Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
TGFBR1	0	genome.wustl.edu	37	9	101894898	101894898	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	9	101894898	101894898	C	G	SNP	TGFBR1	ENST00000374994	human	ensembl	74_37	+1	known	missense	c.451	p.R151G	1.000	superfamily_Quinolinate_PRibosylTrfase_C	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_TGF_beta_rcpt_GS,pfam_Activin_rcpt,superfamily_Kinase-like_dom,superfamily_Quinolinate_PRibosylTrfase_C,smart_TGF_beta_rcpt_GS,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	TGFBR1	HGNC	ENSG00000106799	tier1	-	-	49	0	0.00	22	13	37.14	72	0	0.00	47	24	33.33
PTPRC	0	genome.wustl.edu	37	1	198608430	198608430	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	1	198608430	198608430	C	G	SNP	PTPRC	ENST00000442510	human	ensembl	74_37	+1	known	missense	c.32	p.A11G	0.992	pirsf_Leukocyte_common_ag,pfam_PTP_recept_N	pirsf_Leukocyte_common_ag,pfam_Tyr_Pase_rcpt/non-rcpt,pfam_Leukocyte_common_ag,pfam_PTP_recept_N,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,prints_Tyr_Pase_rcpt/non-rcpt,pfscan_Fibronectin_type3,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt	-	no_errors	PTPRC	HGNC	ENSG00000081237	tier1	-	-	81	0	0.00	45	38	45.78	109	0	0.00	42	36	46.15
VPS13D	0	genome.wustl.edu	37	1	12382770	12382770	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	1	12382770	12382770	G	A	SNP	VPS13D	ENST00000358136	human	ensembl	74_37	+1	known	missense	c.7882	p.E2628K	0.993	superfamily_UBA-like	pfam_VPSAP_dom,pfam_UBA/Ts_N,superfamily_UBA-like,smart_UBA/transl_elong_EF1B_N_euk,pfscan_UBA/transl_elong_EF1B_N_euk	-	no_errors	VPS13D	HGNC	ENSG00000048707	tier1	-	-	30	0	0.00	29	24	45.28	107	0	0.00	113	41	26.28
ERH	0	genome.wustl.edu	37	14	69847207	69847207	+	R	SNP	C	C	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	14	69847207	69847207	C	A	SNP	ERH	ENST00000216520	human	ensembl	74_37	-1	putative	rna	NULL	NULL	1.000	-	-	-	no_errors	ERH	HGNC	ENSG00000100632	tier1	-	-	41	0	0.00	21	17	44.74	82	0	0.00	24	35	59.32
LINC00238	0	genome.wustl.edu	37	14	66965126	66965126	+	R	SNP	T	T	C			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	14	66965126	66965126	T	C	SNP	LINC00238	ENST00000359454	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.745	-	-	-	no_errors	LINC00238	HGNC	ENSG00000196553	tier1	-	-	29	0	0.00	18	5	21.74	104	0	0.00	44	16	26.67
ZNF695	0	genome.wustl.edu	37	1	247150681	247150681	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	1	247150681	247150681	G	T	SNP	ZNF695	ENST00000339986	human	ensembl	74_37	-1	known	missense	c.1136	p.P379Q	0.990	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF695	HGNC	ENSG00000197472	tier1	-	-	42	0	0.00	23	23	50.00	30	0	0.00	19	11	36.67
DMXL2	0	genome.wustl.edu	37	15	51791871	51791871	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	15	51791871	51791871	T	A	SNP	DMXL2	ENST00000543779	human	ensembl	74_37	-1	known	missense	c.3550	p.T1184S	1.000	NULL	pfam_Rav1p_C,pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	DMXL2	HGNC	ENSG00000104093	tier1	-	-	28	0	0.00	22	6	21.43	76	0	0.00	66	10	13.16
SH2D7	0	genome.wustl.edu	37	15	78393658	78393658	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	15	78393658	78393658	G	A	SNP	SH2D7	ENST00000409568	human	ensembl	74_37	+1	putative	missense	c.655	p.G219R	0.000	NULL	NULL	-	no_errors	SH2D7	HGNC	ENSG00000183476	tier1	rs202061655	-	32	0	0.00	29	10	25.64	45	0	0.00	29	22	43.14
DROSHA	0	genome.wustl.edu	37	5	31526229	31526229	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	5	31526229	31526229	G	A	SNP	DROSHA	ENST00000344624	human	ensembl	74_37	-1	known	nonsense	c.811	p.R271*	0.881	NULL	pfam_RNase_III_dom,pfam_dsR-bd_dom,superfamily_RNase_III_dom,smart_RNase_III_dom,smart_dsR-bd_dom,pfscan_dsR-bd_dom,pfscan_RNase_III_dom	-	no_errors	DROSHA	HGNC	ENSG00000113360	tier1	-	-	39	0	0.00	50	8	13.79	65	0	0.00	93	16	14.68
PITPNM1	0	genome.wustl.edu	37	11	67263036	67263036	+	Silent	SNP	C	C	T			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	11	67263036	67263036	C	T	SNP	PITPNM1	ENST00000356404	human	ensembl	74_37	-1	known	silent	c.2355	p.E785	0.996	pfam_DDHD,pfscan_DDHD	pfam_PI_transfer,pfam_DDHD,pfam_LNS2,superfamily_HAD-like_dom,smart_LNS2,pfscan_DDHD,prints_PI_transfer	-	no_errors	PITPNM1	HGNC	ENSG00000110697	tier1	-	-	59	0	0.00	45	52	53.61	14	0	0.00	12	7	36.84
COL5A3	0	genome.wustl.edu	37	19	10079110	10079110	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	19	10079110	10079110	T	C	SNP	COL5A3	ENST00000264828	human	ensembl	74_37	-1	known	missense	c.4265	p.D1422G	1.000	NULL	pfam_Collagen,pfam_Fib_collagen_C,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,smart_Fib_collagen_C	-	no_errors	COL5A3	HGNC	ENSG00000080573	tier1	-	-	29	0	0.00	34	15	30.61	40	0	0.00	16	15	48.39
WDYHV1	0	genome.wustl.edu	37	8	124453718	124453718	+	R	SNP	C	C	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	8	124453718	124453718	C	A	SNP	WDYHV1	ENST00000517609	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	WDYHV1	HGNC	ENSG00000156795	tier1	-	-	32	0	0.00	18	9	33.33	123	0	0.00	95	54	36.24
NNT	0	genome.wustl.edu	37	5	43702778	43702778	+	Silent	SNP	A	A	G			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	5	43702778	43702778	A	G	SNP	NNT	ENST00000264663	human	ensembl	74_37	+1	known	silent	c.3051	p.Q1017	0.944	pfam_DH_DH_b	pfam_DH_DH_b,pfam_AlaDH/PNT_D(H)-bd,pfam_AlaDH/PNT_N,tigrfam_DP_transhyd_a	-	no_errors	NNT	HGNC	ENSG00000112992	tier1	-	-	88	0	0.00	58	53	47.75	100	0	0.00	59	47	44.34
GRIK3	0	genome.wustl.edu	37	1	37271869	37271869	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	1	37271869	37271869	G	A	SNP	GRIK3	ENST00000373091	human	ensembl	74_37	-1	known	missense	c.2150	p.A717V	1.000	pfam_Iontro_glu_rcpt,pfam_SBP_bac_3,smart_Iontro_glu_rcpt	pfam_ANF_lig-bd_rcpt,pfam_Iontro_glu_rcpt,pfam_Glu_rcpt_Glu/Gly-bd,pfam_SBP_bac_3,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIK3	HGNC	ENSG00000163873	tier1	-	-	26	0	0.00	13	33	70.21	80	0	0.00	36	57	61.29
WARS	0	genome.wustl.edu	37	14	100828076	100828076	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	14	100828076	100828076	A	C	SNP	WARS	ENST00000355338	human	ensembl	74_37	-1	known	missense	c.282	p.S94R	0.939	NULL	pfam_aa-tR-synth_Ic,pfam_WHEP-TRS,superfamily_S15_NS1_R-bd,pfscan_WHEP-TRS,prints_Trp-tR-ligase,tigrfam_Trp-tR-ligase	-	no_errors	WARS	HGNC	ENSG00000140105	tier1	-	-	72	0	0.00	36	19	34.55	76	0	0.00	69	14	16.87
MYO18B	0	genome.wustl.edu	37	22	26286800	26286800	+	Silent	SNP	G	G	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	22	26286800	26286800	G	A	SNP	MYO18B	ENST00000335473	human	ensembl	74_37	+1	known	silent	c.4392	p.R1464	0.998	superfamily_tR-bd_arm	pfam_Myosin_head_motor_dom,superfamily_P-loop_NTPase,superfamily_tR-bd_arm,superfamily_Ribosomal_zn-bd,smart_Myosin_head_motor_dom,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYO18B	HGNC	ENSG00000133454	tier1	-	-	48	0	0.00	26	28	51.85	31	0	0.00	13	15	53.57
CRB1	0	genome.wustl.edu	37	1	197398635	197398635	+	Nonsense_Mutation	SNP	T	T	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	1	197398635	197398635	T	A	SNP	CRB1	ENST00000367400	human	ensembl	74_37	+1	known	nonsense	c.2733	p.C911*	1.000	pfam_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom	pfam_EG-like_dom,pfam_Laminin_G,pfam_EGF_extracell,pfam_EGF-like_Ca-bd_dom,superfamily_ConA-like_lec_gl_sf,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Laminin_G,pfscan_EG-like_dom,pfscan_Laminin_G	-	no_errors	CRB1	HGNC	ENSG00000134376	tier1	-	-	47	0	0.00	45	33	42.31	92	0	0.00	39	23	36.51
ADAM21P1	0	genome.wustl.edu	37	14	70713103	70713103	+	R	SNP	T	T	C			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	14	70713103	70713103	T	C	SNP	ADAM21P1	ENST00000530196	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	ADAM21P1	HGNC	ENSG00000235812	tier1	-	-	69	0	0.00	40	18	31.03	40	0	0.00	24	11	31.43
LOC440905	0	genome.wustl.edu	37	2	130792055	130792055	+	R	SNP	T	T	C			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	2	130792055	130792055	T	C	SNP	LOC440905	ENST00000444030	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.298	-	-	-	no_errors	AC018865.8	Clone_based_vega_gene	ENSG00000180178	tier1	-	-	52	0	0.00	42	16	27.59	35	0	0.00	28	4	12.50
BCLAF1	0	genome.wustl.edu	37	6	136599135	136599135	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	6	136599135	136599135	A	T	SNP	BCLAF1	ENST00000531224	human	ensembl	74_37	-1	known	missense	c.884	p.I295N	1.000	NULL	NULL	-	no_errors	BCLAF1	HGNC	ENSG00000029363	tier1	-	-	227	0	0.00	153	31	16.76	166	0	0.00	130	64	32.99
UGGT2	0	genome.wustl.edu	37	13	96513064	96513064	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	13	96513064	96513064	G	C	SNP	UGGT2	ENST00000376747	human	ensembl	74_37	-1	known	missense	c.3718	p.H1240D	1.000	NULL	pfam_UDP-g_GGtrans,pfam_Glyco_trans_8	-	no_errors	UGGT2	HGNC	ENSG00000102595	tier1	-	-	300	0	0.00	455	64	12.31	73	0	0.00	122	14	10.14
OR6C3	0	genome.wustl.edu	37	12	55725940	55725940	+	Silent	SNP	C	C	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	12	55725940	55725940	C	A	SNP	OR6C3	ENST00000379667	human	ensembl	74_37	+1	known	silent	c.456	p.T152	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR6C3	HGNC	ENSG00000205329	tier1	-	-	53	0	0.00	53	8	13.11	99	0	0.00	65	17	20.73
DH11	0	genome.wustl.edu	37	7	21698459	21698459	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	7	21698459	21698459	C	T	SNP	DH11	ENST00000328843	human	ensembl	74_37	+1	known	missense	c.5153	p.T1718M	0.655	pfam_Dynein_heavy_dom-2	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DH11	HGNC	ENSG00000105877	tier1	rs202034810	-	70	0	0.00	20	39	66.10	85	1	1.16	33	40	54.79
NPTX2	0	genome.wustl.edu	37	7	98256582	98256582	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	7	98256582	98256582	C	A	SNP	NPTX2	ENST00000265634	human	ensembl	74_37	+1	known	missense	c.994	p.L332M	1.000	pfam_Pentaxin,superfamily_ConA-like_lec_gl_sf,smart_Pentaxin	pfam_Pentaxin,superfamily_ConA-like_lec_gl_sf,smart_Pentaxin,prints_Pentaxin	-	no_errors	NPTX2	HGNC	ENSG00000106236	tier1	-	-	43	0	0.00	29	21	42.00	54	0	0.00	33	10	23.26
RUSC1-AS1	0	genome.wustl.edu	37	1	155290825	155290825	+	R	SNP	G	G	C			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	1	155290825	155290825	G	C	SNP	RUSC1-AS1	ENST00000450199	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.007	-	-	-	no_errors	RUSC1-AS1	HGNC	ENSG00000225855	tier1	-	-	23	0	0.00	14	19	57.58	52	0	0.00	22	20	47.62
DH6	0	genome.wustl.edu	37	2	84885458	84885458	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	2	84885458	84885458	C	T	SNP	DH6	ENST00000237449	human	ensembl	74_37	+1	known	missense	c.5800	p.R1934C	0.996	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DH6	HGNC	ENSG00000115423	tier1	-	-	94	0	0.00	95	47	33.10	90	0	0.00	79	43	35.25
ENSG00000253381	0	genome.wustl.edu	37	8	39961703	39961703	+	R	SNP	A	A	T			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	8	39961703	39961703	A	T	SNP	ENSG00000253381	ENST00000524098	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	RP11-359E19.1	Clone_based_vega_gene	ENSG00000253381	tier1	-	-	74	0	0.00	56	37	39.78	76	0	0.00	61	46	42.99
KALRN	0	genome.wustl.edu	37	3	124160810	124160810	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	3	124160810	124160810	C	T	SNP	KALRN	ENST00000360013	human	ensembl	74_37	+1	known	missense	c.3211	p.R1071W	1.000	NULL	pfam_DH-domain,pfam_Prot_kinase_dom,pfam_Spectrin_repeat,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Ig_V-set,pfam_Immunoglobulin,superfamily_Kinase-like_dom,superfamily_DH-domain,superfamily_Fibronectin_type3,superfamily_SH3_domain,superfamily_CRAL-TRIO_dom,smart_CRAL-TRIO_dom,smart_Spectrin/alpha-actinin,smart_DH-domain,smart_Pleckstrin_homology,smart_SH3_domain,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_CRAL-TRIO_dom,pfscan_Fibronectin_type3,pfscan_Pleckstrin_homology,pfscan_SH3_domain,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,pfscan_DH-domain	-	no_errors	KALRN	HGNC	ENSG00000160145	tier1	-	-	71	0	0.00	52	12	18.75	64	0	0.00	49	11	18.33
ELSPBP1	0	genome.wustl.edu	37	19	48517529	48517529	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	19	48517529	48517529	G	A	SNP	ELSPBP1	ENST00000339841	human	ensembl	74_37	+1	known	missense	c.172	p.V58M	0.000	pfam_FN_type2_col-bd,superfamily_Kringle-like,smart_FN_type2_col-bd,pfscan_FN_type2_col-bd	pfam_FN_type2_col-bd,superfamily_Kringle-like,smart_FN_type2_col-bd,pfscan_FN_type2_col-bd	-	no_errors	ELSPBP1	HGNC	ENSG00000169393	tier1	rs145096514	GMAF=0.0005	51	0	0.00	28	36	56.25	83	0	0.00	47	64	57.66
TLL2	0	genome.wustl.edu	37	10	98240208	98240208	+	Frame_Shift_Del	DEL	A	A	-			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	A	A	A	-	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	10	98240208	98240208	A	-	DEL	TLL2	ENST00000357947	human	ensembl	74_37	-1	known	frame_shift_del	c.184	p.W62fs	1.000	pirsf_BMP_1/tolloid-like	pirsf_BMP_1/tolloid-like,pfam_CUB_dom,pfam_Peptidase_M12A,pfam_EGF-like_Ca-bd_dom,superfamily_CUB_dom,smart_Peptidase_Metallo,smart_CUB_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,prints_Peptidase_M12A,pfscan_CUB_dom,pfscan_EG-like_dom	-	no_errors	TLL2	HGNC	ENSG00000095587	tier1			84	0	0.00	52	24	31.58	101	0	0.00	59	15	20.27
KMT2A	0	genome.wustl.edu	37	11	118352703	118352709	+	Frame_Shift_Del	DEL	TGGTCAT	TGGTCAT	-			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	TGGTCAT	TGGTCAT	TGGTCAT	-	TGGTCAT	TGGTCAT	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	11	118352703	118352709	TGGTCAT	-	DEL	KMT2A	ENST00000389506	human	ensembl	74_37	+1	known	frame_shift_del	c.3908_3914	p.L1303fs	0.014:0.002:0.006:0.000:0.001:0.000:0.001	pirsf_MeTrfase_trithorax	pfam_SET_dom,pfam_FYrich_C,pfam_Znf_PHD-finger,pfam_FYrich_N,pfam_Znf_CXXC,superfamily_Znf_FYVE_PHD,superfamily_Bromodomain,smart_Znf_PHD,smart_Bromodomain,smart_FYrich_N,smart_FYrich_C,smart_SET_dom,smart_Post-SET_dom,pirsf_MeTrfase_trithorax,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_PHD-finger,pfscan_Znf_CXXC,pfscan_Bromodomain	-	no_errors	KMT2A	HGNC	ENSG00000118058	tier1			105	0	0.00	26	11	29.73	105	0	0.00	26	11	29.73
ADAD2	0	genome.wustl.edu	37	16	84230349	84230349	+	Silent	SNP	C	C	T			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	16	84230349	84230349	C	T	SNP	ADAD2	ENST00000268624	human	ensembl	74_37	+1	known	silent	c.1869	p.A623	0.996	pfam_A_deamin,smart_A_deamin,pfscan_A_deamin	pfam_A_deamin,pfam_dsR-bd_dom,smart_A_deamin,pfscan_dsR-bd_dom,pfscan_A_deamin	-	no_errors	ADAD2	HGNC	ENSG00000140955	tier1	-	-	23	0	0.00	8	21	72.41	43	0	0.00	2	22	91.67
ATRX	0	genome.wustl.edu	37	X	76952083	76952084	+	Frame_Shift_Ins	INS	-	-	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	-	-	-	A	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	X	76952083	76952084	-	A	INS	ATRX	ENST00000373344	human	ensembl	74_37	-1	known	frame_shift_ins	c.352_351	p.M117fs	1.000:1.000	NULL	pfam_SNF2_N,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Znf_FYVE_PHD,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	ATRX	HGNC	ENSG00000085224	tier1			36	0	0.00	10	25	71.43	41	0	0.00	6	41	87.23
OR51D1	0	genome.wustl.edu	37	11	4661964	4661964	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	11	4661964	4661964	T	C	SNP	OR51D1	ENST00000357605	human	ensembl	74_37	+1	known	missense	c.944	p.V315A	0.008	NULL	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR51D1	HGNC	ENSG00000197428	tier1	-	-	49	0	0.00	54	6	9.84	95	0	0.00	56	6	9.68
OR6A2	0	genome.wustl.edu	37	11	6816255	6816255	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	11	6816255	6816255	C	A	SNP	OR6A2	ENST00000332601	human	ensembl	74_37	-1	known	missense	c.685	p.A229S	0.968	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR6A2	HGNC	ENSG00000184933	tier1	-	-	35	0	0.00	40	5	11.11	112	0	0.00	86	4	4.44
CDRT15L2	0	genome.wustl.edu	37	17	20483754	20483754	+	Silent	SNP	C	C	T			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	17	20483754	20483754	C	T	SNP	CDRT15L2	ENST00000399044	human	ensembl	74_37	+1	known	silent	c.558	p.G186	0.007	NULL	NULL	-	no_errors	CDRT15L2	HGNC	ENSG00000214819	tier1	-	-	13	0	0.00	30	11	26.83	35	1	2.78	36	28	43.75
C9orf62	0	genome.wustl.edu	37	9	138235877	138235877	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	9	138235877	138235877	T	C	SNP	C9orf62	ENST00000320778	human	ensembl	74_37	+1	putative	missense	c.83	p.L28P	0.001	NULL	NULL	-	no_errors	C9orf62	HGNC	ENSG00000178243	tier1	-	-	31	0	0.00	21	12	36.36	17	1	5.26	11	9	45.00
FAM109A	0	genome.wustl.edu	37	12	111800949	111800949	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	12	111800949	111800949	C	T	SNP	FAM109A	ENST00000361483	human	ensembl	74_37	-1	known	missense	c.322	p.A108T	0.999	pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	-	no_errors	FAM109A	HGNC	ENSG00000198324	tier1	-	-	27	0	0.00	14	3	17.65	4	0	0.00	9	0	0.00
FRMPD3	0	genome.wustl.edu	37	X	106846480	106846480	+	Silent	SNP	G	G	A			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	X	106846480	106846480	G	A	SNP	FRMPD3	ENST00000276185	human	ensembl	74_37	+1	known	silent	c.5310	p.Q1770	0.516	NULL	pfam_FERM_central,pfam_PDZ,superfamily_FERM_central,superfamily_PDZ,smart_PDZ,smart_Band_41_domain,pfscan_FERM_domain,pfscan_PDZ	-	no_errors	FRMPD3	HGNC	ENSG00000147234	tier1	-	-	29	0	0.00	39	4	9.30	0	0	0.00	6	0	0.00
TCERG1	0	genome.wustl.edu	37	5	145890060	145890060	+	Nonsense_Mutation	SNP	T	T	G			TCGA-DX-AB2P-01A-11D-A387-09	TCGA-DX-AB2P-10A-01D-A38A-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	229d1a12-6364-4b92-8764-35b6beafc697	6fb55b48-5d07-4cfe-b318-bdb9270807e7	5	145890060	145890060	T	G	SNP	TCERG1	ENST00000296702	human	ensembl	74_37	+1	known	nonsense	c.3152	p.L1051*	1.000	pfam_FF_domain,smart_FF_domain	pfam_FF_domain,pfam_WW_dom,superfamily_FF_domain,superfamily_WW_dom,smart_WW_dom,smart_FF_domain,pfscan_WW_dom	-	no_errors	TCERG1	HGNC	ENSG00000113649	tier1	-	-	39	0	0.00	71	8	10.13	54	0	0.00	50	2	3.85