Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
NT5C3AP1	0	genome.wustl.edu	37	4	118496711	118496711	+	R	SNP	T	T	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	4	118496711	118496711	T	A	SNP	NT5C3AP1	ENST00000441170	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.925	-	-	-	no_errors	NT5C3AP1	HGNC	ENSG00000213492	tier1	-	-	57	0	0.00	31	16	34.04	51	0	0.00	46	52	53.06
SF3A3	0	genome.wustl.edu	37	1	38442606	38442606	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	1	38442606	38442606	C	T	SNP	SF3A3	ENST00000373019	human	ensembl	74_37	-1	known	missense	c.955	p.D319N	1.000	NULL	pfam_DUF3449,pfam_SF3a60_bindingd,pfscan_Znf_C2H2_matrin	-	no_errors	SF3A3	HGNC	ENSG00000183431	tier1	-	-	65	0	0.00	41	31	43.06	116	0	0.00	45	45	49.45
MUC5B	0	genome.wustl.edu	37	11	1267347	1267347	+	Silent	SNP	C	C	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	11	1267347	1267347	C	A	SNP	MUC5B	ENST00000447027	human	ensembl	74_37	+1	known	silent	c.9246	p.T3082	0.031	NULL	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC5B	HGNC	ENSG00000117983	tier1	-	-	75	0	0.00	18	5	21.74	40	0	0.00	18	6	24.00
BRINP3	0	genome.wustl.edu	37	1	190067251	190067251	+	Missense_Mutation	SNP	T	T	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	1	190067251	190067251	T	A	SNP	BRINP3	ENST00000367462	human	ensembl	74_37	-1	known	missense	c.2198	p.K733M	1.000	NULL	pfam_MACPF,smart_MACPF	-	no_errors	BRINP3	HGNC	ENSG00000162670	tier1	-	-	41	0	0.00	0	35	100.00	70	1	1.39	11	93	89.42
UGT3A1	0	genome.wustl.edu	37	5	35965701	35965701	+	Silent	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	5	35965701	35965701	G	A	SNP	UGT3A1	ENST00000274278	human	ensembl	74_37	-1	known	silent	c.630	p.F210	0.001	pfam_UDP_glucos_trans	pfam_UDP_glucos_trans,pfam_Glyco_trans_28_C	-	no_errors	UGT3A1	HGNC	ENSG00000145626	tier1	-	-	57	0	0.00	30	47	61.04	162	1	0.61	39	62	61.39
CCDC33	0	genome.wustl.edu	37	15	74564053	74564053	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	15	74564053	74564053	C	T	SNP	CCDC33	ENST00000321288	human	ensembl	74_37	+1	known	missense	c.1165	p.R389W	0.812	NULL	pfam_C2_dom,superfamily_C2_dom	-	no_errors	CCDC33	HGNC	ENSG00000140481	tier1	rs201603982	-	71	0	0.00	51	17	25.00	171	0	0.00	119	21	15.00
ZBTB41	0	genome.wustl.edu	37	1	197127605	197127605	+	R	SNP	T	T	C			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	1	197127605	197127605	T	C	SNP	ZBTB41	ENST00000467322	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.003	-	-	-	no_errors	ZBTB41	HGNC	ENSG00000177888	tier1	rs115447450	GMAF=0.0005	32	0	0.00	9	58	86.57	89	0	0.00	10	154	93.90
DCC	0	genome.wustl.edu	37	18	50985606	50985606	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	18	50985606	50985606	C	T	SNP	DCC	ENST00000442544	human	ensembl	74_37	+1	known	missense	c.3397	p.R1133W	1.000	pfam_Neogenin_C	pfam_Neogenin_C,pfam_Fibronectin_type3,pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	DCC	HGNC	ENSG00000187323	tier1	-	-	52	0	0.00	11	19	63.33	121	0	0.00	23	95	79.83
RSPH1	0	genome.wustl.edu	37	21	43905899	43905899	+	Silent	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	21	43905899	43905899	G	A	SNP	RSPH1	ENST00000291536	human	ensembl	74_37	-1	known	silent	c.381	p.T127	1.000	pfam_MORN,smart_MORN	pfam_MORN,smart_MORN	-	no_errors	RSPH1	HGNC	ENSG00000160188	tier1	-	-	53	0	0.00	33	5	13.16	194	0	0.00	95	38	28.57
KRT77	0	genome.wustl.edu	37	12	53086400	53086400	+	Missense_Mutation	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	12	53086400	53086400	G	A	SNP	KRT77	ENST00000341809	human	ensembl	74_37	-1	known	missense	c.1232	p.S411L	0.560	pfam_IF	pfam_IF,superfamily_Prefoldin,prints_Keratin_II	-	no_errors	KRT77	HGNC	ENSG00000189182	tier1	rs201690097	GMAF=0.0005	39	0	0.00	11	13	54.17	74	0	0.00	35	21	37.50
DH8	0	genome.wustl.edu	37	6	38816506	38816506	+	Missense_Mutation	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	6	38816506	38816506	G	A	SNP	DH8	ENST00000359357	human	ensembl	74_37	+1	known	missense	c.4477	p.V1493I	0.001	pfam_Dynein_heavy_dom-2	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DH8	HGNC	ENSG00000124721	tier1	-	-	29	0	0.00	46	43	44.33	139	0	0.00	105	54	33.96
LRRTM4	0	genome.wustl.edu	37	2	77746658	77746658	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	2	77746658	77746658	C	T	SNP	LRRTM4	ENST00000409911	human	ensembl	74_37	-1	known	missense	c.340	p.E114K	1.000	smart_Leu-rich_rpt_typical-subtyp	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRTM4	HGNC	ENSG00000176204	tier1	-	-	33	0	0.00	9	41	82.00	126	0	0.00	16	61	79.22
HS3ST6	0	genome.wustl.edu	37	16	1961876	1961876	+	Silent	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	16	1961876	1961876	G	A	SNP	HS3ST6	ENST00000293937	human	ensembl	74_37	-1	known	silent	c.744	p.S248	0.988	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	-	no_errors	HS3ST6	HGNC	ENSG00000162040	tier1	-	-	131	1	0.76	59	45	43.27	31	0	0.00	18	3	13.64
PKHD1	0	genome.wustl.edu	37	6	51619707	51619707	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	6	51619707	51619707	C	T	SNP	PKHD1	ENST00000371117	human	ensembl	74_37	-1	known	missense	c.8672	p.R2891H	0.009	NULL	pfam_IPT,pfam_G8_domain,superfamily_Ig_E-set,superfamily_Pectin_lyase_fold/virulence,smart_IPT,smart_PbH1	-	no_errors	PKHD1	HGNC	ENSG00000170927	tier1	-	-	8	0	0.00	9	21	70.00	109	0	0.00	46	28	37.84
GPR50	0	genome.wustl.edu	37	X	150349083	150349083	+	Missense_Mutation	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	X	150349083	150349083	G	A	SNP	GPR50	ENST00000218316	human	ensembl	74_37	+1	known	missense	c.1028	p.R343H	0.041	prints_Mel_rcpt_1X	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_Mel_rcpt_1X,prints_GPCR_Rhodpsn,prints_Melatonin_rcpt,prints_NPY_rcpt	-	no_errors	GPR50	HGNC	ENSG00000102195	tier1	-	-	20	0	0.00	0	33	100.00	28	0	0.00	12	28	70.00
LOC100996291	0	genome.wustl.edu	37	17	76267801	76267801	+	R	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	17	76267801	76267801	C	T	SNP	LOC100996291	ENST00000374945	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	RP11-219G17.4	Clone_based_vega_gene	ENSG00000204277	tier1	-	-	32	0	0.00	19	7	26.92	175	0	0.00	54	31	36.47
ENSG00000204398	0	genome.wustl.edu	37	13	112240744	112240744	+	R	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	13	112240744	112240744	C	T	SNP	ENSG00000204398	ENST00000607406	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-65D24.2	Clone_based_vega_gene	ENSG00000204398	tier1	-	-	44	0	0.00	35	12	25.53	68	0	0.00	75	26	25.74
SCN10A	0	genome.wustl.edu	37	3	38798178	38798178	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	3	38798178	38798178	C	T	SNP	SCN10A	ENST00000449082	human	ensembl	74_37	-1	known	missense	c.1277	p.R426Q	0.950	NULL	pfam_Ion_trans_dom,pfam_Na_trans_assoc,pfam_PKD1_2_channel,prints_Na_channel_asu,prints_PKD_2	-	no_errors	SCN10A	HGNC	ENSG00000185313	tier1	rs143033805	GMAF=0.0005	34	0	0.00	31	15	32.61	137	0	0.00	76	33	30.28
DUSP13	0	genome.wustl.edu	37	10	76854531	76854531	+	Missense_Mutation	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	10	76854531	76854531	G	A	SNP	DUSP13	ENST00000491677	human	ensembl	74_37	-1	known	missense	c.887	p.T296M	0.897	pfam_Dual-sp_phosphatase_cat-dom,pfam_Tyr_Pase_rcpt/non-rcpt,smart_Dual-sp_phosphatase_subgr_cat,pfscan_Tyr/Dual-sp_Pase,pfscan_Dual-sp_phosphatase_subgr_cat	pfam_Dual-sp_phosphatase_cat-dom,pfam_Tyr_Pase_rcpt/non-rcpt,smart_Dual-sp_phosphatase_subgr_cat,pfscan_Tyr/Dual-sp_Pase,pfscan_Dual-sp_phosphatase_subgr_cat,prints_Atypical_DUSP,prints_Atypical_DUSP_famA	-	no_errors	DUSP13	HGNC	ENSG00000079393	tier1	rs150329504	-	49	0	0.00	11	14	56.00	58	0	0.00	31	30	49.18
AKAP6	0	genome.wustl.edu	37	14	33014696	33014696	+	Silent	SNP	T	T	C			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	14	33014696	33014696	T	C	SNP	AKAP6	ENST00000280979	human	ensembl	74_37	+1	known	silent	c.837	p.A279	0.977	NULL	smart_Spectrin/alpha-actinin	-	no_errors	AKAP6	HGNC	ENSG00000151320	tier1	-	-	18	0	0.00	17	9	34.62	164	0	0.00	90	34	27.42
ZNF823	0	genome.wustl.edu	37	19	11832715	11832715	+	Missense_Mutation	SNP	T	T	C			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	19	11832715	11832715	T	C	SNP	ZNF823	ENST00000341191	human	ensembl	74_37	-1	known	missense	c.1634	p.H545R	0.952	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF823	HGNC	ENSG00000197933	tier1	-	-	82	0	0.00	27	41	60.29	60	0	0.00	14	10	41.67
LOC285556	0	genome.wustl.edu	37	4	100574097	100574097	+	Missense_Mutation	SNP	T	T	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	4	100574097	100574097	T	A	SNP	LOC285556	ENST00000511828	human	ensembl	74_37	-1	putative	missense	c.1709	p.N570I	0.002	NULL	NULL	-	no_errors	RP11-766F14.2	Clone_based_vega_gene	ENSG00000248713	tier1	-	-	60	0	0.00	27	26	49.06	54	0	0.00	59	54	47.79
ENSG00000244227	0	genome.wustl.edu	37	3	167621200	167621200	+	R	SNP	A	A	G			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	3	167621200	167621200	A	G	SNP	ENSG00000244227	ENST00000459923	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.053	-	-	-	no_errors	RP11-298O21.5	Clone_based_vega_gene	ENSG00000244227	tier1	-	-	40	0	0.00	7	39	84.78	137	0	0.00	17	77	81.91
MARCH11	0	genome.wustl.edu	37	5	16067845	16067845	+	Missense_Mutation	SNP	A	A	G			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	5	16067845	16067845	A	G	SNP	MARCH11	ENST00000332432	human	ensembl	74_37	-1	known	missense	c.944	p.V315A	0.999	NULL	pfam_Znf_C3HC4_RING-type,smart_Znf_RING-CH	-	no_errors	MARCH11	HGNC	ENSG00000183654	tier1	-	-	29	0	0.00	32	15	31.91	155	0	0.00	65	32	32.99
LOC401286	0	genome.wustl.edu	37	6	168069993	168069993	+	R	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	6	168069993	168069993	G	A	SNP	LOC401286	ENST00000609107	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-351J23.2	Clone_based_vega_gene	ENSG00000272549	tier1	-	-	82	0	0.00	43	12	21.82	118	0	0.00	50	18	26.47
OTP	0	genome.wustl.edu	37	5	76932753	76932753	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	5	76932753	76932753	C	T	SNP	OTP	ENST00000306422	human	ensembl	74_37	-1	known	missense	c.340	p.A114T	1.000	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom	pfam_Homeobox_dom,pfam_OAR_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,prints_HTH_motif,pfscan_OAR_dom,pfscan_Homeobox_dom	-	no_errors	OTP	HGNC	ENSG00000171540	tier1	-	-	82	0	0.00	26	18	40.91	43	0	0.00	37	8	17.78
SLCO1B3	0	genome.wustl.edu	37	12	21028281	21028281	+	Silent	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	12	21028281	21028281	G	A	SNP	SLCO1B3	ENST00000553473	human	ensembl	74_37	+1	known	silent	c.840	p.P280	0.016	pfam_OA_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	pfam_OA_transporter,pfam_MFS,pfam_Kazal_dom,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	-	no_errors	SLCO1B3	HGNC	ENSG00000111700	tier1	-	-	74	0	0.00	51	17	25.00	66	0	0.00	18	5	21.74
EPAS1	0	genome.wustl.edu	37	2	46605046	46605046	+	Silent	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	2	46605046	46605046	C	T	SNP	EPAS1	ENST00000263734	human	ensembl	74_37	+1	known	silent	c.1263	p.F421	0.731	NULL	pfam_PAS_fold_3,pfam_HIF-1_TAD_C,pfam_HIF_alpha_subunit,pfam_PAS_fold,superfamily_PAS,superfamily_bHLH_dom,smart_bHLH_dom,smart_PAS,smart_PAC,prints_Nuc_translocat,pfscan_PAS,pfscan_bHLH_dom,tigrfam_PAS	-	no_errors	EPAS1	HGNC	ENSG00000116016	tier1	-	-	66	0	0.00	14	8	36.36	50	0	0.00	41	33	44.59
DDX18	0	genome.wustl.edu	37	2	118582579	118582579	+	Nonsense_Mutation	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	2	118582579	118582579	C	T	SNP	DDX18	ENST00000263239	human	ensembl	74_37	+1	known	nonsense	c.1270	p.R424*	1.000	superfamily_P-loop_NTPase,pfscan_Helicase_C	pfam_D/R_helicase_DEAD/DEAH_N,pfam_Helicase_C,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	DDX18	HGNC	ENSG00000088205	tier1	-	-	30	0	0.00	23	4	14.81	41	0	0.00	25	3	10.71
KLHL1	0	genome.wustl.edu	37	13	70681572	70681572	+	Missense_Mutation	SNP	G	G	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	13	70681572	70681572	G	T	SNP	KLHL1	ENST00000377844	human	ensembl	74_37	-1	known	missense	c.260	p.S87Y	1.000	NULL	pfam_Kelch_1,pfam_Kelch_2,pfam_BACK,pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pfscan_BTB/POZ-like	-	no_errors	KLHL1	HGNC	ENSG00000150361	tier1	-	-	68	0	0.00	46	11	19.30	61	0	0.00	103	13	11.21
DACH2	0	genome.wustl.edu	37	X	85404005	85404005	+	Missense_Mutation	SNP	G	G	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	X	85404005	85404005	G	T	SNP	DACH2	ENST00000373125	human	ensembl	74_37	+1	known	missense	c.381	p.Q127H	1.000	pfam_Transform_Ski,superfamily_D-bd_dom_put	pfam_Transform_Ski,superfamily_D-bd_dom_put	-	no_errors	DACH2	HGNC	ENSG00000126733	tier1	-	-	67	0	0.00	30	19	38.78	64	0	0.00	19	13	40.62
CAC1H	0	genome.wustl.edu	37	16	1250294	1250294	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	16	1250294	1250294	C	T	SNP	CAC1H	ENST00000348261	human	ensembl	74_37	+1	known	missense	c.842	p.T281M	0.341	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_PKD1_2_channel,prints_VDCC_T_a1su,prints_PKD_2	-	no_errors	CAC1H	HGNC	ENSG00000196557	tier1	-	-	122	0	0.00	65	23	26.14	182	0	0.00	86	23	21.10
ATG5	0	genome.wustl.edu	37	6	106696116	106696116	+	Missense_Mutation	SNP	C	C	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	6	106696116	106696116	C	A	SNP	ATG5	ENST00000343245	human	ensembl	74_37	-1	known	missense	c.482	p.R161I	1.000	pfam_Atg5	pfam_Atg5	-	no_errors	ATG5	HGNC	ENSG00000057663	tier1	-	-	93	0	0.00	110	71	39.23	167	0	0.00	78	77	49.68
ADARB2	0	genome.wustl.edu	37	10	1313200	1313200	+	Missense_Mutation	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	10	1313200	1313200	G	A	SNP	ADARB2	ENST00000381312	human	ensembl	74_37	-1	known	missense	c.1142	p.T381M	0.034	smart_A_deamin	pfam_A_deamin,pfam_dsR-bd_dom,smart_dsR-bd_dom,smart_A_deamin,pfscan_dsR-bd_dom,pfscan_A_deamin	-	no_errors	ADARB2	HGNC	ENSG00000185736	tier1	-	-	45	0	0.00	16	21	56.76	85	0	0.00	68	37	35.24
PRKCG	0	genome.wustl.edu	37	19	54395787	54395787	+	Silent	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	19	54395787	54395787	G	A	SNP	PRKCG	ENST00000540413	human	ensembl	74_37	+1	known	silent	c.711	p.E237	1.000	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pirsf_Protein_kinase_C_a/b/g,pfscan_C2_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_Kinase_C-like_PE/DAG-bd,pfam_C2_dom,pfam_Pkinase_C,superfamily_Kinase-like_dom,superfamily_C2_dom,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_C2_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,pirsf_Protein_kinase_C_a/b/g,prints_DAG/PE-bd,prints_C2_dom,pfscan_C2_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_dom	-	no_errors	PRKCG	HGNC	ENSG00000126583	tier1	-	-	204	0	0.00	79	35	30.70	64	0	0.00	33	11	25.00
AP3D1	0	genome.wustl.edu	37	19	2129394	2129394	+	Silent	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	19	2129394	2129394	G	A	SNP	AP3D1	ENST00000355272	human	ensembl	74_37	-1	known	silent	c.655	p.L219	1.000	pfam_Clathrin/coatomer_adapt-like_N,superfamily_ARM-type_fold,pirsf_AP3_complex_dsu	pfam_BLV_receptor,pfam_Clathrin/coatomer_adapt-like_N,superfamily_ARM-type_fold,pirsf_AP3_complex_dsu	-	no_errors	AP3D1	HGNC	ENSG00000065000	tier1	rs199695826	-	78	0	0.00	22	19	46.34	117	0	0.00	58	30	33.71
HECW1	0	genome.wustl.edu	37	7	43351444	43351444	+	Missense_Mutation	SNP	A	A	G			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	7	43351444	43351444	A	G	SNP	HECW1	ENST00000395891	human	ensembl	74_37	+1	known	missense	c.110	p.E37G	1.000	NULL	pfam_HECT,pfam_WW_dom,pfam_C2_dom,superfamily_HECT,superfamily_WW_dom,superfamily_C2_dom,smart_C2_dom,smart_WW_dom,smart_HECT,pfscan_HECT,pfscan_C2_dom,pfscan_WW_dom	-	no_errors	HECW1	HGNC	ENSG00000002746	tier1	-	-	27	0	0.00	17	14	45.16	130	0	0.00	45	33	42.31
BVES-AS1	0	genome.wustl.edu	37	6	105614546	105614546	+	R	SNP	T	T	G			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	6	105614546	105614546	T	G	SNP	BVES-AS1	ENST00000369122	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	BVES-AS1	HGNC	ENSG00000203808	tier1	-	-	66	0	0.00	79	11	12.22	220	0	0.00	135	27	16.56
GSE1	0	genome.wustl.edu	37	16	85694912	85694912	+	Nonsense_Mutation	SNP	G	G	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	16	85694912	85694912	G	T	SNP	GSE1	ENST00000253458	human	ensembl	74_37	+1	known	nonsense	c.1801	p.E601*	0.947	NULL	pfam_GSE-like	-	no_errors	GSE1	HGNC	ENSG00000131149	tier1	-	-	58	0	0.00	32	14	30.43	19	0	0.00	10	4	28.57
TP53	0	genome.wustl.edu	37	17	7574034	7574034	+	Splice_Site	SNP	C	C	G			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	17	7574034	7574034	C	G	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	splice_site	c.994-1	e9-1	1.000	-	-	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	43	0	0.00	6	30	83.33	12	0	0.00	13	84	86.60
SLC30A8	0	genome.wustl.edu	37	8	118147610	118147610	+	Missense_Mutation	SNP	C	C	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	8	118147610	118147610	C	A	SNP	SLC30A8	ENST00000456015	human	ensembl	74_37	+1	known	missense	c.44	p.A15D	1.000	NULL	pfam_Cation_efflux,tigrfam_Cation_efflux	-	no_errors	SLC30A8	HGNC	ENSG00000164756	tier1	-	-	26	0	0.00	72	13	15.29	223	0	0.00	110	22	16.67
CTTN	0	genome.wustl.edu	37	11	70281823	70281823	+	Missense_Mutation	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	11	70281823	70281823	G	A	SNP	CTTN	ENST00000538675	human	ensembl	74_37	+1	known	missense	c.914	p.C305Y	0.000	NULL	pfam_SH3_domain,superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain	-	no_errors	CTTN	HGNC	ENSG00000085733	tier1	-	-	105	0	0.00	56	33	37.08	82	0	0.00	70	37	34.58
ARHGAP23P1	0	genome.wustl.edu	37	16	33739328	33739328	+	R	SNP	C	C	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	16	33739328	33739328	C	A	SNP	ARHGAP23P1	ENST00000567025	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.998	-	-	-	no_errors	ARHGAP23P1	HGNC	ENSG00000260781	tier1	-	-	108	0	0.00	62	11	15.07	25	0	0.00	13	4	23.53
MTFMT	0	genome.wustl.edu	37	15	65295423	65295423	+	Missense_Mutation	SNP	C	C	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	15	65295423	65295423	C	A	SNP	MTFMT	ENST00000220058	human	ensembl	74_37	-1	known	missense	c.1147	p.A383S	1.000	NULL	pfam_Formyl_transf_N,pfam_Formyl_trans_C,superfamily_Formyl_transf_N,superfamily_Formyl_transferase_C-like,tigrfam_Fmt	-	no_errors	MTFMT	HGNC	ENSG00000103707	tier1	-	-	49	0	0.00	33	9	21.43	69	0	0.00	55	10	15.38
GRIK2	0	genome.wustl.edu	37	6	102250236	102250236	+	Missense_Mutation	SNP	A	A	G			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	6	102250236	102250236	A	G	SNP	GRIK2	ENST00000421544	human	ensembl	74_37	+1	known	missense	c.1126	p.T376A	1.000	pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I	pfam_ANF_lig-bd_rcpt,pfam_Iontro_glu_rcpt,pfam_Glu_rcpt_Glu/Gly-bd,pfam_SBP_bac_3,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIK2	HGNC	ENSG00000164418	tier1	-	-	39	0	0.00	38	34	47.22	84	0	0.00	74	43	36.75
TNFRSF21	0	genome.wustl.edu	37	6	47202418	47202418	+	Missense_Mutation	SNP	A	A	G			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	6	47202418	47202418	A	G	SNP	TNFRSF21	ENST00000296861	human	ensembl	74_37	-1	known	missense	c.1726	p.F576L	1.000	NULL	pfam_Death_domain,superfamily_DEATH-like_dom,smart_TNFR/NGFR_Cys_rich_reg,smart_Death_domain,pfscan_Death_domain,pfscan_TNFR/NGFR_Cys_rich_reg,prints_TNFR_21	-	no_errors	TNFRSF21	HGNC	ENSG00000146072	tier1	-	-	36	0	0.00	58	13	18.31	113	0	0.00	96	11	10.28
OR52R1	0	genome.wustl.edu	37	11	4825681	4825681	+	Frame_Shift_Del	DEL	T	T	-			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	T	T	T	-	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	11	4825681	4825681	T	-	DEL	OR52R1	ENST00000380382	human	ensembl	74_37	-1	known	frame_shift_del	c.167	p.N56fs	0.000	NULL	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR52R1	HGNC	ENSG00000176937	tier1			37	0	0.00	41	7	14.58	111	0	0.00	50	38	43.18
KIAA0430	0	genome.wustl.edu	37	16	15696480	15696481	+	Frame_Shift_Ins	INS	-	-	AGGAAAGAAGGAGGGAGGCAGAG			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	-	-	-	AGGAAAGAAGGAGGGAGGCAGAG	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	16	15696480	15696481	-	AGGAAAGAAGGAGGGAGGCAGAG	INS	KIAA0430	ENST00000344181	human	ensembl	74_37	-1	known	frame_shift_ins	c.3339_3338	p.P1114fs	0.000:0.000	NULL	pfam_Limkain_b1_cons_dom,pfam_NYN_limkain-b1,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	KIAA0430	HGNC	ENSG00000166783	tier1			23	0	0.00	15	3	16.67	23	0	0.00	15	3	16.67
ITGA6	0	genome.wustl.edu	37	2	173349540	173349540	+	Missense_Mutation	SNP	A	A	G			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	2	173349540	173349540	A	G	SNP	ITGA6	ENST00000264106	human	ensembl	74_37	+1	known	missense	c.1697	p.E566G	0.998	pfam_Integrin_alpha-2	pfam_Integrin_alpha-2,pfam_FG-GAP,smart_Int_alpha_beta-p,prints_Integrin_alpha	-	no_errors	ITGA6	HGNC	ENSG00000091409	tier1	-	-	31	0	0.00	4	13	76.47	67	0	0.00	4	33	84.62
KCNC4	0	genome.wustl.edu	37	1	110768794	110768794	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	1	110768794	110768794	C	T	SNP	KCNC4	ENST00000369787	human	ensembl	74_37	+1	known	missense	c.1813	p.R605W	1.000	NULL	pfam_Ion_trans_dom,pfam_T1-type_BTB,pfam_K_chnl_volt-dep_Kv3_ID,pfam_2pore_dom_K_chnl_dom,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,prints_K_chnl,prints_K_chnl_volt-dep_Kv3,prints_K_chnl_volt-dep_Kv3.4,prints_K_chnl_volt-dep_Kv,prints_K_chnl_volt-dep_Kv9	-	no_errors	KCNC4	HGNC	ENSG00000116396	tier1	rs200184574	-	140	0	0.00	14	39	73.58	90	0	0.00	5	35	87.50
OR10Q1	0	genome.wustl.edu	37	11	57996225	57996225	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	11	57996225	57996225	C	T	SNP	OR10Q1	ENST00000316770	human	ensembl	74_37	-1	known	missense	c.123	p.M41I	0.003	prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR10Q1	HGNC	ENSG00000180475	tier1	-	-	41	0	0.00	5	21	80.77	62	0	0.00	7	28	80.00
MTMR12	0	genome.wustl.edu	37	5	32268807	32268807	+	Missense_Mutation	SNP	C	C	G			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	5	32268807	32268807	C	G	SNP	MTMR12	ENST00000382142	human	ensembl	74_37	-1	known	missense	c.583	p.V195L	0.996	NULL	pfam_Myotubularin_assoc	-	no_errors	MTMR12	HGNC	ENSG00000150712	tier1	-	-	40	0	0.00	47	5	9.62	178	0	0.00	106	8	7.02
MACF1	0	genome.wustl.edu	37	1	39752957	39752957	+	Splice_Site	SNP	G	G	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	1	39752957	39752957	G	T	SNP	MACF1	ENST00000317713	human	ensembl	74_37	+1	known	splice_site	c.1524-1	e14-1	1.000	-	-	-	no_errors	MACF1	HGNC	ENSG00000127603	tier1	-	-	44	0	0.00	30	30	50.00	118	2	1.67	68	45	39.47
ARHGAP23	0	genome.wustl.edu	37	17	36638789	36638789	+	Missense_Mutation	SNP	G	G	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	17	36638789	36638789	G	T	SNP	ARHGAP23	ENST00000431231	human	ensembl	74_37	+1	known	missense	c.2777	p.C926F	1.000	pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom	pfam_RhoGAP_dom,pfam_PDZ,pfam_Pleckstrin_homology,superfamily_Rho_GTPase_activation_prot,superfamily_PDZ,smart_PDZ,smart_Pleckstrin_homology,smart_RhoGAP_dom,pfscan_PDZ,pfscan_Pleckstrin_homology,pfscan_RhoGAP_dom	-	no_errors	ARHGAP23	HGNC	ENSG00000225485	tier1	-	-	101	0	0.00	39	4	9.30	8	0	0.00	5	0	0.00
ENSG00000258973	0	genome.wustl.edu	37	14	24802126	24802126	+	Missense_Mutation	SNP	C	C	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	14	24802126	24802126	C	T	SNP	ENSG00000258973	ENST00000555591	human	ensembl	74_37	-1	putative	missense	c.427	p.G143R	0.999	NULL	NULL	-	no_errors	RP11-934B9.3	Clone_based_vega_gene	ENSG00000258973	tier1	-	-	35	0	0.00	29	4	12.12	19	0	0.00	5	0	0.00
ENSG00000266008	0	genome.wustl.edu	37	19	21880281	21880281	+	R	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	19	21880281	21880281	G	A	SNP	ENSG00000266008	ENST00000579236	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.163	-	-	-	no_errors	AC092364.4	Clone_based_ensembl_gene	ENSG00000266008	tier1	-	-	22	0	0.00	6	5	45.45	31	0	0.00	2	1	33.33
DUSP9	0	genome.wustl.edu	37	X	152915639	152915639	+	Missense_Mutation	SNP	G	G	T			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	X	152915639	152915639	G	T	SNP	DUSP9	ENST00000342782	human	ensembl	74_37	+1	known	missense	c.1034	p.R345L	0.993	pirsf_MKP,pfscan_Dual-sp_phosphatase_subgr_cat	pfam_Dual-sp_phosphatase_cat-dom,pfam_Rhodanese-like_dom,superfamily_Rhodanese-like_dom,smart_Rhodanese-like_dom,smart_Dual-sp_phosphatase_subgr_cat,pirsf_MKP,pfscan_Rhodanese-like_dom,pfscan_Tyr/Dual-sp_Pase,pfscan_Dual-sp_phosphatase_subgr_cat,prints_MKP	-	no_errors	DUSP9	HGNC	ENSG00000130829	tier1	-	-	38	0	0.00	40	5	11.11	2	0	0.00	2	0	0.00
NBPF11	0	genome.wustl.edu	37	1	146055349	146055349	+	Missense_Mutation	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	1	146055349	146055349	G	A	SNP	NBPF11	ENST00000604938	human	ensembl	74_37	-1	known	missense	c.274	p.L92F	0.060	NULL	pfam_NBPF_dom,superfamily_Secretoglobin	-	no_errors	NBPF11	HGNC	ENSG00000152042	tier1	rs200002878	-	10	0	0.00	13	11	45.83	0	0	0.00	0	0	0.00
NRXN1	0	genome.wustl.edu	37	2	50147836	50147847	+	R	DEL	GTGTGTGTGTGT	GTGTGTGTGTGT	-			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	GTGTGTGTGTGT	GTGTGTGTGTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	2	50147836	50147847	GTGTGTGTGTGT	-	DEL	NRXN1	ENST00000484192	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.001:0.005:0.106:0.113:0.127:0.107:0.109:0.093:0.096:0.025:0.055	-	-	-	no_errors	NRXN1	HGNC	ENSG00000179915	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
POTEF	0	genome.wustl.edu	37	2	130832537	130832537	+	Silent	SNP	G	G	A			TCGA-SG-A6Z4-01A-22D-A33E-09	TCGA-SG-A6Z4-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	7f4df9e0-c36b-46fd-b7f3-4912fcb9fc49	eb6b6f4d-e3e1-4475-b6be-0e23e379f2a5	2	130832537	130832537	G	A	SNP	POTEF	ENST00000357462	human	ensembl	74_37	-1	known	silent	c.2508	p.I836	1.000	pfam_Actin-related,smart_Actin-related	pfam_Actin-related,pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_Actin-related,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Actin-related	-	no_errors	POTEF	HGNC	ENSG00000196604	tier1	-	-	63	0	0.00	30	4	11.76	0	0	0.00	0	0	0.00