Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
DSCR10	0	broad.mit.edu	37	21	39580548	39580548	+	RNA	SNP	C	C	T			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr21:39580548C>T	ENST00000432141.1	+	0	670					NR_027695.1																						TGTGGGTTTGCCATCGAAGGA	0.413000													4	149					0	0	1	0	0
DLG2	1740	broad.mit.edu	37	11	84245658	84245658	+	Silent	SNP	T	T	C			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr11:84245658T>C	ENST00000398309.2	-	2	629	c.159A>G	c.(157-159)gaA>gaG	p.E53E	DLG2_ENST00000376104.2_Silent_p.E158E|DLG2_ENST00000532653.1_Silent_p.E53E|DLG2_ENST00000524982.1_Silent_p.E53E|DLG2_ENST00000543673.1_Silent_p.E158E	NM_001364.3	NP_001355.2	Q15700	DLG2_HUMAN	discs, large homolog 2 (Drosophila)	53						cell junction|postsynaptic density|postsynaptic membrane	guanylate kinase activity|protein binding			breast(1)|central_nervous_system(1)|endometrium(8)|kidney(3)|large_intestine(11)|lung(35)|ovary(3)|pancreas(2)|skin(3)|upper_aerodigestive_tract(3)|urinary_tract(1)	71		all_cancers(6;0.00791)|Acute lymphoblastic leukemia(157;4.44e-05)|all_hematologic(158;0.0036)				CATGGACATTTTCTATTTGAG	0.418000													4	81					0	0	1	0	0
USP24	23358	broad.mit.edu	37	1	55572934	55572934	+	Missense_Mutation	SNP	A	A	C			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr1:55572934A>C	ENST00000294383.6	-	40	4739	c.4740T>G	c.(4738-4740)tgT>tgG	p.C1580W	USP24_ENST00000407756.1_Missense_Mutation_p.C1420W	NM_015306.2	NP_056121.2	Q9UPU5	UBP24_HUMAN	ubiquitin specific peptidase 24	1580					ubiquitin-dependent protein catabolic process		binding|cysteine-type peptidase activity|ubiquitin thiolesterase activity			breast(4)|cervix(1)|endometrium(8)|kidney(13)|large_intestine(7)|lung(16)|ovary(6)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(2)	60						TTTCTGCCCCACAGAGTGAAA	0.453000													5	49					0	0	1	0	0
SLC6A6	6533	broad.mit.edu	37	3	14508027	14508027	+	Missense_Mutation	SNP	G	G	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr3:14508027G>A	ENST00000454876.2	+	7	1065	c.736G>A	c.(736-738)Gtc>Atc	p.V246I	SLC6A6_ENST00000360861.3_Missense_Mutation_p.V246I			P31641	SC6A6_HUMAN	solute carrier family 6 (neurotransmitter transporter), member 6	246					cellular amino acid metabolic process	integral to plasma membrane	amino acid transmembrane transporter activity|neurotransmitter:sodium symporter activity|taurine:sodium symporter activity			NS(1)|breast(2)|central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(5)|lung(11)|ovary(1)|prostate(1)|skin(2)	28						CTTGCAGGTCGTCTACTTCAC	0.602000													8	49					0	0	1	0	0
TMPRSS15	5651	broad.mit.edu	37	21	19715874	19715874	+	Silent	SNP	T	T	C			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr21:19715874T>C	ENST00000284885.3	-	12	1410	c.1377A>G	c.(1375-1377)ggA>ggG	p.G459G		NM_002772.2	NP_002763.2	P98073	ENTK_HUMAN	transmembrane protease, serine 15	459	MAM.				proteolysis	brush border|integral to membrane	scavenger receptor activity|serine-type endopeptidase activity			NS(1)|breast(2)|cervix(1)|endometrium(4)|kidney(7)|large_intestine(19)|lung(36)|ovary(6)|prostate(3)|skin(5)|upper_aerodigestive_tract(1)	85						TCCAATTGTCTCCATAATTTC	0.294000													7	91					0	0	1	0	0
MX2	4600	broad.mit.edu	37	21	42748856	42748856	+	Nonsense_Mutation	SNP	G	G	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr21:42748856G>A	ENST00000330714.3	+	2	207	c.23G>A	c.(22-24)tGg>tAg	p.W8*	MX2_ENST00000543692.1_Nonsense_Mutation_p.W8*	NM_002463.1	NP_002454.1	P20592	MX2_HUMAN	myxovirus (influenza virus) resistance 2 (mouse)	8					response to virus|type I interferon-mediated signaling pathway	cytoplasm|nucleus	GTP binding|GTPase activity			breast(2)|endometrium(3)|large_intestine(6)|lung(12)|ovary(2)|prostate(3)|skin(2)|stomach(1)|upper_aerodigestive_tract(3)	34		Prostate(19;1.57e-07)|all_epithelial(19;0.0222)				CACAAGCCTTGGCCCTACCGG	0.512000													4	51					0	0	1	0	0
RBM34	23029	broad.mit.edu	37	1	235295210	235295210	+	Missense_Mutation	SNP	G	G	T			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr1:235295210G>T	ENST00000408888.3	-	11	1341	c.1111C>A	c.(1111-1113)Caa>Aaa	p.Q371K	RBM34_ENST00000366606.3_Missense_Mutation_p.Q366K|RBM34_ENST00000495224.1_5'UTR			P42696	RBM34_HUMAN	RNA binding motif protein 34	371						nucleolus	nucleotide binding|RNA binding			central_nervous_system(1)	1	Ovarian(103;0.0398)	all_cancers(173;0.177)|Prostate(94;0.0166)	OV - Ovarian serous cystadenocarcinoma(106;5.43e-05)|Epithelial(3;0.000121)			TTTGAATTTTGTTGTTTAAAT	0.328000													7	55					0.00448238	0.00458425	1	1	0
RALGAPB	57148	broad.mit.edu	37	20	37153536	37153536	+	Missense_Mutation	SNP	G	G	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr20:37153536G>A	ENST00000262879.6	+	11	2019	c.1735G>A	c.(1735-1737)Gat>Aat	p.D579N	RALGAPB_ENST00000397040.1_Missense_Mutation_p.D579N|RALGAPB_ENST00000397038.1_Missense_Mutation_p.D357N|RALGAPB_ENST00000397042.3_Missense_Mutation_p.D579N			Q86X10	RLGPB_HUMAN	Ral GTPase activating protein, beta subunit (non-catalytic)	579					activation of Ral GTPase activity	intracellular	protein heterodimerization activity|Ral GTPase activator activity			breast(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(8)|lung(29)|ovary(1)|pancreas(1)|prostate(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(2)	65						GAAAGGGATTGATGTTGTGGT	0.403000													24	130					0	0	1	0	0
CROCCP2	0	broad.mit.edu	37	1	16945452	16945452	+	RNA	SNP	C	C	T	rs11260834		TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr1:16945452C>T	ENST00000412962.1	-	0	2067																											CTCCCTACGACGGCAGGCCTA	0.647000													4	64					0	0	1	0	0
FBP1	2203	broad.mit.edu	37	9	97365824	97365824	+	Missense_Mutation	SNP	C	C	G			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr9:97365824C>G	ENST00000415431.1	-	8	1085	c.856G>C	c.(856-858)Gcc>Ccc	p.A286P	FBP1_ENST00000375326.4_Missense_Mutation_p.A286P	NM_001127628.1	NP_001121100.1	P09467	F16P1_HUMAN	fructose-1,6-bisphosphatase 1	286					gluconeogenesis	cytosol	fructose 1,6-bisphosphate 1-phosphatase activity|fructose-2,6-bisphosphate 2-phosphatase activity|identical protein binding|metal ion binding			kidney(1)|liver(1)|lung(1)	3		Acute lymphoblastic leukemia(62;0.136)			Adenosine monophosphate(DB00131)	ATGACGTAGGCCATGGGGTTG	0.537000											OREG0019330	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	28					0	0	1	0	0
PPP4C	5531	broad.mit.edu	37	16	30093814	30093814	+	Missense_Mutation	SNP	G	G	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr16:30093814G>A	ENST00000279387.7	+	4	328	c.160G>A	c.(160-162)Gac>Aac	p.D54N	PPP4C_ENST00000561610.1_Missense_Mutation_p.D54N	NM_002720.1	NP_002711.1	P60510	PP4C_HUMAN	protein phosphatase 4, catalytic subunit	54					microtubule cytoskeleton organization|regulation of double-strand break repair via homologous recombination	centrosome|nucleus	metal ion binding|NF-kappaB-inducing kinase activity|protein binding|protein serine/threonine phosphatase activity			central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(1)|liver(2)|lung(2)|pancreas(1)|skin(1)|urinary_tract(1)	9						GGTGTGCGGCGACATCCATGG	0.522000													6	62					0	0	1	0	0
KCNT1	57582	broad.mit.edu	37	9	138641963	138641963	+	Missense_Mutation	SNP	G	G	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr9:138641963G>A	ENST00000298480.5	+	3	348	c.274G>A	c.(274-276)Gtc>Atc	p.V92I	KCNT1_ENST00000490355.2_Missense_Mutation_p.V73I|KCNT1_ENST00000486577.2_Missense_Mutation_p.V53I|KCNT1_ENST00000487664.1_Missense_Mutation_p.V44I|KCNT1_ENST00000263604.3_Missense_Mutation_p.V73I|KCNT1_ENST00000488444.2_Missense_Mutation_p.V73I|KCNT1_ENST00000371757.2_Missense_Mutation_p.V92I|KCNT1_ENST00000491806.2_Missense_Mutation_p.V59I			B7ZVY4	B7ZVY4_HUMAN	potassium channel, subfamily T, member 1	92						membrane	binding|calcium-activated potassium channel activity			breast(2)|central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(8)|lung(18)|ovary(1)|pancreas(3)|prostate(5)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(2)	50		Myeloproliferative disorder(178;0.0821)		OV - Ovarian serous cystadenocarcinoma(145;2.11e-07)|Epithelial(140;1.57e-06)|all cancers(34;9.22e-05)		GGAGTTCTACGTCAACGAGAA	0.607000													4	45					0	0	1	0	0
VPS18	57617	broad.mit.edu	37	15	41192034	41192034	+	Missense_Mutation	SNP	G	G	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr15:41192034G>A	ENST00000220509.5	+	4	1357	c.1018G>A	c.(1018-1020)Gca>Aca	p.A340T	VPS18_ENST00000558474.1_Intron	NM_020857.2	NP_065908.1	Q9P253	VPS18_HUMAN	vacuolar protein sorting 18 homolog (S. cerevisiae)	340					endosome organization|lysosome organization|protein transport	HOPS complex|late endosome membrane|lysosomal membrane	metal ion binding|protein binding			autonomic_ganglia(1)|endometrium(5)|kidney(4)|large_intestine(4)|lung(6)|ovary(2)|prostate(2)|skin(3)|upper_aerodigestive_tract(1)	28		all_cancers(109;1.35e-17)|all_epithelial(112;3.78e-15)|Lung NSC(122;9.68e-11)|all_lung(180;2.25e-09)|Melanoma(134;0.0574)|Ovarian(310;0.0822)|Colorectal(260;0.0946)		GBM - Glioblastoma multiforme(113;1.07e-05)|COAD - Colon adenocarcinoma(120;0.15)|BRCA - Breast invasive adenocarcinoma(123;0.164)		GCTGCTACTGGCAGACCGGGT	0.632000													4	63					0	0	1	0	0
CCP110	9738	broad.mit.edu	37	16	19547945	19547945	+	Silent	SNP	T	T	G			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr16:19547945T>G	ENST00000396212.2	+	5	1390	c.954T>G	c.(952-954)gcT>gcG	p.A318A	CCP110_ENST00000396208.2_Silent_p.A318A|CCP110_ENST00000381396.5_Silent_p.A318A	NM_014711.4	NP_055526.3	O43303	CP110_HUMAN	centriolar coiled coil protein 110kDa	318					centriole replication|G2/M transition of mitotic cell cycle|regulation of cytokinesis	centriole|cytosol	protein binding			breast(2)|endometrium(2)|kidney(2)|large_intestine(3)|lung(8)|stomach(3)|urinary_tract(1)	21						CAGTTTTAGCTAGCTTTTCGA	0.393000													5	70					0	0	1	0	0
PNLIP	5406	broad.mit.edu	37	10	118315007	118315007	+	Missense_Mutation	SNP	G	G	A	rs62623373		TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr10:118315007G>A	ENST00000369221.2	+	8	827	c.799G>A	c.(799-801)Gga>Aga	p.G267R		NM_000936.2	NP_000927.1	P16233	LIPP_HUMAN	pancreatic lipase	267					lipid catabolic process|retinoid metabolic process|steroid metabolic process	extracellular region	retinyl-palmitate esterase activity|triglyceride lipase activity			central_nervous_system(1)|endometrium(2)|kidney(3)|large_intestine(6)|liver(2)|lung(22)|ovary(2)|skin(4)|upper_aerodigestive_tract(1)	43				all cancers(201;0.0131)	Bentiromide(DB00522)|Orlistat(DB01083)	GGACATAGACGGAATCTGGGA	0.398000													7	118					0	0	1	0	0
USP9X	8239	broad.mit.edu	37	X	40988337	40988337	+	Nonsense_Mutation	SNP	G	G	T			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chrX:40988337G>T	ENST00000324545.7	+	3	814	c.181G>T	c.(181-183)Gaa>Taa	p.E61*	USP9X_ENST00000378308.2_Nonsense_Mutation_p.E61*	NM_001039590.2|NM_001039591.2	NP_001034679.2|NP_001034680.2	Q93008	USP9X_HUMAN	ubiquitin specific peptidase 9, X-linked	61					BMP signaling pathway|cell division|chromosome segregation|female gamete generation|mitosis|protein deubiquitination|transforming growth factor beta receptor signaling pathway|ubiquitin-dependent protein catabolic process	cytoplasm	co-SMAD binding|cysteine-type endopeptidase activity|ubiquitin thiolesterase activity			NS(3)|breast(6)|central_nervous_system(1)|endometrium(14)|haematopoietic_and_lymphoid_tissue(3)|kidney(6)|large_intestine(16)|lung(29)|ovary(2)|prostate(3)|skin(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	87						ACCACAGCTTGAAGATGAGGA	0.458000													6	27					8.12818e-05	8.50624e-05	1	1	0
VSTM2A	222008	broad.mit.edu	37	7	54617693	54617693	+	Missense_Mutation	SNP	G	G	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr7:54617693G>A	ENST00000302287.3	+	4	870	c.464G>A	c.(463-465)cGc>cAc	p.R155H	VSTM2A_ENST00000402613.3_Missense_Mutation_p.R155H|VSTM2A_ENST00000407838.3_Missense_Mutation_p.R155H|VSTM2A_ENST00000498834.1_3'UTR|VSTM2A_ENST00000404951.1_Missense_Mutation_p.R155H|VSTM2A_ENST00000402026.2_Missense_Mutation_p.R154H			Q8TAG5	VTM2A_HUMAN	V-set and transmembrane domain containing 2A	155						extracellular region				endometrium(1)|large_intestine(2)|lung(12)|prostate(1)	16			STAD - Stomach adenocarcinoma(5;0.0525)			AGCCATGCCCGCAGAATGCAG	0.582000													5	15					0	0	1	0	0
ZNF841	284371	broad.mit.edu	37	19	52569155	52569155	+	Silent	SNP	T	T	C			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr19:52569155T>C	ENST00000389534.4	-	7	2439	c.1980A>G	c.(1978-1980)aaA>aaG	p.K660K	ZNF841_ENST00000594295.1_Silent_p.K660K|ZNF841_ENST00000359973.2_Intron|ZNF841_ENST00000426391.2_Silent_p.K544K|ZNF432_ENST00000598446.1_Intron	NM_001136499.1	NP_001129971.1	Q6ZN19	ZN841_HUMAN	zinc finger protein 841	544					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|endometrium(4)|kidney(3)|lung(3)	11						GAGTATAGGCTTTGCCACAAT	0.413000													12	66					0	0	1	0	0
TRAPPC12	51112	broad.mit.edu	37	2	3391659	3391659	+	Missense_Mutation	SNP	C	C	T			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr2:3391659C>T	ENST00000324266.5	+	2	460	c.265C>T	c.(265-267)Cgg>Tgg	p.R89W	TRAPPC12_ENST00000382110.2_Missense_Mutation_p.R89W	NM_016030.5	NP_057114.5	Q8WVT3	TTC15_HUMAN	trafficking protein particle complex 12	89							binding										GGGCCGAGTGCGGGACGAAGC	0.711000													2	2					0	0	1	0	0
MUC16	94025	broad.mit.edu	37	19	9057373	9057373	+	Silent	SNP	A	A	G			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr19:9057373A>G	ENST00000397910.4	-	3	30276	c.30073T>C	c.(30073-30075)Ttg>Ctg	p.L10025L		NM_024690.2	NP_078966.2	Q8WXI7	MUC16_HUMAN	mucin 16, cell surface associated	10027	Ser-rich.|Thr-rich.				cell adhesion	extracellular space|extrinsic to membrane|integral to membrane|plasma membrane	protein binding			NS(9)|autonomic_ganglia(1)|breast(26)|central_nervous_system(11)|cervix(1)|endometrium(46)|haematopoietic_and_lymphoid_tissue(5)|kidney(35)|large_intestine(91)|liver(1)|lung(278)|ovary(17)|pancreas(2)|prostate(17)|skin(18)|soft_tissue(1)|stomach(8)|upper_aerodigestive_tract(16)|urinary_tract(7)	590						GGTAAGGACAACAGAGAAGAT	0.448000													9	30					0	0	1	0	0
PDE4DIP	9659	broad.mit.edu	37	1	144930870	144930870	+	Missense_Mutation	SNP	G	G	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr1:144930870G>A	ENST00000529945.1	-	1	1278	c.839C>T	c.(838-840)cCg>cTg	p.P280L	PDE4DIP_ENST00000369349.3_Intron|PDE4DIP_ENST00000369351.3_Intron|PDE4DIP_ENST00000369356.4_Intron|PDE4DIP_ENST00000369359.4_Intron|PDE4DIP_ENST00000479408.2_Intron|PDE4DIP_ENST00000313382.9_Intron|PDE4DIP_ENST00000369354.3_Intron|PDE4DIP_ENST00000313431.9_Missense_Mutation_p.P280L|PDE4DIP_ENST00000530740.1_Intron			Q5VU43	MYOME_HUMAN	phosphodiesterase 4D interacting protein	0					cellular protein complex assembly	centrosome|Golgi apparatus|myofibril|nucleus	enzyme binding			NS(1)|breast(3)|central_nervous_system(2)|cervix(2)|endometrium(15)|haematopoietic_and_lymphoid_tissue(2)|kidney(9)|large_intestine(12)|lung(106)|ovary(8)|prostate(7)|skin(3)|upper_aerodigestive_tract(4)|urinary_tract(2)	176				Colorectal(2;0.0829)|COAD - Colon adenocarcinoma(2;0.126)		CCCATGCTGCGGAGCCTGATC	0.498000			T	PDGFRB	MPD								7	135					0	0	1	0	0
DCDC1	341019	broad.mit.edu	37	11	30902775	30902775	+	Missense_Mutation	SNP	C	C	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr11:30902775C>A	ENST00000597505.1	-	35	5153	c.5154G>T	c.(5152-5154)caG>caT	p.Q1718H				P59894	DCDC1_HUMAN	doublecortin domain containing 1	224					intracellular signal transduction					central_nervous_system(1)|cervix(1)|endometrium(1)|kidney(2)|large_intestine(4)|lung(17)|pancreas(2)|prostate(1)|skin(1)|stomach(1)	31	Lung SC(675;0.225)					CGTCCCAGGACTGAATTGGCT	0.498000													3	37					0.115264	0.115264	1	1	0
SVEP1	79987	broad.mit.edu	37	9	113231326	113231326	+	Silent	SNP	G	G	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr9:113231326G>A	ENST00000401783.2	-	17	3390	c.3054C>T	c.(3052-3054)tgC>tgT	p.C1018C	SVEP1_ENST00000467821.1_5'UTR|SVEP1_ENST00000302728.8_Silent_p.C1018C|SVEP1_ENST00000374469.1_Silent_p.C995C	NM_153366.3	NP_699197.3	Q4LDE5	SVEP1_HUMAN	sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1	1018					cell adhesion	cytoplasm|extracellular region|membrane	calcium ion binding			NS(1)|autonomic_ganglia(1)|breast(5)|central_nervous_system(1)|cervix(2)|endometrium(19)|kidney(8)|large_intestine(24)|lung(58)|ovary(7)|prostate(7)|skin(1)|stomach(4)|upper_aerodigestive_tract(5)|urinary_tract(4)	147						ATCCGATCCGGCAGCTTTCAC	0.423000													3	47					0	0	1	0	0
THUMPD3	25917	broad.mit.edu	37	3	9426287	9426287	+	Missense_Mutation	SNP	A	A	G			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr3:9426287A>G	ENST00000345094.3	+	10	1773	c.1439A>G	c.(1438-1440)tAc>tGc	p.Y480C	THUMPD3_ENST00000452837.2_Missense_Mutation_p.Y480C|THUMPD3_ENST00000515662.2_Missense_Mutation_p.Y480C|SETD5-AS1_ENST00000468186.1_RNA	NM_001114092.1|NM_015453.2	NP_001107564.1|NP_056268.2	Q9BV44	THUM3_HUMAN	THUMP domain containing 3	480							methyltransferase activity|protein binding|RNA binding			NS(1)|central_nervous_system(1)|large_intestine(4)|lung(9)|ovary(1)|prostate(2)|upper_aerodigestive_tract(1)	19	Medulloblastoma(99;0.227)			OV - Ovarian serous cystadenocarcinoma(96;0.101)		GCTGCAGTTTACGTTCTGATA	0.433000													4	135					0	0	1	0	0
PCSK1	5122	broad.mit.edu	37	5	95728927	95728927	+	Silent	SNP	C	C	T			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr5:95728927C>T	ENST00000311106.3	-	14	2277	c.2040G>A	c.(2038-2040)ccG>ccA	p.P680P	PCSK1_ENST00000513085.1_5'UTR|PCSK1_ENST00000508626.1_Silent_p.P633P|CTD-2337A12.1_ENST00000502645.2_RNA	NM_000439.4|NM_001177876.1	NP_000430.3|NP_001171347.1	P29120	NEC1_HUMAN	proprotein convertase subtilisin/kexin type 1	680					cell-cell signaling|cellular nitrogen compound metabolic process|energy reserve metabolic process|hormone biosynthetic process|peptide biosynthetic process|peptide hormone processing|regulation of insulin secretion	extracellular space|stored secretory granule|transport vesicle	serine-type endopeptidase activity			NS(1)|endometrium(3)|kidney(3)|large_intestine(5)|lung(14)|ovary(2)|prostate(3)|skin(3)|urinary_tract(2)	36		all_cancers(142;2.67e-06)|all_epithelial(76;6.92e-09)|all_lung(232;0.00307)|Lung NSC(167;0.00452)|Ovarian(225;0.0112)|Colorectal(57;0.0341)|Breast(839;0.244)		all cancers(79;3.44e-16)	Insulin Glargine recombinant(DB00047)|Insulin Lyspro recombinant(DB00046)|Insulin recombinant(DB00030)|Insulin, porcine(DB00071)	ATTGCTTTGGCGGTGAGTTTT	0.532000													5	65					0	0	1	0	0
PSG8	0	broad.mit.edu	37	19	43258479	43258479	+	Missense_Mutation	SNP	G	G	A	rs146638942	by1000genomes	TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr19:43258479G>A	ENST00000306511.4	-	5	1346	c.1249C>T	c.(1249-1251)Cgg>Tgg	p.R417W	PSG8_ENST00000401467.2_Intron|PSG8_ENST00000600709.1_Intron|PSG8_ENST00000406636.3_Intron|PSG8_ENST00000404209.4_Intron	NM_182707.2	NP_874366.1	Q9UQ74	PSG8_HUMAN	pregnancy specific beta-1-glycoprotein 8	417						extracellular region				breast(1)|cervix(1)|endometrium(3)|kidney(2)|large_intestine(9)|lung(19)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	40		Prostate(69;0.00899)				ACTGGGATCCGCTTACCAGAG	0.478000													5	185					0	0	1	0	0
TCF4	6925	broad.mit.edu	37	18	52896292	52896292	+	Silent	SNP	C	C	T			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr18:52896292C>T	ENST00000354452.3	-	18	2276	c.1665G>A	c.(1663-1665)gaG>gaA	p.E555E	TCF4_ENST00000564999.1_Silent_p.E551E|TCF4_ENST00000540999.1_Silent_p.E527E|TCF4_ENST00000544241.2_Silent_p.E484E|TCF4_ENST00000537856.3_Silent_p.E421E|TCF4_ENST00000457482.3_Silent_p.E395E|TCF4_ENST00000564228.1_Silent_p.E480E|TCF4_ENST00000567880.1_Silent_p.E491E|TCF4_ENST00000356073.4_Silent_p.E551E|TCF4_ENST00000566279.1_Silent_p.E495E|TCF4_ENST00000543082.1_Silent_p.E509E|TCF4_ENST00000564403.2_Silent_p.E561E|TCF4_ENST00000561831.3_Silent_p.E391E|TCF4_ENST00000568673.1_Silent_p.E531E|TCF4_ENST00000565018.2_Silent_p.E555E|TCF4_ENST00000561992.1_Silent_p.E421E|TCF4_ENST00000398339.1_Silent_p.E657E|TCF4_ENST00000568740.1_Silent_p.E526E|TCF4_ENST00000537578.1_Silent_p.E531E|TCF4_ENST00000570287.2_Silent_p.E391E|TCF4_ENST00000570177.2_Silent_p.E421E|TCF4_ENST00000566286.1_Silent_p.E548E	NM_001083962.1	NP_001077431.1	P15884	ITF2_HUMAN	transcription factor 4	551					positive regulation of neuron differentiation|protein-DNA complex assembly|transcription initiation from RNA polymerase II promoter	transcription factor complex	E-box binding|protein C-terminus binding|protein heterodimerization activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|sequence-specific DNA binding RNA polymerase recruiting transcription factor activity|TFIIB-class binding transcription factor activity|TFIIB-class transcription factor binding			breast(1)|central_nervous_system(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(4)|lung(15)|ovary(1)|prostate(1)|skin(5)|urinary_tract(1)	41				Colorectal(16;0.00108)|READ - Rectum adenocarcinoma(59;0.0649)|COAD - Colon adenocarcinoma(17;0.0718)		GTGTCAGGTCCTCATCGTCAT	0.493000													4	93					0	0	1	0	0
DUSP27	92235	broad.mit.edu	37	1	167088583	167088583	+	Missense_Mutation	SNP	T	T	C			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr1:167088583T>C	ENST00000361200.2	+	5	701	c.535T>C	c.(535-537)Tac>Cac	p.Y179H	DUSP27_ENST00000271385.5_Missense_Mutation_p.Y179H|DUSP27_ENST00000443333.1_Missense_Mutation_p.Y179H			Q5VZP5	DUS27_HUMAN	dual specificity phosphatase 27 (putative)	179					protein dephosphorylation		protein tyrosine/serine/threonine phosphatase activity			NS(1)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(4)|kidney(2)|large_intestine(11)|liver(1)|lung(46)|ovary(5)|prostate(5)|skin(4)|upper_aerodigestive_tract(3)	89						CCCCGAATTCTACACTGGCCT	0.557000													5	36					0	0	1	0	0
GPR98	84059	broad.mit.edu	37	5	89990012	89990012	+	Nonsense_Mutation	SNP	G	G	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr5:89990012G>A	ENST00000405460.2	+	33	7535	c.7439G>A	c.(7438-7440)tGg>tAg	p.W2480*		NM_032119.3	NP_115495.3	Q8WXG9	GPR98_HUMAN	G protein-coupled receptor 98	2480					cell communication|cell-cell adhesion|maintenance of organ identity|neuropeptide signaling pathway|photoreceptor cell maintenance	cell surface|cytoplasm|integral to membrane|plasma membrane	calcium ion binding|G-protein coupled receptor activity			NS(4)|breast(7)|central_nervous_system(6)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(3)|kidney(18)|large_intestine(46)|liver(2)|lung(80)|ovary(12)|pancreas(5)|prostate(1)|skin(50)|stomach(7)|upper_aerodigestive_tract(8)|urinary_tract(6)	269		all_cancers(142;1.05e-09)|all_epithelial(76;1.81e-12)|all_lung(232;5.41e-06)|Lung NSC(167;1.72e-05)|Ovarian(174;0.00948)|Colorectal(57;0.133)|Breast(839;0.192)		OV - Ovarian serous cystadenocarcinoma(54;7.01e-30)|Epithelial(54;6.79e-25)|all cancers(79;1.88e-20)		TCAGACTTCTGGACCTACAGG	0.488000													3	28					0	0	1	0	0
ZNF609	23060	broad.mit.edu	37	15	64967480	64967480	+	Silent	SNP	C	C	T			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr15:64967480C>T	ENST00000326648.3	+	4	2555	c.2427C>T	c.(2425-2427)ggC>ggT	p.G809G		NM_015042.1	NP_055857.1	O15014	ZN609_HUMAN	zinc finger protein 609	809						nucleus	zinc ion binding			breast(3)|central_nervous_system(2)|endometrium(5)|kidney(1)|large_intestine(9)|lung(11)|ovary(1)|pancreas(1)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	39						CCATTGGAGGCAGTAGCCGCC	0.557000													4	67					0	0	1	0	0
SORCS1	114815	broad.mit.edu	37	10	108434877	108434877	+	Missense_Mutation	SNP	T	T	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr10:108434877T>A	ENST00000263054.6	-	14	1877	c.1870A>T	c.(1870-1872)Agt>Tgt	p.S624C	SORCS1_ENST00000344440.6_Missense_Mutation_p.S624C|SORCS1_ENST00000369698.1_Missense_Mutation_p.S159C	NM_001206570.1|NM_052918.4	NP_001193499.1|NP_443150.3	Q8WY21	SORC1_HUMAN	sortilin-related VPS10 domain containing receptor 1	624						integral to membrane	neuropeptide receptor activity|protein binding			breast(5)|central_nervous_system(1)|cervix(2)|endometrium(9)|kidney(2)|large_intestine(24)|lung(69)|ovary(1)|prostate(8)|skin(1)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	127		Breast(234;0.0256)|Colorectal(252;0.09)|Lung NSC(174;0.168)		Epithelial(162;1.66e-05)|all cancers(201;0.000689)		GATGTGAAACTGTATTTGCTC	0.388000													3	62					0	0	1	0	0
MUC16	94025	broad.mit.edu	37	19	9057380	9057380	+	Silent	SNP	A	A	T			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr19:9057380A>T	ENST00000397910.4	-	3	30269	c.30066T>A	c.(30064-30066)tcT>tcA	p.S10022S		NM_024690.2	NP_078966.2	Q8WXI7	MUC16_HUMAN	mucin 16, cell surface associated	10024	Ser-rich.|Thr-rich.				cell adhesion	extracellular space|extrinsic to membrane|integral to membrane|plasma membrane	protein binding			NS(9)|autonomic_ganglia(1)|breast(26)|central_nervous_system(11)|cervix(1)|endometrium(46)|haematopoietic_and_lymphoid_tissue(5)|kidney(35)|large_intestine(91)|liver(1)|lung(278)|ovary(17)|pancreas(2)|prostate(17)|skin(18)|soft_tissue(1)|stomach(8)|upper_aerodigestive_tract(16)|urinary_tract(7)	590						ACAACAGAGAAGATGAAGAGC	0.438000													9	29					0	0	1	0	0
CARD11	84433	broad.mit.edu	37	7	2953048	2953048	+	Silent	SNP	G	G	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr7:2953048G>A	ENST00000396946.4	-	22	3295	c.2892C>T	c.(2890-2892)agC>agT	p.S964S		NM_032415.4	NP_115791.3	Q9BXL7	CAR11_HUMAN	caspase recruitment domain family, member 11	964					positive regulation of cytokine production|positive regulation of NF-kappaB transcription factor activity|regulation of apoptosis|T cell costimulation|T cell receptor signaling pathway	cytosol|membrane raft|plasma membrane	CARD domain binding|guanylate kinase activity			NS(1)|breast(3)|central_nervous_system(1)|cervix(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(62)|kidney(11)|large_intestine(13)|lung(31)|ovary(4)|prostate(5)|skin(7)|upper_aerodigestive_tract(2)	150		Ovarian(82;0.0115)		OV - Ovarian serous cystadenocarcinoma(56;8.44e-14)		CGCGTACCAGGCTGTAGGGGA	0.677000			Mis		DLBCL								5	42					0	0	1	0	0
SIRPB2	284759	broad.mit.edu	37	20	1460495	1460495	+	Missense_Mutation	SNP	G	G	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr20:1460495G>A	ENST00000359801.3	-	2	337	c.301C>T	c.(301-303)Cgg>Tgg	p.R101W	SIRPB2_ENST00000537284.1_Intron|SIRPB2_ENST00000444444.1_Intron|SIRPB2_ENST00000381630.1_Intron	NM_001122962.1	NP_001116434.1	Q5JXA9	SIRB2_HUMAN	signal-regulatory protein beta 2	101	Ig-like V-type 1.					integral to membrane				endometrium(2)|kidney(2)|large_intestine(4)|lung(5)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	16						TCTGATGTCCGTTGGATCATG	0.448000													7	49					0	0	1	0	0
ANKRD20A8P	0	broad.mit.edu	37	2	95514945	95514945	+	RNA	SNP	C	C	T			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr2:95514945C>T	ENST00000432432.2	-	0	712					NR_040113.1																						AACTACTGTACCGTCTCAGCC	0.308000													4	204					0	0	1	0	0
OR8B8	26493	broad.mit.edu	37	11	124310141	124310141	+	Missense_Mutation	SNP	C	C	T			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr11:124310141C>T	ENST00000328064.2	-	1	913	c.841G>A	c.(841-843)Gtg>Atg	p.V281M		NM_012378.1	NP_036510.1	Q15620	OR8B8_HUMAN	olfactory receptor, family 8, subfamily B, member 8	281					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			cervix(1)|endometrium(4)|kidney(1)|large_intestine(5)|lung(15)|ovary(1)|skin(9)|upper_aerodigestive_tract(2)|urinary_tract(1)	39		Breast(109;0.0115)|Medulloblastoma(222;0.0523)|Lung NSC(97;0.118)|all_lung(97;0.126)|all_neural(223;0.224)		BRCA - Breast invasive adenocarcinoma(274;1.49e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0277)		ATGGGCACCACAGTGGTATAG	0.408000													8	77					0	0	1	0	0
RP11-526P5.2	0	broad.mit.edu	37	10	2561169	2561170	+	RNA	INS	-	-	G			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr10:2561169_2561170insG	ENST00000438753.1	+	0	207																											aagaagaagaagGGGGGGGGAG	0.386													3	3	---	---	---	---					
PDS5B	23047	broad.mit.edu	37	13	33344887	33344888	+	Frame_Shift_Ins	INS	-	-	A			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr13:33344887_33344888insA	ENST00000315596.10	+	33	4346_4347	c.4160_4161insA	c.(4159-4161)caafs	p.Q1387fs		NM_015032.3	NP_055847.1	Q9NTI5	PDS5B_HUMAN	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	1387					cell division|cell proliferation|mitotic sister chromatid cohesion|negative regulation of cell proliferation	chromatin|nucleus	ATP binding|DNA binding|identical protein binding	p.N1390fs*4(1)		NS(2)|breast(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(4)|kidney(5)|large_intestine(14)|lung(14)|ovary(5)|pancreas(1)|prostate(5)|skin(1)|upper_aerodigestive_tract(1)	62		Lung SC(185;0.0367)		all cancers(112;5.55e-06)|Epithelial(112;2.7e-05)|OV - Ovarian serous cystadenocarcinoma(117;0.00303)|BRCA - Breast invasive adenocarcinoma(63;0.0204)		CCATCACAACCAAAAAAAAATG	0.337													2	4	---	---	---	---					
RP11-1166P10.6	0	broad.mit.edu	37	16	32077919	32077920	+	RNA	INS	-	-	T	rs4026454	by1000genomes	TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chr16:32077919_32077920insT	ENST00000566806.1	-	0	499																											GAAAACGGTTATTTTTTTGTTC	0.426													2	4	---	---	---	---					
NHS	4810	broad.mit.edu	37	X	17750109	17750115	+	Frame_Shift_Del	DEL	CCAACAG	CCAACAG	-			TCGA-ZG-A9LU-01A-11D-A41K-08	TCGA-ZG-A9LU-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bbf7010e-343e-4a33-bf1f-91e5fa93eb6b	c3644dc8-4a3a-4db5-868a-ac65f2772be0	g.chrX:17750109_17750115delCCAACAG	ENST00000380060.3	+	8	4756_4762	c.4418_4424delCCAACAG	c.(4417-4425)ccfs	p.PNS1473fs	NHS_ENST00000398097.3_Frame_Shift_Del_p.PNS1317fs	NM_198270.2	NP_938011.1	Q6T4R5	NHS_HUMAN	Nance-Horan syndrome (congenital cataracts and dental anomalies)	1473						nucleus		p.P1317P(1)|p.P1473P(1)		breast(5)|central_nervous_system(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(17)|liver(1)|lung(26)|ovary(2)|prostate(1)|skin(3)|stomach(1)|upper_aerodigestive_tract(1)	71	Hepatocellular(33;0.183)					GTGACAACCCCCAACAGCCAGAGGTCT	0.507													9	56	---	---	---	---