Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
WASH3P	374666	broad.mit.edu	37	15	102515299	102515299	+	RNA	SNP	G	G	A			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr15:102515299G>A	ENST00000557932.1	+	0	1145																		p.G374S(10)		central_nervous_system(1)|endometrium(6)|kidney(11)|prostate(5)|stomach(1)|urinary_tract(1)	25						TGGGGGCATCGGCAAGGCCAA	0.652000													6	9					0	0	1	0	0
DNAH1	25981	broad.mit.edu	37	3	52406913	52406913	+	Splice_Site	SNP	C	C	T			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr3:52406913C>T	ENST00000420323.2	+	44	7090	c.6827_splice	c.e44-1	p.R2277_splice		NM_015512.4	NP_056327.4	Q9P2D7	DYH1_HUMAN	dynein, axonemal, heavy chain 1	2277	AAA 3 (By similarity).				ciliary or flagellar motility|microtubule-based movement|response to mechanical stimulus	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity			cervix(2)|endometrium(18)|kidney(6)|large_intestine(3)|lung(31)|prostate(1)|urinary_tract(1)	62				BRCA - Breast invasive adenocarcinoma(193;2.02e-05)|OV - Ovarian serous cystadenocarcinoma(275;0.000207)|Kidney(197;0.0022)|KIRC - Kidney renal clear cell carcinoma(197;0.00245)		TCCCCTCAGGCGGAAGGGTGT	0.617000													21	57					0	0	1	0	0
OR8H3	390152	broad.mit.edu	37	11	55890333	55890333	+	Missense_Mutation	SNP	C	C	T			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr11:55890333C>T	ENST00000313472.3	+	1	485	c.485C>T	c.(484-486)tCc>tTc	p.S162F		NM_001005201.1	NP_001005201.1	Q8N146	OR8H3_HUMAN	olfactory receptor, family 8, subfamily H, member 3	162					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity	p.S162Y(1)|p.S162F(1)		endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(30)|ovary(2)|prostate(1)|skin(3)|stomach(1)	42	Esophageal squamous(21;0.00693)					AATGTGGTTTCCATGAGCAGA	0.438000													41	100					0	0	1	0	0
TRAFD1	10906	broad.mit.edu	37	12	112578648	112578648	+	Missense_Mutation	SNP	C	C	T			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr12:112578648C>T	ENST00000257604.5	+	5	880	c.263C>T	c.(262-264)gCt>gTt	p.A88V	TRAFD1_ENST00000412615.2_Missense_Mutation_p.A88V	NM_001143906.1	NP_001137378.1	O14545	TRAD1_HUMAN	TRAF-type zinc finger domain containing 1	88					negative regulation of innate immune response	intracellular	protein binding|zinc ion binding			kidney(5)|large_intestine(3)|lung(5)|prostate(1)|skin(1)|upper_aerodigestive_tract(2)	17						TTGCGGCTTGCTGTCTGCCAG	0.468000													4	83					0	0	1	0	0
KMT2C	58508	broad.mit.edu	37	7	151945602	151945602	+	Silent	SNP	G	G	A			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr7:151945602G>A	ENST00000355193.2	-	14	2135	c.1917C>T	c.(1915-1917)ggC>ggT	p.G639G	KMT2C_ENST00000262189.6_Silent_p.G639G					lysine (K)-specific methyltransferase 2C																		TTTGATCTTCGCCACAAATAT	0.373000													4	68					0	0	1	0	0
MDGA1	266727	broad.mit.edu	37	6	37622620	37622620	+	Missense_Mutation	SNP	C	C	T			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr6:37622620C>T	ENST00000434837.2	-	5	1846	c.668G>A	c.(667-669)gGc>gAc	p.G223D	MDGA1_ENST00000505425.1_Missense_Mutation_p.G223D|MDGA1_ENST00000297153.7_Missense_Mutation_p.G223D	NM_153487.3	NP_705691.1	Q8NFP4	MDGA1_HUMAN	MAM domain containing glycosylphosphatidylinositol anchor 1	223	Ig-like 2.				brain development|neuron migration|spinal cord association neuron differentiation	anchored to plasma membrane		p.G223D(1)		central_nervous_system(2)|endometrium(6)|kidney(3)|large_intestine(12)|lung(11)|prostate(1)|skin(2)|urinary_tract(1)	38						GTCTGGGATGCCGCACACGTT	0.597000													4	120					0	0	1	0	0
PDPN	10630	broad.mit.edu	37	1	13910449	13910449	+	Missense_Mutation	SNP	G	G	C			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr1:13910449G>C	ENST00000294489.6	+	1	490	c.149G>C	c.(148-150)tGg>tCg	p.W50S	PDPN_ENST00000376057.4_Missense_Mutation_p.W50S			Q86YL7	PDPN_HUMAN	podoplanin	0					cell morphogenesis|lymphangiogenesis|regulation of cell shape	filopodium membrane|integral to plasma membrane|lamellipodium membrane|microvillus membrane|ruffle membrane				endometrium(3)|kidney(2)|large_intestine(2)|liver(2)|lung(3)|ovary(2)|skin(1)|upper_aerodigestive_tract(1)	16	Ovarian(185;0.249)	all_lung(284;2.29e-05)|Lung NSC(185;4.37e-05)|Renal(390;0.000147)|Breast(348;0.000162)|Colorectal(325;0.00058)|Ovarian(437;0.00965)|Hepatocellular(190;0.0245)|Myeloproliferative disorder(586;0.0255)	GBM - Glioblastoma multiforme(2;0.00182)	UCEC - Uterine corpus endometrioid carcinoma (279;0.00969)|Colorectal(212;4.48e-06)|COAD - Colon adenocarcinoma(227;0.000194)|BRCA - Breast invasive adenocarcinoma(304;0.000347)|Kidney(185;0.00087)|KIRC - Kidney renal clear cell carcinoma(229;0.0027)|STAD - Stomach adenocarcinoma(313;0.00802)|READ - Rectum adenocarcinoma(331;0.0678)		CTGGGCCTGTGGCCGCGGTGC	0.657000													7	11					0	0	1	0	0
RGS14	10636	broad.mit.edu	37	5	176798390	176798390	+	Missense_Mutation	SNP	G	G	A			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr5:176798390G>A	ENST00000408923.3	+	13	1564	c.1376G>A	c.(1375-1377)cGc>cAc	p.R459H	RGS14_ENST00000506944.1_3'UTR	NM_006480.4	NP_006471.2	O43566	RGS14_HUMAN	regulator of G-protein signaling 14	459					chromosome segregation|long-term memory|long-term synaptic potentiation|negative regulation of ERK1 and ERK2 cascade|negative regulation of MAP kinase activity|negative regulation of synaptic plasticity|nucleocytoplasmic transport|platelet-derived growth factor receptor signaling pathway|positive regulation of neurogenesis|regulation of DNA-dependent transcription in response to stress|regulation of G-protein coupled receptor protein signaling pathway|response to oxidative stress|spindle organization|visual learning|zygote asymmetric cell division	cell junction|centrosome|dendritic spine|microtubule|PML body|postsynaptic density|postsynaptic membrane|spindle pole	GDP-dissociation inhibitor activity|GTPase activator activity|microtubule binding|receptor signaling complex scaffold activity|receptor signaling protein activity			breast(1)|central_nervous_system(1)|endometrium(1)|large_intestine(2)|lung(3)|skin(3)|upper_aerodigestive_tract(1)	12	all_cancers(89;2.04e-05)|Renal(175;0.000269)|Lung NSC(126;0.000832)|all_lung(126;0.00152)	all_neural(177;0.00409)|Medulloblastoma(196;0.00498)|all_hematologic(541;0.21)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)			TCTCCCTGCCGCAGCCAGGTG	0.607000													4	64					0	0	1	0	0
KIF20A	10112	broad.mit.edu	37	5	137518596	137518596	+	Missense_Mutation	SNP	G	G	A			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr5:137518596G>A	ENST00000394894.3	+	7	975	c.749G>A	c.(748-750)cGg>cAg	p.R250Q	KIF20A_ENST00000508792.1_Missense_Mutation_p.R232Q	NM_005733.2	NP_005724.1	O95235	KI20A_HUMAN	kinesin family member 20A	250	Kinesin-motor.				cytokinesis|M phase of mitotic cell cycle|microtubule-based movement|protein transport|vesicle-mediated transport	Golgi apparatus|microtubule|nucleoplasm	ATP binding|microtubule motor activity|protein binding|transporter activity			endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(3)|liver(2)|lung(9)|prostate(2)|upper_aerodigestive_tract(1)	27			KIRC - Kidney renal clear cell carcinoma(527;0.0101)|Kidney(363;0.0109)			ATCGAAAGTCGGATAGGTACC	0.537000													3	38					0	0	1	0	0
FIG4	9896	broad.mit.edu	37	6	110036319	110036319	+	Silent	SNP	A	A	G			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr6:110036319A>G	ENST00000230124.3	+	2	229	c.105A>G	c.(103-105)aaA>aaG	p.K35K	FIG4_ENST00000441478.2_5'UTR	NM_014845.5	NP_055660.1	Q92562	FIG4_HUMAN	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)	35					cell death	endosome membrane	protein binding			central_nervous_system(2)|cervix(1)|endometrium(4)|kidney(4)|large_intestine(3)|lung(14)|ovary(2)|prostate(2)	32		all_cancers(87;8.63e-07)|Acute lymphoblastic leukemia(125;2.66e-08)|all_hematologic(75;1.13e-06)|all_epithelial(87;0.000124)|all_lung(197;0.0187)|Colorectal(196;0.0492)|Lung SC(18;0.0548)		OV - Ovarian serous cystadenocarcinoma(136;0.0355)|Epithelial(106;0.038)|all cancers(137;0.0425)|BRCA - Breast invasive adenocarcinoma(108;0.079)		CAGAAACGAAATATCGTGTCT	0.323000													24	31					0	0	1	0	0
KRTAP1-5	83895	broad.mit.edu	37	17	39183145	39183145	+	Missense_Mutation	SNP	A	A	G			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr17:39183145A>G	ENST00000361883.5	-	1	309	c.263T>C	c.(262-264)aTc>aCc	p.I88T		NM_031957.1	NP_114163.1	Q9BYS1	KRA15_HUMAN	keratin associated protein 1-5	88	15 X 5 AA repeats of C-C-[QEPVRC]- [TPIVLE]-[SRHVP].					keratin filament		p.I88T(11)		central_nervous_system(1)|endometrium(2)|kidney(1)|lung(9)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(2)	17		Breast(137;0.00043)	STAD - Stomach adenocarcinoma(17;0.000371)			GCAGGAGCTGATCTGGCAGCA	0.632000													3	48					0	0	1	0	0
TCTEX1D4	343521	broad.mit.edu	37	1	45272252	45272252	+	Frame_Shift_Del	DEL	C	C	-			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr1:45272252delC	ENST00000372200.1	-	2	597	c.89delG	c.(88-90)gcfs	p.G30fs	TCTEX1D4_ENST00000339355.2_Frame_Shift_Del_p.G30fs	NM_001013632.2	NP_001013654.1	Q5JR98	TC1D4_HUMAN	Tctex1 domain containing 4	30										pancreas(1)	1	Acute lymphoblastic leukemia(166;0.155)					GGGCAGGCAGCCTCGGGGCCG	0.731													2	4	---	---	---	---					
RP11-739N20.2	0	broad.mit.edu	37	1	204363978	204363979	+	RNA	INS	-	-	A			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr1:204363978_204363979insA	ENST00000443515.1	+	0	146																											gatttgtttttcaaaaaaaaaa	0.302													2	4	---	---	---	---					
TPBG	7162	broad.mit.edu	37	6	83075102	83075102	+	Frame_Shift_Del	DEL	C	C	-			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr6:83075102delC	ENST00000369750.3	+	2	1041	c.424delC	c.(424-426)ccfs	p.P142fs	TPBG_ENST00000543496.1_Frame_Shift_Del_p.P142fs|TPBG_ENST00000535040.1_Frame_Shift_Del_p.P142fs			Q13641	TPBG_HUMAN	trophoblast glycoprotein	142					cell adhesion	integral to plasma membrane				central_nervous_system(1)|endometrium(1)|large_intestine(2)|lung(6)|ovary(2)|prostate(1)|skin(1)|stomach(1)	15		all_cancers(76;0.000805)|Acute lymphoblastic leukemia(125;3.85e-06)|all_hematologic(105;0.0017)|all_epithelial(107;0.0897)		BRCA - Breast invasive adenocarcinoma(397;0.107)		CGAGCATCTGCCCAGCCTGCG	0.736													31	33	---	---	---	---					
KCNK7	10089	broad.mit.edu	37	11	65363186	65363186	+	Frame_Shift_Del	DEL	C	C	-			TCGA-SP-A6QD-01A-12D-A35I-08	TCGA-SP-A6QD-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bc13a3fa-5a66-4287-99d1-e5d1990c8898	7cffcf76-88ba-43cb-a4b6-718ca08a9ba0	g.chr11:65363186delC	ENST00000394216.2	-	1	281	c.58delG	c.(58-60)ccfs	p.A20fs	KCNK7_ENST00000394217.2_Frame_Shift_Del_p.A20fs|KCNK7_ENST00000342202.4_Frame_Shift_Del_p.A20fs|KCNK7_ENST00000340313.4_Frame_Shift_Del_p.A20fs	NM_005714.1|NM_033455.1	NP_005705.1|NP_258416.1	Q9Y2U2	KCNK7_HUMAN	potassium channel, subfamily K, member 7	20						integral to membrane	potassium channel activity|voltage-gated ion channel activity			endometrium(1)|liver(1)|lung(1)	3						AGCCCCAGGGCCAGCAAGTGG	0.682													2	4	---	---	---	---