Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
FCRLA	84824	broad.mit.edu	37	1	161683034	161683034	+	Missense_Mutation	SNP	C	C	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr1:161683034C>A	ENST00000540926.1	+	6	1255	c.962C>A	c.(961-963)cCt>cAt	p.P321H	FCRLA_ENST00000367950.1_Missense_Mutation_p.P108H|FCRLA_ENST00000546024.1_Missense_Mutation_p.P243H|FCRLA_ENST00000540521.1_Missense_Mutation_p.P198H|FCRLA_ENST00000367949.2_Missense_Mutation_p.P148H|FCRLA_ENST00000367953.3_Missense_Mutation_p.P321H|FCRLA_ENST00000367959.2_Missense_Mutation_p.P338H|FCRLA_ENST00000294796.4_Missense_Mutation_p.P181H|FCRLA_ENST00000470841.1_3'UTR|FCRLA_ENST00000349527.4_Missense_Mutation_p.P220H|FCRLA_ENST00000309691.6_Missense_Mutation_p.P226H|FCRLA_ENST00000236938.6_Missense_Mutation_p.P332H|FCRLA_ENST00000367957.2_Missense_Mutation_p.P192H|FCRLA_ENST00000350710.3_Missense_Mutation_p.P97H			Q7L513	FCRLA_HUMAN	Fc receptor-like A	315					cell differentiation	cytoplasm|extracellular region				breast(1)|kidney(12)|large_intestine(4)|lung(13)|prostate(1)|skin(2)|stomach(1)	34	all_cancers(52;2.55e-15)|all_hematologic(112;0.0359)		BRCA - Breast invasive adenocarcinoma(70;0.00301)			ATGCCAGATCCTCATCTGTAT	0.572000													3	53					0.00024832	0.000276538	0.150653	1	0
GPR128	84873	broad.mit.edu	37	3	100368589	100368589	+	Silent	SNP	C	C	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr3:100368589C>T	ENST00000273352.3	+	11	1585	c.1317C>T	c.(1315-1317)aaC>aaT	p.N439N	GPR128_ENST00000475887.1_Silent_p.N144N	NM_032787.2	NP_116176.2	Q96K78	GP128_HUMAN	G protein-coupled receptor 128	439					neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			NS(1)|autonomic_ganglia(1)|breast(2)|cervix(1)|endometrium(3)|kidney(2)|large_intestine(9)|liver(2)|lung(20)|ovary(3)|prostate(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(2)	56						TATTATCCAACGTTGGATGTG	0.373000													5	110					0	0	0.248553	0	0
SIRT1	23411	broad.mit.edu	37	10	69676124	69676124	+	Missense_Mutation	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr10:69676124G>A	ENST00000212015.6	+	9	2071	c.2018G>A	c.(2017-2019)aGt>aAt	p.S673N	SIRT1_ENST00000432464.1_Missense_Mutation_p.S378N|SIRT1_ENST00000406900.1_Missense_Mutation_p.S370N|SIRT1_ENST00000403579.1_Missense_Mutation_p.S370N	NM_012238.4	NP_036370.2	Q96EB6	SIRT1_HUMAN	sirtuin 1	673					apoptosis|cell aging|cellular response to hydrogen peroxide|cellular response to starvation|chromatin silencing at rDNA|DNA repair|DNA replication|establishment of chromatin silencing|histone H3 deacetylation|interspecies interaction between organisms|maintenance of chromatin silencing|muscle organ development|negative regulation of androgen receptor signaling pathway|negative regulation of cell growth|negative regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of fat cell differentiation|negative regulation of helicase activity|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription from RNA polymerase II promoter|peptidyl-lysine acetylation|peptidyl-lysine deacetylation|positive regulation of anti-apoptosis|positive regulation of chromatin silencing|positive regulation of DNA repair|regulation of apoptosis|regulation of cell proliferation|regulation of endodeoxyribonuclease activity|regulation of protein import into nucleus, translocation|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor|rRNA processing|transcription, DNA-dependent|triglyceride mobilization|white fat cell differentiation	chromatin silencing complex|cytoplasm|nuclear euchromatin|nuclear heterochromatin|nuclear inner membrane|nucleolus|PML body|rDNA heterochromatin	bHLH transcription factor binding|histone binding|HLH domain binding|identical protein binding|mitogen-activated protein kinase binding|NAD+ binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|p53 binding|protein C-terminus binding|transcription corepressor activity|zinc ion binding			central_nervous_system(1)|endometrium(1)|kidney(2)|large_intestine(6)|lung(3)|skin(1)	14						TCTTGTGGCAGTAACAGTGAT	0.413000													3	87					0	0	0.115264	0	0
AGPAT3	56894	broad.mit.edu	37	21	45379682	45379682	+	Silent	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr21:45379682G>A	ENST00000398063.2	+	2	612	c.120G>A	c.(118-120)ccG>ccA	p.P40P	AGPAT3_ENST00000398061.1_Silent_p.P40P|AGPAT3_ENST00000291572.8_Silent_p.P40P|AGPAT3_ENST00000546158.1_Silent_p.P40P|AGPAT3_ENST00000327505.2_Silent_p.P40P|AGPAT3_ENST00000479117.1_3'UTR|AGPAT3_ENST00000398058.1_Silent_p.P40P	NM_001037553.1	NP_001032642.1	Q9NRZ7	PLCC_HUMAN	1-acylglycerol-3-phosphate O-acyltransferase 3	40					phospholipid biosynthetic process	endoplasmic reticulum membrane|integral to membrane|plasma membrane	1-acylglycerol-3-phosphate O-acyltransferase activity			large_intestine(4)|lung(5)|ovary(1)|prostate(1)	11				STAD - Stomach adenocarcinoma(101;0.18)|Colorectal(79;0.24)		CGCTCTGGCCGGTCAGCAAGC	0.647000													4	59					0	0	0.150653	0	0
SLC15A1	6564	broad.mit.edu	37	13	99354751	99354751	+	Silent	SNP	T	T	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr13:99354751T>C	ENST00000376503.5	-	18	1504	c.1449A>G	c.(1447-1449)aaA>aaG	p.K483K		NM_005073.3	NP_005064.1	P46059	S15A1_HUMAN	solute carrier family 15 (oligopeptide transporter), member 1	483					digestion|protein transport	integral to plasma membrane|membrane fraction	peptide:hydrogen symporter activity			breast(1)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(3)|kidney(1)|large_intestine(6)|lung(10)|ovary(1)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	30	all_neural(89;0.101)|Medulloblastoma(90;0.18)|Lung SC(71;0.184)				Cefadroxil(DB01140)|Ceftibuten(DB01415)|Cyclacillin(DB01000)	CATTTTCCCCTTTTTCTGGCT	0.284000													3	152					0	0	0.184627	0	0
SUMO3	6612	broad.mit.edu	37	21	46233855	46233855	+	Silent	SNP	C	C	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr21:46233855C>T	ENST00000411651.2	-	2	298	c.186G>A	c.(184-186)gtG>gtA	p.V62V	SUMO3_ENST00000332859.6_Intron|SUMO3_ENST00000397893.3_Intron|SUMO3_ENST00000479153.1_Intron|SUMO3_ENST00000397898.3_Intron			P55854	SUMO3_HUMAN	small ubiquitin-like modifier 3	50	Ubiquitin-like.				protein sumoylation	cytoplasm|kinetochore	protein binding			prostate(1)	1				Colorectal(79;0.058)		CCAGTGCGCACACGGGGAGGC	0.652000													3	33					0	0	0.115264	0	0
CCDC132	55610	broad.mit.edu	37	7	92883177	92883177	+	Missense_Mutation	SNP	T	T	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr7:92883177T>G	ENST00000544910.1	+	5	360	c.140T>G	c.(139-141)cTt>cGt	p.L47R	CCDC132_ENST00000305866.5_Missense_Mutation_p.L77R|CCDC132_ENST00000535481.1_Intron|CCDC132_ENST00000317751.6_5'UTR|CCDC132_ENST00000541136.1_5'UTR|CCDC132_ENST00000251739.5_Missense_Mutation_p.L77R	NM_001257998.1	NP_001244927.1	Q96JG6	CC132_HUMAN	coiled-coil domain containing 132	77										endometrium(1)|large_intestine(2)|lung(5)	8	all_cancers(62;2.64e-11)|all_epithelial(64;1.4e-10)|Breast(17;0.000675)|Lung NSC(181;0.0618)|all_lung(186;0.0837)		STAD - Stomach adenocarcinoma(171;0.000302)			CTGTAGAAGCTTCCACCTGTT	0.338000													10	12					0	0	0.435327	0	0
CP	1356	broad.mit.edu	37	3	148924112	148924112	+	Missense_Mutation	SNP	A	A	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr3:148924112A>G	ENST00000264613.6	-	6	1313	c.1051T>C	c.(1051-1053)Ttt>Ctt	p.F351L		NM_000096.3	NP_000087.1	P00450	CERU_HUMAN	ceruloplasmin (ferroxidase)	351	F5/8 type A 1.|Plastocyanin-like 2.				cellular iron ion homeostasis|copper ion transport|transmembrane transport	extracellular space	chaperone binding|ferroxidase activity			breast(6)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(9)|lung(14)|ovary(1)|prostate(1)|soft_tissue(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	44		Prostate(884;0.00217)|Hepatocellular(537;0.00826)|Myeloproliferative disorder(1037;0.0122)|all_neural(597;0.0189)|Melanoma(1037;0.152)	LUSC - Lung squamous cell carcinoma(72;0.0473)|Lung(72;0.0607)		Drotrecogin alfa(DB00055)	ACCTGGAAAAAGGCTTGCAAA	0.433000													3	140					0	0	0.184627	0	0
SNCG	6623	broad.mit.edu	37	10	88718535	88718535	+	Silent	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr10:88718535G>A	ENST00000372017.3	+	1	123	c.81G>A	c.(79-81)acG>acA	p.T27T	SNCG_ENST00000348795.4_Silent_p.T27T	NM_003087.2	NP_003078.2	O76070	SYUG_HUMAN	synuclein, gamma (breast cancer-specific protein 1)	27	4 X 11 AA tandem repeats of [EGSA]-K-T-K- [EQ]-[GQ]-V-X(4).					microtubule organizing center|perinuclear region of cytoplasm|spindle	protein binding			endometrium(1)|skin(1)	2						AGGGGGTGACGGAAGCAGCTG	0.597000													3	69					0	0	0.217242	0	0
STK19	8859	broad.mit.edu	37	6	31946702	31946702	+	Missense_Mutation	SNP	A	A	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr6:31946702A>G	ENST00000375331.2	+	4	756	c.590A>G	c.(589-591)gAg>gGg	p.E197G	STK19_ENST00000463823.1_3'UTR|STK19_ENST00000375333.2_Missense_Mutation_p.E197G	NM_004197.1	NP_004188.1	P49842	STK19_HUMAN	serine/threonine kinase 19	197				QGE -> GQR (in Ref. 6; AAA99716).		nucleus	ATP binding|protein binding|protein serine/threonine kinase activity			skin(5)|upper_aerodigestive_tract(2)	7						GAGCAGGGGGAGATCAGAATC	0.532000													3	66					0	0	0.115264	0	0
TPST2	8459	broad.mit.edu	37	22	26937482	26937482	+	Missense_Mutation	SNP	G	G	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr22:26937482G>C	ENST00000338754.4	-	3	385	c.115C>G	c.(115-117)Cgg>Ggg	p.R39G	TPST2_ENST00000398110.2_Missense_Mutation_p.R39G|TPST2_ENST00000403880.1_Missense_Mutation_p.R39G	NM_003595.3	NP_003586.3	O60704	TPST2_HUMAN	tyrosylprotein sulfotransferase 2	39					peptidyl-tyrosine sulfation	endoplasmic reticulum|Golgi membrane|integral to membrane|membrane fraction	protein-tyrosine sulfotransferase activity			central_nervous_system(1)|large_intestine(1)|lung(5)	7						CGGGGGCTCCGCAGGCCCGCC	0.701000													3	41					0	0	0.115264	0	0
ELP5	23587	broad.mit.edu	37	17	7155834	7155834	+	Missense_Mutation	SNP	G	G	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr17:7155834G>C	ENST00000574993.1	+	1	230	c.13G>C	c.(13-15)Gag>Cag	p.E5Q	ELP5_ENST00000573657.1_Missense_Mutation_p.E5Q|ELP5_ENST00000354429.2_Missense_Mutation_p.E5Q|ELP5_ENST00000396627.2_Missense_Mutation_p.E5Q|RP1-4G17.5_ENST00000577138.1_Intron|ELP5_ENST00000356683.2_Missense_Mutation_p.E5Q|ELP5_ENST00000396628.2_Missense_Mutation_p.E5Q|ELP5_ENST00000574255.1_Missense_Mutation_p.E5Q					elongator acetyltransferase complex subunit 5																		GACGCCATCAGAGGGCGCCAG	0.627000													3	31					0	0	0.150653	0	0
CCDC15	80071	broad.mit.edu	37	11	124857495	124857495	+	Missense_Mutation	SNP	A	A	C	rs113451248		TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr11:124857495A>C	ENST00000529051.1	+	8	1632	c.1373A>C	c.(1372-1374)cAc>cCc	p.H458P	CCDC15_ENST00000344762.5_Missense_Mutation_p.H458P			Q0P6D6	CCD15_HUMAN	coiled-coil domain containing 15	458						centrosome				central_nervous_system(1)|cervix(1)|large_intestine(6)|lung(10)|ovary(1)|prostate(3)|skin(1)	23	all_hematologic(175;0.215)	Breast(109;0.00222)|Lung NSC(97;0.0177)|all_lung(97;0.0179)|Medulloblastoma(222;0.0425)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;1.68e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0413)		CATGTTCTCCACAAAGACCAA	0.418000													3	106					0	0	0.115264	0	0
LHX1	3975	broad.mit.edu	37	17	35297661	35297661	+	Missense_Mutation	SNP	A	A	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr17:35297661A>T	ENST00000254457.5	+	2	1656	c.245A>T	c.(244-246)aAa>aTa	p.K82I	RP11-445F12.2_ENST00000607336.1_RNA	NM_005568.3	NP_005559.2	P48742	LHX1_HUMAN	LIM homeobox 1	82	LIM zinc-binding 2.				cerebellar Purkinje cell differentiation|cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation|cervix development|comma-shaped body morphogenesis|dorsal/ventral pattern formation|ectoderm formation|embryonic pattern specification|embryonic retina morphogenesis in camera-type eye|embryonic viscerocranium morphogenesis|endoderm formation|forebrain regionalization|head development|motor axon guidance|negative regulation of transcription, DNA-dependent|nephric duct morphogenesis|nephron tubule epithelial cell differentiation|neuron migration|oviduct epithelium development|paramesonephric duct development|positive regulation of anterior head development|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of embryonic development|positive regulation of gastrulation|positive regulation of transcription, DNA-dependent|post-embryonic development|primitive streak formation|renal vesicle morphogenesis|retina layer formation|S-shaped body morphogenesis|spinal cord association neuron differentiation|transcription from RNA polymerase II promoter|ureteric bud development|uterine epithelium development|vagina development	nucleus|protein complex	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|zinc ion binding			NS(1)|central_nervous_system(1)|endometrium(3)|kidney(2)|large_intestine(1)|lung(5)|ovary(1)|prostate(1)|skin(1)	16		Breast(25;0.00607)				GCGCGGAGCAAAGTGTTTCAC	0.587000													3	21					0	0	0.115264	0	0
ATP1A2	477	broad.mit.edu	37	1	160098456	160098456	+	Silent	SNP	G	G	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr1:160098456G>C	ENST00000361216.3	+	9	1121	c.1032G>C	c.(1030-1032)ctG>ctC	p.L344L	ATP1A2_ENST00000392233.3_Silent_p.L344L|ATP1A2_ENST00000472488.1_3'UTR	NM_000702.3	NP_000693.1	P50993	AT1A2_HUMAN	ATPase, Na+/K+ transporting, alpha 2 polypeptide	344					ATP biosynthetic process		ATP binding|metal ion binding|sodium:potassium-exchanging ATPase activity			NS(1)|autonomic_ganglia(1)|breast(4)|central_nervous_system(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(13)|lung(30)|ovary(2)|skin(3)|upper_aerodigestive_tract(1)	69	all_cancers(52;1.11e-16)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.111)|LUSC - Lung squamous cell carcinoma(543;0.246)			GCCTGACCCTGACAGCCAAGC	0.572000													4	86					0	0	0.248553	0	0
TSHZ3	57616	broad.mit.edu	37	19	31770237	31770237	+	Silent	SNP	A	A	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr19:31770237A>G	ENST00000240587.4	-	2	789	c.462T>C	c.(460-462)agT>agC	p.S154S		NM_020856.2	NP_065907.2	Q63HK5	TSH3_HUMAN	teashirt zinc finger homeobox 3	154	Ser-rich.				negative regulation of transcription, DNA-dependent|regulation of respiratory gaseous exchange by neurological system process	growth cone|nucleus	chromatin binding|protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(4)|endometrium(15)|kidney(9)|large_intestine(20)|lung(60)|ovary(4)|pancreas(2)|prostate(4)|skin(5)	123	Esophageal squamous(110;0.226)					tgctgctgctactgctgctgc	0.607000													3	18					0	0	0.115264	0	0
FAT2	2196	broad.mit.edu	37	5	150922048	150922048	+	Silent	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr5:150922048G>A	ENST00000261800.5	-	9	8652	c.8640C>T	c.(8638-8640)caC>caT	p.H2880H		NM_001447.2	NP_001438.1	Q9NYQ8	FAT2_HUMAN	FAT atypical cadherin 2	2880	Cadherin 25.				epithelial cell migration|homophilic cell adhesion	cell-cell adherens junction|integral to membrane|nucleus	calcium ion binding			NS(6)|breast(3)|central_nervous_system(3)|cervix(5)|endometrium(15)|haematopoietic_and_lymphoid_tissue(4)|kidney(8)|large_intestine(61)|liver(1)|lung(60)|ovary(6)|prostate(5)|skin(5)|stomach(2)|upper_aerodigestive_tract(11)|urinary_tract(1)	196		Medulloblastoma(196;0.0912)|all_hematologic(541;0.104)	KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			TGGTCTGTCCGTGGTCATAGG	0.493000													4	144					0	0	0.184627	0	0
CTD-2620I22.1	0	broad.mit.edu	37	19	53472914	53472914	+	RNA	SNP	A	A	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr19:53472914A>G	ENST00000600068.1	-	0	489				ZNF702P_ENST00000270443.4_RNA																							TTTGATTTTCAATTAAAAACC	0.338000													4	27					0	0	0.150653	0	0
MT-ND5	4540	broad.mit.edu	37	MT	14132	14132	+	Missense_Mutation	SNP	T	T	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chrM:14132T>C	ENST00000361567.2	+	1	1796	c.1796T>C	c.(1795-1797)cTa>cCa	p.L599P				P03915	NU5M_HUMAN	mitochondrially encoded NADH dehydrogenase 5	599					mitochondrial electron transport, NADH to ubiquinone|transport	integral to membrane|mitochondrial respiratory chain complex I	NADH dehydrogenase (ubiquinone) activity			breast(4)|endometrium(29)|kidney(33)|pancreas(1)|prostate(7)	74					NADH(DB00157)	CATCCTAACCCTACTCCTAAT	0.398000													2	2					0	0	0.115264	0	0
ANK2	287	broad.mit.edu	37	4	114277273	114277273	+	Missense_Mutation	SNP	C	C	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr4:114277273C>T	ENST00000357077.4	+	38	7552	c.7499C>T	c.(7498-7500)aCg>aTg	p.T2500M	ANK2_ENST00000510275.2_Intron|ANK2_ENST00000394537.3_Intron|ANK2_ENST00000509550.1_Intron|ANK2_ENST00000506722.1_Intron|ANK2_ENST00000264366.6_Missense_Mutation_p.T2467M	NM_001148.4	NP_001139.3	Q01484	ANK2_HUMAN	ankyrin 2, neuronal	2467					axon guidance|signal transduction	apical plasma membrane|basolateral plasma membrane|cytoskeleton|cytosol|sarcomere	protein binding			NS(1)|biliary_tract(1)|breast(9)|central_nervous_system(10)|cervix(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(7)|large_intestine(54)|liver(2)|lung(112)|ovary(8)|pancreas(1)|prostate(7)|skin(11)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(10)	248		Ovarian(17;0.0448)|Hepatocellular(203;0.218)		OV - Ovarian serous cystadenocarcinoma(123;4.92e-05)		GAACTCTTGACGGAAGTGGCC	0.532000													13	91					0	0	0.435327	0	0
CASKIN1	57524	broad.mit.edu	37	16	2233835	2233835	+	Silent	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr16:2233835G>A	ENST00000343516.6	-	15	1616	c.1524C>T	c.(1522-1524)ccC>ccT	p.P508P	CASKIN1_ENST00000564289.1_Intron	NM_020764.3	NP_065815.1	Q8WXD9	CSKI1_HUMAN	CASK interacting protein 1	508	SAM 1.				signal transduction	cytoplasm				breast(1)|central_nervous_system(1)|cervix(1)|endometrium(3)|kidney(2)|liver(1)|lung(7)|ovary(4)|prostate(5)|skin(3)	28						AGCTCACCTCGGGAGTCATGC	0.667000													3	86					0	0	0.150653	0	0
ANKAR	150709	broad.mit.edu	37	2	190584454	190584454	+	Missense_Mutation	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr2:190584454G>A	ENST00000520309.1	+	11	2469	c.2381G>A	c.(2380-2382)tGt>tAt	p.C794Y	ANKAR_ENST00000431575.2_Missense_Mutation_p.C723Y|ANKAR_ENST00000438402.2_Missense_Mutation_p.C794Y|ANKAR_ENST00000281412.6_Missense_Mutation_p.C558Y|ANKAR_ENST00000313581.4_Missense_Mutation_p.C794Y	NM_144708.3	NP_653309.3	Q7Z5J8	ANKAR_HUMAN	ankyrin and armadillo repeat containing	794						integral to membrane	binding			breast(3)|central_nervous_system(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(7)|liver(2)|lung(16)|ovary(2)|pancreas(1)|skin(1)|urinary_tract(2)	46			OV - Ovarian serous cystadenocarcinoma(117;0.00156)|Epithelial(96;0.0256)|all cancers(119;0.0744)			CTACTGGTTTGTGATGAGCCT	0.398000													23	41					0	0	0.654019	0	0
ARHGEF10L	55160	broad.mit.edu	37	1	17953976	17953976	+	Missense_Mutation	SNP	G	G	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr1:17953976G>T	ENST00000361221.3	+	15	1721	c.1562G>T	c.(1561-1563)aGt>aTt	p.S521I	ARHGEF10L_ENST00000167825.4_Missense_Mutation_p.S229I|ARHGEF10L_ENST00000434513.1_Missense_Mutation_p.S521I|ARHGEF10L_ENST00000452522.1_Missense_Mutation_p.S482I|ARHGEF10L_ENST00000375420.3_Missense_Mutation_p.S279I|ARHGEF10L_ENST00000375415.1_Missense_Mutation_p.S482I|ARHGEF10L_ENST00000469726.1_3'UTR|ARHGEF10L_ENST00000375408.3_Missense_Mutation_p.S299I	NM_018125.3	NP_060595.3	Q9HCE6	ARGAL_HUMAN	Rho guanine nucleotide exchange factor (GEF) 10-like	521					regulation of Rho protein signal transduction	cytoplasm	Rho guanyl-nucleotide exchange factor activity			NS(1)|breast(1)|central_nervous_system(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(5)|liver(2)|lung(16)|ovary(4)|pancreas(1)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)	43		Colorectal(325;3.46e-05)|Breast(348;0.000162)|all_lung(284;0.000337)|Lung NSC(340;0.000419)|Renal(390;0.000518)|Ovarian(437;0.00409)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00598)|COAD - Colon adenocarcinoma(227;1.62e-05)|BRCA - Breast invasive adenocarcinoma(304;1.68e-05)|Kidney(64;0.000269)|KIRC - Kidney renal clear cell carcinoma(64;0.00361)|STAD - Stomach adenocarcinoma(196;0.00656)|READ - Rectum adenocarcinoma(331;0.0718)|Lung(427;0.204)		AAGAGCGTCAGTGACCGCAGC	0.667000													3	29					0.00024832	0.000276538	0.150653	1	0
LENG8	114823	broad.mit.edu	37	19	54969308	54969308	+	Missense_Mutation	SNP	C	C	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr19:54969308C>G	ENST00000326764.5	+	14	2408	c.1929C>G	c.(1927-1929)tgC>tgG	p.C643W	LENG8_ENST00000376514.2_Intron	NM_052925.2	NP_443157.1	Q96PV6	LENG8_HUMAN	leukocyte receptor cluster (LRC) member 8	606							protein binding			breast(1)|central_nervous_system(3)|endometrium(3)|kidney(1)|large_intestine(6)|lung(9)|pancreas(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	30	Ovarian(34;0.19)			GBM - Glioblastoma multiforme(193;0.139)		TTAACCAGTGCCAGACGCAGC	0.572000													13	123					0	0	0.557998	0	0
SGK3	23678	broad.mit.edu	37	8	67705990	67705990	+	Missense_Mutation	SNP	A	A	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr8:67705990A>G	ENST00000396596.1	+	2	233	c.19A>G	c.(19-21)Atg>Gtg	p.M7V	SGK3_ENST00000521198.2_Missense_Mutation_p.M7V|SGK3_ENST00000345714.4_Missense_Mutation_p.M7V|C8orf44-SGK3_ENST00000520044.1_3'UTR|SGK3_ENST00000520976.1_Missense_Mutation_p.M7V|SGK3_ENST00000522398.1_Missense_Mutation_p.M7V|C8orf44-SGK3_ENST00000519289.1_Missense_Mutation_p.M7V	NM_013257.4	NP_037389.4	Q96BR1	SGK3_HUMAN	serum/glucocorticoid regulated kinase family, member 3	7					cell communication|response to stress	cytoplasmic membrane-bounded vesicle|early endosome	ATP binding|phosphatidylinositol binding|protein serine/threonine kinase activity			breast(1)|endometrium(2)|kidney(2)|large_intestine(2)|lung(9)|ovary(1)|upper_aerodigestive_tract(1)	18	Breast(64;0.186)	Lung NSC(129;0.0908)|all_lung(136;0.152)	Epithelial(68;0.0046)|OV - Ovarian serous cystadenocarcinoma(28;0.0112)|all cancers(69;0.0141)|BRCA - Breast invasive adenocarcinoma(89;0.206)			AGATCACACCATGGACTACAA	0.403000													16	27					0	0	0.608945	0	0
SCNN1G	6340	broad.mit.edu	37	16	23200962	23200962	+	Missense_Mutation	SNP	C	C	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr16:23200962C>G	ENST00000300061.2	+	3	731	c.588C>G	c.(586-588)atC>atG	p.I196M		NM_001039.3	NP_001030.2	P51170	SCNNG_HUMAN	sodium channel, non-voltage-gated 1, gamma subunit	196					excretion|sensory perception of taste	apical plasma membrane|integral to plasma membrane	ligand-gated sodium channel activity|WW domain binding			NS(2)|autonomic_ganglia(1)|breast(1)|cervix(2)|kidney(1)|large_intestine(9)|lung(9)|ovary(2)|pancreas(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)	34				GBM - Glioblastoma multiforme(48;0.0366)	Amiloride(DB00594)|Triamterene(DB00384)	TCATGCACATCGAGTCCAAGC	0.517000													5	284					0	0	0.217242	0	0
ANGPTL5	253935	broad.mit.edu	37	11	101775573	101775573	+	Silent	SNP	A	A	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr11:101775573A>G	ENST00000334289.3	-	5	1006	c.411T>C	c.(409-411)ccT>ccC	p.P137P		NM_178127.4	NP_835228.2	Q86XS5	ANGL5_HUMAN	angiopoietin-like 5	137					signal transduction	extracellular space	receptor binding			breast(1)|endometrium(1)|kidney(2)|large_intestine(10)|lung(10)|ovary(2)|skin(3)	29		Acute lymphoblastic leukemia(157;0.000966)|all_hematologic(158;0.043)		BRCA - Breast invasive adenocarcinoma(274;0.0328)		TGTGAGGAAAAGGATCCAGCT	0.358000													3	72					0	0	0.184627	0	0
CELSR1	9620	broad.mit.edu	37	22	46785281	46785281	+	Missense_Mutation	SNP	C	C	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr22:46785281C>A	ENST00000262738.3	-	18	6460	c.6461G>T	c.(6460-6462)cGc>cTc	p.R2154L		NM_014246.1	NP_055061.1	Q9NYQ6	CELR1_HUMAN	cadherin, EGF LAG seven-pass G-type receptor 1	2154					central nervous system development|homophilic cell adhesion|neural tube closure|neuropeptide signaling pathway	integral to plasma membrane	calcium ion binding|G-protein coupled receptor activity|protein dimerization activity			breast(8)|central_nervous_system(5)|cervix(1)|endometrium(15)|haematopoietic_and_lymphoid_tissue(5)|kidney(4)|large_intestine(13)|lung(27)|ovary(2)|pancreas(2)|prostate(3)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(3)	95		Ovarian(80;0.00142)|Breast(42;0.00296)|all_neural(38;0.0416)|Colorectal(5;0.0766)		UCEC - Uterine corpus endometrioid carcinoma (28;0.00643)|BRCA - Breast invasive adenocarcinoma(115;0.171)		GTAGGCCGTGCGCACGTCATT	0.672000													3	38					0.115264	0.120169	0.115264	1	0
SEMA3A	10371	broad.mit.edu	37	7	83640389	83640389	+	Missense_Mutation	SNP	T	T	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr7:83640389T>G	ENST00000265362.3	-	9	1258	c.944A>C	c.(943-945)aAc>aCc	p.N315T	SEMA3A_ENST00000436949.1_Missense_Mutation_p.N315T	NM_006080.2	NP_006071.1	Q14563	SEM3A_HUMAN	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	315	Sema.				axon guidance	extracellular region|membrane	receptor activity			breast(3)|cervix(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(12)|liver(1)|lung(22)|ovary(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	53						ATCTTTAAAGTTCATTAGGAA	0.299000													6	44					0	0	0.217242	0	0
TSHZ3	57616	broad.mit.edu	37	19	31770234	31770234	+	Silent	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr19:31770234G>A	ENST00000240587.4	-	2	792	c.465C>T	c.(463-465)agC>agT	p.S155S		NM_020856.2	NP_065907.2	Q63HK5	TSH3_HUMAN	teashirt zinc finger homeobox 3	155	Ser-rich.				negative regulation of transcription, DNA-dependent|regulation of respiratory gaseous exchange by neurological system process	growth cone|nucleus	chromatin binding|protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding	p.S155S(1)		breast(4)|endometrium(15)|kidney(9)|large_intestine(20)|lung(60)|ovary(4)|pancreas(2)|prostate(4)|skin(5)	123	Esophageal squamous(110;0.226)					tgctgctgctgctactgctgc	0.612000													3	17					0	0	0.115264	0	0
CD209	30835	broad.mit.edu	37	19	7810767	7810767	+	Missense_Mutation	SNP	G	G	A	rs146082308		TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr19:7810767G>A	ENST00000315599.7	-	4	407	c.385C>T	c.(385-387)Cgg>Tgg	p.R129W	CD209_ENST00000602261.1_Missense_Mutation_p.R129W|CD209_ENST00000315591.8_Missense_Mutation_p.R105W|CD209_ENST00000601951.1_Missense_Mutation_p.R105W|CD209_ENST00000301357.8_Missense_Mutation_p.R85W|CD209_ENST00000601256.1_Missense_Mutation_p.R105W|CD209_ENST00000593821.1_Missense_Mutation_p.R85W|CD209_ENST00000593660.1_Missense_Mutation_p.R105W|CD209_ENST00000394173.4_Intron|CD209_ENST00000394161.5_Intron|CD209_ENST00000354397.6_Missense_Mutation_p.R129W|CD209_ENST00000204801.8_Missense_Mutation_p.R85W	NM_001144895.1|NM_001144897.1|NM_021155.3	NP_001138367.1|NP_001138369.1|NP_066978.1	Q9NNX6	CD209_HUMAN	CD209 molecule	129	7 X approximate tandem repeats.				cell-cell recognition|endocytosis|heterophilic cell-cell adhesion|innate immune response|intracellular signal transduction|intracellular virion transport|leukocyte cell-cell adhesion|peptide antigen transport|viral genome replication|virion attachment to host cell surface receptor	cytoplasm|extracellular region|integral to membrane|plasma membrane	mannose binding|metal ion binding|peptide antigen binding|receptor activity|virion binding	p.R129W(4)		endometrium(7)|kidney(3)|large_intestine(6)|lung(10)|ovary(1)|prostate(1)|skin(5)|upper_aerodigestive_tract(1)|urinary_tract(1)	35						GCCTTCAGCCGGGTCAGCTCC	0.567000													5	200					0	0	0.217242	0	0
LRFN5	145581	broad.mit.edu	37	14	42356070	42356070	+	Missense_Mutation	SNP	C	C	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr14:42356070C>A	ENST00000554171.1	+	5	2674	c.242C>A	c.(241-243)aCt>aAt	p.T81N	LRFN5_ENST00000554120.1_Missense_Mutation_p.T81N|LRFN5_ENST00000298119.4_Missense_Mutation_p.T81N			Q96NI6	LRFN5_HUMAN	leucine rich repeat and fibronectin type III domain containing 5	81						integral to membrane				breast(1)|central_nervous_system(1)|cervix(1)|endometrium(3)|kidney(4)|large_intestine(12)|liver(1)|lung(67)|ovary(5)|pancreas(3)|prostate(1)|skin(9)|stomach(1)|upper_aerodigestive_tract(9)|urinary_tract(2)	120			LUAD - Lung adenocarcinoma(50;0.0223)|Lung(238;0.0728)	GBM - Glioblastoma multiforme(112;0.00847)		GTGGACCTGACTCTATCCAGG	0.373000										HNSCC(30;0.082)			27	36					5.45727e-16	6.36681e-16	0.729181	1	0
XIST	0	broad.mit.edu	37	X	73066504	73066504	+	RNA	SNP	A	A	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chrX:73066504A>T	ENST00000429829.1	-	0	6084					NR_001564.2																						GGAAGGGAAAAGTGGGGATGA	0.478000													4	19					0	0	0.217242	0	0
ANKAR	150709	broad.mit.edu	37	2	190557050	190557050	+	Missense_Mutation	SNP	T	T	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr2:190557050T>C	ENST00000520309.1	+	4	1197	c.1109T>C	c.(1108-1110)tTt>tCt	p.F370S	ANKAR_ENST00000313581.4_Missense_Mutation_p.F370S|ANKAR_ENST00000431575.2_Missense_Mutation_p.F299S|ANKAR_ENST00000461516.1_Intron|ANKAR_ENST00000438402.2_Missense_Mutation_p.F370S|ANKAR_ENST00000281412.6_Missense_Mutation_p.F134S	NM_144708.3	NP_653309.3	Q7Z5J8	ANKAR_HUMAN	ankyrin and armadillo repeat containing	370						integral to membrane	binding			breast(3)|central_nervous_system(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(7)|liver(2)|lung(16)|ovary(2)|pancreas(1)|skin(1)|urinary_tract(2)	46			OV - Ovarian serous cystadenocarcinoma(117;0.00156)|Epithelial(96;0.0256)|all cancers(119;0.0744)			TGCCAGAATTTTCACTACAAA	0.318000													9	40					0	0	0.361761	0	0
GALNT10	55568	broad.mit.edu	37	5	153760070	153760070	+	Missense_Mutation	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr5:153760070G>A	ENST00000297107.6	+	6	954	c.817G>A	c.(817-819)Gac>Aac	p.D273N	SAP30L-AS1_ENST00000519727.1_RNA|GALNT10_ENST00000377661.2_Missense_Mutation_p.D211N|GALNT10_ENST00000425427.2_Missense_Mutation_p.D273N|GALNT10_ENST00000519544.1_3'UTR	NM_198321.3	NP_938080.1	Q86SR1	GLT10_HUMAN	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)	273						Golgi membrane|integral to membrane	metal ion binding|polypeptide N-acetylgalactosaminyltransferase activity|sugar binding			cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(7)|lung(12)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)	32	Renal(175;0.00488)	Medulloblastoma(196;0.0354)|all_neural(177;0.147)|all_hematologic(541;0.21)	Kidney(363;8.21e-05)|KIRC - Kidney renal clear cell carcinoma(527;0.000577)			TGACCATGACGACTTTCGGTA	0.532000													17	185					0	0	0.575678	0	0
RNF43	54894	broad.mit.edu	37	17	56434877	56434877	+	Missense_Mutation	SNP	C	C	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr17:56434877C>G	ENST00000584437.1	-	8	4215	c.2260G>C	c.(2260-2262)Ggc>Cgc	p.G754R	BZRAP1-AS1_ENST00000583841.1_RNA|RNF43_ENST00000581868.1_Missense_Mutation_p.G627R|RNF43_ENST00000577625.1_Missense_Mutation_p.G627R|RNF43_ENST00000583753.1_Missense_Mutation_p.G713R|RNF43_ENST00000577716.1_Missense_Mutation_p.G754R|RNF43_ENST00000500597.2_Missense_Mutation_p.G713R|RNF43_ENST00000407977.2_Missense_Mutation_p.G754R			Q68DV7	RNF43_HUMAN	ring finger protein 43	754	Pro-rich.					endoplasmic reticulum membrane|integral to membrane|nuclear envelope	ligase activity|protein binding|zinc ion binding			NS(1)|biliary_tract(5)|breast(1)|central_nervous_system(1)|endometrium(10)|kidney(2)|large_intestine(14)|lung(9)|ovary(2)|pancreas(10)|prostate(1)|skin(4)	60	Medulloblastoma(34;0.127)|all_neural(34;0.237)					CATGGCCTGCCCTCTGCGGTG	0.597000													16	99					0	0	0.539581	0	0
ARMS2	387715	broad.mit.edu	37	10	124214267	124214267	+	Silent	SNP	G	G	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr10:124214267G>T	ENST00000528446.1	+	1	99	c.24G>T	c.(22-24)ccG>ccT	p.P8P		NM_001099667.1	NP_001093137.1	P0C7Q2	ARMS2_HUMAN	age-related maculopathy susceptibility 2	8					retina homeostasis	mitochondrion|photoreceptor inner segment				ovary(1)	1		all_neural(114;0.0765)|Lung NSC(174;0.132)|all_lung(145;0.163)|Breast(234;0.238)				ACCCAGGACCGATGGTAACTG	0.572000													3	109					0.115264	0.120169	0.115264	1	0
CSPG4	1464	broad.mit.edu	37	15	75982728	75982728	+	Silent	SNP	T	T	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr15:75982728T>C	ENST00000308508.5	-	3	770	c.678A>G	c.(676-678)ctA>ctG	p.L226L		NM_001897.4	NP_001888.2	Q6UVK1	CSPG4_HUMAN	chondroitin sulfate proteoglycan 4	226	Globular or compact configuration stabilized by disulfide bonds.|Laminin G-like 2.|Neurite growth inhibition (By similarity).				angiogenesis|cell differentiation|intracellular signal transduction|positive regulation of peptidyl-tyrosine phosphorylation|tissue remodeling	apical plasma membrane|cell surface|integral to plasma membrane|intracellular|lamellipodium membrane	protein kinase binding|signal transducer activity			breast(1)|cervix(2)|endometrium(5)|kidney(5)|large_intestine(3)|liver(2)|lung(18)|ovary(2)|pancreas(2)|prostate(4)|skin(4)	48						GTGTAAACTCTAGGGTTCCTT	0.607000													3	24					0	0	0.184627	0	0
PTPRA	0	broad.mit.edu	37	20	2988040	2988040	+	Missense_Mutation	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr20:2988040G>A	ENST00000216877.6	+	10	1253	c.853G>A	c.(853-855)Gat>Aat	p.D285N	PTPRA_ENST00000399903.2_Missense_Mutation_p.D294N|PTPRA_ENST00000358719.4_Missense_Mutation_p.D150N|PTPRA_ENST00000380393.3_Missense_Mutation_p.D294N|PTPRA_ENST00000425918.2_Missense_Mutation_p.D305N|PTPRA_ENST00000318266.5_Missense_Mutation_p.D285N|PTPRA_ENST00000356147.3_Missense_Mutation_p.D285N	NM_080840.2	NP_543030.1	P18433	PTPRA_HUMAN	protein tyrosine phosphatase, receptor type, A	294	Tyrosine-protein phosphatase 1.				axon guidance|protein phosphorylation	integral to plasma membrane	transmembrane receptor protein tyrosine phosphatase activity			NS(1)|breast(1)|endometrium(3)|large_intestine(3)|lung(5)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	17						TCCAGATTCTGATTACATCAA	0.448000													48	95					0	0	0.870114	0	0
SERPINA6	866	broad.mit.edu	37	14	94780979	94780979	+	Missense_Mutation	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr14:94780979G>A	ENST00000341584.3	-	2	153	c.7C>T	c.(7-9)Ctc>Ttc	p.L3F		NM_001756.3	NP_001747.2	P08185	CBG_HUMAN	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	3					regulation of proteolysis|transport	extracellular space	serine-type endopeptidase inhibitor activity|steroid binding			central_nervous_system(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(11)|ovary(1)|skin(4)|upper_aerodigestive_tract(1)	26		all_cancers(154;0.0482)|all_epithelial(191;0.166)		COAD - Colon adenocarcinoma(157;0.211)	Alclometasone(DB00240)|Beclomethasone(DB00394)|Ciclesonide(DB01410)|Flumethasone Pivalate(DB00663)|Flunisolide(DB00180)|Fluocinolone Acetonide(DB00591)|Fluocinonide(DB01047)|Fluorometholone(DB00324)|Flurandrenolide(DB00846)|Fluticasone Propionate(DB00588)|Halobetasol Propionate(DB00596)|Medrysone(DB00253)|Mitotane(DB00648)|Paramethasone(DB01384)|Prednisolone(DB00860)|Rimexolone(DB00896)|Triamcinolone(DB00620)	TACAGGAGGAGTGGCATTGTC	0.547000													14	101					0	0	0.539581	0	0
FCRLA	84824	broad.mit.edu	37	1	161683034	161683034	+	Missense_Mutation	SNP	C	C	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr1:161683034C>A	ENST00000367959.2	+	6	1255	c.1013C>A	c.(1012-1014)cCt>cAt	p.P338H	FCRLA_ENST00000349527.4_Missense_Mutation_p.P220H|FCRLA_ENST00000367953.3_Missense_Mutation_p.P321H|FCRLA_ENST00000309691.6_Missense_Mutation_p.P226H|FCRLA_ENST00000367957.2_Missense_Mutation_p.P192H|FCRLA_ENST00000294796.4_Missense_Mutation_p.P181H|FCRLA_ENST00000540926.1_Missense_Mutation_p.P321H|FCRLA_ENST00000546024.1_Missense_Mutation_p.P243H|FCRLA_ENST00000540521.1_Missense_Mutation_p.P198H|FCRLA_ENST00000236938.6_Missense_Mutation_p.P332H|FCRLA_ENST00000367949.2_Missense_Mutation_p.P148H|FCRLA_ENST00000367950.1_Missense_Mutation_p.P108H|FCRLA_ENST00000350710.3_Missense_Mutation_p.P97H|FCRLA_ENST00000470841.1_3'UTR	NM_001184866.1	NP_001171795.1	Q7L513	FCRLA_HUMAN	Fc receptor-like A	315					cell differentiation	cytoplasm|extracellular region				breast(1)|kidney(12)|large_intestine(4)|lung(13)|prostate(1)|skin(2)|stomach(1)	34	all_cancers(52;2.55e-15)|all_hematologic(112;0.0359)		BRCA - Breast invasive adenocarcinoma(70;0.00301)			ATGCCAGATCCTCATCTGTAT	0.572000													3	53					0.00024832	0.000274737	0.150653	1	0
GPR128	84873	broad.mit.edu	37	3	100368589	100368589	+	Silent	SNP	C	C	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr3:100368589C>T	ENST00000273352.3	+	11	1585	c.1317C>T	c.(1315-1317)aaC>aaT	p.N439N	GPR128_ENST00000475887.1_Silent_p.N144N	NM_032787.2	NP_116176.2	Q96K78	GP128_HUMAN	G protein-coupled receptor 128	439					neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			NS(1)|autonomic_ganglia(1)|breast(2)|cervix(1)|endometrium(3)|kidney(2)|large_intestine(9)|liver(2)|lung(20)|ovary(3)|prostate(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(2)	56						TATTATCCAACGTTGGATGTG	0.373000													5	110					0	0	0.248553	0	0
HLA-DQB2	3120	broad.mit.edu	37	6	32725567	32725567	+	Missense_Mutation	SNP	C	C	T	rs114234640	byFrequency	TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr6:32725567C>T	ENST00000435145.2	-	4	801	c.740G>A	c.(739-741)cGt>cAt	p.R247H	HLA-DQB2_ENST00000411527.1_Intron|HLA-DQB2_ENST00000437316.2_Missense_Mutation_p.R247H			Q5SR06	Q5SR06_HUMAN	major histocompatibility complex, class II, DQ beta 2	216					antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|immune response	integral to membrane|MHC class II protein complex				endometrium(1)|kidney(1)|lung(1)|prostate(2)	5						ACCCCTGTGACGGATGATAAG	0.552000													7	26					0	0	0.361761	0	0
SIRT1	23411	broad.mit.edu	37	10	69676124	69676124	+	Missense_Mutation	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr10:69676124G>A	ENST00000212015.6	+	9	2071	c.2018G>A	c.(2017-2019)aGt>aAt	p.S673N	SIRT1_ENST00000403579.1_Missense_Mutation_p.S370N|SIRT1_ENST00000406900.1_Missense_Mutation_p.S370N|SIRT1_ENST00000432464.1_Missense_Mutation_p.S378N	NM_012238.4	NP_036370.2	Q96EB6	SIRT1_HUMAN	sirtuin 1	673					apoptosis|cell aging|cellular response to hydrogen peroxide|cellular response to starvation|chromatin silencing at rDNA|DNA repair|DNA replication|establishment of chromatin silencing|histone H3 deacetylation|interspecies interaction between organisms|maintenance of chromatin silencing|muscle organ development|negative regulation of androgen receptor signaling pathway|negative regulation of cell growth|negative regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of fat cell differentiation|negative regulation of helicase activity|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription from RNA polymerase II promoter|peptidyl-lysine acetylation|peptidyl-lysine deacetylation|positive regulation of anti-apoptosis|positive regulation of chromatin silencing|positive regulation of DNA repair|regulation of apoptosis|regulation of cell proliferation|regulation of endodeoxyribonuclease activity|regulation of protein import into nucleus, translocation|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor|rRNA processing|transcription, DNA-dependent|triglyceride mobilization|white fat cell differentiation	chromatin silencing complex|cytoplasm|nuclear euchromatin|nuclear heterochromatin|nuclear inner membrane|nucleolus|PML body|rDNA heterochromatin	bHLH transcription factor binding|histone binding|HLH domain binding|identical protein binding|mitogen-activated protein kinase binding|NAD+ binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|p53 binding|protein C-terminus binding|transcription corepressor activity|zinc ion binding			central_nervous_system(1)|endometrium(1)|kidney(2)|large_intestine(6)|lung(3)|skin(1)	14						TCTTGTGGCAGTAACAGTGAT	0.413000													3	87					0	0	0.115264	0	0
AGPAT3	56894	broad.mit.edu	37	21	45379682	45379682	+	Silent	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr21:45379682G>A	ENST00000398063.2	+	2	612	c.120G>A	c.(118-120)ccG>ccA	p.P40P	AGPAT3_ENST00000327505.2_Silent_p.P40P|AGPAT3_ENST00000291572.8_Silent_p.P40P|AGPAT3_ENST00000398058.1_Silent_p.P40P|AGPAT3_ENST00000546158.1_Silent_p.P40P|AGPAT3_ENST00000398061.1_Silent_p.P40P|AGPAT3_ENST00000479117.1_3'UTR	NM_001037553.1	NP_001032642.1	Q9NRZ7	PLCC_HUMAN	1-acylglycerol-3-phosphate O-acyltransferase 3	40					phospholipid biosynthetic process	endoplasmic reticulum membrane|integral to membrane|plasma membrane	1-acylglycerol-3-phosphate O-acyltransferase activity			large_intestine(4)|lung(5)|ovary(1)|prostate(1)	11				STAD - Stomach adenocarcinoma(101;0.18)|Colorectal(79;0.24)		CGCTCTGGCCGGTCAGCAAGC	0.647000													4	59					0	0	0.150653	0	0
SLC15A1	6564	broad.mit.edu	37	13	99354751	99354751	+	Silent	SNP	T	T	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr13:99354751T>C	ENST00000376503.5	-	18	1504	c.1449A>G	c.(1447-1449)aaA>aaG	p.K483K		NM_005073.3	NP_005064.1	P46059	S15A1_HUMAN	solute carrier family 15 (oligopeptide transporter), member 1	483					digestion|protein transport	integral to plasma membrane|membrane fraction	peptide:hydrogen symporter activity			breast(1)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(3)|kidney(1)|large_intestine(6)|lung(10)|ovary(1)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	30	all_neural(89;0.101)|Medulloblastoma(90;0.18)|Lung SC(71;0.184)				Cefadroxil(DB01140)|Ceftibuten(DB01415)|Cyclacillin(DB01000)	CATTTTCCCCTTTTTCTGGCT	0.284000													3	152					0	0	0.184627	0	0
SUMO3	6612	broad.mit.edu	37	21	46233855	46233855	+	Silent	SNP	C	C	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr21:46233855C>T	ENST00000411651.2	-	2	298	c.186G>A	c.(184-186)gtG>gtA	p.V62V	SUMO3_ENST00000332859.6_Intron|SUMO3_ENST00000397898.3_Intron|SUMO3_ENST00000397893.3_Intron|SUMO3_ENST00000479153.1_Intron			P55854	SUMO3_HUMAN	small ubiquitin-like modifier 3	50	Ubiquitin-like.				protein sumoylation	cytoplasm|kinetochore	protein binding			prostate(1)	1				Colorectal(79;0.058)		CCAGTGCGCACACGGGGAGGC	0.652000													3	33					0	0	0.115264	0	0
CCDC132	55610	broad.mit.edu	37	7	92883177	92883177	+	Missense_Mutation	SNP	T	T	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr7:92883177T>G	ENST00000544910.1	+	5	360	c.140T>G	c.(139-141)cTt>cGt	p.L47R	CCDC132_ENST00000535481.1_Intron|CCDC132_ENST00000251739.5_Missense_Mutation_p.L77R|CCDC132_ENST00000541136.1_5'UTR|CCDC132_ENST00000317751.6_5'UTR|CCDC132_ENST00000305866.5_Missense_Mutation_p.L77R	NM_001257998.1	NP_001244927.1	Q96JG6	CC132_HUMAN	coiled-coil domain containing 132	77										endometrium(1)|large_intestine(2)|lung(5)	8	all_cancers(62;2.64e-11)|all_epithelial(64;1.4e-10)|Breast(17;0.000675)|Lung NSC(181;0.0618)|all_lung(186;0.0837)		STAD - Stomach adenocarcinoma(171;0.000302)			CTGTAGAAGCTTCCACCTGTT	0.338000													10	12					0	0	0.435327	0	0
CP	1356	broad.mit.edu	37	3	148924112	148924112	+	Missense_Mutation	SNP	A	A	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr3:148924112A>G	ENST00000264613.6	-	6	1313	c.1051T>C	c.(1051-1053)Ttt>Ctt	p.F351L		NM_000096.3	NP_000087.1	P00450	CERU_HUMAN	ceruloplasmin (ferroxidase)	351	F5/8 type A 1.|Plastocyanin-like 2.				cellular iron ion homeostasis|copper ion transport|transmembrane transport	extracellular space	chaperone binding|ferroxidase activity			breast(6)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(9)|lung(14)|ovary(1)|prostate(1)|soft_tissue(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	44		Prostate(884;0.00217)|Hepatocellular(537;0.00826)|Myeloproliferative disorder(1037;0.0122)|all_neural(597;0.0189)|Melanoma(1037;0.152)	LUSC - Lung squamous cell carcinoma(72;0.0473)|Lung(72;0.0607)		Drotrecogin alfa(DB00055)	ACCTGGAAAAAGGCTTGCAAA	0.433000													3	140					0	0	0.184627	0	0
SNCG	6623	broad.mit.edu	37	10	88718535	88718535	+	Silent	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr10:88718535G>A	ENST00000372017.3	+	1	123	c.81G>A	c.(79-81)acG>acA	p.T27T	SNCG_ENST00000348795.4_Silent_p.T27T	NM_003087.2	NP_003078.2	O76070	SYUG_HUMAN	synuclein, gamma (breast cancer-specific protein 1)	27	4 X 11 AA tandem repeats of [EGSA]-K-T-K- [EQ]-[GQ]-V-X(4).					microtubule organizing center|perinuclear region of cytoplasm|spindle	protein binding			endometrium(1)|skin(1)	2						AGGGGGTGACGGAAGCAGCTG	0.597000													3	69					0	0	0.217242	0	0
FRG1B	0	broad.mit.edu	37	20	29625947	29625947	+	Missense_Mutation	SNP	T	T	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr20:29625947T>C	ENST00000278882.3	+	5	571	c.191T>C	c.(190-192)aTt>aCt	p.I64T	FRG1B_ENST00000439954.2_Missense_Mutation_p.I69T|FRG1B_ENST00000358464.4_Missense_Mutation_p.I64T														p.I64T(4)		endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						TCAGATGCAATTGGACCAAGA	0.343000													3	86					0	0	0.184627	0	0
STK19	8859	broad.mit.edu	37	6	31946702	31946702	+	Missense_Mutation	SNP	A	A	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr6:31946702A>G	ENST00000375331.2	+	4	756	c.590A>G	c.(589-591)gAg>gGg	p.E197G	STK19_ENST00000375333.2_Missense_Mutation_p.E197G|STK19_ENST00000463823.1_3'UTR	NM_004197.1	NP_004188.1	P49842	STK19_HUMAN	serine/threonine kinase 19	197				QGE -> GQR (in Ref. 6; AAA99716).		nucleus	ATP binding|protein binding|protein serine/threonine kinase activity			skin(5)|upper_aerodigestive_tract(2)	7						GAGCAGGGGGAGATCAGAATC	0.532000													3	66					0	0	0.115264	0	0
TPST2	8459	broad.mit.edu	37	22	26937482	26937482	+	Missense_Mutation	SNP	G	G	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr22:26937482G>C	ENST00000338754.4	-	3	385	c.115C>G	c.(115-117)Cgg>Ggg	p.R39G	TPST2_ENST00000403880.1_Missense_Mutation_p.R39G|TPST2_ENST00000398110.2_Missense_Mutation_p.R39G	NM_003595.3	NP_003586.3	O60704	TPST2_HUMAN	tyrosylprotein sulfotransferase 2	39					peptidyl-tyrosine sulfation	endoplasmic reticulum|Golgi membrane|integral to membrane|membrane fraction	protein-tyrosine sulfotransferase activity			central_nervous_system(1)|large_intestine(1)|lung(5)	7						CGGGGGCTCCGCAGGCCCGCC	0.701000													3	41					0	0	0.115264	0	0
ELP5	23587	broad.mit.edu	37	17	7155834	7155834	+	Missense_Mutation	SNP	G	G	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr17:7155834G>C	ENST00000574993.1	+	1	230	c.13G>C	c.(13-15)Gag>Cag	p.E5Q	ELP5_ENST00000573657.1_Missense_Mutation_p.E5Q|ELP5_ENST00000396628.2_Missense_Mutation_p.E5Q|ELP5_ENST00000396627.2_Missense_Mutation_p.E5Q|ELP5_ENST00000574255.1_Missense_Mutation_p.E5Q|ELP5_ENST00000356683.2_Missense_Mutation_p.E5Q|RP1-4G17.5_ENST00000577138.1_Intron|ELP5_ENST00000354429.2_Missense_Mutation_p.E5Q					elongator acetyltransferase complex subunit 5																		GACGCCATCAGAGGGCGCCAG	0.627000													3	31					0	0	0.150653	0	0
CCDC15	80071	broad.mit.edu	37	11	124857495	124857495	+	Missense_Mutation	SNP	A	A	C	rs113451248		TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr11:124857495A>C	ENST00000529051.1	+	8	1632	c.1373A>C	c.(1372-1374)cAc>cCc	p.H458P	CCDC15_ENST00000344762.5_Missense_Mutation_p.H458P			Q0P6D6	CCD15_HUMAN	coiled-coil domain containing 15	458						centrosome				central_nervous_system(1)|cervix(1)|large_intestine(6)|lung(10)|ovary(1)|prostate(3)|skin(1)	23	all_hematologic(175;0.215)	Breast(109;0.00222)|Lung NSC(97;0.0177)|all_lung(97;0.0179)|Medulloblastoma(222;0.0425)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;1.68e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0413)		CATGTTCTCCACAAAGACCAA	0.418000													3	106					0	0	0.115264	0	0
LHX1	3975	broad.mit.edu	37	17	35297661	35297661	+	Missense_Mutation	SNP	A	A	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr17:35297661A>T	ENST00000254457.5	+	2	1656	c.245A>T	c.(244-246)aAa>aTa	p.K82I	RP11-445F12.2_ENST00000607336.1_RNA	NM_005568.3	NP_005559.2	P48742	LHX1_HUMAN	LIM homeobox 1	82	LIM zinc-binding 2.				cerebellar Purkinje cell differentiation|cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation|cervix development|comma-shaped body morphogenesis|dorsal/ventral pattern formation|ectoderm formation|embryonic pattern specification|embryonic retina morphogenesis in camera-type eye|embryonic viscerocranium morphogenesis|endoderm formation|forebrain regionalization|head development|motor axon guidance|negative regulation of transcription, DNA-dependent|nephric duct morphogenesis|nephron tubule epithelial cell differentiation|neuron migration|oviduct epithelium development|paramesonephric duct development|positive regulation of anterior head development|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of embryonic development|positive regulation of gastrulation|positive regulation of transcription, DNA-dependent|post-embryonic development|primitive streak formation|renal vesicle morphogenesis|retina layer formation|S-shaped body morphogenesis|spinal cord association neuron differentiation|transcription from RNA polymerase II promoter|ureteric bud development|uterine epithelium development|vagina development	nucleus|protein complex	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|zinc ion binding			NS(1)|central_nervous_system(1)|endometrium(3)|kidney(2)|large_intestine(1)|lung(5)|ovary(1)|prostate(1)|skin(1)	16		Breast(25;0.00607)				GCGCGGAGCAAAGTGTTTCAC	0.587000													3	21					0	0	0.115264	0	0
ATP1A2	477	broad.mit.edu	37	1	160098456	160098456	+	Silent	SNP	G	G	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr1:160098456G>C	ENST00000361216.3	+	9	1121	c.1032G>C	c.(1030-1032)ctG>ctC	p.L344L	ATP1A2_ENST00000472488.1_3'UTR|ATP1A2_ENST00000392233.3_Silent_p.L344L	NM_000702.3	NP_000693.1	P50993	AT1A2_HUMAN	ATPase, Na+/K+ transporting, alpha 2 polypeptide	344					ATP biosynthetic process		ATP binding|metal ion binding|sodium:potassium-exchanging ATPase activity			NS(1)|autonomic_ganglia(1)|breast(4)|central_nervous_system(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(13)|lung(30)|ovary(2)|skin(3)|upper_aerodigestive_tract(1)	69	all_cancers(52;1.11e-16)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.111)|LUSC - Lung squamous cell carcinoma(543;0.246)			GCCTGACCCTGACAGCCAAGC	0.572000													4	86					0	0	0.248553	0	0
TSHZ3	57616	broad.mit.edu	37	19	31770237	31770237	+	Silent	SNP	A	A	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr19:31770237A>G	ENST00000240587.4	-	2	789	c.462T>C	c.(460-462)agT>agC	p.S154S		NM_020856.2	NP_065907.2	Q63HK5	TSH3_HUMAN	teashirt zinc finger homeobox 3	154	Ser-rich.				negative regulation of transcription, DNA-dependent|regulation of respiratory gaseous exchange by neurological system process	growth cone|nucleus	chromatin binding|protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(4)|endometrium(15)|kidney(9)|large_intestine(20)|lung(60)|ovary(4)|pancreas(2)|prostate(4)|skin(5)	123	Esophageal squamous(110;0.226)					tgctgctgctactgctgctgc	0.607000													3	18					0	0	0.115264	0	0
FAT2	2196	broad.mit.edu	37	5	150922048	150922048	+	Silent	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr5:150922048G>A	ENST00000261800.5	-	9	8652	c.8640C>T	c.(8638-8640)caC>caT	p.H2880H		NM_001447.2	NP_001438.1	Q9NYQ8	FAT2_HUMAN	FAT atypical cadherin 2	2880	Cadherin 25.				epithelial cell migration|homophilic cell adhesion	cell-cell adherens junction|integral to membrane|nucleus	calcium ion binding			NS(6)|breast(3)|central_nervous_system(3)|cervix(5)|endometrium(15)|haematopoietic_and_lymphoid_tissue(4)|kidney(8)|large_intestine(61)|liver(1)|lung(60)|ovary(6)|prostate(5)|skin(5)|stomach(2)|upper_aerodigestive_tract(11)|urinary_tract(1)	196		Medulloblastoma(196;0.0912)|all_hematologic(541;0.104)	KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			TGGTCTGTCCGTGGTCATAGG	0.493000													4	144					0	0	0.184627	0	0
ANKRD30A	91074	broad.mit.edu	37	10	37431050	37431050	+	Missense_Mutation	SNP	G	G	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr10:37431050G>C	ENST00000374660.1	+	7	1156	c.1057G>C	c.(1057-1059)Gca>Cca	p.A353P	ANKRD30A_ENST00000361713.1_Missense_Mutation_p.A353P|ANKRD30A_ENST00000602533.1_Missense_Mutation_p.A353P			Q9BXX3	AN30A_HUMAN	ankyrin repeat domain 30A	409						nucleus	DNA binding|sequence-specific DNA binding transcription factor activity	p.A353P(1)		NS(1)|breast(8)|endometrium(14)|kidney(21)|large_intestine(13)|lung(70)|ovary(8)|pancreas(1)|prostate(3)|skin(15)|stomach(1)|urinary_tract(3)	158						ATTTACGTGGGCAGCAAAAGG	0.408000													3	74					0	0	0.150653	0	0
ANK2	287	broad.mit.edu	37	4	114277273	114277273	+	Missense_Mutation	SNP	C	C	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr4:114277273C>T	ENST00000357077.4	+	38	7552	c.7499C>T	c.(7498-7500)aCg>aTg	p.T2500M	ANK2_ENST00000510275.2_Intron|ANK2_ENST00000264366.6_Missense_Mutation_p.T2467M|ANK2_ENST00000509550.1_Intron|ANK2_ENST00000506722.1_Intron|ANK2_ENST00000394537.3_Intron	NM_001148.4	NP_001139.3	Q01484	ANK2_HUMAN	ankyrin 2, neuronal	2467					axon guidance|signal transduction	apical plasma membrane|basolateral plasma membrane|cytoskeleton|cytosol|sarcomere	protein binding			NS(1)|biliary_tract(1)|breast(9)|central_nervous_system(10)|cervix(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(7)|large_intestine(54)|liver(2)|lung(112)|ovary(8)|pancreas(1)|prostate(7)|skin(11)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(10)	248		Ovarian(17;0.0448)|Hepatocellular(203;0.218)		OV - Ovarian serous cystadenocarcinoma(123;4.92e-05)		GAACTCTTGACGGAAGTGGCC	0.532000													13	91					0	0	0.435327	0	0
CSPG4	1464	broad.mit.edu	37	15	75982728	75982728	+	Silent	SNP	T	T	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr15:75982728T>C	ENST00000308508.5	-	3	770	c.678A>G	c.(676-678)ctA>ctG	p.L226L		NM_001897.4	NP_001888.2	Q6UVK1	CSPG4_HUMAN	chondroitin sulfate proteoglycan 4	226	Globular or compact configuration stabilized by disulfide bonds.|Laminin G-like 2.|Neurite growth inhibition (By similarity).				angiogenesis|cell differentiation|intracellular signal transduction|positive regulation of peptidyl-tyrosine phosphorylation|tissue remodeling	apical plasma membrane|cell surface|integral to plasma membrane|intracellular|lamellipodium membrane	protein kinase binding|signal transducer activity			breast(1)|cervix(2)|endometrium(5)|kidney(5)|large_intestine(3)|liver(2)|lung(18)|ovary(2)|pancreas(2)|prostate(4)|skin(4)	48						GTGTAAACTCTAGGGTTCCTT	0.607000													3	24					0	0	0.184627	0	0
CELSR1	9620	broad.mit.edu	37	22	46785281	46785281	+	Missense_Mutation	SNP	C	C	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr22:46785281C>A	ENST00000262738.3	-	18	6460	c.6461G>T	c.(6460-6462)cGc>cTc	p.R2154L		NM_014246.1	NP_055061.1	Q9NYQ6	CELR1_HUMAN	cadherin, EGF LAG seven-pass G-type receptor 1	2154					central nervous system development|homophilic cell adhesion|neural tube closure|neuropeptide signaling pathway	integral to plasma membrane	calcium ion binding|G-protein coupled receptor activity|protein dimerization activity			breast(8)|central_nervous_system(5)|cervix(1)|endometrium(15)|haematopoietic_and_lymphoid_tissue(5)|kidney(4)|large_intestine(13)|lung(27)|ovary(2)|pancreas(2)|prostate(3)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(3)	95		Ovarian(80;0.00142)|Breast(42;0.00296)|all_neural(38;0.0416)|Colorectal(5;0.0766)		UCEC - Uterine corpus endometrioid carcinoma (28;0.00643)|BRCA - Breast invasive adenocarcinoma(115;0.171)		GTAGGCCGTGCGCACGTCATT	0.672000													3	38					0.115264	0.119875	0.115264	1	0
CASKIN1	57524	broad.mit.edu	37	16	2233835	2233835	+	Silent	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr16:2233835G>A	ENST00000343516.6	-	15	1616	c.1524C>T	c.(1522-1524)ccC>ccT	p.P508P	CASKIN1_ENST00000564289.1_Intron	NM_020764.3	NP_065815.1	Q8WXD9	CSKI1_HUMAN	CASK interacting protein 1	508	SAM 1.				signal transduction	cytoplasm				breast(1)|central_nervous_system(1)|cervix(1)|endometrium(3)|kidney(2)|liver(1)|lung(7)|ovary(4)|prostate(5)|skin(3)	28						AGCTCACCTCGGGAGTCATGC	0.667000													3	86					0	0	0.150653	0	0
ANKAR	150709	broad.mit.edu	37	2	190584454	190584454	+	Missense_Mutation	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr2:190584454G>A	ENST00000520309.1	+	11	2469	c.2381G>A	c.(2380-2382)tGt>tAt	p.C794Y	ANKAR_ENST00000313581.4_Missense_Mutation_p.C794Y|ANKAR_ENST00000431575.2_Missense_Mutation_p.C723Y|ANKAR_ENST00000281412.6_Missense_Mutation_p.C558Y|ANKAR_ENST00000438402.2_Missense_Mutation_p.C794Y	NM_144708.3	NP_653309.3	Q7Z5J8	ANKAR_HUMAN	ankyrin and armadillo repeat containing	794						integral to membrane	binding			breast(3)|central_nervous_system(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(7)|liver(2)|lung(16)|ovary(2)|pancreas(1)|skin(1)|urinary_tract(2)	46			OV - Ovarian serous cystadenocarcinoma(117;0.00156)|Epithelial(96;0.0256)|all cancers(119;0.0744)			CTACTGGTTTGTGATGAGCCT	0.398000													23	41					0	0	0.654019	0	0
ARHGEF10L	55160	broad.mit.edu	37	1	17953976	17953976	+	Missense_Mutation	SNP	G	G	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr1:17953976G>T	ENST00000361221.3	+	15	1721	c.1562G>T	c.(1561-1563)aGt>aTt	p.S521I	ARHGEF10L_ENST00000167825.4_Missense_Mutation_p.S229I|ARHGEF10L_ENST00000375420.3_Missense_Mutation_p.S279I|ARHGEF10L_ENST00000375408.3_Missense_Mutation_p.S299I|ARHGEF10L_ENST00000375415.1_Missense_Mutation_p.S482I|ARHGEF10L_ENST00000452522.1_Missense_Mutation_p.S482I|ARHGEF10L_ENST00000469726.1_3'UTR|ARHGEF10L_ENST00000434513.1_Missense_Mutation_p.S521I	NM_018125.3	NP_060595.3	Q9HCE6	ARGAL_HUMAN	Rho guanine nucleotide exchange factor (GEF) 10-like	521					regulation of Rho protein signal transduction	cytoplasm	Rho guanyl-nucleotide exchange factor activity			NS(1)|breast(1)|central_nervous_system(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(5)|liver(2)|lung(16)|ovary(4)|pancreas(1)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)	43		Colorectal(325;3.46e-05)|Breast(348;0.000162)|all_lung(284;0.000337)|Lung NSC(340;0.000419)|Renal(390;0.000518)|Ovarian(437;0.00409)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00598)|COAD - Colon adenocarcinoma(227;1.62e-05)|BRCA - Breast invasive adenocarcinoma(304;1.68e-05)|Kidney(64;0.000269)|KIRC - Kidney renal clear cell carcinoma(64;0.00361)|STAD - Stomach adenocarcinoma(196;0.00656)|READ - Rectum adenocarcinoma(331;0.0718)|Lung(427;0.204)		AAGAGCGTCAGTGACCGCAGC	0.667000													3	29					0.00024832	0.000274737	0.150653	1	0
LENG8	114823	broad.mit.edu	37	19	54969308	54969308	+	Missense_Mutation	SNP	C	C	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr19:54969308C>G	ENST00000326764.5	+	14	2408	c.1929C>G	c.(1927-1929)tgC>tgG	p.C643W	LENG8_ENST00000376514.2_Intron	NM_052925.2	NP_443157.1	Q96PV6	LENG8_HUMAN	leukocyte receptor cluster (LRC) member 8	606							protein binding			breast(1)|central_nervous_system(3)|endometrium(3)|kidney(1)|large_intestine(6)|lung(9)|pancreas(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	30	Ovarian(34;0.19)			GBM - Glioblastoma multiforme(193;0.139)		TTAACCAGTGCCAGACGCAGC	0.572000													13	123					0	0	0.557998	0	0
SGK3	23678	broad.mit.edu	37	8	67705990	67705990	+	Missense_Mutation	SNP	A	A	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr8:67705990A>G	ENST00000396596.1	+	2	233	c.19A>G	c.(19-21)Atg>Gtg	p.M7V	SGK3_ENST00000345714.4_Missense_Mutation_p.M7V|SGK3_ENST00000521198.2_Missense_Mutation_p.M7V|C8orf44-SGK3_ENST00000520044.1_3'UTR|C8orf44-SGK3_ENST00000519289.1_Missense_Mutation_p.M7V|SGK3_ENST00000522398.1_Missense_Mutation_p.M7V|SGK3_ENST00000520976.1_Missense_Mutation_p.M7V	NM_013257.4	NP_037389.4	Q96BR1	SGK3_HUMAN	serum/glucocorticoid regulated kinase family, member 3	7					cell communication|response to stress	cytoplasmic membrane-bounded vesicle|early endosome	ATP binding|phosphatidylinositol binding|protein serine/threonine kinase activity			breast(1)|endometrium(2)|kidney(2)|large_intestine(2)|lung(9)|ovary(1)|upper_aerodigestive_tract(1)	18	Breast(64;0.186)	Lung NSC(129;0.0908)|all_lung(136;0.152)	Epithelial(68;0.0046)|OV - Ovarian serous cystadenocarcinoma(28;0.0112)|all cancers(69;0.0141)|BRCA - Breast invasive adenocarcinoma(89;0.206)			AGATCACACCATGGACTACAA	0.403000													16	27					0	0	0.608945	0	0
SCNN1G	6340	broad.mit.edu	37	16	23200962	23200962	+	Missense_Mutation	SNP	C	C	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr16:23200962C>G	ENST00000300061.2	+	3	731	c.588C>G	c.(586-588)atC>atG	p.I196M		NM_001039.3	NP_001030.2	P51170	SCNNG_HUMAN	sodium channel, non-voltage-gated 1, gamma subunit	196					excretion|sensory perception of taste	apical plasma membrane|integral to plasma membrane	ligand-gated sodium channel activity|WW domain binding			NS(2)|autonomic_ganglia(1)|breast(1)|cervix(2)|kidney(1)|large_intestine(9)|lung(9)|ovary(2)|pancreas(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)	34				GBM - Glioblastoma multiforme(48;0.0366)	Amiloride(DB00594)|Triamterene(DB00384)	TCATGCACATCGAGTCCAAGC	0.517000													5	284					0	0	0.217242	0	0
ANGPTL5	253935	broad.mit.edu	37	11	101775573	101775573	+	Silent	SNP	A	A	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr11:101775573A>G	ENST00000334289.3	-	5	1006	c.411T>C	c.(409-411)ccT>ccC	p.P137P		NM_178127.4	NP_835228.2	Q86XS5	ANGL5_HUMAN	angiopoietin-like 5	137					signal transduction	extracellular space	receptor binding			breast(1)|endometrium(1)|kidney(2)|large_intestine(10)|lung(10)|ovary(2)|skin(3)	29		Acute lymphoblastic leukemia(157;0.000966)|all_hematologic(158;0.043)		BRCA - Breast invasive adenocarcinoma(274;0.0328)		TGTGAGGAAAAGGATCCAGCT	0.358000													3	72					0	0	0.184627	0	0
AC015818.3	0	broad.mit.edu	37	17	20424245	20424245	+	RNA	SNP	C	C	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr17:20424245C>T	ENST00000582261.1	-	0	1810																											GCTCCAGCTGCGTCTTCACGT	0.632000													3	5					0	0	0.184627	0	0
SEMA3A	10371	broad.mit.edu	37	7	83640389	83640389	+	Missense_Mutation	SNP	T	T	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr7:83640389T>G	ENST00000265362.3	-	9	1258	c.944A>C	c.(943-945)aAc>aCc	p.N315T	SEMA3A_ENST00000436949.1_Missense_Mutation_p.N315T	NM_006080.2	NP_006071.1	Q14563	SEM3A_HUMAN	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	315	Sema.				axon guidance	extracellular region|membrane	receptor activity			breast(3)|cervix(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(12)|liver(1)|lung(22)|ovary(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	53						ATCTTTAAAGTTCATTAGGAA	0.299000													6	44					0	0	0.217242	0	0
TSHZ3	57616	broad.mit.edu	37	19	31770234	31770234	+	Silent	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr19:31770234G>A	ENST00000240587.4	-	2	792	c.465C>T	c.(463-465)agC>agT	p.S155S		NM_020856.2	NP_065907.2	Q63HK5	TSH3_HUMAN	teashirt zinc finger homeobox 3	155	Ser-rich.				negative regulation of transcription, DNA-dependent|regulation of respiratory gaseous exchange by neurological system process	growth cone|nucleus	chromatin binding|protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding	p.S155S(1)		breast(4)|endometrium(15)|kidney(9)|large_intestine(20)|lung(60)|ovary(4)|pancreas(2)|prostate(4)|skin(5)	123	Esophageal squamous(110;0.226)					tgctgctgctgctactgctgc	0.612000													3	17					0	0	0.115264	0	0
LRFN5	145581	broad.mit.edu	37	14	42356070	42356070	+	Missense_Mutation	SNP	C	C	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr14:42356070C>A	ENST00000554171.1	+	5	2674	c.242C>A	c.(241-243)aCt>aAt	p.T81N	LRFN5_ENST00000298119.4_Missense_Mutation_p.T81N|LRFN5_ENST00000554120.1_Missense_Mutation_p.T81N			Q96NI6	LRFN5_HUMAN	leucine rich repeat and fibronectin type III domain containing 5	81						integral to membrane				breast(1)|central_nervous_system(1)|cervix(1)|endometrium(3)|kidney(4)|large_intestine(12)|liver(1)|lung(67)|ovary(5)|pancreas(3)|prostate(1)|skin(9)|stomach(1)|upper_aerodigestive_tract(9)|urinary_tract(2)	120			LUAD - Lung adenocarcinoma(50;0.0223)|Lung(238;0.0728)	GBM - Glioblastoma multiforme(112;0.00847)		GTGGACCTGACTCTATCCAGG	0.373000										HNSCC(30;0.082)			27	36					5.45727e-16	6.30618e-16	0.729181	1	0
XIST	0	broad.mit.edu	37	X	73066504	73066504	+	RNA	SNP	A	A	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chrX:73066504A>T	ENST00000429829.1	-	0	6084					NR_001564.2																						GGAAGGGAAAAGTGGGGATGA	0.478000													4	19					0	0	0.217242	0	0
ANKAR	150709	broad.mit.edu	37	2	190557050	190557050	+	Missense_Mutation	SNP	T	T	C			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr2:190557050T>C	ENST00000520309.1	+	4	1197	c.1109T>C	c.(1108-1110)tTt>tCt	p.F370S	ANKAR_ENST00000461516.1_Intron|ANKAR_ENST00000281412.6_Missense_Mutation_p.F134S|ANKAR_ENST00000313581.4_Missense_Mutation_p.F370S|ANKAR_ENST00000431575.2_Missense_Mutation_p.F299S|ANKAR_ENST00000438402.2_Missense_Mutation_p.F370S	NM_144708.3	NP_653309.3	Q7Z5J8	ANKAR_HUMAN	ankyrin and armadillo repeat containing	370						integral to membrane	binding			breast(3)|central_nervous_system(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(7)|liver(2)|lung(16)|ovary(2)|pancreas(1)|skin(1)|urinary_tract(2)	46			OV - Ovarian serous cystadenocarcinoma(117;0.00156)|Epithelial(96;0.0256)|all cancers(119;0.0744)			TGCCAGAATTTTCACTACAAA	0.318000													9	40					0	0	0.361761	0	0
GALNT10	55568	broad.mit.edu	37	5	153760070	153760070	+	Missense_Mutation	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr5:153760070G>A	ENST00000297107.6	+	6	954	c.817G>A	c.(817-819)Gac>Aac	p.D273N	SAP30L-AS1_ENST00000519727.1_RNA|GALNT10_ENST00000519544.1_3'UTR|GALNT10_ENST00000377661.2_Missense_Mutation_p.D211N|GALNT10_ENST00000425427.2_Missense_Mutation_p.D273N	NM_198321.3	NP_938080.1	Q86SR1	GLT10_HUMAN	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)	273						Golgi membrane|integral to membrane	metal ion binding|polypeptide N-acetylgalactosaminyltransferase activity|sugar binding			cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(7)|lung(12)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)	32	Renal(175;0.00488)	Medulloblastoma(196;0.0354)|all_neural(177;0.147)|all_hematologic(541;0.21)	Kidney(363;8.21e-05)|KIRC - Kidney renal clear cell carcinoma(527;0.000577)			TGACCATGACGACTTTCGGTA	0.532000													17	185					0	0	0.575678	0	0
RNF43	54894	broad.mit.edu	37	17	56434877	56434877	+	Missense_Mutation	SNP	C	C	G			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr17:56434877C>G	ENST00000584437.1	-	8	4215	c.2260G>C	c.(2260-2262)Ggc>Cgc	p.G754R	RNF43_ENST00000407977.2_Missense_Mutation_p.G754R|RNF43_ENST00000583753.1_Missense_Mutation_p.G713R|RNF43_ENST00000500597.2_Missense_Mutation_p.G713R|RNF43_ENST00000577625.1_Missense_Mutation_p.G627R|BZRAP1-AS1_ENST00000583841.1_RNA|RNF43_ENST00000577716.1_Missense_Mutation_p.G754R|RNF43_ENST00000581868.1_Missense_Mutation_p.G627R			Q68DV7	RNF43_HUMAN	ring finger protein 43	754	Pro-rich.					endoplasmic reticulum membrane|integral to membrane|nuclear envelope	ligase activity|protein binding|zinc ion binding			NS(1)|biliary_tract(5)|breast(1)|central_nervous_system(1)|endometrium(10)|kidney(2)|large_intestine(14)|lung(9)|ovary(2)|pancreas(10)|prostate(1)|skin(4)	60	Medulloblastoma(34;0.127)|all_neural(34;0.237)					CATGGCCTGCCCTCTGCGGTG	0.597000													16	99					0	0	0.539581	0	0
ARMS2	387715	broad.mit.edu	37	10	124214267	124214267	+	Silent	SNP	G	G	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr10:124214267G>T	ENST00000528446.1	+	1	99	c.24G>T	c.(22-24)ccG>ccT	p.P8P		NM_001099667.1	NP_001093137.1	P0C7Q2	ARMS2_HUMAN	age-related maculopathy susceptibility 2	8					retina homeostasis	mitochondrion|photoreceptor inner segment				ovary(1)	1		all_neural(114;0.0765)|Lung NSC(174;0.132)|all_lung(145;0.163)|Breast(234;0.238)				ACCCAGGACCGATGGTAACTG	0.572000													3	109					0.115264	0.119875	0.115264	1	0
TUBGCP6	85378	broad.mit.edu	37	22	50659212	50659212	+	Silent	SNP	A	A	G	rs141527317		TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr22:50659212A>G	ENST00000439308.2	-	16	4068	c.3576T>C	c.(3574-3576)tcT>tcC	p.S1192S	TUBGCP6_ENST00000491449.1_5'UTR|TUBGCP6_ENST00000248846.5_Silent_p.S1192S	NM_020461.3	NP_065194.2	Q96RT7	GCP6_HUMAN	tubulin, gamma complex associated protein 6	1192	9 X 27 AA tandem repeats.				G2/M transition of mitotic cell cycle|microtubule nucleation	centrosome|cytosol|gamma-tubulin ring complex|microtubule|spindle pole	microtubule binding			breast(4)|central_nervous_system(2)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(4)|lung(13)|ovary(3)|prostate(2)|skin(2)	45		all_cancers(38;5.79e-13)|all_epithelial(38;1.71e-11)|all_lung(38;3.89e-05)|Breast(42;0.000523)|Lung NSC(38;0.000992)|Ovarian(80;0.0221)|Hepatocellular(38;0.0691)|Lung SC(80;0.113)		LUAD - Lung adenocarcinoma(64;0.109)|BRCA - Breast invasive adenocarcinoma(115;0.21)		TGCTGGCATCAGACACGTGTC	0.617000													4	90					0	0	0.184627	0	0
HLA-DQB2	3120	broad.mit.edu	37	6	32725559	32725559	+	Missense_Mutation	SNP	C	C	T	rs113761247	byFrequency	TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr6:32725559C>T	ENST00000435145.2	-	4	809	c.748G>A	c.(748-750)Ggt>Agt	p.G250S	HLA-DQB2_ENST00000411527.1_Intron|HLA-DQB2_ENST00000437316.2_Missense_Mutation_p.G250S			Q5SR06	Q5SR06_HUMAN	major histocompatibility complex, class II, DQ beta 2	216					antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|immune response	integral to membrane|MHC class II protein complex				endometrium(1)|kidney(1)|lung(1)|prostate(2)	5						CCTTTCTGACCCCTGTGACGG	0.552000													6	26					0	0	0.307466	0	0
PTPRA	0	broad.mit.edu	37	20	2988040	2988040	+	Missense_Mutation	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr20:2988040G>A	ENST00000216877.6	+	10	1253	c.853G>A	c.(853-855)Gat>Aat	p.D285N	PTPRA_ENST00000358719.4_Missense_Mutation_p.D150N|PTPRA_ENST00000425918.2_Missense_Mutation_p.D305N|PTPRA_ENST00000318266.5_Missense_Mutation_p.D285N|PTPRA_ENST00000399903.2_Missense_Mutation_p.D294N|PTPRA_ENST00000380393.3_Missense_Mutation_p.D294N|PTPRA_ENST00000356147.3_Missense_Mutation_p.D285N	NM_080840.2	NP_543030.1	P18433	PTPRA_HUMAN	protein tyrosine phosphatase, receptor type, A	294	Tyrosine-protein phosphatase 1.				axon guidance|protein phosphorylation	integral to plasma membrane	transmembrane receptor protein tyrosine phosphatase activity			NS(1)|breast(1)|endometrium(3)|large_intestine(3)|lung(5)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	17						TCCAGATTCTGATTACATCAA	0.448000													48	95					0	0	0.870114	0	0
SERPINA6	866	broad.mit.edu	37	14	94780979	94780979	+	Missense_Mutation	SNP	G	G	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr14:94780979G>A	ENST00000341584.3	-	2	153	c.7C>T	c.(7-9)Ctc>Ttc	p.L3F		NM_001756.3	NP_001747.2	P08185	CBG_HUMAN	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	3					regulation of proteolysis|transport	extracellular space	serine-type endopeptidase inhibitor activity|steroid binding			central_nervous_system(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(11)|ovary(1)|skin(4)|upper_aerodigestive_tract(1)	26		all_cancers(154;0.0482)|all_epithelial(191;0.166)		COAD - Colon adenocarcinoma(157;0.211)	Alclometasone(DB00240)|Beclomethasone(DB00394)|Ciclesonide(DB01410)|Flumethasone Pivalate(DB00663)|Flunisolide(DB00180)|Fluocinolone Acetonide(DB00591)|Fluocinonide(DB01047)|Fluorometholone(DB00324)|Flurandrenolide(DB00846)|Fluticasone Propionate(DB00588)|Halobetasol Propionate(DB00596)|Medrysone(DB00253)|Mitotane(DB00648)|Paramethasone(DB01384)|Prednisolone(DB00860)|Rimexolone(DB00896)|Triamcinolone(DB00620)	TACAGGAGGAGTGGCATTGTC	0.547000													14	101					0	0	0.539581	0	0
MAST2	23139	broad.mit.edu	37	1	46495849	46495849	+	Frame_Shift_Del	DEL	T	T	-			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr1:46495849delT	ENST00000361297.2	+	21	2775	c.2492delT	c.(2491-2493)ggfs	p.V831fs	MAST2_ENST00000372009.2_Frame_Shift_Del_p.V761fs|MAST2_ENST00000372008.1_Frame_Shift_Del_p.V716fs|MAST2_ENST00000477968.1_3'UTR	NM_015112.2	NP_055927.2	Q6P0Q8	MAST2_HUMAN	microtubule associated serine/threonine kinase 2	831	AGC-kinase C-terminal.				regulation of interleukin-12 biosynthetic process|spermatid differentiation	cytoplasm|cytoskeleton|plasma membrane	ATP binding|magnesium ion binding|phosphatase binding|protein serine/threonine kinase activity			breast(1)|lung(3)|ovary(5)|stomach(2)	11	Acute lymphoblastic leukemia(166;0.155)|Lung SC(450;0.184)					GAGGAAGAAGTGAGTGAGGAT	0.572													12	90	---	---	---	---					
APOB	338	broad.mit.edu	37	2	21231438	21231440	+	In_Frame_Del	DEL	GAG	GAG	-			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr2:21231438_21231440delGAG	ENST00000233242.1	-	26	8427_8429	c.8300_8302delCTC	c.(8299-8304)ctt>c	p.PL2767del		NM_000384.2	NP_000375.2	P04114	APOB_HUMAN	apolipoprotein B	2767					cholesterol homeostasis|cholesterol metabolic process|leukocyte migration|low-density lipoprotein particle clearance|low-density lipoprotein particle remodeling|platelet activation|positive regulation of cholesterol storage|positive regulation of macrophage derived foam cell differentiation|receptor-mediated endocytosis|response to virus	chylomicron remnant|clathrin-coated endocytic vesicle membrane|endoplasmic reticulum lumen|endoplasmic reticulum membrane|endosome lumen|endosome membrane|intermediate-density lipoprotein particle|low-density lipoprotein particle|mature chylomicron|microsome|plasma membrane|very-low-density lipoprotein particle	cholesterol transporter activity|enzyme binding|heparin binding|low-density lipoprotein particle receptor binding|phospholipid binding|protein heterodimerization activity			NS(5)|autonomic_ganglia(1)|breast(6)|central_nervous_system(4)|cervix(3)|endometrium(19)|kidney(10)|large_intestine(63)|liver(5)|lung(125)|ovary(16)|pancreas(1)|prostate(5)|skin(31)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(6)	305	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)				Atorvastatin(DB01076)	AATGTGAAAAGAGGAGATTGGAT	0.438													17	184	---	---	---	---					
AC093838.4	0	broad.mit.edu	37	2	132266282	132266282	+	RNA	DEL	G	G	-	rs74537446		TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr2:132266282delG	ENST00000438378.2	+	0	1234					NR_026922.1																						GCTGGATGGTGGGAAGCAGAA	0.547													8	8	---	---	---	---					
PIKFYVE	200576	broad.mit.edu	37	2	209163430	209163439	+	Frame_Shift_Del	DEL	CATCTGTCAG	CATCTGTCAG	-	rs150646524		TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr2:209163430_209163439delCATCTGTCAG	ENST00000264380.4	+	8	1135_1144	c.977_986delCATCTGTCAG	c.(976-987)atfs	p.TSVS326fs	PIKFYVE_ENST00000392202.3_Frame_Shift_Del_p.TSVS229fs|PIKFYVE_ENST00000407449.1_Frame_Shift_Del_p.TSVS326fs|PIKFYVE_ENST00000308862.6_Frame_Shift_Del_p.TSVS240fs	NM_015040.3	NP_055855.2	Q9Y2I7	FYV1_HUMAN	phosphoinositide kinase, FYVE finger containing	326					cellular protein metabolic process|intracellular signal transduction|protein localization to nucleus|retrograde transport, endosome to Golgi	early endosome membrane|membrane raft	1-phosphatidylinositol-3-phosphate 5-kinase activity|1-phosphatidylinositol-4-phosphate 5-kinase activity|ATP binding|metal ion binding|protein binding	p.S327F(1)		NS(1)|autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|endometrium(14)|kidney(6)|large_intestine(25)|lung(40)|ovary(7)|pancreas(1)|prostate(3)|skin(3)|upper_aerodigestive_tract(2)|urinary_tract(2)	107						TCATATGAGACATCTGTCAGTCCCCAGGCT	0.429													23	62	---	---	---	---					
APC	324	broad.mit.edu	37	5	112175599	112175600	+	Frame_Shift_Ins	INS	-	-	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr5:112175599_112175600insA	ENST00000457016.1	+	16	4688_4689	c.4308_4309insA	c.(4306-4311)agaaacfs	p.N1437fs	APC_ENST00000508376.2_Frame_Shift_Ins_p.N1437fs|APC_ENST00000257430.4_Frame_Shift_Ins_p.N1437fs|CTC-554D6.1_ENST00000520401.1_Intron			P25054	APC_HUMAN	adenomatous polyposis coli	1437	Ser-rich.				canonical Wnt receptor signaling pathway|cell adhesion|cell cycle arrest|cell migration|cellular component disassembly involved in apoptosis|cytokinesis after mitosis|mitotic cell cycle spindle assembly checkpoint|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of cyclin-dependent protein kinase activity|negative regulation of microtubule depolymerization|positive regulation of apoptosis|positive regulation of cell migration|positive regulation of pseudopodium assembly|protein complex assembly|regulation of attachment of spindle microtubules to kinetochore|response to DNA damage stimulus|tight junction assembly	adherens junction|APC-Axin-1-beta-catenin complex|Axin-APC-beta-catenin-GSK3B complex|beta-catenin destruction complex|centrosome|cytosol|kinetochore|lamellipodium|lateral plasma membrane|nucleus|ruffle membrane|tight junction	beta-catenin binding|gamma-catenin binding|microtubule plus-end binding|protein kinase binding|protein kinase regulator activity	p.S1436fs*37(3)|p.?(1)|p.P1424fs*19(1)|p.K1192fs*3(1)|p.P1432fs*35(1)|p.S1436fs*36(1)|p.S1436fs*33(1)|p.S1436fs*22(1)|p.K1437*(1)		NS(7)|adrenal_gland(6)|biliary_tract(5)|bone(6)|breast(29)|central_nervous_system(12)|cervix(2)|endometrium(12)|haematopoietic_and_lymphoid_tissue(6)|kidney(8)|large_intestine(2768)|liver(15)|lung(39)|oesophagus(1)|ovary(12)|pancreas(27)|prostate(15)|salivary_gland(2)|skin(14)|small_intestine(34)|soft_tissue(55)|stomach(136)|thyroid(22)|upper_aerodigestive_tract(8)|urinary_tract(20)	3261		all_cancers(142;3.01e-27)|all_epithelial(76;2.3e-18)|all_hematologic(541;4.32e-09)|Ovarian(225;1.78e-06)|Lung NSC(167;0.000195)|Breast(839;0.000231)|all_lung(232;0.000247)|Colorectal(10;0.000355)|Prostate(80;0.00133)		OV - Ovarian serous cystadenocarcinoma(64;1.09e-113)|Epithelial(69;3.79e-112)|all cancers(49;1.67e-104)|BRCA - Breast invasive adenocarcinoma(61;0.00136)|COAD - Colon adenocarcinoma(37;0.00155)|Colorectal(14;0.00191)		CAAGCAGAAGTAAAACACCTCC	0.480		12	"""D, Mis, N, F, S"""		"""colorectal, pancreatic, desmoid, hepatoblastoma, glioma, other CNS"""	"""colorectal, pancreatic, desmoid, hepatoblastoma, glioma, other CNS"""			Turcot syndrome;Hereditary Desmoid Disease;Familial Adenomatous Polyposis	TSP Lung(16;0.13)			7	58	---	---	---	---					
ATG16L2	89849	broad.mit.edu	37	11	72528863	72528865	+	In_Frame_Del	DEL	AGG	AGG	-			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr11:72528863_72528865delAGG	ENST00000321297.5	+	3	419_421	c.281_283delAGG	c.(280-285)cag>c	p.QE94del	ATG16L2_ENST00000534905.1_In_Frame_Del_p.QE94del	NM_033388.1	NP_203746.1	Q8NAA4	A16L2_HUMAN	autophagy related 16-like 2 (S. cerevisiae)	94					autophagy|protein transport	cytoplasm	protein binding			breast(1)|cervix(1)|endometrium(2)|large_intestine(1)|lung(9)	14			BRCA - Breast invasive adenocarcinoma(5;2.73e-06)			GTGAAGTGGCAGGAGGAGGAGGA	0.591													7	89	---	---	---	---					
PRB2	653247	broad.mit.edu	37	12	11546788	11546790	+	In_Frame_Del	DEL	GGA	GGA	-			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr12:11546788_11546790delGGA	ENST00000389362.4	-	3	257_259	c.222_224delTCC	c.(220-225)cca>cc	p.PP74del	PRB1_ENST00000546254.1_Intron	NM_006248.3	NP_006239.3			proline-rich protein BstNI subfamily 2											NS(1)|breast(1)|endometrium(2)|kidney(3)|large_intestine(3)|lung(14)|pancreas(1)|prostate(5)|skin(4)|stomach(2)|urinary_tract(1)	37		all_cancers(2;0.00558)|Acute lymphoblastic leukemia(2;3.94e-11)|all_hematologic(2;3.6e-09)	OV - Ovarian serous cystadenocarcinoma(49;0.185)			TGGCTTTCCTGGAGGAGGTGGGG	0.601													7	308	---	---	---	---					
SMCR7	0	broad.mit.edu	37	17	18167778	18167780	+	In_Frame_Del	DEL	GCT	GCT	-			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr17:18167778_18167780delGCT	ENST00000323019.4	+	4	1276_1278	c.1065_1067delGCT	c.(1063-1068)cgg>cg	p.RL355del	SMCR7_ENST00000395704.4_3'UTR|SMCR7_ENST00000395706.2_In_Frame_Del_p.RL366del	NM_001144900.1|NM_139162.3	NP_001138372.1|NP_631901.2	Q96C03	SMCR7_HUMAN		355						integral to membrane	protein binding	p.L356R(1)		breast(1)|central_nervous_system(1)|endometrium(3)|lung(4)	9	all_neural(463;0.228)					CTCGCCGGCGGCTGCTGCTGCTG	0.685													7	75	---	---	---	---					
OR7E24	26648	broad.mit.edu	37	19	9361740	9361741	+	Frame_Shift_Ins	INS	-	-	T			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr19:9361740_9361741insT	ENST00000456448.1	+	1	135_136	c.21_22insT	c.(19-24)ctttttfs	p.LF7fs		NM_001079935.1	NP_001073404.1	Q6IFN5	O7E24_HUMAN	olfactory receptor, family 7, subfamily E, member 24	7					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			endometrium(1)|large_intestine(3)|lung(8)|ovary(1)|prostate(1)|skin(2)	16						TTCCAATTCTCTTTTTTTTTTT	0.386													3	6	---	---	---	---					
C22orf43	51233	broad.mit.edu	37	22	23959767	23959769	+	In_Frame_Del	DEL	CAT	CAT	-			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-10A-01D-2115-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	7f5954b3-ce60-414b-bd40-f46175ba19c4	g.chr22:23959767_23959769delCAT	ENST00000317749.5	-	7	809_811	c.512_514delATG	c.(511-516)gcc>g	p.DA171del		NM_016449.3	NP_057533.2	Q6PGQ1	CV043_HUMAN	chromosome 22 open reading frame 43	171	Asp-rich.									endometrium(1)|large_intestine(3)|lung(5)|pancreas(1)|skin(1)	11						CTTACCTGGGcatcatcatcatc	0.433													7	74	---	---	---	---					
MAST2	23139	broad.mit.edu	37	1	46495849	46495849	+	Frame_Shift_Del	DEL	T	T	-			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr1:46495849delT	ENST00000361297.2	+	21	2775	c.2492delT	c.(2491-2493)ggfs	p.V831fs	MAST2_ENST00000372008.1_Frame_Shift_Del_p.V716fs|MAST2_ENST00000372009.2_Frame_Shift_Del_p.V761fs|MAST2_ENST00000477968.1_3'UTR	NM_015112.2	NP_055927.2	Q6P0Q8	MAST2_HUMAN	microtubule associated serine/threonine kinase 2	831	AGC-kinase C-terminal.				regulation of interleukin-12 biosynthetic process|spermatid differentiation	cytoplasm|cytoskeleton|plasma membrane	ATP binding|magnesium ion binding|phosphatase binding|protein serine/threonine kinase activity			breast(1)|lung(3)|ovary(5)|stomach(2)	11	Acute lymphoblastic leukemia(166;0.155)|Lung SC(450;0.184)					GAGGAAGAAGTGAGTGAGGAT	0.572													12	90	---	---	---	---					
APOB	338	broad.mit.edu	37	2	21231438	21231440	+	In_Frame_Del	DEL	GAG	GAG	-			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr2:21231438_21231440delGAG	ENST00000233242.1	-	26	8427_8429	c.8300_8302delCTC	c.(8299-8304)ctt>c	p.PL2767del		NM_000384.2	NP_000375.2	P04114	APOB_HUMAN	apolipoprotein B	2767					cholesterol homeostasis|cholesterol metabolic process|leukocyte migration|low-density lipoprotein particle clearance|low-density lipoprotein particle remodeling|platelet activation|positive regulation of cholesterol storage|positive regulation of macrophage derived foam cell differentiation|receptor-mediated endocytosis|response to virus	chylomicron remnant|clathrin-coated endocytic vesicle membrane|endoplasmic reticulum lumen|endoplasmic reticulum membrane|endosome lumen|endosome membrane|intermediate-density lipoprotein particle|low-density lipoprotein particle|mature chylomicron|microsome|plasma membrane|very-low-density lipoprotein particle	cholesterol transporter activity|enzyme binding|heparin binding|low-density lipoprotein particle receptor binding|phospholipid binding|protein heterodimerization activity			NS(5)|autonomic_ganglia(1)|breast(6)|central_nervous_system(4)|cervix(3)|endometrium(19)|kidney(10)|large_intestine(63)|liver(5)|lung(125)|ovary(16)|pancreas(1)|prostate(5)|skin(31)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(6)	305	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)				Atorvastatin(DB01076)	AATGTGAAAAGAGGAGATTGGAT	0.438													17	184	---	---	---	---					
PIKFYVE	200576	broad.mit.edu	37	2	209163430	209163439	+	Frame_Shift_Del	DEL	CATCTGTCAG	CATCTGTCAG	-	rs150646524		TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr2:209163430_209163439delCATCTGTCAG	ENST00000264380.4	+	8	1135_1144	c.977_986delCATCTGTCAG	c.(976-987)atfs	p.TSVS326fs	PIKFYVE_ENST00000392202.3_Frame_Shift_Del_p.TSVS229fs|PIKFYVE_ENST00000407449.1_Frame_Shift_Del_p.TSVS326fs|PIKFYVE_ENST00000308862.6_Frame_Shift_Del_p.TSVS240fs	NM_015040.3	NP_055855.2	Q9Y2I7	FYV1_HUMAN	phosphoinositide kinase, FYVE finger containing	326					cellular protein metabolic process|intracellular signal transduction|protein localization to nucleus|retrograde transport, endosome to Golgi	early endosome membrane|membrane raft	1-phosphatidylinositol-3-phosphate 5-kinase activity|1-phosphatidylinositol-4-phosphate 5-kinase activity|ATP binding|metal ion binding|protein binding	p.S327F(1)		NS(1)|autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|endometrium(14)|kidney(6)|large_intestine(25)|lung(40)|ovary(7)|pancreas(1)|prostate(3)|skin(3)|upper_aerodigestive_tract(2)|urinary_tract(2)	107						TCATATGAGACATCTGTCAGTCCCCAGGCT	0.429													23	62	---	---	---	---					
XPC	7508	broad.mit.edu	37	3	14219966	14219968	+	Splice_Site	DEL	CCT	CCT	-	rs72561774		TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr3:14219966_14219968delCCT	ENST00000285021.7	-	1	315_317	c.103_splice	c.e1+1	p.ED34_splice	XPC_ENST00000449060.2_Splice_Site_p.ED34_splice|LSM3_ENST00000306024.3_5'UTR	NM_001145769.1|NM_004628.4	NP_001139241.1|NP_004619.3	Q01831	XPC_HUMAN	xeroderma pigmentosum, complementation group C	34	Glu-rich (acidic).|Poly-Glu.				nucleotide-excision repair, DNA damage recognition|nucleotide-excision repair, DNA damage removal	cytoplasm|nucleoplasm|XPC complex	bubble DNA binding|damaged DNA binding|loop DNA binding|protein binding|single-stranded DNA binding	p.E34delE(1)		NS(1)|breast(2)|endometrium(1)|kidney(3)|large_intestine(4)|lung(5)|ovary(3)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	22						TCGCTCTCACCCTCCTCCTCCTC	0.734			"""Mis, N, F, S"""			"""skin basal cell, skin squamous cell, melanoma"""		Nucleotide excision repair (NER)	Xeroderma Pigmentosum				11	53	---	---	---	---					
APC	324	broad.mit.edu	37	5	112175599	112175600	+	Frame_Shift_Ins	INS	-	-	A			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr5:112175599_112175600insA	ENST00000457016.1	+	16	4688_4689	c.4308_4309insA	c.(4306-4311)agaaacfs	p.N1437fs	CTC-554D6.1_ENST00000520401.1_Intron|APC_ENST00000508376.2_Frame_Shift_Ins_p.N1437fs|APC_ENST00000257430.4_Frame_Shift_Ins_p.N1437fs			P25054	APC_HUMAN	adenomatous polyposis coli	1437	Ser-rich.				canonical Wnt receptor signaling pathway|cell adhesion|cell cycle arrest|cell migration|cellular component disassembly involved in apoptosis|cytokinesis after mitosis|mitotic cell cycle spindle assembly checkpoint|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of cyclin-dependent protein kinase activity|negative regulation of microtubule depolymerization|positive regulation of apoptosis|positive regulation of cell migration|positive regulation of pseudopodium assembly|protein complex assembly|regulation of attachment of spindle microtubules to kinetochore|response to DNA damage stimulus|tight junction assembly	adherens junction|APC-Axin-1-beta-catenin complex|Axin-APC-beta-catenin-GSK3B complex|beta-catenin destruction complex|centrosome|cytosol|kinetochore|lamellipodium|lateral plasma membrane|nucleus|ruffle membrane|tight junction	beta-catenin binding|gamma-catenin binding|microtubule plus-end binding|protein kinase binding|protein kinase regulator activity	p.S1436fs*37(3)|p.?(1)|p.P1424fs*19(1)|p.K1192fs*3(1)|p.P1432fs*35(1)|p.S1436fs*36(1)|p.S1436fs*33(1)|p.S1436fs*22(1)|p.K1437*(1)		NS(7)|adrenal_gland(6)|biliary_tract(5)|bone(6)|breast(29)|central_nervous_system(12)|cervix(2)|endometrium(12)|haematopoietic_and_lymphoid_tissue(6)|kidney(8)|large_intestine(2768)|liver(15)|lung(39)|oesophagus(1)|ovary(12)|pancreas(27)|prostate(15)|salivary_gland(2)|skin(14)|small_intestine(34)|soft_tissue(55)|stomach(136)|thyroid(22)|upper_aerodigestive_tract(8)|urinary_tract(20)	3261		all_cancers(142;3.01e-27)|all_epithelial(76;2.3e-18)|all_hematologic(541;4.32e-09)|Ovarian(225;1.78e-06)|Lung NSC(167;0.000195)|Breast(839;0.000231)|all_lung(232;0.000247)|Colorectal(10;0.000355)|Prostate(80;0.00133)		OV - Ovarian serous cystadenocarcinoma(64;1.09e-113)|Epithelial(69;3.79e-112)|all cancers(49;1.67e-104)|BRCA - Breast invasive adenocarcinoma(61;0.00136)|COAD - Colon adenocarcinoma(37;0.00155)|Colorectal(14;0.00191)		CAAGCAGAAGTAAAACACCTCC	0.480		12	"""D, Mis, N, F, S"""		"""colorectal, pancreatic, desmoid, hepatoblastoma, glioma, other CNS"""	"""colorectal, pancreatic, desmoid, hepatoblastoma, glioma, other CNS"""			Turcot syndrome;Hereditary Desmoid Disease;Familial Adenomatous Polyposis	TSP Lung(16;0.13)			7	58	---	---	---	---					
NUTM2F	54754	broad.mit.edu	37	9	97080945	97080947	+	In_Frame_Del	DEL	AGA	AGA	-			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr9:97080945_97080947delAGA	ENST00000253262.4	-	7	2091_2093	c.2071_2073delTCT	c.(2071-2073)del	p.S691del	NUTM2F_ENST00000335456.7_Intron|NUTM2F_ENST00000341207.4_In_Frame_Del_p.S676del	NM_017561.1	NP_060031.1			NUT family member 2F									p.S557delS(1)									TGCTGGCAGGAGAAGGTGATGGG	0.611													6	9	---	---	---	---					
GNAS-AS1	0	broad.mit.edu	37	20	57405201	57405203	+	RNA	DEL	ACC	ACC	-			TCGA-HC-7819-01A-11D-2114-08	TCGA-HC-7819-11A-01D-2114-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	997549f6-8dde-4b4a-b477-609a535b301f	db9ab0ec-cd1f-4e69-935e-8e1665d07473	g.chr20:57405201_57405203delACC	ENST00000424094.2	-	0	819				GNAS-AS1_ENST00000598163.1_RNA	NR_002785.2																						ccaccaccataccaccaccacca	0.527													3	3	---	---	---	---