.edu	37	19	37975446	37975446	+	Silent	SNP	C	C	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	19	37975446	37975446	C	A	SNP	ZNF570	ENST00000330173	human	ensembl	74_37	+1	known	silent	c.922	p.R308	1.000	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF570	HGNC	ENSG00000171827	tier1	-	-	61	0	0.00	53	39	42.39	93	0	0.00	56	37	39.78
COL6A3	0	genome.wustl.edu	37	2	238253180	238253180	+	Missense_Mutation	SNP	A	A	G			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	2	238253180	238253180	A	G	SNP	COL6A3	ENST00000295550	human	ensembl	74_37	-1	known	missense	c.7481	p.V2494A	1.000	pfam_VWF_A,smart_VWF_A,pfscan_VWF_A	pfam_VWF_A,pfam_Collagen,pfam_Prot_inh_Kunz-m,superfamily_Prot_inh_Kunz-m,superfamily_Fibronectin_type3,smart_VWF_A,smart_Prot_inh_Kunz-m,pfscan_Fibronectin_type3,pfscan_VWF_A,pfscan_Prot_inh_Kunz-m,prints_Prot_inh_Kunz-m	-	no_errors	COL6A3	HGNC	ENSG00000163359	tier1	-	-	49	0	0.00	11	31	73.81	110	1	0.90	13	50	79.37
ATP2A2	0	genome.wustl.edu	37	12	110770407	110770407	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	12	110770407	110770407	C	A	SNP	ATP2A2	ENST00000539276	human	ensembl	74_37	+1	known	missense	c.1101	p.F367L	1.000	superfamily_ATPase_P-typ_cyto_domN,tigrfam_ATPase_P-typ_Ca-transp_IIA,tigrfam_Cation_transp_P_typ_ATPase	pfam_ATPase_P-typ_transduc_dom_A,pfam_ATPase_P-typ_cation-transptr_C,pfam_HAD-like_dom,pfam_ATPase_P-typ_cation-transptr_N,superfamily_ATPase_P-typ_cyto_domN,superfamily_HAD-like_dom,smart_ATPase_P-typ_cation-transptr_N,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Ca-transp_IIA,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP2A2	HGNC	ENSG00000174437	tier1	-	-	88	0	0.00	48	28	36.84	104	0	0.00	94	41	30.37
RAMP2-AS1	0	genome.wustl.edu	37	17	40913022	40913022	+	R	SNP	C	C	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	17	40913022	40913022	C	T	SNP	RAMP2-AS1	ENST00000360166	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.992	-	-	-	no_errors	RAMP2-AS1	HGNC	ENSG00000197291	tier1	-	-	12	0	0.00	12	14	53.85	42	0	0.00	32	9	21.95
DH9	0	genome.wustl.edu	37	17	11515104	11515104	+	Missense_Mutation	SNP	A	A	G			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	17	11515104	11515104	A	G	SNP	DH9	ENST00000579828	human	ensembl	74_37	+1	novel	missense	c.911	p.D304G	0.000	NULL	pfam_Dynein_heavy_dom-1	-	no_errors	DH9	HGNC	ENSG00000007174	tier1	-	-	66	0	0.00	400	49	10.91	142	0	0.00	413	52	11.16
PHKB	0	genome.wustl.edu	37	16	47533690	47533690	+	Missense_Mutation	SNP	C	C	G			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	16	47533690	47533690	C	G	SNP	PHKB	ENST00000299167	human	ensembl	74_37	+1	known	missense	c.190	p.Q64E	1.000	pfam_Glyco_hydro_15,superfamily_6-hairpin_glycosidase-like	pfam_Glyco_hydro_15,superfamily_6-hairpin_glycosidase-like	-	no_errors	PHKB	HGNC	ENSG00000102893	tier1	-	-	96	0	0.00	65	35	35.00	134	0	0.00	71	22	23.66
UBE2G2	0	genome.wustl.edu	37	21	46193533	46193533	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	21	46193533	46193533	C	T	SNP	UBE2G2	ENST00000345496	human	ensembl	74_37	-1	known	missense	c.314	p.S105N	1.000	pfam_UBQ-conjugat_E2,superfamily_UBQ-conjugating_enzyme/RWD,pfscan_UBQ-conjugat_E2	pfam_UBQ-conjugat_E2,superfamily_UBQ-conjugating_enzyme/RWD,pfscan_UBQ-conjugat_E2	-	no_errors	UBE2G2	HGNC	ENSG00000184787	tier1	-	-	40	0	0.00	23	32	58.18	26	0	0.00	15	14	48.28
GFI1B	0	genome.wustl.edu	37	9	135863692	135863692	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	9	135863692	135863692	G	T	SNP	GFI1B	ENST00000339463	human	ensembl	74_37	+1	known	missense	c.347	p.G116V	0.417	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	GFI1B	HGNC	ENSG00000165702	tier1	-	-	81	0	0.00	86	38	30.40	73	0	0.00	57	38	40.00
MTG2	0	genome.wustl.edu	37	20	60772864	60772864	+	R	SNP	G	G	C			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	20	60772864	60772864	G	C	SNP	MTG2	ENST00000461411	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	MTG2	HGNC	ENSG00000101181	tier1	-	-	44	0	0.00	51	7	12.07	139	0	0.00	108	22	16.92
MTF2	0	genome.wustl.edu	37	1	93585109	93585109	+	R	SNP	T	T	C			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	1	93585109	93585109	T	C	SNP	MTF2	ENST00000468457	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.071	-	-	-	no_errors	MTF2	HGNC	ENSG00000143033	tier1	-	-	18	0	0.00	22	11	33.33	53	0	0.00	40	23	36.51
GNPTAB	0	genome.wustl.edu	37	12	102161854	102161856	+	In_Frame_Del	DEL	TAC	TAC	-			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	TAC	TAC	TAC	-	TAC	TAC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	12	102161854	102161856	TAC	-	DEL	GNPTAB	ENST00000299314	human	ensembl	74_37	-1	known	in_frame_del	c.1369_1367	p.CN456in_frame_delY	1.000:1.000:1.000	pfam_Notch_dom,superfamily_Notch_dom,smart_Notch_dom,pfscan_Notch_dom	pfam_DMAP1-bd,pfam_Notch_dom,pfam_DUF3184,superfamily_Notch_dom,smart_Notch_dom,pfscan_EF_hand_dom,pfscan_Notch_dom	-	no_errors	GNPTAB	HGNC	ENSG00000111670	tier1			73	0	0.00	63	29	31.52	166	0	0.00	119	48	28.74
NEBL	0	genome.wustl.edu	37	10	21129758	21129758	+	Silent	SNP	C	C	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	10	21129758	21129758	C	T	SNP	NEBL	ENST00000377122	human	ensembl	74_37	-1	known	silent	c.1248	p.L416	1.000	smart_Nebulin_35r-motif	pfam_Nebulin_35r-motif,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,smart_Nebulin_35r-motif,smart_SH3_domain,pfscan_Nebulin_35r-motif,pfscan_SH3_domain,prints_SH3_domain	-	no_errors	NEBL	HGNC	ENSG00000078114	tier1	-	-	22	0	0.00	3	14	82.35	51	0	0.00	1	34	97.14
NPTX2	0	genome.wustl.edu	37	7	98249052	98249052	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	7	98249052	98249052	G	A	SNP	NPTX2	ENST00000265634	human	ensembl	74_37	+1	known	missense	c.524	p.R175H	0.689	NULL	pfam_Pentaxin,superfamily_ConA-like_lec_gl_sf,smart_Pentaxin,prints_Pentaxin	-	no_errors	NPTX2	HGNC	ENSG00000106236	tier1	-	-	45	0	0.00	33	23	40.35	11	0	0.00	5	5	50.00
SSH1	0	genome.wustl.edu	37	12	109182324	109182324	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	12	109182324	109182324	C	T	SNP	SSH1	ENST00000326495	human	ensembl	74_37	-1	known	missense	c.2590	p.A864T	0.000	NULL	pfam_Dual-sp_phosphatase_cat-dom,pfam_DEK_C,smart_Dual-sp_phosphatase_subgr_cat,pfscan_Tyr/Dual-sp_Pase,pfscan_Dual-sp_phosphatase_subgr_cat	-	no_errors	SSH1	HGNC	ENSG00000084112	tier1	-	-	28	0	0.00	8	10	55.56	12	0	0.00	4	6	60.00
ZNF385B	0	genome.wustl.edu	37	2	180348073	180348073	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	2	180348073	180348073	G	T	SNP	ZNF385B	ENST00000410066	human	ensembl	74_37	-1	known	missense	c.596	p.P199H	1.000	NULL	pfam_Znf_C2H2_jaz,smart_Znf_U1,smart_Znf_C2H2-like	-	no_errors	ZNF385B	HGNC	ENSG00000144331	tier1	-	-	101	0	0.00	145	20	12.12	137	0	0.00	124	11	8.15
ANP32BP1	0	genome.wustl.edu	37	15	75614886	75614886	+	R	SNP	C	C	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	15	75614886	75614886	C	T	SNP	ANP32BP1	ENST00000564205	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.282	-	-	-	no_errors	ANP32BP1	HGNC	ENSG00000259790	tier1	-	-	74	0	0.00	76	44	36.67	10	0	0.00	4	1	20.00
SYT8	0	genome.wustl.edu	37	11	1856623	1856623	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	11	1856623	1856623	G	A	SNP	SYT8	ENST00000424556	human	ensembl	74_37	+1	known	missense	c.209	p.G70E	0.140	NULL	NULL	-	no_errors	SYT8	HGNC	ENSG00000149043	tier1	-	-	36	0	0.00	37	24	39.34	7	0	0.00	5	0	0.00
CAC1H	0	genome.wustl.edu	37	16	1270617	1270617	+	Missense_Mutation	SNP	A	A	T			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	16	1270617	1270617	A	T	SNP	CAC1H	ENST00000348261	human	ensembl	74_37	+1	known	missense	c.6685	p.R2229W	0.989	NULL	pfam_Ion_trans_dom,pfam_PKD1_2_channel,prints_VDCC_T_a1su,prints_PKD_2	-	no_errors	CAC1H	HGNC	ENSG00000196557	tier1	-	-	10	0	0.00	14	17	54.84	3	0	0.00	1	0	0.00
CD209	0	genome.wustl.edu	37	19	7810620	7810620	+	Missense_Mutation	SNP	C	C	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	19	7810620	7810620	C	A	SNP	CD209	ENST00000315599	human	ensembl	74_37	-1	known	missense	c.532	p.A178S	0.002	NULL	pfam_C-type_lectin,superfamily_C-type_lectin_fold,smart_C-type_lectin,pfscan_C-type_lectin,prints_AntifreezeII	-	no_errors	CD209	HGNC	ENSG00000090659	tier1	-	-	152	0	0.00	117	76	39.38	0	0	0.00	0	0	0.00
ENSG00000207207	0	genome.wustl.edu	37	2	85661741	85661741	+	R	DEL	A	A	-			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	2	85661741	85661741	A	-	DEL	ENSG00000207207	ENST00000384478	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.006	-	-	-	no_errors	Y_R	RFAM	ENSG00000207207	tier1			14	0	0.00	23	4	14.81	1	0	0.00	5	0	0.00
FAM230B	0	genome.wustl.edu	37	22	21537782	21537782	+	R	SNP	G	G	A			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	22	21537782	21537782	G	A	SNP	FAM230B	ENST00000451257	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	FAM230B	HGNC	ENSG00000215498	tier1	rs12172393	-	30	0	0.00	43	8	15.69	0	0	0.00	1	0	0.00
HOXD8	0	genome.wustl.edu	37	2	176995302	176995303	+	In_Frame_Ins	INS	-	-	CGCACC			TCGA-X6-A7WD-01A-21D-A351-09	TCGA-X6-A7WD-10A-01D-A351-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6a327d8b-23f5-46e7-91a9-33e4fd0bf8d4	91308f69-8b3e-4ceb-9754-926945ab8da8	2	176995302	176995303	-	CGCACC	INS	HOXD8	ENST00000313173	human	ensembl	74_37	+1	known	in_frame_ins	c.208_209	p.74in_frame_insPH	0.993:1.000	NULL	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,prints_Homeobox_metazoa,pfscan_Homeobox_dom	-	no_errors	HOXD8	HGNC	ENSG00000175879	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00