Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
TTC16	0	genome.wustl.edu	37	9	130493785	130493785	+	R	SNP	A	A	G			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	9	130493785	130493785	A	G	SNP	TTC16	ENST00000488285	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	TTC16	HGNC	ENSG00000167094	tier1	-	-	25	0	0.00	19	5	20.83	78	0	0.00	54	20	26.67
DTX3	0	genome.wustl.edu	37	12	58002321	58002321	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	12	58002321	58002321	G	A	SNP	DTX3	ENST00000551632	human	ensembl	74_37	+1	known	missense	c.778	p.G260R	1.000	NULL	pfam_Znf_C3HC4_RING-type,smart_Znf_RING,pfscan_Znf_RING	-	no_errors	DTX3	HGNC	ENSG00000178498	tier1	-	-	80	0	0.00	386	321	45.40	75	0	0.00	550	377	40.58
GJD2	0	genome.wustl.edu	37	15	35044752	35044752	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	15	35044752	35044752	C	T	SNP	GJD2	ENST00000290374	human	ensembl	74_37	-1	known	missense	c.893	p.R298H	1.000	NULL	pfam_Connexin_N,pfam_Connexin_CCC,smart_Connexin_N,prints_Connexin,prints_Connexin36	-	no_errors	GJD2	HGNC	ENSG00000159248	tier1	-	-	106	0	0.00	57	20	25.97	85	0	0.00	52	36	40.91
FRS3	0	genome.wustl.edu	37	6	41745817	41745817	+	R	SNP	G	G	A			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	6	41745817	41745817	G	A	SNP	FRS3	ENST00000466420	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.538	-	-	-	no_errors	FRS3	HGNC	ENSG00000137218	tier1	-	-	86	0	0.00	985	210	17.56	82	0	0.00	1618	326	16.73
FL	0	genome.wustl.edu	37	X	153591107	153591107	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	X	153591107	153591107	C	T	SNP	FL	ENST00000369850	human	ensembl	74_37	-1	known	missense	c.2326	p.G776S	1.000	pfam_Filamin/ABP280_repeat-like,superfamily_Ig_E-set,smart_Filamin,pfscan_Filamin/ABP280_repeat-like	pfam_Filamin/ABP280_repeat-like,pfam_CH-domain,superfamily_CH-domain,superfamily_Ig_E-set,smart_CH-domain,smart_Filamin,pfscan_CH-domain,pfscan_Filamin/ABP280_repeat-like	-	no_errors	FL	HGNC	ENSG00000196924	tier1	-	-	182	0	0.00	43	98	69.50	51	0	0.00	13	26	66.67
MTTP	0	genome.wustl.edu	37	4	100521804	100521804	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	4	100521804	100521804	G	A	SNP	MTTP	ENST00000265517	human	ensembl	74_37	+1	known	missense	c.1150	p.D384N	0.190	pfam_Lipid_transpt_N,superfamily_Vitellinogen_superhlx,smart_Lipid_transpt_N,pfscan_Lipid_transpt_N	pfam_Lipid_transpt_N,superfamily_Vitellinogen_superhlx,superfamily_Lipid_transp_b-sht_shell,smart_Lipid_transpt_N,pfscan_Lipid_transpt_N	-	no_errors	MTTP	HGNC	ENSG00000138823	tier1	-	-	134	0	0.00	73	46	38.66	96	1	1.03	73	42	36.52
RTL1	0	genome.wustl.edu	37	14	101347411	101347411	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	14	101347411	101347411	C	T	SNP	RTL1	ENST00000534062	human	ensembl	74_37	-1	known	missense	c.3715	p.D1239N	1.000	NULL	pfam_Retrotrans_gag_dom,superfamily_Peptidase_aspartic_dom	-	no_errors	RTL1	HGNC	ENSG00000254656	tier1	-	-	136	0	0.00	83	43	33.86	40	0	0.00	23	8	25.81
NOTCH4	0	genome.wustl.edu	37	6	32188317	32188317	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	6	32188317	32188317	C	T	SNP	NOTCH4	ENST00000375023	human	ensembl	74_37	-1	known	missense	c.1024	p.V342M	1.000	pirsf_Notch,pfam_EGF-like_Ca-bd_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom	pirsf_Notch,pfam_EG-like_dom,pfam_Ankyrin_rpt,pfam_EGF-like_Ca-bd_dom,pfam_Notch_dom,pfam_Notch_NODP_dom,superfamily_Ankyrin_rpt-contain_dom,superfamily_Notch_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Notch_dom,smart_Ankyrin_rpt,prints_Notch_4,prints_Notch_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_EG-like_dom,pfscan_Notch_dom	-	no_errors	NOTCH4	HGNC	ENSG00000204301	tier1	rs144492578	-	111	0	0.00	41	42	50.60	70	1	1.41	45	35	43.75
ENSG00000267353	0	genome.wustl.edu	37	19	37266238	37266238	+	R	DEL	C	C	-			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	C	C	C	-	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	19	37266238	37266238	C	-	DEL	ENSG00000267353	ENST00000588717	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.043	-	-	-	no_errors	CTD-2162K18.3	Clone_based_vega_gene	ENSG00000267353	tier1			71	0	0.00	26	12	31.58	157	0	0.00	112	47	29.56
FAM163A	0	genome.wustl.edu	37	1	179783087	179783087	+	Silent	SNP	G	G	T			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	1	179783087	179783087	G	T	SNP	FAM163A	ENST00000341785	human	ensembl	74_37	+1	known	silent	c.267	p.G89	0.638	NULL	NULL	-	no_errors	FAM163A	HGNC	ENSG00000143340	tier1	-	-	78	0	0.00	34	26	43.33	13	0	0.00	7	11	61.11
HAUS7	0	genome.wustl.edu	37	X	152722238	152722238	+	R	SNP	C	C	T			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	X	152722238	152722238	C	T	SNP	HAUS7	ENST00000464993	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	HAUS7	HGNC	ENSG00000213397	tier1	-	-	25	0	0.00	2	12	85.71	11	0	0.00	0	11	100.00
RABEP1	0	genome.wustl.edu	37	17	5253801	5253801	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	17	5253801	5253801	G	A	SNP	RABEP1	ENST00000262477	human	ensembl	74_37	+1	known	nonsense	c.840	p.W280*	1.000	NULL	pfam_Rabaptin_coiled-coil,pfam_Rabaptin_Rab5-bd_dom,prints_Rabaptin	-	no_errors	RABEP1	HGNC	ENSG00000029725	tier1	-	-	74	0	0.00	44	5	10.20	130	0	0.00	157	17	9.77
C1QTNF1	0	genome.wustl.edu	37	17	77044218	77044219	+	R	INS	-	-	GCTGACCCCAGGGCTCAGCACCAG			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	17	77044218	77044219	-	GCTGACCCCAGGGCTCAGCACCAG	INS	C1QTNF1	ENST00000582625	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.002	-	-	-	no_errors	C1QTNF1	HGNC	ENSG00000173918	tier1			18	0	0.00	2	0	0.00	18	0	0.00	2	0	0.00
UPK3B	0	genome.wustl.edu	37	7	76144537	76144538	+	Frame_Shift_Ins	INS	-	-	GGGGCTGGGGGAGATGG			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	7	76144537	76144538	-	GGGGCTGGGGGAGATGG	INS	UPK3B	ENST00000257632	human	ensembl	74_37	+1	known	frame_shift_ins	c.932_933	p.G315fs	0.004:0.021	NULL	NULL	-	no_errors	UPK3B	HGNC	ENSG00000243566	tier1			5	0	0.00	2	0	0.00	5	0	0.00	2	0	0.00
ATXN8OS	0	genome.wustl.edu	37	13	70713513	70713533	+	R	DEL	CTACTGCTGCTGCTGCTGCTG	CTACTGCTGCTGCTGCTGCTG	-			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	CTACTGCTGCTGCTGCTGCTG	CTACTGCTGCTGCTGCTGCTG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	13	70713513	70713533	CTACTGCTGCTGCTGCTGCTG	-	DEL	ATXN8OS	ENST00000414504	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.001:0.001:0.001:0.001:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.001:0.000:0.000:0.000:0.000:0.000:0.001:0.000	-	-	-	no_errors	ATXN8OS	HGNC	ENSG00000230223	tier1			1	0	0.00	0	0	0.00	1	0	0.00	0	0	0.00
DEFB104B	0	genome.wustl.edu	37	8	7332563	7332563	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	8	7332563	7332563	T	C	SNP	DEFB104B	ENST00000316169	human	ensembl	74_37	-1	known	missense	c.28	p.I10V	0.005	NULL	NULL	-	no_errors	DEFB104B	HGNC	ENSG00000177023	tier1	rs200740890	-	27	0	0.00	28	4	12.50	1	0	0.00	2	0	0.00
ENSG00000263120	0	genome.wustl.edu	37	17	55062464	55062465	+	R	INS	-	-	GAAAA			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	17	55062464	55062465	-	GAAAA	INS	ENSG00000263120	ENST00000572877	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001:0.001	-	-	-	no_errors	RP5-1107A17.4	Clone_based_vega_gene	ENSG00000263120	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
GOLGA6L6	0	genome.wustl.edu	37	15	20740571	20740571	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	15	20740571	20740571	T	C	SNP	GOLGA6L6	ENST00000427390	human	ensembl	74_37	-1	known	missense	c.1179	p.I393M	0.096	prints_Tropomyosin	superfamily_Ribosomal_L7/12_C/ClpS-like,prints_Tropomyosin	-	no_errors	GOLGA6L6	HGNC	ENSG00000215405	tier1	rs200650686	-	14	0	0.00	7	3	30.00	0	0	0.00	0	0	0.00
LOC101928729	0	genome.wustl.edu	37	17	18286742	18286742	+	R	DEL	G	G	-			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	17	18286742	18286742	G	-	DEL	LOC101928729	ENST00000579352	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.026	-	-	-	no_errors	RP1-37N7.1	Clone_based_vega_gene	ENSG00000264177	tier1			25	0	0.00	19	2	9.52	0	0	0.00	0	0	0.00
RBMXL2	0	genome.wustl.edu	37	11	7110476	7110476	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	11	7110476	7110476	A	G	SNP	RBMXL2	ENST00000306904	human	ensembl	74_37	+1	known	missense	c.125	p.D42G	1.000	pfam_RRM_dom,smart_RRM_dom_euk,smart_RRM_dom,pfscan_RRM_dom	pfam_RRM_dom,pfam_RBM1CTR,smart_RRM_dom_euk,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	RBMXL2	HGNC	ENSG00000170748	tier1	-	-	72	0	0.00	60	6	9.09	90	0	0.00	91	3	3.19
SLC17A6	0	genome.wustl.edu	37	11	22363276	22363276	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	11	22363276	22363276	G	A	SNP	SLC17A6	ENST00000263160	human	ensembl	74_37	+1	known	missense	c.289	p.D97N	1.000	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	SLC17A6	HGNC	ENSG00000091664	tier1	-	-	212	0	0.00	160	18	10.11	62	0	0.00	84	3	3.45
OR8B8	0	genome.wustl.edu	37	11	124310339	124310339	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A6BH-01A-12D-A307-09	TCGA-DX-A6BH-10A-01D-A307-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	98f225b0-b093-4073-98ee-cbd5999e7912	2c5832b3-1c6f-4176-8191-6d4b43a5391e	11	124310339	124310339	A	G	SNP	OR8B8	ENST00000328064	human	ensembl	74_37	-1	known	missense	c.643	p.F215L	0.998	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR8B8	HGNC	ENSG00000197125	tier1	-	-	88	0	0.00	40	4	9.09	131	0	0.00	110	2	1.79