Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
OR13C5	0	genome.wustl.edu	37	9	107361256	107361256	+	Missense_Mutation	SNP	C	C	T			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	9	107361256	107361256	C	T	SNP	OR13C5	ENST00000374779	human	ensembl	74_37	-1	known	missense	c.439	p.G147R	0.012	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR13C5	HGNC	ENSG00000255800	tier1	-	-	65	0	0.00	36	13	26.53	53	0	0.00	59	43	42.16
IL13RA2	0	genome.wustl.edu	37	X	114248419	114248419	+	Missense_Mutation	SNP	C	C	T			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	X	114248419	114248419	C	T	SNP	IL13RA2	ENST00000243213	human	ensembl	74_37	-1	known	missense	c.434	p.C145Y	0.884	pfam_IL-6_rcpt_alpha-bd,superfamily_Fibronectin_type3	pfam_IL-6_rcpt_alpha-bd,superfamily_Fibronectin_type3	-	no_errors	IL13RA2	HGNC	ENSG00000123496	tier1	-	-	80	0	0.00	18	23	56.10	141	0	0.00	46	76	62.30
SERPINB9	0	genome.wustl.edu	37	6	2890727	2890727	+	Silent	SNP	A	A	G			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	6	2890727	2890727	A	G	SNP	SERPINB9	ENST00000380698	human	ensembl	74_37	-1	known	silent	c.801	p.V267	0.001	pfam_Serpin_dom,superfamily_Serpin_dom,smart_Serpin_dom,prints_Serpin_B9/Maspin	pfam_Serpin_dom,superfamily_Serpin_dom,smart_Serpin_dom,prints_Serpin_B9/Maspin	-	no_errors	SERPINB9	HGNC	ENSG00000170542	tier1	-	-	21	0	0.00	7	15	68.18	110	0	0.00	51	54	51.43
TRIM44	0	genome.wustl.edu	37	11	35828045	35828045	+	R	SNP	C	C	T			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	11	35828045	35828045	C	T	SNP	TRIM44	ENST00000532066	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	TRIM44	HGNC	ENSG00000166326	tier1	-	-	73	0	0.00	42	18	30.00	79	0	0.00	108	34	23.94
PCDH15	0	genome.wustl.edu	37	10	56129015	56129015	+	Silent	SNP	G	G	A			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	10	56129015	56129015	G	A	SNP	PCDH15	ENST00000320301	human	ensembl	74_37	-1	known	silent	c.339	p.S113	1.000	smart_Cadherin	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH15	HGNC	ENSG00000150275	tier1	-	-	59	0	0.00	23	16	41.03	70	0	0.00	22	39	63.93
CDK4	0	genome.wustl.edu	37	12	58145458	58145458	+	Missense_Mutation	SNP	C	C	G			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	12	58145458	58145458	C	G	SNP	CDK4	ENST00000257904	human	ensembl	74_37	-1	known	missense	c.43	p.G15R	0.999	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Aminoglycoside_PTrfase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	CDK4	HGNC	ENSG00000135446	tier1	-	-	27	0	0.00	9	5	35.71	80	0	0.00	78	26	25.00
LINC01010	0	genome.wustl.edu	37	6	134824057	134824057	+	R	SNP	A	A	G			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	6	134824057	134824057	A	G	SNP	LINC01010	ENST00000431422	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.013	-	-	-	no_errors	LINC01010	HGNC	ENSG00000236700	tier1	-	-	22	0	0.00	14	7	33.33	77	0	0.00	73	27	27.00
RGMB	0	genome.wustl.edu	37	5	98129279	98129279	+	Missense_Mutation	SNP	C	C	A			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	5	98129279	98129279	C	A	SNP	RGMB	ENST00000308234	human	ensembl	74_37	+1	known	missense	c.1259	p.T420N	1.000	pfam_RGM_C	pfam_RGM_C,pfam_RGM_N	-	no_errors	RGMB	HGNC	ENSG00000174136	tier1	-	-	50	0	0.00	30	22	42.31	65	0	0.00	78	42	35.00
PIGC	0	genome.wustl.edu	37	1	172411323	172411323	+	Missense_Mutation	SNP	T	T	A			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	1	172411323	172411323	T	A	SNP	PIGC	ENST00000258324	human	ensembl	74_37	-1	known	missense	c.440	p.D147V	1.000	pfam_Plno_Glcc_GPI2,pirsf_Plno_Glcc_GPI2	pfam_Plno_Glcc_GPI2,pirsf_Plno_Glcc_GPI2	-	no_errors	PIGC	HGNC	ENSG00000135845	tier1	-	-	16	0	0.00	10	8	44.44	52	0	0.00	62	43	40.95
C12orf55	0	genome.wustl.edu	37	12	97102550	97102550	+	Silent	SNP	C	C	T			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	12	97102550	97102550	C	T	SNP	C12orf55	ENST00000524981	human	ensembl	74_37	+1	putative	silent	c.6693	p.N2231	0.000	NULL	superfamily_Fibronectin_type3	-	no_errors	C12orf55	HGNC	ENSG00000188596	tier1	-	-	16	0	0.00	20	14	41.18	127	0	0.00	114	48	29.63
CLCN2	0	genome.wustl.edu	37	3	184071063	184071063	+	Missense_Mutation	SNP	G	G	A			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	3	184071063	184071063	G	A	SNP	CLCN2	ENST00000265593	human	ensembl	74_37	-1	known	missense	c.2003	p.T668I	0.990	NULL	pfam_Cl-channel_volt-gated,pfam_CBS_dom,superfamily_Cl-channel_core,prints_Cl-channel_volt-gated,prints_Cl-channel-2	-	no_errors	CLCN2	HGNC	ENSG00000114859	tier1	-	-	60	0	0.00	15	35	34.31	33	0	0.00	16	36	33.64
P2RX2	0	genome.wustl.edu	37	12	133198160	133198160	+	Missense_Mutation	SNP	G	G	A			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	12	133198160	133198160	G	A	SNP	P2RX2	ENST00000343948	human	ensembl	74_37	+1	known	missense	c.1096	p.G366R	0.000	NULL	pfam_P2X_purnocptor,prints_P2X2_purnocptor,prints_P2X_purnocptor,tigrfam_P2X_purnocptor	-	no_errors	P2RX2	HGNC	ENSG00000187848	tier1	rs199514327	-	43	0	0.00	23	14	37.84	42	0	0.00	58	38	39.58
OCIAD1	0	genome.wustl.edu	37	4	48835496	48835496	+	Missense_Mutation	SNP	G	G	C			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	4	48835496	48835496	G	C	SNP	OCIAD1	ENST00000264312	human	ensembl	74_37	+1	known	missense	c.137	p.R46T	1.000	pfam_OCIA	pfam_OCIA	-	no_errors	OCIAD1	HGNC	ENSG00000109180	tier1	-	-	45	0	0.00	39	26	40.00	75	0	0.00	84	30	26.32
SPTA1	0	genome.wustl.edu	37	1	158581004	158581004	+	R	SNP	T	T	C			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	1	158581004	158581004	T	C	SNP	SPTA1	ENST00000485680	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	SPTA1	HGNC	ENSG00000163554	tier1	-	-	32	0	0.00	17	10	37.04	106	0	0.00	123	75	37.31
ZNF729	0	genome.wustl.edu	37	19	22498491	22498491	+	Missense_Mutation	SNP	C	C	T			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	19	22498491	22498491	C	T	SNP	ZNF729	ENST00000601693	human	ensembl	74_37	+1	novel	missense	c.2272	p.H758Y	0.700	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF729	HGNC	ENSG00000196350	tier1	-	-	38	0	0.00	21	6	22.22	39	0	0.00	43	28	38.89
DARS	0	genome.wustl.edu	37	2	136742985	136742985	+	Missense_Mutation	SNP	C	C	A			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	2	136742985	136742985	C	A	SNP	DARS	ENST00000264161	human	ensembl	74_37	-1	known	missense	c.54	p.M18I	1.000	NULL	pfam_aa-tR-synt_II,pfam_-bd_OB_tR,superfamily_-bd_OB-fold,pfscan_aa-tR-synth_II,prints_Asp/Asn-tR-synth_IIb,tigrfam_Asp-tR_synthase	-	no_errors	DARS	HGNC	ENSG00000115866	tier1	-	-	111	0	0.00	71	42	37.17	45	0	0.00	52	38	42.22
DISP2	0	genome.wustl.edu	37	15	40661057	40661057	+	Missense_Mutation	SNP	C	C	T			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	15	40661057	40661057	C	T	SNP	DISP2	ENST00000267889	human	ensembl	74_37	+1	known	missense	c.2744	p.P915L	0.991	NULL	pfscan_SSD	-	no_errors	DISP2	HGNC	ENSG00000140323	tier1	-	-	55	0	0.00	35	18	33.96	72	0	0.00	74	41	35.65
NHS	0	genome.wustl.edu	37	X	17742527	17742527	+	Missense_Mutation	SNP	C	C	T			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	X	17742527	17742527	C	T	SNP	NHS	ENST00000380060	human	ensembl	74_37	+1	known	missense	c.1154	p.P385L	1.000	NULL	NULL	-	no_errors	NHS	HGNC	ENSG00000188158	tier1	-	-	32	0	0.00	25	5	16.67	144	0	0.00	157	18	10.29
TEX14	0	genome.wustl.edu	37	17	56679184	56679184	+	Missense_Mutation	SNP	A	A	G			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	17	56679184	56679184	A	G	SNP	TEX14	ENST00000240361	human	ensembl	74_37	-1	known	missense	c.1679	p.I560T	0.077	NULL	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Prot_kinase_dom	-	no_errors	TEX14	HGNC	ENSG00000121101	tier1	-	-	34	0	0.00	23	12	34.29	101	0	0.00	118	69	36.90
ENSG00000184566	0	genome.wustl.edu	37	11	33902977	33902977	+	Missense_Mutation	SNP	T	T	C			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	11	33902977	33902977	T	C	SNP	ENSG00000184566	ENST00000330381	human	ensembl	74_37	+1	known	missense	c.329	p.V110A	0.896	NULL	NULL	-	no_errors	AC132216.1	Clone_based_ensembl_gene	ENSG00000184566	tier1	-	-	19	0	0.00	9	7	43.75	130	0	0.00	117	81	40.91
TGM1	0	genome.wustl.edu	37	14	24727837	24727837	+	Missense_Mutation	SNP	A	A	C			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	14	24727837	24727837	A	C	SNP	TGM1	ENST00000206765	human	ensembl	74_37	-1	known	missense	c.1202	p.F401C	1.000	pfam_Transglutaminase-like,smart_Transglutaminase-like	pfam_Transglutaminase_C,pfam_Transglutaminase_N,pfam_Transglutaminase-like,superfamily_Ig_E-set,superfamily_Transglutaminase_C,smart_Transglutaminase-like	-	no_errors	TGM1	HGNC	ENSG00000092295	tier1	-	-	57	0	0.00	19	16	45.71	88	0	0.00	52	58	52.73
DLX1	0	genome.wustl.edu	37	2	172952850	172952850	+	Silent	SNP	C	C	G			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	2	172952850	172952850	C	G	SNP	DLX1	ENST00000361725	human	ensembl	74_37	+1	known	silent	c.633	p.P211	0.001	NULL	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom,prints_HTH_motif,prints_Homeobox_metazoa	-	no_errors	DLX1	HGNC	ENSG00000144355	tier1	-	-	47	0	0.00	23	9	28.12	64	0	0.00	56	32	35.56
CYP3A7	0	genome.wustl.edu	37	7	99314839	99314839	+	Missense_Mutation	SNP	C	C	T			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	7	99314839	99314839	C	T	SNP	CYP3A7	ENST00000336374	human	ensembl	74_37	-1	known	missense	c.482	p.R161K	0.046	pfam_Cyt_P450,superfamily_Cyt_P450	pfam_Cyt_P450,superfamily_Cyt_P450,prints_Cyt_P450_E_CYP3A,prints_Cyt_P450_E_grp-I,prints_Cyt_P450_E_grp-II,prints_Cyt_P450_E_grp-IV,prints_Cyt_P450,prints_Cyt_P450_B	-	no_errors	CYP3A7	HGNC	ENSG00000160870	tier1	-	-	51	0	0.00	39	7	15.22	88	0	0.00	129	16	11.03
ANKRD27	0	genome.wustl.edu	37	19	33137460	33137460	+	Missense_Mutation	SNP	A	A	G			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	19	33137460	33137460	A	G	SNP	ANKRD27	ENST00000306065	human	ensembl	74_37	-1	known	missense	c.275	p.V92A	1.000	NULL	pfam_Ankyrin_rpt,pfam_VPS9,superfamily_Ankyrin_rpt-contain_dom,smart_VPS9_subgr,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_VPS9,prints_Ankyrin_rpt	-	no_errors	ANKRD27	HGNC	ENSG00000105186	tier1	-	-	24	0	0.00	17	7	29.17	117	0	0.00	130	24	15.58
SUGP2	0	genome.wustl.edu	37	19	19136447	19136447	+	Missense_Mutation	SNP	G	G	C			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	19	19136447	19136447	G	C	SNP	SUGP2	ENST00000337018	human	ensembl	74_37	-1	known	missense	c.710	p.A237G	0.783	NULL	pfam_Surp,pfam_G_patch_dom,superfamily_Surp,smart_Surp,smart_G_patch_dom,pfscan_Surp,pfscan_G_patch_dom	-	no_errors	SUGP2	HGNC	ENSG00000064607	tier1	-	-	71	0	0.00	38	31	44.93	105	0	0.00	137	70	33.82
C10orf76	0	genome.wustl.edu	37	10	103783275	103783275	+	Missense_Mutation	SNP	C	C	G			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	10	103783275	103783275	C	G	SNP	C10orf76	ENST00000370033	human	ensembl	74_37	-1	known	missense	c.628	p.V210L	1.000	superfamily_ARM-type_fold	pfam_DUF1741,superfamily_ARM-type_fold	-	no_errors	C10orf76	HGNC	ENSG00000120029	tier1	-	-	28	0	0.00	9	11	55.00	130	0	0.00	29	45	60.81
REPS1	0	genome.wustl.edu	37	6	139265676	139265676	+	Missense_Mutation	SNP	G	G	T			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	6	139265676	139265676	G	T	SNP	REPS1	ENST00000450536	human	ensembl	74_37	-1	known	missense	c.712	p.P238T	1.000	NULL	smart_EPS15_homology,pfscan_EF_hand_dom,pfscan_EPS15_homology	-	no_errors	REPS1	HGNC	ENSG00000135597	tier1	-	-	34	0	0.00	15	14	48.28	107	0	0.00	126	73	36.68
GMEB1	0	genome.wustl.edu	37	1	29041385	29041386	+	R	INS	-	-	A			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	-	-	-	A	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	1	29041385	29041386	-	A	INS	GMEB1	ENST00000480454	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.437:0.252	-	-	-	no_errors	GMEB1	HGNC	ENSG00000162419	tier1			21	0	0.00	24	3	11.11	61	0	0.00	124	14	10.14
MAP7D1	0	genome.wustl.edu	37	1	36644133	36644133	+	Missense_Mutation	SNP	C	C	T			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	1	36644133	36644133	C	T	SNP	MAP7D1	ENST00000373151	human	ensembl	74_37	+1	known	missense	c.1822	p.R608C	1.000	pfam_MAP7	pfam_MAP7	-	no_errors	MAP7D1	HGNC	ENSG00000116871	tier1	-	-	50	0	0.00	12	26	68.42	6	0	0.00	8	16	66.67
DCAF7	0	genome.wustl.edu	37	17	61666515	61666515	+	Missense_Mutation	SNP	T	T	C			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	17	61666515	61666515	T	C	SNP	DCAF7	ENST00000310827	human	ensembl	74_37	+1	known	missense	c.1010	p.L337P	1.000	NULL	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	DCAF7	HGNC	ENSG00000136485	tier1	-	-	40	0	0.00	43	4	8.51	78	0	0.00	110	5	4.35
CCT6A	0	genome.wustl.edu	37	7	56129482	56129482	+	Missense_Mutation	SNP	G	G	T			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	7	56129482	56129482	G	T	SNP	CCT6A	ENST00000275603	human	ensembl	74_37	+1	known	missense	c.1390	p.V464F	1.000	pfam_Cpn60/TCP-1,superfamily_Cpn60/TCP-1,tigrfam_Chap_CCT_zeta	pfam_Cpn60/TCP-1,superfamily_Cpn60/TCP-1,superfamily_GroEL-like_apical_dom,prints_Chaperone_TCP-1,prints_Chaprnin_Cpn60,tigrfam_Chap_CCT_zeta	-	no_errors	CCT6A	HGNC	ENSG00000146731	tier1	-	-	42	0	0.00	49	7	12.50	24	0	0.00	51	4	7.27
ETV5	0	genome.wustl.edu	37	3	185797767	185797767	+	Silent	SNP	G	G	A			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	3	185797767	185797767	G	A	SNP	ETV5	ENST00000537818	human	ensembl	74_37	-1	known	silent	c.615	p.A205	0.587	pfam_ETS_PEA3_N	pfam_ETS_PEA3_N,pfam_Ets_dom,smart_Ets_dom,pfscan_Ets_dom,prints_Ets_dom	-	no_errors	ETV5	HGNC	ENSG00000244405	tier1	-	-	33	0	0.00	16	8	33.33	8	0	0.00	4	0	0.00
PNKP	0	genome.wustl.edu	37	19	50370442	50370442	+	Frame_Shift_Del	DEL	G	G	-			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	19	50370442	50370442	G	-	DEL	PNKP	ENST00000322344	human	ensembl	74_37	-1	known	frame_shift_del	c.20	p.P7fs	0.000	superfamily_SMAD_FHA_domain,tigrfam_PNK_3Pase_met	pfam_PNK3P,superfamily_HAD-like_dom,superfamily_SMAD_FHA_domain,superfamily_P-loop_NTPase,tigrfam_PNK_3Pase_met,tigrfam_Polynucleotide_phosphatase,tigrfam_HAD-SF_hydro_IIIA	-	no_errors	PNKP	HGNC	ENSG00000039650	tier1			11	0	0.00	11	2	15.38	6	0	0.00	6	0	0.00
ENSG00000216154	0	genome.wustl.edu	37	4	123928724	123928751	+	R	DEL	TGTGTGTGTGTGTGTGTGTGTGTGTGTG	TGTGTGTGTGTGTGTGTGTGTGTGTGTG	-			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	TGTGTGTGTGTGTGTGTGTGTGTGTGTG	TGTGTGTGTGTGTGTGTGTGTGTGTGTG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	4	123928724	123928751	TGTGTGTGTGTGTGTGTGTGTGTGTGTG	-	DEL	ENSG00000216154	ENST00000401335	human	ensembl	74_37	-1	novel	rna	NULL	NULL	0.008:0.004:0.004:0.003:0.003:0.003:0.005:0.006:0.007:0.007:0.007:0.006:0.005:0.003:0.004:0.003:0.005:0.006:0.012:0.017:0.021:0.026:0.029:0.032:0.035:0.037:0.038:0.039	-	-	-	no_errors	AC109357.1	Clone_based_ensembl_gene	ENSG00000216154	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
ENSG00000230615	0	genome.wustl.edu	37	1	44570004	44570004	+	R	SNP	T	T	G			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	1	44570004	44570004	T	G	SNP	ENSG00000230615	ENST00000434244	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	RP5-1198O20.4	Clone_based_vega_gene	ENSG00000230615	tier1	-	-	29	0	0.00	19	4	17.39	1	0	0.00	1	0	0.00
ENSG00000270726	0	genome.wustl.edu	37	X	155252987	155252988	+	R	INS	-	-	CAGCACCAC			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	X	155252987	155252988	-	CAGCACCAC	INS	ENSG00000270726	ENST00000285718	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.959:1.000	-	-	-	no_errors	AJ271736.10	Clone_based_vega_gene	ENSG00000270726	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
LINC00200	0	genome.wustl.edu	37	10	1205801	1205801	+	R	SNP	C	C	A			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	10	1205801	1205801	C	A	SNP	LINC00200	ENST00000425630	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.025	-	-	-	no_errors	LINC00200	HGNC	ENSG00000229205	tier1	rs12763661	-	35	0	0.00	17	5	22.73	0	0	0.00	0	1	100.00
MIR3689B	0	genome.wustl.edu	37	9	137742013	137742013	+	R	SNP	C	C	G			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	9	137742013	137742013	C	G	SNP	MIR3689B	ENST00000581772	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MIR3689B	HGNC	ENSG00000264163	tier1	rs71483239	-	41	0	0.00	25	7	21.88	0	0	0.00	1	0	0.00
RCVRN	0	genome.wustl.edu	37	17	9801316	9801317	+	R	INS	-	-	GTGTGTGC			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	17	9801316	9801317	-	GTGTGTGC	INS	RCVRN	ENST00000570909	human	ensembl	74_37	-1	putative	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	RCVRN	HGNC	ENSG00000109047	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
CYP2S1	0	genome.wustl.edu	37	19	41712320	41712320	+	Frame_Shift_Del	DEL	T	T	-			TCGA-MB-A5Y8-01A-11D-A29N-09	TCGA-MB-A5Y8-10A-01D-A29N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	ef3ebd13-0657-488a-b94a-c92dcb425306	2acedeb3-0a0d-4d72-b763-176d68e55d0e	19	41712320	41712320	T	-	DEL	CYP2S1	ENST00000310054	human	ensembl	74_37	+1	known	frame_shift_del	c.1442	p.F482fs	1.000	pfam_Cyt_P450,superfamily_Cyt_P450	pfam_Cyt_P450,superfamily_Cyt_P450,prints_Cyt_P450_E_grp-I,prints_Cyt_P450_E_grp-IV,prints_Cyt_P450,prints_Cyt_P450_E_grp-I_CYP2A-like,prints_Cyt_P450_E_grp-I_CYP2B-like,prints_Cyt_P450_B	-	no_errors	CYP2S1	HGNC	ENSG00000167600	tier1			24	0	0.00	19	2	9.52	76	0	0.00	87	2	2.25