Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
LRRC8D	0	genome.wustl.edu	37	1	90399271	90399271	+	Missense_Mutation	SNP	A	A	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	1	90399271	90399271	A	G	SNP	LRRC8D	ENST00000337338	human	ensembl	74_37	+1	known	missense	c.644	p.E215G	1.000	NULL	pfam_LRR_protein-8_N,pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRC8D	HGNC	ENSG00000171492	tier1	-	-	37	0	0.00	32	4	11.11						
NEUROD4	0	genome.wustl.edu	37	12	55420485	55420485	+	Nonsense_Mutation	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	12	55420485	55420485	C	T	SNP	NEUROD4	ENST00000242994	human	ensembl	74_37	+1	known	nonsense	c.262	p.R88*	1.000	pfam_bHLH_dom,superfamily_bHLH_dom,pirsf_TF_bHLH_NeuroD,pfscan_bHLH_dom	pfam_Neurogenic_DUF,pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pirsf_TF_bHLH_NeuroD,pfscan_bHLH_dom	-	no_errors	NEUROD4	HGNC	ENSG00000123307	tier1	-	-	34	0	0.00	55	9	14.06						
MIR629	0	genome.wustl.edu	37	15	70371801	70371801	+	R	SNP	A	A	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	15	70371801	70371801	A	G	SNP	MIR629	ENST00000385230	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	MIR629	HGNC	ENSG00000207965	tier1	-	-	39	0	0.00	44	5	10.20						
MYT1L	0	genome.wustl.edu	37	2	1906955	1906955	+	Missense_Mutation	SNP	C	C	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	2	1906955	1906955	C	G	SNP	MYT1L	ENST00000399161	human	ensembl	74_37	-1	known	missense	c.1929	p.K643N	1.000	pfam_Myelin_TF	pfam_Myelin_TF,pfam_Znf_C2HC	-	no_errors	MYT1L	HGNC	ENSG00000186487	tier1	-	-	76	0	0.00	42	8	16.00						
AR	0	genome.wustl.edu	37	X	66765597	66765597	+	Silent	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	X	66765597	66765597	C	T	SNP	AR	ENST00000374690	human	ensembl	74_37	+1	known	silent	c.609	p.S203	0.000	pfam_Andrgn_rcpt	pfam_Andrgn_rcpt,pfam_Znf_hrmn_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Andrgn_rcpt,prints_Znf_hrmn_rcpt	-	no_errors	AR	HGNC	ENSG00000169083	tier1	-	-	121	0	0.00	77	15	16.30						
ZNF808	0	genome.wustl.edu	37	19	53058345	53058345	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	19	53058345	53058345	C	T	SNP	ZNF808	ENST00000359798	human	ensembl	74_37	+1	known	missense	c.2176	p.R726C	0.336	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF808	HGNC	ENSG00000198482	tier1	-	-	130	0	0.00	111	37	25.00						
TAAR2	0	genome.wustl.edu	37	6	132945357	132945357	+	Nonsense_Mutation	SNP	T	T	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	6	132945357	132945357	T	A	SNP	TAAR2	ENST00000367931	human	ensembl	74_37	-1	known	nonsense	c.58	p.K20*	0.003	NULL	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_TAAR_fam	-	no_errors	TAAR2	HGNC	ENSG00000146378	tier1	-	-	17	0	0.00	31	7	18.42						
ENSG00000227082	0	genome.wustl.edu	37	1	121138882	121138882	+	R	SNP	A	A	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	1	121138882	121138882	A	G	SNP	ENSG00000227082	ENST00000417218	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.044	-	-	-	no_errors	AL592494.5	Clone_based_vega_gene	ENSG00000227082	tier1	rs77721662	-	16	0	0.00	5	3	33.33						
HIST3H3	0	genome.wustl.edu	37	1	228612940	228612940	+	Silent	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	1	228612940	228612940	G	A	SNP	HIST3H3	ENST00000366696	human	ensembl	74_37	-1	known	silent	c.87	p.S29	1.000	superfamily_Histone-fold,prints_Histone_H3	pfam_Histone_core_D,superfamily_Histone-fold,smart_Histone_H3,prints_Histone_H3	-	no_errors	HIST3H3	HGNC	ENSG00000168148	tier1	-	-	35	0	0.00	22	5	18.52						
MEF2C	0	genome.wustl.edu	37	5	88025139	88025139	+	Nonsense_Mutation	SNP	G	G	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	5	88025139	88025139	G	T	SNP	MEF2C	ENST00000437473	human	ensembl	74_37	-1	known	nonsense	c.860	p.S287*	1.000	NULL	pfam_TF_MADSbox,pfam_HJURP_C,superfamily_TF_MADSbox,smart_TF_MADSbox,prints_TF_MADSbox,pfscan_TF_MADSbox	-	no_errors	MEF2C	HGNC	ENSG00000081189	tier1	-	-	22	0	0.00	22	14	38.89						
FAM92B	0	genome.wustl.edu	37	16	85141485	85141485	+	Silent	SNP	C	C	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	16	85141485	85141485	C	A	SNP	FAM92B	ENST00000539556	human	ensembl	74_37	-1	known	silent	c.393	p.L131	0.999	pfam_FAM92	pfam_FAM92	-	no_errors	FAM92B	HGNC	ENSG00000153789	tier1	-	-	62	0	0.00	29	7	19.44						
DVL1	0	genome.wustl.edu	37	1	1275822	1275822	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	1	1275822	1275822	G	A	SNP	DVL1	ENST00000378888	human	ensembl	74_37	-1	known	missense	c.667	p.R223W	1.000	superfamily_PDZ	pfam_Dishevelled_C-dom,pfam_DIX,pfam_Dishevelled_protein_dom,pfam_PDZ,pfam_DEP_dom,superfamily_PDZ,smart_DIX,smart_PDZ,smart_DEP_dom,pfscan_DEP_dom,pfscan_DIX,pfscan_PDZ,prints_Dishevelled_fam	-	no_errors	DVL1	HGNC	ENSG00000107404	tier1	-	-	90	0	0.00	57	14	19.72						
TMPRSS11A	0	genome.wustl.edu	37	4	68784778	68784778	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	4	68784778	68784778	G	A	SNP	TMPRSS11A	ENST00000334830	human	ensembl	74_37	-1	known	missense	c.874	p.R292C	0.044	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pirsf_Pept_S1A_HAT/DESC1,pfscan_Peptidase_S1	pfam_Peptidase_S1,pfam_SEA_dom,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pirsf_Pept_S1A_HAT/DESC1,pfscan_Peptidase_S1,prints_Peptidase_S1A	-	no_errors	TMPRSS11A	HGNC	ENSG00000187054	tier1	rs141574463	-	54	0	0.00	57	7	10.94						
MAGEC1	0	genome.wustl.edu	37	X	140994549	140994549	+	Nonsense_Mutation	SNP	C	C	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	X	140994549	140994549	C	A	SNP	MAGEC1	ENST00000285879	human	ensembl	74_37	+1	known	nonsense	c.1359	p.Y453*	0.001	NULL	pfam_MAGE,pfscan_MAGE	-	no_errors	MAGEC1	HGNC	ENSG00000155495	tier1	-	-	117	0	0.00	204	26	11.30						
POLE	0	genome.wustl.edu	37	12	133249233	133249233	+	Missense_Mutation	SNP	T	T	C			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	12	133249233	133249233	T	C	SNP	POLE	ENST00000320574	human	ensembl	74_37	-1	known	missense	c.1666	p.I556V	1.000	smart_D-dir_D_pol_B	pfam_D_pol_e_suA_C,pfam_D-dir_D_pol_B_exonuc,pfam_D-dir_D_pol_B_multi_dom,pfam_3'-5'_exonuclease_PolB-like,superfamily_RNaseH-like_dom,smart_D-dir_D_pol_B	-	no_errors	POLE	HGNC	ENSG00000177084	tier1	-	-	39	0	0.00	20	6	23.08						
IF16	0	genome.wustl.edu	37	9	21217127	21217127	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	9	21217127	21217127	C	T	SNP	IF16	ENST00000380216	human	ensembl	74_37	-1	known	missense	c.178	p.G60R	0.000	pfam_Interferon_alpha/beta/delta,superfamily_4_helix_cytokine-like_core,smart_Interferon_alpha/beta/delta,prints_Interferon_alpha/beta/delta	pfam_Interferon_alpha/beta/delta,superfamily_4_helix_cytokine-like_core,smart_Interferon_alpha/beta/delta,prints_Interferon_alpha/beta/delta	-	no_errors	IF16	HGNC	ENSG00000147885	tier1	-	-	114	0	0.00	105	24	18.60						
ZFYVE28	0	genome.wustl.edu	37	4	2321944	2321944	+	Silent	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	4	2321944	2321944	G	A	SNP	ZFYVE28	ENST00000290974	human	ensembl	74_37	-1	known	silent	c.756	p.D252	1.000	NULL	pfam_Znf_FYVE,superfamily_Znf_FYVE_PHD,smart_Znf_FYVE,pfscan_Znf_FYVE-rel	-	no_errors	ZFYVE28	HGNC	ENSG00000159733	tier1	-	-	158	0	0.00	125	22	14.97						
MYT1	0	genome.wustl.edu	37	20	62839308	62839308	+	Silent	SNP	C	C	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	20	62839308	62839308	C	A	SNP	MYT1	ENST00000536311	human	ensembl	74_37	+1	known	silent	c.759	p.G253	0.000	NULL	pfam_Myelin_TF,pfam_Znf_C2HC	-	no_errors	MYT1	HGNC	ENSG00000196132	tier1	-	-	23	0	0.00	15	3	16.67						
DH8	0	genome.wustl.edu	37	6	38980307	38980307	+	Silent	SNP	G	G	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	6	38980307	38980307	G	T	SNP	DH8	ENST00000359357	human	ensembl	74_37	+1	known	silent	c.12957	p.L4319	1.000	pfam_Dynein_heavy_dom	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DH8	HGNC	ENSG00000124721	tier1	-	-	29	0	0.00	39	9	18.75						
VAV1	0	genome.wustl.edu	37	19	6773005	6773005	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	19	6773005	6773005	C	T	SNP	VAV1	ENST00000602142	human	ensembl	74_37	+1	known	missense	c.187	p.R63C	1.000	pfam_CAMSAP_CH,pfam_CH-domain,superfamily_CH-domain,smart_CH-domain,pfscan_CH-domain	pfam_DH-domain,pfam_SH3_domain,pfam_SH3_2,pfam_CAMSAP_CH,pfam_SH2,pfam_CH-domain,pfam_Prot_Kinase_C-like_PE/DAG-bd,pfam_Pleckstrin_homology,superfamily_DH-domain,superfamily_CH-domain,superfamily_SH3_domain,smart_CH-domain,smart_DH-domain,smart_Pleckstrin_homology,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_SH3_domain,smart_SH2,pfscan_CH-domain,pfscan_Pleckstrin_homology,pfscan_SH2,pfscan_SH3_domain,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_DH-domain,prints_SH3_domain,prints_SH2,prints_SM22_calponin	-	no_errors	VAV1	HGNC	ENSG00000141968	tier1	-	-	98	0	0.00	48	6	11.11						
MTPAP	0	genome.wustl.edu	37	10	30602633	30602633	+	Nonsense_Mutation	SNP	C	C	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	10	30602633	30602633	C	A	SNP	MTPAP	ENST00000358107	human	ensembl	74_37	-1	known	nonsense	c.2044	p.E682*	0.994	NULL	pfam_PAP_assoc	-	no_errors	MTPAP	HGNC	ENSG00000107951	tier1	-	-	67	0	0.00	53	30	36.14						
EPHA6	0	genome.wustl.edu	37	3	97439140	97439140	+	Silent	SNP	A	A	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	3	97439140	97439140	A	G	SNP	EPHA6	ENST00000389672	human	ensembl	74_37	+1	known	silent	c.2820	p.E940	1.000	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_SAM_type1,pfam_SAM_2,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt_N_dom,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	EPHA6	HGNC	ENSG00000080224	tier1	-	-	104	0	0.00	98	27	21.60						
ESR2	0	genome.wustl.edu	37	14	64749427	64749427	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	14	64749427	64749427	G	A	SNP	ESR2	ENST00000341099	human	ensembl	74_37	-1	known	missense	c.277	p.R93C	0.979	pfam_Estrogen_rcpt_beta_N	pfam_Nucl_hrmn_rcpt_lig-bd_core,pfam_Estrogen_rcpt_beta_N,pfam_Znf_hrmn_rcpt,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt	-	no_errors	ESR2	HGNC	ENSG00000140009	tier1	rs147382781	-	37	0	0.00	33	7	17.50						
RUNDC1	0	genome.wustl.edu	37	17	41143458	41143458	+	Missense_Mutation	SNP	G	G	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	17	41143458	41143458	G	T	SNP	RUNDC1	ENST00000361677	human	ensembl	74_37	+1	known	missense	c.1567	p.V523L	1.000	pfam_Run,pfscan_Run	pfam_Run,smart_Run,pfscan_Run	-	no_errors	RUNDC1	HGNC	ENSG00000198863	tier1	-	-	68	0	0.00	43	4	8.51						
ATP6V1E1	0	genome.wustl.edu	37	22	18082831	18082831	+	Missense_Mutation	SNP	T	T	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	22	18082831	18082831	T	A	SNP	ATP6V1E1	ENST00000253413	human	ensembl	74_37	-1	known	missense	c.397	p.I133F	0.996	pfam_ATPase_V1/A1-cplx_esu	pfam_ATPase_V1/A1-cplx_esu	-	no_errors	ATP6V1E1	HGNC	ENSG00000131100	tier1	-	-	204	0	0.00	205	34	14.23						
SUGP1	0	genome.wustl.edu	37	19	19407813	19407813	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	19	19407813	19407813	G	A	SNP	SUGP1	ENST00000247001	human	ensembl	74_37	-1	known	missense	c.1228	p.P410S	0.859	NULL	pfam_Surp,pfam_G_patch_dom,superfamily_Surp,smart_Surp,smart_G_patch_dom,pfscan_Surp,pfscan_G_patch_dom	-	no_errors	SUGP1	HGNC	ENSG00000105705	tier1	-	-	61	0	0.00	54	8	12.90						
GRM7	0	genome.wustl.edu	37	3	7494313	7494313	+	Missense_Mutation	SNP	A	A	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	3	7494313	7494313	A	T	SNP	GRM7	ENST00000402647	human	ensembl	74_37	+1	known	missense	c.1194	p.K398N	0.833	pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I	pfam_ANF_lig-bd_rcpt,pfam_GPCR_3_C,pfam_GPCR_3_9-Cys_dom,superfamily_Peripla_BP_I,pfscan_GPCR_3_C,prints_GPCR_3,prints_GPCR_3_mtglu_rcpt_7,prints_GPCR_3_mtglu_rcpt,prints_GPCR_3_mtglu_rcpt_4	-	no_errors	GRM7	HGNC	ENSG00000196277	tier1	-	-	26	0	0.00	87	17	16.35						
SLC30A3	0	genome.wustl.edu	37	2	27478187	27478188	+	Frame_Shift_Ins	INS	-	-	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	2	27478187	27478188	-	G	INS	SLC30A3	ENST00000233535	human	ensembl	74_37	-1	known	frame_shift_ins	c.1160_1159	p.Q387fs	0.986:0.942	NULL	pfam_Cation_efflux,tigrfam_Cation_efflux	-	no_errors	SLC30A3	HGNC	ENSG00000115194	tier1			47	0	0.00	33	3	8.33						
LUZP4	0	genome.wustl.edu	37	X	114541124	114541124	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	X	114541124	114541124	C	T	SNP	LUZP4	ENST00000371920	human	ensembl	74_37	+1	known	missense	c.697	p.R233C	0.001	NULL	NULL	-	no_errors	LUZP4	HGNC	ENSG00000102021	tier1	-	-	45	0	0.00	48	6	11.11						
HTT	0	genome.wustl.edu	37	4	3225176	3225176	+	Missense_Mutation	SNP	C	C	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	4	3225176	3225176	C	G	SNP	HTT	ENST00000355072	human	ensembl	74_37	+1	known	missense	c.7514	p.A2505G	1.000	NULL	pfam_Huntingtin_middle-repeat,pfam_HEAT,superfamily_ARM-type_fold,prints_Huntingtin	-	no_errors	HTT	HGNC	ENSG00000197386	tier1	-	-	54	0	0.00	57	10	14.93						
SGK223	0	genome.wustl.edu	37	8	8176387	8176388	+	In_Frame_Ins	INS	-	-	GGGGCG			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	8	8176387	8176388	-	GGGGCG	INS	SGK223	ENST00000330777	human	ensembl	74_37	-1	known	in_frame_ins	c.3498_3497	p.1170in_frame_insPA	0.000:0.034	pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,pfscan_Prot_kinase_dom	-	no_errors	SGK223	Uniprot_gn	ENSG00000182319	tier1														
FAM167A	0	genome.wustl.edu	37	8	11301807	11301807	+	Missense_Mutation	SNP	C	C	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	8	11301807	11301807	C	A	SNP	FAM167A	ENST00000284486	human	ensembl	74_37	-1	known	missense	c.114	p.R38S	1.000	NULL	pfam_FAM167	-	no_errors	FAM167A	HGNC	ENSG00000154319	tier1	-	-	65	0	0.00	58	24	29.27						
DUSP10	0	genome.wustl.edu	37	1	221875661	221875662	+	R	INS	-	-	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	1	221875661	221875662	-	A	INS	DUSP10	ENST00000468085	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001:0.040	-	-	-	no_errors	DUSP10	HGNC	ENSG00000143507	tier1			11	0	0.00	14	5	26.32						
PCDHB13	0	genome.wustl.edu	37	5	140595444	140595444	+	Silent	SNP	C	C	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	5	140595444	140595444	C	A	SNP	PCDHB13	ENST00000341948	human	ensembl	74_37	+1	known	silent	c.1749	p.G583	0.997	pfam_Cadherin,superfamily_Cadherin-like,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDHB13	HGNC	ENSG00000187372	tier1	-	-	82	0	0.00	54	7	11.48						
NTM	0	genome.wustl.edu	37	11	132205739	132205739	+	R	SNP	A	A	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	11	132205739	132205739	A	G	SNP	NTM	ENST00000474900	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.983	-	-	-	no_errors	NTM	HGNC	ENSG00000182667	tier1	-	-	52	0	0.00	24	7	22.58						
ENSG00000215972	0	genome.wustl.edu	37	10	127531562	127531562	+	R	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	10	127531562	127531562	G	A	SNP	ENSG00000215972	ENST00000401153	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.001	-	-	-	no_errors	AL360176.1	Clone_based_ensembl_gene	ENSG00000215972	tier1	-	-	87	0	0.00	62	10	13.70						
PRLR	0	genome.wustl.edu	37	5	35049444	35049444	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	5	35049444	35049444	C	T	SNP	PRLR	ENST00000231423	human	ensembl	74_37	-1	known	missense	c.1079	p.S360N	0.000	NULL	pfam_Growth/epo_recpt_lig-bind,pfam_IL-6_rcpt_alpha-bd,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	PRLR	HGNC	ENSG00000113494	tier1	-	-	45	0	0.00	67	8	10.67						
TP53	0	genome.wustl.edu	37	17	7578191	7578191	+	Missense_Mutation	SNP	A	A	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	17	7578191	7578191	A	G	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.658	p.Y220H	0.998	pfam_p53_D-bd,superfamily_p53-like_TF_D-bd,prints_p53_tumour_suppressor	pfam_p53_D-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_D-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	112	1	0.88	51	27	34.62						
ZNF652	0	genome.wustl.edu	37	17	47389375	47389375	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	17	47389375	47389375	C	T	SNP	ZNF652	ENST00000362063	human	ensembl	74_37	-1	known	missense	c.1078	p.E360K	1.000	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF652	HGNC	ENSG00000198740	tier1	-	-	37	0	0.00	36	7	16.28						
MUC17	0	genome.wustl.edu	37	7	100680100	100680100	+	Silent	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	7	100680100	100680100	G	A	SNP	MUC17	ENST00000306151	human	ensembl	74_37	+1	known	silent	c.5403	p.S1801	0.467	NULL	pfam_SEA_dom,smart_SEA_dom,pfscan_EG-like_dom,pfscan_SEA_dom	-	no_errors	MUC17	HGNC	ENSG00000169876	tier1	rs142682652	-	117	1	0.85	124	13	9.49						
LOC400743	0	genome.wustl.edu	37	1	17521055	17521056	+	R	DEL	CT	CT	-			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	CT	CT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	1	17521055	17521056	CT	-	DEL	LOC400743	ENST00000412427	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001:0.001	-	-	-	no_errors	RP11-380J14.1	Clone_based_vega_gene	ENSG00000204362	tier1			31	0	0.00	32	3	8.57						
OR2M3	0	genome.wustl.edu	37	1	248367161	248367161	+	Silent	SNP	T	T	C			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	1	248367161	248367161	T	C	SNP	OR2M3	ENST00000456743	human	ensembl	74_37	+1	known	silent	c.792	p.S264	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2M3	HGNC	ENSG00000228198	tier1	-	-	35	0	0.00	78	38	32.76						
ANKK1	0	genome.wustl.edu	37	11	113269853	113269853	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	11	113269853	113269853	G	A	SNP	ANKK1	ENST00000303941	human	ensembl	74_37	+1	known	missense	c.1162	p.V388M	0.025	superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Ankyrin_rpt-contain_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_Ankyrin_rpt,prints_Ankyrin_rpt,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Prot_kinase_dom	-	no_errors	ANKK1	HGNC	ENSG00000170209	tier1	-	-	61	0	0.00	44	27	38.03						
FAM47C	0	genome.wustl.edu	37	X	37027073	37027073	+	Missense_Mutation	SNP	G	G	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	X	37027073	37027073	G	T	SNP	FAM47C	ENST00000358047	human	ensembl	74_37	+1	known	missense	c.590	p.C197F	0.005	NULL	NULL	-	no_errors	FAM47C	HGNC	ENSG00000198173	tier1	rs149352851	-	192	0	0.00	140	405	74.31						
TMEM253	0	genome.wustl.edu	37	14	21571307	21571307	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	14	21571307	21571307	G	A	SNP	TMEM253	ENST00000418511	human	ensembl	74_37	+1	known	missense	c.544	p.E182K	0.695	NULL	NULL	-	no_errors	TMEM253	HGNC	ENSG00000232070	tier1	-	-	38	0	0.00	34	22	39.29						
FAM205B	0	genome.wustl.edu	37	9	34835945	34835945	+	R	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	9	34835945	34835945	G	A	SNP	FAM205B	ENST00000455647	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	FAM205B	HGNC	ENSG00000257198	tier1	-	-	23	0	0.00	23	5	17.86						
FEZF1	0	genome.wustl.edu	37	7	121943251	121943251	+	Missense_Mutation	SNP	G	G	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	7	121943251	121943251	G	T	SNP	FEZF1	ENST00000442488	human	ensembl	74_37	-1	known	missense	c.916	p.H306N	1.000	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	FEZF1	HGNC	ENSG00000128610	tier1	-	-	67	0	0.00	59	9	13.24						
TPRKB	0	genome.wustl.edu	37	2	73957880	73957881	+	R	INS	-	-	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	2	73957880	73957881	-	A	INS	TPRKB	ENST00000485758	human	ensembl	74_37	-1	putative	rna	NULL	NULL	0.000:0.004	-	-	-	no_errors	TPRKB	HGNC	ENSG00000144034	tier1			17	0	0.00	15	2	11.76						
KRTAP5-3	0	genome.wustl.edu	37	11	1628925	1628925	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	11	1628925	1628925	G	A	SNP	KRTAP5-3	ENST00000399685	human	ensembl	74_37	-1	known	missense	c.691	p.P231S	0.009	NULL	NULL	-	no_errors	KRTAP5-3	HGNC	ENSG00000196224	tier1	-	-	184	0	0.00	109	23	17.42						
BCMO1	0	genome.wustl.edu	37	16	81279115	81279115	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	16	81279115	81279115	C	T	SNP	BCMO1	ENST00000258168	human	ensembl	74_37	+1	known	missense	c.100	p.R34C	0.998	pfam_Carotenoid_Oase	pfam_Carotenoid_Oase	-	no_errors	BCMO1	HGNC	ENSG00000135697	tier1	rs201320081	GMAF=0.0005	59	0	0.00	49	12	19.67						
IGF2BP2	0	genome.wustl.edu	37	3	185414435	185414435	+	Frame_Shift_Del	DEL	A	A	-			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	3	185414435	185414435	A	-	DEL	IGF2BP2	ENST00000382199	human	ensembl	74_37	-1	known	frame_shift_del	c.305	p.L102fs	1.000	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom	pfam_KH_dom_type_1,pfam_RRM_dom,smart_RRM_dom,smart_KH_dom,pfscan_KH_dom_type_1,pfscan_RRM_dom	-	no_errors	IGF2BP2	HGNC	ENSG00000073792	tier1			19	0	0.00	27	3	10.00						
CCDC130	0	genome.wustl.edu	37	19	13865118	13865118	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	19	13865118	13865118	G	A	SNP	CCDC130	ENST00000221554	human	ensembl	74_37	+1	known	missense	c.19	p.V7I	0.211	pfam_CWC16	pfam_CWC16	-	no_errors	CCDC130	HGNC	ENSG00000104957	tier1	-	-	100	0	0.00	48	13	21.31						
C14orf105	0	genome.wustl.edu	37	14	57947400	57947400	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	14	57947400	57947400	C	T	SNP	C14orf105	ENST00000216445	human	ensembl	74_37	-1	known	missense	c.568	p.A190T	0.639	NULL	NULL	-	no_errors	C14orf105	HGNC	ENSG00000100557	tier1	-	-	54	0	0.00	71	9	11.11						
UBA3	0	genome.wustl.edu	37	3	69105348	69105348	+	Silent	SNP	G	G	C			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	3	69105348	69105348	G	C	SNP	UBA3	ENST00000361055	human	ensembl	74_37	-1	known	silent	c.1170	p.T390	0.998	pfam_E2_binding,superfamily_Molybdenum_cofac_synth_MoeB	pfam_ThiF_D_FAD-bd,pfam_E2_binding,pfam_UBact_repeat,pfam_Ubiquitin-activating_enzyme,superfamily_Molybdenum_cofac_synth_MoeB	-	no_errors	UBA3	HGNC	ENSG00000144744	tier1	-	-	68	0	0.00	69	11	13.75						
FLT4	0	genome.wustl.edu	37	5	180047941	180047941	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	5	180047941	180047941	C	T	SNP	FLT4	ENST00000261937	human	ensembl	74_37	-1	known	missense	c.2234	p.R745H	0.619	pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Ig_I-set,superfamily_Kinase-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,prints_VEGFR3_rcpt	-	no_errors	FLT4	HGNC	ENSG00000037280	tier1	rs184409663	GMAF=0.0005	58	0	0.00	30	4	11.76						
DMXL2	0	genome.wustl.edu	37	15	51828727	51828727	+	Silent	SNP	T	T	C			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	15	51828727	51828727	T	C	SNP	DMXL2	ENST00000543779	human	ensembl	74_37	-1	known	silent	c.1950	p.R650	0.822	NULL	pfam_Rav1p_C,pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	DMXL2	HGNC	ENSG00000104093	tier1	-	-	17	0	0.00	18	18	50.00						
FAM47B	0	genome.wustl.edu	37	X	34961413	34961413	+	Silent	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	X	34961413	34961413	C	T	SNP	FAM47B	ENST00000329357	human	ensembl	74_37	+1	known	silent	c.465	p.P155	0.113	NULL	NULL	-	no_errors	FAM47B	HGNC	ENSG00000189132	tier1	-	-	132	0	0.00	78	262	77.06						
CCDC110	0	genome.wustl.edu	37	4	186379436	186379436	+	Nonsense_Mutation	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	4	186379436	186379436	G	A	SNP	CCDC110	ENST00000307588	human	ensembl	74_37	-1	known	nonsense	c.2305	p.R769*	0.993	superfamily_4_helix_cytokine-like_core	superfamily_4_helix_cytokine-like_core	-	no_errors	CCDC110	HGNC	ENSG00000168491	tier1	rs199552759	GMAF=0.0005	28	0	0.00	45	12	21.05						
FAM92B	0	genome.wustl.edu	37	16	85141486	85141486	+	Missense_Mutation	SNP	A	A	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	16	85141486	85141486	A	T	SNP	FAM92B	ENST00000539556	human	ensembl	74_37	-1	known	missense	c.392	p.L131Q	1.000	pfam_FAM92	pfam_FAM92	-	no_errors	FAM92B	HGNC	ENSG00000153789	tier1	-	-	62	0	0.00	28	7	20.00						
ANKRD20A4	0	genome.wustl.edu	37	9	69423558	69423558	+	Silent	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	9	69423558	69423558	C	T	SNP	ANKRD20A4	ENST00000357336	human	ensembl	74_37	+1	known	silent	c.1854	p.S618	0.000	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt	-	no_errors	ANKRD20A4	HGNC	ENSG00000172014	tier1	rs199996482	-	19	0	0.00	81	20	19.80						
HEMK1	0	genome.wustl.edu	37	3	50609193	50609193	+	Missense_Mutation	SNP	T	T	C			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	3	50609193	50609193	T	C	SNP	HEMK1	ENST00000232854	human	ensembl	74_37	+1	known	missense	c.281	p.L94P	0.117	tigrfam_Release_fac_Glu-N5_MeTfrase,tigrfam_Modification_methylase_HemK	pfam_Small_mtfrase_dom,pfam_R_methylase_dom,pfam_Ribosomal-L11_MeTrfase_PrmA,pfam_R_MeTrfase_RsmD,pfam_Methyltransf_11,prints_D21N6_MeTrfase,tigrfam_Release_fac_Glu-N5_MeTfrase,tigrfam_Modification_methylase_HemK	-	no_errors	HEMK1	HGNC	ENSG00000114735	tier1	-	-	101	0	0.00	44	9	16.98						
HTN3	0	genome.wustl.edu	37	4	70897717	70897717	+	Splice_Site	SNP	G	G	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	4	70897717	70897717	G	T	SNP	HTN3	ENST00000526767	human	ensembl	74_37	+1	known	splice_site	c.72+1	e2+1	0.964	-	-	-	no_errors	HTN3	HGNC	ENSG00000205649	tier1	-	-	83	0	0.00	72	8	10.00						
TIA1	0	genome.wustl.edu	37	2	70443577	70443577	+	Missense_Mutation	SNP	T	T	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	2	70443577	70443577	T	A	SNP	TIA1	ENST00000433529	human	ensembl	74_37	-1	known	missense	c.638	p.N213I	1.000	NULL	pfam_RRM_dom,smart_RRM_dom_euk,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	TIA1	HGNC	ENSG00000116001	tier1	-	-	42	0	0.00	44	4	8.33						
COG4	0	genome.wustl.edu	37	16	70530315	70530315	+	Silent	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	16	70530315	70530315	G	A	SNP	COG4	ENST00000323786	human	ensembl	74_37	-1	known	silent	c.1501	p.L501	1.000	pfam_COG_su4,smart_COG_su4	pfam_COG_su4,smart_COG_su4	-	no_errors	COG4	HGNC	ENSG00000103051	tier1	-	-	55	0	0.00	45	5	10.00						
TTN	0	genome.wustl.edu	37	2	179439275	179439275	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	2	179439275	179439275	G	A	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	missense	c.63880	p.H21294Y	1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	15	0	0.00	47	10	17.54						
GTF2IRD2P1	0	genome.wustl.edu	37	7	72664015	72664016	+	R	INS	-	-	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	7	72664015	72664016	-	G	INS	GTF2IRD2P1	ENST00000425256	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.912:0.964	-	-	-	no_errors	GTF2IRD2P1	HGNC	ENSG00000214544	tier1			18	0	0.00	22	4	15.38						
NRXN1	0	genome.wustl.edu	37	2	50147836	50147853	+	R	DEL	GTGTGTGTGTGTGTGTGT	GTGTGTGTGTGTGTGTGT	-			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	GTGTGTGTGTGTGTGTGT	GTGTGTGTGTGTGTGTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	2	50147836	50147853	GTGTGTGTGTGTGTGTGT	-	DEL	NRXN1	ENST00000484192	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.001:0.005:0.106:0.113:0.127:0.107:0.109:0.093:0.096:0.025:0.055:0.070:0.324:0.354:0.283:0.295:0.258	-	-	-	no_errors	NRXN1	HGNC	ENSG00000179915	tier1														
SCOC	0	genome.wustl.edu	37	4	141302168	141302188	+	In_Frame_Del	DEL	AGAAAACCAAGTTCTTGGACA	AGAAAACCAAGTTCTTGGACA	-			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	AGAAAACCAAGTTCTTGGACA	AGAAAACCAAGTTCTTGGACA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	4	141302168	141302188	AGAAAACCAAGTTCTTGGACA	-	DEL	SCOC	ENST00000608372	human	ensembl	74_37	+1	known	in_frame_del	c.390_410	p.ENQVLGQ131in_frame_del	0.984:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:0.999:1.000:1.000:0.999:1.000:1.000	pfam_DUF2205_coiled-coil	pfam_DUF2205_coiled-coil	-	no_errors	SCOC	HGNC	ENSG00000153130	tier1														
MUC17	0	genome.wustl.edu	37	7	100680117	100680117	+	Missense_Mutation	SNP	T	T	C			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	7	100680117	100680117	T	C	SNP	MUC17	ENST00000306151	human	ensembl	74_37	+1	known	missense	c.5420	p.M1807T	0.000	NULL	pfam_SEA_dom,smart_SEA_dom,pfscan_EG-like_dom,pfscan_SEA_dom	-	no_errors	MUC17	HGNC	ENSG00000169876	tier1	rs147353603	-	108	0	0.00	122	13	9.63						
CAPN13	0	genome.wustl.edu	37	2	30987032	30987032	+	Missense_Mutation	SNP	G	G	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	2	30987032	30987032	G	T	SNP	CAPN13	ENST00000295055	human	ensembl	74_37	-1	known	missense	c.665	p.A222E	0.001	pfam_Peptidase_C2_calpain_cat,smart_Peptidase_C2_calpain_cat,pfscan_Peptidase_C2_calpain_cat	pfam_Peptidase_C2_calpain_cat,pfam_Calpain_domain_III,superfamily_Calpain_domain_III,smart_Peptidase_C2_calpain_cat,pfscan_Peptidase_C2_calpain_cat,prints_Calpain_cysteine_protease	-	no_errors	CAPN13	HGNC	ENSG00000162949	tier1	-	-	48	0	0.00	34	3	8.11						
ENSG00000250186	0	genome.wustl.edu	37	17	47482200	47482200	+	R	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	17	47482200	47482200	G	A	SNP	ENSG00000250186	ENST00000506504	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.893	-	-	-	no_errors	RP11-1079K10.4	Clone_based_vega_gene	ENSG00000250186	tier1	-	-	40	0	0.00	32	5	13.51						
IL1RN	0	genome.wustl.edu	37	2	113890420	113890420	+	Missense_Mutation	SNP	C	C	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	2	113890420	113890420	C	A	SNP	IL1RN	ENST00000259206	human	ensembl	74_37	+1	known	missense	c.515	p.T172N	1.000	pfam_IL-1,superfamily_Cytokine_IL1-like,smart_IL-1,prints_IL-1RA/IL-36	pfam_IL-1,superfamily_Cytokine_IL1-like,smart_IL-1,prints_IL-1RA/IL-36,prints_IL-1	-	no_errors	IL1RN	HGNC	ENSG00000136689	tier1	-	-	36	0	0.00	28	5	15.15						
MAPK10	0	genome.wustl.edu	37	4	87023109	87023109	+	Missense_Mutation	SNP	A	A	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	4	87023109	87023109	A	G	SNP	MAPK10	ENST00000359221	human	ensembl	74_37	-1	known	missense	c.502	p.Y168H	1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_LipoPS_kinase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_LipoPS_kinase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_MAPK_JNK,pfscan_Prot_kinase_dom	-	no_errors	MAPK10	HGNC	ENSG00000109339	tier1	-	-	20	0	0.00	35	33	48.53						
MTHFD1	0	genome.wustl.edu	37	14	64884678	64884679	+	Frame_Shift_Ins	INS	-	-	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	14	64884678	64884679	-	G	INS	MTHFD1	ENST00000216605	human	ensembl	74_37	+1	known	frame_shift_ins	c.551_552	p.L185fs	1.000:1.000	pfam_THF_DH/CycHdrlase_D-bd_dom	pfam_Formate_THF_ligase,pfam_THF_DH/CycHdrlase_D-bd_dom,pfam_THF_DH/CycHdrlase_cat_dom,superfamily_P-loop_NTPase,prints_THF_DH/CycHdrlase	-	no_errors	MTHFD1	HGNC	ENSG00000100714	tier1			59	0	0.00	34	9	20.93						
GON4L	0	genome.wustl.edu	37	1	155785776	155785777	+	R	INS	-	-	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	1	155785776	155785777	-	A	INS	GON4L	ENST00000471341	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	GON4L	HGNC	ENSG00000116580	tier1			29	0	0.00	49	7	12.50						
MIR629	0	genome.wustl.edu	37	15	70371803	70371803	+	R	SNP	A	A	G			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	15	70371803	70371803	A	G	SNP	MIR629	ENST00000385230	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MIR629	HGNC	ENSG00000207965	tier1	-	-	41	0	0.00	46	5	9.80						
ENSG00000273433	0	genome.wustl.edu	37	7	27192088	27192089	+	R	INS	-	-	GGCCT			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	7	27192088	27192089	-	GGCCT	INS	ENSG00000273433	ENST00000467897	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.007:0.074	-	-	-	no_errors	RP1-170O19.22	Clone_based_vega_gene	ENSG00000273433	tier1														
PNPLA7	0	genome.wustl.edu	37	9	140409907	140409907	+	Silent	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	9	140409907	140409907	C	T	SNP	PNPLA7	ENST00000406427	human	ensembl	74_37	-1	known	silent	c.1149	p.A383	0.224	NULL	pfam_cNMP-bd_dom,pfam_Patatin/PLipase_A2-rel,superfamily_Acyl_Trfase/lysoPLipase,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom	-	no_errors	PNPLA7	HGNC	ENSG00000130653	tier1	-	-	109	0	0.00	63	30	32.26						
NEFH	0	genome.wustl.edu	37	22	29884864	29884864	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	22	29884864	29884864	G	A	SNP	NEFH	ENST00000310624	human	ensembl	74_37	+1	known	missense	c.1235	p.R412Q	1.000	pfam_IF	pfam_IF,pfam_DUF1388	-	no_errors	NEFH	HGNC	ENSG00000100285	tier1	-	-	116	0	0.00	66	14	17.50						
COL4A3BP	0	genome.wustl.edu	37	5	74722305	74722306	+	Splice_Site	INS	-	-	A			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	5	74722305	74722306	-	A	INS	COL4A3BP	ENST00000380494	human	ensembl	74_37	-1	known	splice_site_ins	c.733-3_733-2	e5-2	1.000:0.996	-	-	-	no_errors	COL4A3BP	HGNC	ENSG00000113163	tier1			21	0	0.00	46	4	8.00						
KMT2C	0	genome.wustl.edu	37	7	151900117	151900117	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	7	151900117	151900117	C	T	SNP	KMT2C	ENST00000355193	human	ensembl	74_37	-1	known	missense	c.3994	p.D1332N	1.000	NULL	pfam_Znf_PHD-finger,pfam_SET_dom,pfam_FYrich_C,pfam_FYrich_N,superfamily_Znf_FYVE_PHD,superfamily_HMG_box_dom,smart_Znf_PHD,smart_Znf_RING,smart_HMG_box_dom,smart_FYrich_N,smart_FYrich_C,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_DHHC_palmitoyltrfase,pfscan_Znf_PHD-finger,pfscan_Znf_RING	-	no_errors	KMT2C	HGNC	ENSG00000055609	tier1	-	-	15	0	0.00	34	15	30.61						
GAPVD1	0	genome.wustl.edu	37	9	128025963	128025989	+	Splice_Site	DEL	CAGCACTCCATCTGTAGGTATGTCTGT	CAGCACTCCATCTGTAGGTATGTCTGT	-			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	CAGCACTCCATCTGTAGGTATGTCTGT	CAGCACTCCATCTGTAGGTATGTCTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	9	128025963	128025989	CAGCACTCCATCTGTAGGTATGTCTGT	-	DEL	GAPVD1	ENST00000469528	human	ensembl	74_37	+1	known	splice_site_del	c.NULL	NULL	1.000:1.000:1.000:1.000:1.000:0.999:0.996:0.980:0.970:0.963:0.961:0.959:0.952:0.948:0.947:0.950:0.961:0.966:0.966:0.969:0.974:0.982:0.984:0.985:0.984:0.985:0.993	-	-	-	no_errors	GAPVD1	HGNC	ENSG00000165219	tier1														
DENND5B	0	genome.wustl.edu	37	12	31648769	31648769	+	Missense_Mutation	SNP	G	G	C			TCGA-QQ-A5VA-01A-12D-A32I-09	TCGA-QQ-A5VA-11A-11D-A32I-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	785de115-c037-46d5-84c5-34a20ade7a78	52b82f28-4796-456a-8523-59c171707336	12	31648769	31648769	G	C	SNP	DENND5B	ENST00000306833	human	ensembl	74_37	-1	known	missense	c.317	p.P106R	1.000	pfam_uDENN_dom,smart_uDENN_dom,pfscan_uDENN_dom	pfam_DENN_dom,pfam_Run,pfam_uDENN_dom,pfam_dDENN_dom,pfam_PLAT/LH2_dom,superfamily_Lipase_LipOase,smart_uDENN_dom,smart_DENN_dom,smart_dDENN_dom,smart_Run,pfscan_DENN_dom,pfscan_uDENN_dom,pfscan_dDENN_dom,pfscan_PLAT/LH2_dom,pfscan_Run	-	no_errors	DENND5B	HGNC	ENSG00000170456	tier1	-	-	205	0	0.00	163	48	22.64