Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
SLC24A3	57419	broad.mit.edu	37	20	19566136	19566136	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr20:19566136C>T	ENST00000328041.6	+	6	757	c.560C>T	c.(559-561)gCg>gTg	p.A187V		NM_020689.3	NP_065740.2	Q9HC58	NCKX3_HUMAN	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	187						integral to membrane|plasma membrane	calcium, potassium:sodium antiporter activity|symporter activity			breast(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(10)|liver(1)|lung(10)|ovary(1)|pancreas(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(2)|urinary_tract(1)	39						GTGGGCTCAGCGGTATTCAAC	0.527000													10	288					0	0	0.000978159	0	0
OR1S2	219958	broad.mit.edu	37	11	57971223	57971223	+	Missense_Mutation	SNP	T	T	C			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr11:57971223T>C	ENST00000302592.6	-	1	430	c.431A>G	c.(430-432)aAc>aGc	p.N144S		NM_001004459.1	NP_001004459.1	Q8NGQ3	OR1S2_HUMAN	olfactory receptor, family 1, subfamily S, member 2	144					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			endometrium(11)|kidney(1)|large_intestine(4)|lung(23)|ovary(2)|skin(2)|stomach(2)|urinary_tract(1)	46		Breast(21;0.0589)				AGTTGTATAGTTCAGAGGGTG	0.463000													14	100					0	0	0.00244969	0	0
RGP1	9827	broad.mit.edu	37	9	35751280	35751280	+	Missense_Mutation	SNP	T	T	G			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr9:35751280T>G	ENST00000378078.4	+	6	646	c.505T>G	c.(505-507)Ttt>Gtt	p.F169V	RGP1_ENST00000456972.2_Missense_Mutation_p.F209V	NM_001080496.2	NP_001073965.2	Q92546	RGP1_HUMAN	RGP1 retrograde golgi transport homolog (S. cerevisiae)	169										cervix(1)|kidney(3)|large_intestine(1)|lung(4)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	14	all_epithelial(49;0.167)		Lung(28;0.00416)|LUSC - Lung squamous cell carcinoma(32;0.00418)|STAD - Stomach adenocarcinoma(86;0.194)			GGATGTCCGGTTTCCCCAGGA	0.512000													32	338					0	0	0.000692331	0	0
ST8SIA6	338596	broad.mit.edu	37	10	17365107	17365107	+	Missense_Mutation	SNP	T	T	C			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr10:17365107T>C	ENST00000377602.4	-	7	759	c.685A>G	c.(685-687)Aaa>Gaa	p.K229E		NM_001004470.1	NP_001004470.1	P61647	SIA8F_HUMAN	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	229					post-translational protein modification|protein N-linked glycosylation via asparagine	integral to Golgi membrane	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity			endometrium(3)|kidney(3)|large_intestine(4)|liver(1)|lung(24)|ovary(1)|skin(1)	37						AGATTTGTTTTACTGCCAACA	0.333000													25	50					0	0	0.00106085	0	0
PTPRG	5793	broad.mit.edu	37	3	62240850	62240850	+	Missense_Mutation	SNP	T	T	G			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr3:62240850T>G	ENST00000474889.1	+	16	2896	c.2519T>G	c.(2518-2520)cTc>cGc	p.L840R	PTPRG_ENST00000295874.10_Missense_Mutation_p.L811R	NM_002841.3	NP_002832.3	P23470	PTPRG_HUMAN	protein tyrosine phosphatase, receptor type, G	840					transmembrane receptor protein tyrosine kinase signaling pathway	integral to plasma membrane	identical protein binding|transmembrane receptor protein tyrosine phosphatase activity			NS(1)|breast(4)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(12)|liver(2)|lung(15)|ovary(7)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(2)	62				BRCA - Breast invasive adenocarcinoma(55;0.000376)|KIRC - Kidney renal clear cell carcinoma(10;0.0499)|Kidney(10;0.065)		ATCGGTGAGCTCTATTCTAAT	0.368000													34	60					0	0	0.000953801	0	0
KCNK5	8645	broad.mit.edu	37	6	39158873	39158873	+	Silent	SNP	G	G	A	rs144931567		TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr6:39158873G>A	ENST00000359534.3	-	5	1631	c.1293C>T	c.(1291-1293)gaC>gaT	p.D431D		NM_003740.3	NP_003731.1	O95279	KCNK5_HUMAN	potassium channel, subfamily K, member 5	431					excretion	integral to plasma membrane	potassium channel activity|voltage-gated ion channel activity	p.D431D(1)		central_nervous_system(1)|endometrium(2)|kidney(3)|large_intestine(6)|lung(4)|skin(3)	19						AGGTCTCCTCGTCTGAGAGGC	0.632000													4	38					0	0	0.00024832	0	0
ENPP1	5167	broad.mit.edu	37	6	132195457	132195457	+	Missense_Mutation	SNP	A	A	G			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr6:132195457A>G	ENST00000360971.2	+	16	1635	c.1615A>G	c.(1615-1617)Aat>Gat	p.N539D		NM_006208.2	NP_006199.2	P22413	ENPP1_HUMAN	ectonucleotide pyrophosphatase/phosphodiesterase 1	539	Phosphodiesterase.				3'-phosphoadenosine 5'-phosphosulfate metabolic process|biomineral tissue development|cellular phosphate ion homeostasis|cellular response to insulin stimulus|generation of precursor metabolites and energy|immune response|inorganic diphosphate transport|negative regulation of cell growth|negative regulation of fat cell differentiation|negative regulation of glucose import|negative regulation of glycogen biosynthetic process|negative regulation of insulin receptor signaling pathway|negative regulation of protein autophosphorylation|nucleoside triphosphate catabolic process|phosphate metabolic process|sequestering of triglyceride|water-soluble vitamin metabolic process	basolateral plasma membrane|cell surface|extracellular space|integral to membrane	ATP binding|insulin receptor binding|metal ion binding|nucleic acid binding|nucleoside-triphosphate diphosphatase activity|nucleotide diphosphatase activity|phosphodiesterase I activity|polysaccharide binding|protein homodimerization activity|scavenger receptor activity			autonomic_ganglia(1)|breast(2)|endometrium(1)|kidney(3)|large_intestine(8)|lung(22)|ovary(2)|prostate(2)|skin(3)|upper_aerodigestive_tract(2)	46	Breast(56;0.0505)			GBM - Glioblastoma multiforme(226;0.0216)|OV - Ovarian serous cystadenocarcinoma(155;0.022)	Amifostine(DB01143)|Ribavirin(DB00811)	TGGCTCTGACAATGTATTTTC	0.279000													39	67					0	0	0.00222228	0	0
SPOP	8405	broad.mit.edu	37	17	47696637	47696637	+	Missense_Mutation	SNP	A	A	G			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr17:47696637A>G	ENST00000393331.3	-	6	781	c.311T>C	c.(310-312)tTc>tCc	p.F104S	SPOP_ENST00000504102.1_Missense_Mutation_p.F104S|SPOP_ENST00000503676.1_Missense_Mutation_p.F104S|SPOP_ENST00000347630.2_Missense_Mutation_p.F104S|SPOP_ENST00000393328.2_Missense_Mutation_p.F104S	NM_001007226.1|NM_001007227.1	NP_001007227.1|NP_001007228.1	O43791	SPOP_HUMAN	speckle-type POZ protein	104	MATH.|Required for nuclear localization.				mRNA processing	nucleus	protein binding			endometrium(18)|kidney(1)|large_intestine(3)|liver(1)|lung(4)|ovary(3)|prostate(33)	63						CAGGATGGAGAATTTGAATTT	0.408000										Prostate(2;0.17)			44	73					0	0	0.00285205	0	0
PCDHB4	0	broad.mit.edu	37	5	140502262	140502262	+	Nonsense_Mutation	SNP	C	C	T			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr5:140502262C>T	ENST00000194152.1	+	1	682	c.682C>T	c.(682-684)Cga>Tga	p.R228*		NM_018938.2	NP_061761.1	Q9Y5E5	PCDB4_HUMAN		228	Cadherin 2.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	cytoplasm|integral to plasma membrane|intermediate filament cytoskeleton	calcium ion binding	p.R228*(1)		autonomic_ganglia(1)|breast(2)|endometrium(4)|kidney(2)|large_intestine(12)|lung(35)|ovary(1)|pancreas(1)|prostate(1)|skin(4)|upper_aerodigestive_tract(3)|urinary_tract(1)	67			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			GGTCATGGTTCGAATCCTGAT	0.542000													6	123					0	0	0.00116845	0	0
SLC22A16	85413	broad.mit.edu	37	6	110768172	110768172	+	Missense_Mutation	SNP	C	C	A			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr6:110768172C>A	ENST00000368919.3	-	3	621	c.555G>T	c.(553-555)ttG>ttT	p.L185F	SLC22A16_ENST00000330550.4_Missense_Mutation_p.L151F|SLC22A16_ENST00000439654.1_Missense_Mutation_p.L185F|SLC22A16_ENST00000456137.2_3'UTR	NM_033125.3	NP_149116.2	Q86VW1	S22AG_HUMAN	solute carrier family 22 (organic cation/carnitine transporter), member 16	185					acid secretion|cell differentiation|multicellular organismal development|single fertilization|sperm motility|spermatogenesis	integral to membrane	carnitine transporter activity			breast(1)|endometrium(1)|kidney(3)|large_intestine(6)|lung(16)|ovary(1)|prostate(1)|skin(4)|upper_aerodigestive_tract(1)	34		all_cancers(87;0.00221)|Acute lymphoblastic leukemia(125;2.27e-07)|all_hematologic(75;1.38e-05)|all_epithelial(87;0.0485)|Colorectal(196;0.101)		OV - Ovarian serous cystadenocarcinoma(136;0.0513)|Epithelial(106;0.0921)|all cancers(137;0.115)		TTGTGGCCCACAAGACCACCC	0.443000													13	21					1.61879e-10	6.28091e-10	0.00136819	1	0
HS3ST6	64711	broad.mit.edu	37	16	1961822	1961822	+	Silent	SNP	G	G	A			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr16:1961822G>A	ENST00000454677.2	-	2	914	c.849C>T	c.(847-849)ttC>ttT	p.F283F	HS3ST6_ENST00000293937.3_Silent_p.F266F|HS3ST6_ENST00000443547.1_Silent_p.F235F			C9JH64	C9JH64_HUMAN	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	235										endometrium(2)|lung(2)	4						TCAGGCCCAGGAAGTCCTGCA	0.667000													13	143					0	0	0.00244969	0	0
CNOT2	4848	broad.mit.edu	37	12	70723332	70723332	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr12:70723332C>T	ENST00000229195.3	+	5	947	c.368C>T	c.(367-369)aCg>aTg	p.T123M	CNOT2_ENST00000418359.3_Missense_Mutation_p.T123M|CNOT2_ENST00000548230.1_3'UTR	NM_014515.5	NP_055330.1	Q9NZN8	CNOT2_HUMAN	CCR4-NOT transcription complex, subunit 2	123					nuclear-transcribed mRNA poly(A) tail shortening|regulation of transcription from RNA polymerase II promoter	cytosol|nucleus	protein binding|RNA polymerase II transcription cofactor activity			cervix(1)|endometrium(2)|kidney(2)|large_intestine(2)|lung(10)|pancreas(2)|urinary_tract(1)	20	Renal(347;0.236)		GBM - Glioblastoma multiforme(1;4.77e-09)|Lung(24;0.000636)|OV - Ovarian serous cystadenocarcinoma(12;0.00243)|STAD - Stomach adenocarcinoma(21;0.0118)			TCACTTCACACGCCTCCATCT	0.398000													24	50					0	0	0.000878237	0	0
FBN3	84467	broad.mit.edu	37	19	8140171	8140171	+	Missense_Mutation	SNP	A	A	C			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr19:8140171A>C	ENST00000600128.1	-	60	7992	c.7578T>G	c.(7576-7578)tgT>tgG	p.C2526W	FBN3_ENST00000601739.1_Missense_Mutation_p.C2526W|FBN3_ENST00000270509.2_Missense_Mutation_p.C2526W			Q75N90	FBN3_HUMAN	fibrillin 3	2526	EGF-like 41; calcium-binding.					proteinaceous extracellular matrix	calcium ion binding|extracellular matrix structural constituent			NS(1)|breast(9)|central_nervous_system(2)|cervix(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(2)|kidney(8)|large_intestine(15)|lung(53)|ovary(7)|pancreas(2)|prostate(3)|skin(10)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(2)	132						CTGTACCTTCACAGCCATGGC	0.602000													22	40					0	0	0.00229938	0	0
SLC51A	200931	broad.mit.edu	37	3	195959365	195959365	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr3:195959365C>T	ENST00000296327.5	+	8	1065	c.856C>T	c.(856-858)Cct>Tct	p.P286S	PCYT1A_ENST00000419333.1_Intron	NM_152672.5	NP_689885.4			solute carrier family 51, alpha subunit																		TGCTTGTTCGCCTCCCTATTC	0.552000													7	86					0	0	0.000157383	0	0
ANKRD30A	91074	broad.mit.edu	37	10	37508447	37508447	+	Nonsense_Mutation	SNP	T	T	G			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr10:37508447T>G	ENST00000374660.1	+	40	4095	c.3996T>G	c.(3994-3996)taT>taG	p.Y1332*	ANKRD30A_ENST00000602533.1_Nonsense_Mutation_p.Y1213*|ANKRD30A_ENST00000361713.1_Nonsense_Mutation_p.Y1213*			Q9BXX3	AN30A_HUMAN	ankyrin repeat domain 30A	1269						nucleus	DNA binding|sequence-specific DNA binding transcription factor activity			NS(1)|breast(8)|endometrium(14)|kidney(21)|large_intestine(13)|lung(70)|ovary(8)|pancreas(1)|prostate(3)|skin(15)|stomach(1)|urinary_tract(3)	158						ATCTCAATTATGCAGGAGATG	0.373000													3	36					0	0	6.4e-05	0	0
NRCAM	4897	broad.mit.edu	37	7	107880413	107880413	+	Silent	SNP	T	T	C			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr7:107880413T>C	ENST00000379028.3	-	4	566	c.96A>G	c.(94-96)gtA>gtG	p.V32V	NRCAM_ENST00000379022.4_Silent_p.V32V|NRCAM_ENST00000379024.4_Silent_p.V32V|NRCAM_ENST00000425651.2_Silent_p.V32V|NRCAM_ENST00000351718.4_Silent_p.V32V|NRCAM_ENST00000413765.2_Silent_p.V32V			Q92823	NRCAM_HUMAN	neuronal cell adhesion molecule	32					angiogenesis|axon guidance|axonal fasciculation|cell-cell adhesion|central nervous system development|clustering of voltage-gated sodium channels|neuron migration|positive regulation of neuron differentiation|regulation of axon extension|synapse assembly	external side of plasma membrane|integral to plasma membrane	ankyrin binding			breast(4)|cervix(1)|endometrium(1)|kidney(2)|large_intestine(8)|liver(1)|lung(36)|ovary(3)|prostate(2)|skin(3)|upper_aerodigestive_tract(4)	65						GATCAAGAGGTACTTCCAGTG	0.458000													16	152					0	0	0.00074312	0	0
NSRP1	84081	broad.mit.edu	37	17	28511696	28511696	+	Missense_Mutation	SNP	A	A	G			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr17:28511696A>G	ENST00000247026.5	+	7	744	c.681A>G	c.(679-681)atA>atG	p.I227M	NSRP1_ENST00000540900.3_3'UTR	NM_001261467.1|NM_032141.3	NP_001248396.1|NP_115517.1	Q9H0G5	NSRP1_HUMAN	nuclear speckle splicing regulatory protein 1	227					developmental process|nucleocytoplasmic transport|regulation of alternative nuclear mRNA splicing, via spliceosome	nuclear speck|ribonucleoprotein complex	mRNA binding|protein binding			autonomic_ganglia(1)|endometrium(2)|large_intestine(3)|lung(6)|ovary(1)|pancreas(1)	14						AAAACAGAATACCACAAGAGA	0.368000													3	51					0	0	6.4e-05	0	0
WNK1	65125	broad.mit.edu	37	12	966384	966384	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr12:966384G>A	ENST00000537687.1	+	5	2012	c.1369G>A	c.(1369-1371)Gaa>Aaa	p.E457K	WNK1_ENST00000530271.2_Missense_Mutation_p.E457K|WNK1_ENST00000540360.1_3'UTR|WNK1_ENST00000315939.6_Missense_Mutation_p.E457K|WNK1_ENST00000340908.4_Missense_Mutation_p.E50K|WNK1_ENST00000535572.1_Missense_Mutation_p.E457K	NM_001184985.1|NM_213655.4	NP_001171914.1|NP_998820.3	Q9H4A3	WNK1_HUMAN	WNK lysine deficient protein kinase 1	457	Protein kinase.				intracellular protein kinase cascade|ion transport|neuron development	cytoplasm	ATP binding|protein binding|protein kinase inhibitor activity|protein serine/threonine kinase activity			breast(7)|central_nervous_system(1)|endometrium(3)|kidney(6)|large_intestine(15)|lung(43)|ovary(6)|prostate(3)|skin(7)|stomach(8)|upper_aerodigestive_tract(3)|urinary_tract(2)	104	all_cancers(10;0.00611)|all_epithelial(11;0.00825)|all_lung(10;0.0331)|Ovarian(42;0.0512)|Lung NSC(10;0.0632)		Epithelial(1;1.74e-08)|all cancers(1;7.04e-08)|OV - Ovarian serous cystadenocarcinoma(31;0.000423)|BRCA - Breast invasive adenocarcinoma(9;0.0149)|Colorectal(1;0.0197)			GGAAATTATTGAAGGATGCAT	0.373000													23	29					0	0	0.000878237	0	0
AIFM2	84883	broad.mit.edu	37	10	71877572	71877572	+	Silent	SNP	C	C	A			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr10:71877572C>A	ENST00000307864.1	-	6	825	c.612G>T	c.(610-612)ctG>ctT	p.L204L	AIFM2_ENST00000373248.1_Silent_p.L204L|AIFM2_ENST00000482166.1_5'UTR	NM_001198696.1|NM_032797.5	NP_001185625.1|NP_116186.1	Q9BRQ8	AIFM2_HUMAN	apoptosis-inducing factor, mitochondrion-associated, 2	204					apoptotic mitochondrial changes|chromosome condensation|induction of apoptosis	cytosol|integral to membrane|mitochondrial outer membrane	DNA binding|electron-transferring-flavoprotein dehydrogenase activity|flavin adenine dinucleotide binding			breast(2)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(2)|lung(3)|prostate(1)|skin(2)|urinary_tract(2)	16						ACGTACTCAGCAGCAGCTGCA	0.637000													8	64					0.000442599	0.00168361	0.000442599	1	0
FADS3	3995	broad.mit.edu	37	11	61641315	61641315	+	Missense_Mutation	SNP	T	T	C			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr11:61641315T>C	ENST00000278829.2	-	12	1461	c.1309A>G	c.(1309-1311)Atc>Gtc	p.I437V	FADS3_ENST00000525588.1_Missense_Mutation_p.I409V|FADS3_ENST00000527697.1_Missense_Mutation_p.I322V|FADS3_ENST00000540820.1_3'UTR	NM_021727.3	NP_068373.1	Q9Y5Q0	FADS3_HUMAN	fatty acid desaturase 3	437					electron transport chain|transport|unsaturated fatty acid biosynthetic process	endoplasmic reticulum membrane|integral to membrane|membrane fraction	heme binding|oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water			central_nervous_system(1)|endometrium(1)|large_intestine(3)|lung(4)|ovary(1)|pancreas(1)|prostate(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	15						TCCAGCCAGATGTCACCAGAC	0.622000													3	28					0	0	0.00024832	0	0
KIN	22944	broad.mit.edu	37	10	7822139	7822139	+	Missense_Mutation	SNP	T	T	G			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr10:7822139T>G	ENST00000379562.3	-	4	303	c.256A>C	c.(256-258)Act>Cct	p.T86P	KIN_ENST00000535925.1_Missense_Mutation_p.T86P|KIN_ENST00000543003.1_5'UTR			O60870	KIN17_HUMAN	KIN, antigenic determinant of recA protein homolog (mouse)	86					DNA recombination|DNA repair|DNA replication|interspecies interaction between organisms|mRNA processing	cytoplasm|nuclear matrix	double-stranded DNA binding|RNA binding|zinc ion binding			endometrium(1)|kidney(2)|large_intestine(3)|lung(9)|ovary(1)|pancreas(1)|skin(2)	19						ACCCTTTTAGTGCCTGAGAAC	0.388000													31	78					0	0	0.00209593	0	0
CDH3	1001	broad.mit.edu	37	16	68732283	68732283	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr16:68732283G>A	ENST00000264012.4	+	16	3014	c.2470G>A	c.(2470-2472)Ggt>Agt	p.G824S	CDH3_ENST00000581171.1_Missense_Mutation_p.G769S|CDH3_ENST00000429102.2_3'UTR	NM_001793.4	NP_001784.2	P22223	CADH3_HUMAN	cadherin 3, type 1, P-cadherin (placental)	824					adherens junction organization|cell junction assembly|homophilic cell adhesion|response to stimulus|visual perception	integral to membrane	calcium ion binding	p.?(2)		NS(1)|breast(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(7)|lung(4)|ovary(3)|skin(1)|urinary_tract(1)	25		Ovarian(137;0.0564)		OV - Ovarian serous cystadenocarcinoma(108;0.000782)|Epithelial(162;0.0054)|all cancers(182;0.0384)		AGACATGTACGGTGGCGGGGA	0.617000													40	58					0	0	0.00285205	0	0
HTT	3064	broad.mit.edu	37	4	3176835	3176835	+	Splice_Site	SNP	G	G	C			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr4:3176835G>C	ENST00000355072.5	+	33	4552		c.e33+1			NM_002111.6	NP_002102.4	P42858	HD_HUMAN	huntingtin						establishment of mitotic spindle orientation|Golgi organization|retrograde vesicle-mediated transport, Golgi to ER|vesicle transport along microtubule	autophagic vacuole|axon|cytoplasmic vesicle membrane|cytosol|dendrite|endoplasmic reticulum|Golgi apparatus|late endosome|membrane fraction|nucleus|protein complex	beta-tubulin binding|dynactin binding|dynein intermediate chain binding|p53 binding|transcription factor binding			breast(1)|cervix(2)|endometrium(14)|kidney(5)|large_intestine(23)|lung(28)|ovary(4)|prostate(2)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(1)	87		all_epithelial(65;0.18)		UCEC - Uterine corpus endometrioid carcinoma (64;0.187)		TTCAGATCAGGTTTGTCACTT	0.388000													10	117					0	0	0.000442599	0	0
ZNF142	7701	broad.mit.edu	37	2	219505430	219505430	+	Missense_Mutation	SNP	G	G	C			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr2:219505430G>C	ENST00000411696.2	-	8	5330	c.4551C>G	c.(4549-4551)tgC>tgG	p.C1517W	ZNF142_ENST00000449707.1_Missense_Mutation_p.C1517W			P52746	ZN142_HUMAN	zinc finger protein 142	1517					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(7)|endometrium(7)|large_intestine(5)|lung(12)|ovary(2)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	38		Renal(207;0.0474)		Epithelial(149;5.21e-07)|all cancers(144;0.000106)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00948)		TGACCCACTTGCACTTGTAGC	0.493000													16	29					0	0	0.000566183	0	0
POM121L9P	0	broad.mit.edu	37	22	24659578	24659578	+	RNA	SNP	A	A	G			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr22:24659578A>G	ENST00000414583.2	+	0	3103					NR_003714.1																						TGCGCAGGCCAACACTCACTG	0.617000													4	23					0	0	0.000602214	0	0
NCAPG2	54892	broad.mit.edu	37	7	158443616	158443616	+	Nonsense_Mutation	SNP	G	G	A			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr7:158443616G>A	ENST00000409339.3	-	24	3096	c.2983C>T	c.(2983-2985)Cag>Tag	p.Q995*	NCAPG2_ENST00000356309.3_Nonsense_Mutation_p.Q995*|NCAPG2_ENST00000449727.2_Nonsense_Mutation_p.Q995*|NCAPG2_ENST00000275830.10_Intron|NCAPG2_ENST00000541468.1_Intron|NCAPG2_ENST00000409423.1_Nonsense_Mutation_p.Q995*			Q86XI2	CNDG2_HUMAN	non-SMC condensin II complex, subunit G2	995					cell division|chromosome condensation|mitosis	nucleus	methylated histone residue binding			NS(1)|breast(1)|endometrium(5)|kidney(5)|large_intestine(7)|liver(1)|lung(15)|ovary(1)|pancreas(1)|prostate(1)|skin(1)	39	Ovarian(565;0.152)	all_cancers(7;3.44e-11)|all_epithelial(9;3.05e-05)|all_hematologic(28;0.014)	OV - Ovarian serous cystadenocarcinoma(82;0.00174)	UCEC - Uterine corpus endometrioid carcinoma (81;0.187)|STAD - Stomach adenocarcinoma(7;0.18)		TGCCGAGACTGAACAGCAGTA	0.463000													12	98					0	0	0.00136819	0	0
TP53BP1	7158	broad.mit.edu	37	15	43748753	43748753	+	Nonsense_Mutation	SNP	T	T	A			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr15:43748753T>A	ENST00000263801.3	-	12	2290	c.2038A>T	c.(2038-2040)Aaa>Taa	p.K680*	TP53BP1_ENST00000450115.2_Nonsense_Mutation_p.K685*|TP53BP1_ENST00000382039.3_Nonsense_Mutation_p.K685*|TP53BP1_ENST00000382044.4_Nonsense_Mutation_p.K685*	NM_005657.2	NP_005648.1	Q12888	TP53B_HUMAN	tumor protein p53 binding protein 1	680					double-strand break repair via homologous recombination|positive regulation of transcription from RNA polymerase II promoter	condensed chromosome kinetochore|cytoplasm|nucleoplasm	p53 binding|RNA polymerase II activating transcription factor binding|RNA polymerase II transcription cofactor activity			breast(4)|endometrium(5)|kidney(7)|large_intestine(22)|lung(13)|ovary(4)|pancreas(2)|prostate(1)|skin(10)|upper_aerodigestive_tract(1)|urinary_tract(3)	72		all_cancers(109;6.94e-11)|all_epithelial(112;2.69e-09)|Lung NSC(122;7.86e-07)|all_lung(180;7.84e-06)|Melanoma(134;0.0728)		GBM - Glioblastoma multiforme(94;1.59e-06)		TTTTCTTCTTTGAGTTCCTCT	0.443000								Other conserved DNA damage response genes					10	127					0	0	0.000442599	0	0
C2orf44	80304	broad.mit.edu	37	2	24261454	24261454	+	Missense_Mutation	SNP	C	C	G			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr2:24261454C>G	ENST00000295148.4	-	2	968	c.911G>C	c.(910-912)aGa>aCa	p.R304T	C2orf44_ENST00000406895.3_Missense_Mutation_p.R304T	NM_025203.2	NP_079479.1	Q9H6R7	CB044_HUMAN	chromosome 2 open reading frame 44	304							protein binding		C2orf44/ALK(2)	breast(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(6)|lung(7)|ovary(1)|pancreas(1)|skin(2)|urinary_tract(1)	24	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)					GTCCTTTTTTCTTAGACAAAT	0.373000			T	ALK	NSCLC								13	54					0	0	0.00136819	0	0
UNC13D	201294	broad.mit.edu	37	17	73838576	73838576	+	Missense_Mutation	SNP	C	C	G			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr17:73838576C>G	ENST00000207549.4	-	6	886	c.507G>C	c.(505-507)gaG>gaC	p.E169D	UNC13D_ENST00000412096.2_Missense_Mutation_p.E169D|UNC13D_ENST00000587504.1_5'UTR	NM_199242.2	NP_954712.1	Q70J99	UN13D_HUMAN	unc-13 homolog D (C. elegans)	169	C2 1.				positive regulation of exocytosis|regulation of mast cell degranulation	exocytic vesicle|late endosome|lysosome|membrane|recycling endosome	protein binding			central_nervous_system(1)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(4)|lung(9)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	29			all cancers(21;2.11e-06)|Epithelial(20;2.32e-06)|BRCA - Breast invasive adenocarcinoma(9;0.000618)|LUSC - Lung squamous cell carcinoma(166;0.154)			TGCGGTGGGTCTCCTCCTCGG	0.667000									Familial Hemophagocytic Lymphohistiocytosis				12	69					0	0	0.00136819	0	0
GXYLT2	727936	broad.mit.edu	37	3	73016753	73016753	+	Silent	SNP	C	C	T			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr3:73016753C>T	ENST00000389617.4	+	6	1193	c.1032C>T	c.(1030-1032)taC>taT	p.Y344Y		NM_001080393.1	NP_001073862.1	A0PJZ3	GXLT2_HUMAN	glucoside xylosyltransferase 2	344					O-glycan processing	integral to membrane	UDP-xylosyltransferase activity	p.Y344Y(1)		NS(1)|endometrium(2)|kidney(1)|large_intestine(4)|lung(6)|upper_aerodigestive_tract(1)|urinary_tract(3)	18						ACTGCATGTACGGAAGCAACT	0.498000													5	19					0	0	0.000602214	0	0
MADD	8567	broad.mit.edu	37	11	47350634	47350634	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr11:47350634C>T	ENST00000342922.4	+	33	5057	c.4700C>T	c.(4699-4701)tCg>tTg	p.S1567L	MADD_ENST00000407859.3_Missense_Mutation_p.S1544L|MADD_ENST00000406482.1_3'UTR|MADD_ENST00000402799.1_Missense_Mutation_p.S1524L|MADD_ENST00000395336.3_3'UTR|MADD_ENST00000395344.3_Missense_Mutation_p.S1520L|MADD_ENST00000349238.3_Missense_Mutation_p.S1587L|MADD_ENST00000311027.5_Missense_Mutation_p.S1626L|MADD_ENST00000402192.2_Missense_Mutation_p.S1566L	NM_130470.2	NP_569826.2	Q8WXG6	MADD_HUMAN	MAP-kinase activating death domain	1626					activation of MAPK activity|apoptosis|cell surface receptor linked signaling pathway|regulation of apoptosis|regulation of cell cycle	cytoplasm|integral to membrane|plasma membrane	death receptor binding|protein kinase activator activity|Rab guanyl-nucleotide exchange factor activity			breast(7)|central_nervous_system(2)|endometrium(9)|kidney(3)|large_intestine(19)|lung(26)|ovary(6)|prostate(2)|skin(5)|upper_aerodigestive_tract(3)|urinary_tract(2)	84				Lung(87;0.182)		TGTCTCTTCTCGTACGTGGCT	0.557000													80	121					0	0	0.000781405	0	0
ZNF827	152485	broad.mit.edu	37	4	146823855	146823855	+	Missense_Mutation	SNP	T	T	G			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr4:146823855T>G	ENST00000508784.1	-	2	783	c.556A>C	c.(556-558)Agt>Cgt	p.S186R	ZNF827_ENST00000379448.4_Missense_Mutation_p.S186R|ZNF827_ENST00000513320.1_Intron			Q17R98	ZN827_HUMAN	zinc finger protein 827	186					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(1)|breast(2)|cervix(1)|endometrium(3)|kidney(2)|large_intestine(13)|lung(18)|prostate(4)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	48	all_hematologic(180;0.151)					AAACGGTTACTTGGAGTGTAT	0.517000													6	83					0	0	0.00116845	0	0
HOXB13	10481	broad.mit.edu	37	17	46805442	46805442	+	Missense_Mutation	SNP	A	A	C			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr17:46805442A>C	ENST00000290295.7	-	1	1098	c.514T>G	c.(514-516)Tgg>Ggg	p.W172G		NM_006361.5	NP_006352.2	Q92826	HXB13_HUMAN	homeobox B13	172					angiogenesis|epidermis development|response to wounding		sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			endometrium(2)|kidney(2)|lung(6)|prostate(1)	11						GCGAGAGCCCAAGACTGGTAA	0.567000													30	41					0	0	0.00178596	0	0
LCE2D	353141	broad.mit.edu	37	1	152636615	152636615	+	Frame_Shift_Del	DEL	C	C	-			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr1:152636615delC	ENST00000368784.1	+	2	89	c.34delC	c.(34-36)ccfs	p.P14fs		NM_178430.2	NP_848517.1	Q5TA82	LCE2D_HUMAN	late cornified envelope 2D	14	Cys-rich.				keratinization					large_intestine(1)|lung(7)|prostate(2)	10	Hepatocellular(266;0.0877)|all_hematologic(923;0.127)|Melanoma(130;0.242)		LUSC - Lung squamous cell carcinoma(543;0.206)			GCAGTGCCAGCCCCCTCCCAA	0.493													15	145	---	---	---	---					
AC016995.3	0	broad.mit.edu	37	2	38710012	38710013	+	RNA	INS	-	-	A	rs71402229		TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr2:38710012_38710013insA	ENST00000417039.1	-	0	696																											CTTACTTCTTtaaaaaataaat	0.252													4	5	---	---	---	---					
CHDH	55349	broad.mit.edu	37	3	53857978	53857992	+	In_Frame_Del	DEL	CCAGGGCTCCCCGTG	CCAGGGCTCCCCGTG	-	rs61746180	by1000genomes	TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr3:53857978_53857992delCCAGGGCTCCCCGTG	ENST00000315251.5	-	3	481_495	c.44_58delCACGGGGAGCCCTGG	c.(43-60)ggg>g	p.ARGALG15del		NM_018397.4	NP_060867.2	Q8NE62	CHDH_HUMAN	choline dehydrogenase	15					alcohol metabolic process		choline dehydrogenase activity|flavin adenine dinucleotide binding			NS(1)|breast(1)|central_nervous_system(2)|cervix(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(4)|ovary(2)|prostate(1)	17		Hepatocellular(537;0.152)		BRCA - Breast invasive adenocarcinoma(193;0.000158)|KIRC - Kidney renal clear cell carcinoma(284;0.00588)|Kidney(284;0.00673)|OV - Ovarian serous cystadenocarcinoma(275;0.118)	Choline(DB00122)	TGCTGCTGCCCCAGGGCTCCCCGTGCCAGGGCTCC	0.665													3	4	---	---	---	---					
SRSF1	6426	broad.mit.edu	37	17	56083248	56083249	+	Frame_Shift_Ins	INS	-	-	A			TCGA-G9-6338-01A-12D-1961-08	TCGA-G9-6338-10A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c9708a4f-76b5-4eb5-9831-a1f069096578	e152fd51-11d4-46c4-b803-1b79e8f6cf18	g.chr17:56083248_56083249insA	ENST00000582730.2	-	3	588_589	c.465_466insT	c.(463-468)gagcacfs	p.EH155fs	SRSF1_ENST00000584773.1_Frame_Shift_Ins_p.EH155fs|SRSF1_ENST00000585096.1_Intron|SRSF1_ENST00000258962.4_Frame_Shift_Ins_p.EH155fs	NM_001078166.1	NP_001071634.1	Q07955	SRSF1_HUMAN	serine/arginine-rich splicing factor 1	155	RRM 2.				mRNA 3'-end processing|mRNA export from nucleus|nuclear mRNA 5'-splice site recognition|termination of RNA polymerase II transcription	catalytic step 2 spliceosome|cytoplasm|nuclear speck	nucleotide binding|RNA binding			breast(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(1)|lung(7)|ovary(2)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	24						ACACCAGTGCCATCTCGGTAAA	0.426													22	50	---	---	---	---