Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
COG5	10466	broad.mit.edu	37	7	107167714	107167714	+	Missense_Mutation	SNP	A	A	G			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr7:107167714A>G	ENST00000393603.2	-	6	870	c.599T>C	c.(598-600)aTa>aCa	p.I200T	COG5_ENST00000475638.2_5'UTR|COG5_ENST00000347053.3_Missense_Mutation_p.I200T|COG5_ENST00000297135.3_Missense_Mutation_p.I200T	NM_001161520.1	NP_001154992.1	Q9UP83	COG5_HUMAN	component of oligomeric golgi complex 5	200					intra-Golgi vesicle-mediated transport|protein transport	cytosol|Golgi membrane|Golgi transport complex|nucleus	protein binding			breast(3)|central_nervous_system(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(4)|lung(17)|ovary(2)|skin(4)|stomach(1)	40						AGCTTTTGTTATCTCTCTACT	0.348000													5	56					0	0	1	0	0
FEM1A	55527	broad.mit.edu	37	19	4793717	4793717	+	Silent	SNP	C	C	A			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr19:4793717C>A	ENST00000269856.3	+	1	1990	c.1851C>A	c.(1849-1851)gcC>gcA	p.A617A	AC005523.2_ENST00000601192.1_RNA	NM_018708.2	NP_061178.1	Q9BSK4	FEM1A_HUMAN	fem-1 homolog a (C. elegans)	617					regulation of ubiquitin-protein ligase activity	cytoplasm	binding|ubiquitin-protein ligase activity	p.A617A(4)		breast(1)|central_nervous_system(2)|endometrium(2)|kidney(1)|large_intestine(2)|lung(5)|ovary(1)|prostate(1)|skin(1)|urinary_tract(1)	17		Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.0139)		AGAAGACGGCCTACGAGCTGC	0.607000													4	44					1	1	1	1	0
WDR33	55339	broad.mit.edu	37	2	128522429	128522429	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr2:128522429G>A	ENST00000322313.4	-	6	757	c.599C>T	c.(598-600)gCa>gTa	p.A200V	WDR33_ENST00000393006.1_Missense_Mutation_p.A200V|WDR33_ENST00000409658.3_Missense_Mutation_p.A200V	NM_018383.4	NP_060853.3	Q9C0J8	WDR33_HUMAN	WD repeat domain 33	200					postreplication repair|spermatogenesis	collagen|nucleus	protein binding			NS(1)|breast(3)|endometrium(2)|kidney(2)|large_intestine(9)|lung(17)|ovary(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	39	Colorectal(110;0.1)			BRCA - Breast invasive adenocarcinoma(221;0.0695)		CTCCTTATGTGCCTGGAACAT	0.413000													17	137					0	0	1	0	0
TMC1	117531	broad.mit.edu	37	9	75420375	75420375	+	Missense_Mutation	SNP	T	T	G			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr9:75420375T>G	ENST00000297784.5	+	18	2184	c.1644T>G	c.(1642-1644)tgT>tgG	p.C548W	TMC1_ENST00000486417.1_3'UTR|TMC1_ENST00000340019.3_Missense_Mutation_p.C548W|TMC1_ENST00000396237.3_Missense_Mutation_p.C548W	NM_138691.2	NP_619636.2	Q8TDI8	TMC1_HUMAN	transmembrane channel-like 1	548					sensory perception of sound	integral to membrane				NS(1)|breast(1)|central_nervous_system(2)|endometrium(2)|kidney(1)|large_intestine(4)|lung(21)|ovary(1)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)	36						TAAGGGCATGTTTTGTGAGGT	0.353000													9	201					0	0	1	0	0
CCT4	10575	broad.mit.edu	37	2	62099293	62099293	+	Missense_Mutation	SNP	T	T	C			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr2:62099293T>C	ENST00000394440.3	-	12	1711	c.1415A>G	c.(1414-1416)aAt>aGt	p.N472S	CCT4_ENST00000461540.2_Intron|CCT4_ENST00000544079.1_Missense_Mutation_p.N442S|CCT4_ENST00000544185.1_Missense_Mutation_p.N322S|AC107081.5_ENST00000425779.1_RNA|CCT4_ENST00000538252.1_Missense_Mutation_p.N416S	NM_006430.3	NP_006421.2	P50991	TCPD_HUMAN	chaperonin containing TCP1, subunit 4 (delta)	472					'de novo' posttranslational protein folding	melanosome|microtubule organizing center|nucleus	ATP binding|unfolded protein binding			breast(1)|large_intestine(2)|lung(6)|ovary(2)	11	Lung NSC(7;0.035)|all_lung(7;0.0691)		LUSC - Lung squamous cell carcinoma(7;6.5e-06)|Epithelial(17;0.0647)|all cancers(80;0.221)			AGAAATGGGATTCAGGCCGGC	0.433000													44	91					0	0	1	0	0
AHCY	191	broad.mit.edu	37	20	32878371	32878371	+	Silent	SNP	G	G	A			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr20:32878371G>A	ENST00000538132.1	-	7	1142	c.756C>T	c.(754-756)gaC>gaT	p.D252D	AHCY_ENST00000217426.2_Silent_p.D280D	NM_001161766.1	NP_001155238.1	P23526	SAHH_HUMAN	adenosylhomocysteinase	280					methylation|xenobiotic metabolic process	cytosol|melanosome	adenosylhomocysteinase activity|protein binding			endometrium(6)|large_intestine(4)|lung(7)|skin(1)|upper_aerodigestive_tract(1)	19						CAAGGATGATGTCAATACAGC	0.587000													5	189					0	0	1	0	0
ZNF844	284391	broad.mit.edu	37	19	12187275	12187275	+	Missense_Mutation	SNP	G	G	C			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr19:12187275G>C	ENST00000439326.3	+	4	1515	c.1340G>C	c.(1339-1341)cGt>cCt	p.R447P	ZNF844_ENST00000441304.2_3'UTR	NM_001136501.1	NP_001129973.1	Q08AG5	ZN844_HUMAN	zinc finger protein 844	447					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding	p.R447P(1)		NS(1)|breast(2)|central_nervous_system(1)|endometrium(2)|kidney(2)|lung(1)|prostate(1)	10						GAGAGAAACCGTATGAGTGTA	0.433000													4	134					0	0	1	0	0
TADA3	10474	broad.mit.edu	37	3	9831245	9831245	+	Missense_Mutation	SNP	C	C	T	rs149462962		TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr3:9831245C>T	ENST00000343450.2	-	4	1059	c.512G>A	c.(511-513)cGc>cAc	p.R171H	TADA3_ENST00000301964.2_Missense_Mutation_p.R171H|TADA3_ENST00000440161.1_Missense_Mutation_p.R171H	NM_133480.1	NP_597814.1	O75528	TADA3_HUMAN	transcriptional adaptor 3	171					estrogen receptor signaling pathway|histone H3 acetylation|positive regulation of transcription, DNA-dependent|regulation of transcription from RNA polymerase II promoter	Ada2/Gcn5/Ada3 transcription activator complex|STAGA complex|transcription factor TFTC complex	ligand-dependent nuclear receptor binding|protein domain specific binding|sequence-specific DNA binding transcription factor activity			endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(4)|lung(4)|skin(2)|upper_aerodigestive_tract(1)	16						CTCAAGTGTGCGGACCTCCTC	0.562000													3	39					0	0	1	0	0
DEFB112	245915	broad.mit.edu	37	6	50011343	50011343	+	Missense_Mutation	SNP	A	A	T			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr6:50011343A>T	ENST00000322246.4	-	2	286	c.287T>A	c.(286-288)aTc>aAc	p.I96N		NM_001037498.1	NP_001032587.1	Q30KQ8	DB112_HUMAN	defensin, beta 112	96					defense response to bacterium	extracellular region				central_nervous_system(1)|large_intestine(3)|lung(12)|ovary(1)|skin(1)|upper_aerodigestive_tract(1)	19	Lung NSC(77;0.042)					GTCCTTTGGGATCCAATTATT	0.413000													12	70					0	0	1	0	0
ALB	213	broad.mit.edu	37	4	74280766	74280766	+	Missense_Mutation	SNP	A	A	G			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr4:74280766A>G	ENST00000295897.4	+	9	1162	c.1073A>G	c.(1072-1074)tAt>tGt	p.Y358C	ALB_ENST00000509063.1_Missense_Mutation_p.Y358C|ALB_ENST00000503124.1_Missense_Mutation_p.Y208C|ALB_ENST00000415165.2_Missense_Mutation_p.Y166C|ALB_ENST00000401494.3_Missense_Mutation_p.Y243C|ALB_ENST00000505649.1_3'UTR	NM_000477.5	NP_000468.1	P02768	ALBU_HUMAN	albumin	358	Albumin 2.				bile acid and bile salt transport|bile acid metabolic process|cellular response to starvation|hemolysis by symbiont of host erythrocytes|lipoprotein metabolic process|maintenance of mitochondrion location|negative regulation of apoptosis|platelet activation|platelet degranulation|sodium-independent organic anion transport|transmembrane transport	extracellular space|platelet alpha granule lumen|protein complex	antioxidant activity|chaperone binding|copper ion binding|DNA binding|drug binding|fatty acid binding|pyridoxal phosphate binding|toxin binding			NS(1)|endometrium(4)|kidney(1)|large_intestine(6)|liver(9)|lung(16)|ovary(3)|prostate(2)|skin(4)|stomach(1)|urinary_tract(1)	48	Breast(15;0.00102)		Epithelial(6;4.8e-05)|OV - Ovarian serous cystadenocarcinoma(6;0.000263)|all cancers(17;0.000472)|Lung(101;0.103)|LUSC - Lung squamous cell carcinoma(112;0.154)		Acenocoumarol(DB01418)|Acitretin(DB00459)|Alfentanil(DB00802)|Aluminium(DB01370)|Auranofin(DB00995)|Bismuth(DB01402)|Captopril(DB01197)|Carboplatin(DB00958)|Cefalotin(DB00456)|Cefazolin(DB01327)|Cefonicid(DB01328)|Cefoperazone(DB01329)|Chlorpheniramine(DB01114)|Chlorpromazine(DB00477)|Ciprofloxacin(DB00537)|Clonazepam(DB01068)|Cloxacillin(DB01147)|Cytarabine(DB00987)|Dantrolene(DB01219)|Diclofenac(DB00586)|Diflunisal(DB00861)|Digitoxin(DB01396)|Estrone(DB00655)|Ethacrynic acid(DB00903)|Etodolac(DB00749)|Flurbiprofen(DB00712)|Gadobenate Dimeglumine(DB00743)|Gatifloxacin(DB01044)|Gliclazide(DB01120)|Halothane(DB01159)|Human Serum Albumin(DB00062)|Hyaluronidase(DB00070)|Ibuprofen(DB01050)|Insulin-detemir(DB01307)|Insulin-glargine(DB01308)|Iodipamide(DB04711)|Ketoprofen(DB01009)|Levamisole(DB00848)|Levothyroxine(DB00451)|Liothyronine(DB00279)|Mefenamic acid(DB00784)|Mephenytoin(DB00532)|Methotrexate(DB00563)|Nortriptyline(DB00540)|Oxazepam(DB00842)|Paclitaxel(DB01229)|Phenprocoumon(DB00946)|Probenecid(DB01032)|Propofol(DB00818)|Pyridoxine(DB00165)|Salicyclic acid(DB00936)|Saquinavir(DB01232)|Serum albumin iodonated(DB00064)|Serum albumin(DB00096)|Sodium lauryl sulfate(DB00815)|Sucralfate(DB00364)|Sulfamethizole(DB00576)|Sulindac(DB00605)|Suprofen(DB00870)|Testosterone(DB00624)|Xanthophyll(DB00137)	TTGTATGAATATGCAAGAAGG	0.373000													5	143					0	0	1	0	0
ARSA	410	broad.mit.edu	37	22	51065311	51065311	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr22:51065311G>A	ENST00000547307.1	-	3	1034	c.629C>T	c.(628-630)gCc>gTc	p.A210V	ARSA_ENST00000356098.5_Missense_Mutation_p.A212V|ARSA_ENST00000395619.3_Missense_Mutation_p.A212V|ARSA_ENST00000216124.5_Missense_Mutation_p.A212V|ARSA_ENST00000395621.3_Missense_Mutation_p.A212V|ARSA_ENST00000547805.1_Missense_Mutation_p.A210V|ARSA_ENST00000453344.2_Missense_Mutation_p.A126V			P15289	ARSA_HUMAN	arylsulfatase A	210						lysosome	arylsulfatase activity|calcium ion binding|cerebroside-sulfatase activity			endometrium(1)|large_intestine(1)|lung(5)|pancreas(1)|skin(1)	9		all_cancers(38;8.8e-15)|all_epithelial(38;1.12e-12)|all_lung(38;3.07e-05)|Breast(42;6.27e-05)|Lung NSC(38;0.000813)|Ovarian(80;0.0221)|Hepatocellular(38;0.0691)|Lung SC(80;0.113)		BRCA - Breast invasive adenocarcinoma(115;0.205)|LUAD - Lung adenocarcinoma(64;0.247)	Micafungin(DB01141)	CTGGGCGTCGGCCATGAGGTC	0.657000													4	157					0	0	1	0	0
HSD17B7P2	158160	broad.mit.edu	37	10	38654432	38654432	+	RNA	SNP	A	A	G	rs2257765		TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr10:38654432A>G	ENST00000494540.1	+	0	599					NR_003086.1																						TCATCTCGCAATGCAAGGAAA	0.453000													3	60					0	0	1	0	0
NUP188	23511	broad.mit.edu	37	9	131760467	131760467	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr9:131760467G>A	ENST00000372577.2	+	31	3410	c.3389G>A	c.(3388-3390)cGc>cAc	p.R1130H		NM_015354.1	NP_056169.1	Q5SRE5	NU188_HUMAN	nucleoporin 188kDa	1130					carbohydrate metabolic process|glucose transport|mRNA transport|protein transport|regulation of glucose transport|transmembrane transport|viral reproduction	nuclear pore	protein binding			breast(2)|central_nervous_system(3)|endometrium(6)|kidney(4)|large_intestine(9)|lung(20)|ovary(6)|prostate(4)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(3)	60						GTGGTGCGTCGCCAGCTCTTT	0.438000													5	363					0	0	1	0	0
ZNF878	729747	broad.mit.edu	37	19	12155673	12155673	+	Missense_Mutation	SNP	A	A	C			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr19:12155673A>C	ENST00000602107.1	-	5	683	c.684T>G	c.(682-684)agT>agG	p.S228R	ZNF878_ENST00000547628.1_Missense_Mutation_p.S181R|CTD-2006C1.2_ENST00000476474.1_RNA|CTD-2006C1.2_ENST00000591898.1_RNA|CTD-2006C1.2_ENST00000591838.1_RNA|CTD-2006C1.10_ENST00000547473.1_Intron			C9JN71	ZN878_HUMAN	zinc finger protein 878	181					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	nucleic acid binding|zinc ion binding			cervix(1)|endometrium(1)|kidney(1)|lung(4)|urinary_tract(1)	8						AACTGGGAAAACTGAATGCTT	0.403000													4	294					0	0	1	0	0
BMS1P20	96610	broad.mit.edu	37	22	22664606	22664606	+	RNA	SNP	A	A	G			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr22:22664606A>G	ENST00000426066.1	+	0	787					NR_027293.1																						GTCTTCATGCAAACTTGGTAT	0.398000													3	26					0	0	1	0	0
ZNF845	91664	broad.mit.edu	37	19	53856730	53856730	+	Silent	SNP	G	G	A			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr19:53856730G>A	ENST00000458035.1	+	4	2919	c.2802G>A	c.(2800-2802)aaG>aaA	p.K934K	ZNF845_ENST00000595091.1_Silent_p.K934K	NM_138374.1	NP_612383.1	Q96IR2	ZN845_HUMAN	zinc finger protein 845	934					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding	p.K934K(3)		endometrium(2)|kidney(10)|lung(7)|pancreas(1)|prostate(1)|skin(2)|stomach(1)|urinary_tract(2)	26						TAATTCATAAGACAATTCATA	0.368000													3	48					0	0	1	0	0
DPPA4	55211	broad.mit.edu	37	3	109050579	109050579	+	Splice_Site	SNP	A	A	G			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr3:109050579A>G	ENST00000335658.6	-	4	445		c.e4+1		DPPA4_ENST00000478791.1_Splice_Site	NM_018189.3	NP_060659.3	Q7L190	DPPA4_HUMAN	developmental pluripotency associated 4							nucleus	protein binding			central_nervous_system(1)|endometrium(2)|large_intestine(1)|lung(17)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	25						TTAAAAAGTTACCTTTTGATT	0.398000													4	65					0	0	1	0	0
PPP1R13L	10848	broad.mit.edu	37	19	45900240	45900240	+	Missense_Mutation	SNP	C	C	G			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr19:45900240C>G	ENST00000418234.2	-	4	353	c.275G>C	c.(274-276)gGc>gCc	p.G92A	PPP1R13L_ENST00000360957.5_Missense_Mutation_p.G92A	NM_001142502.1	NP_001135974.1	Q8WUF5	IASPP_HUMAN	protein phosphatase 1, regulatory subunit 13 like	92	Pro-rich.				apoptosis|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	transcription corepressor activity|transcription factor binding			breast(1)|endometrium(4)|kidney(1)|large_intestine(1)|lung(14)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	26		all_neural(266;0.224)|Ovarian(192;0.231)		OV - Ovarian serous cystadenocarcinoma(262;0.0182)		GGTGTCTGCGCCGTCGGTGGC	0.721000													5	13					0	0	1	0	0
ZNRD1-AS1	80862	broad.mit.edu	37	6	29977342	29977342	+	RNA	SNP	A	A	T	rs116382006	by1000genomes	TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr6:29977342A>T	ENST00000376797.3	-	0	731				ZNRD1-AS1_ENST00000448093.1_RNA|ZNRD1-AS1_ENST00000420251.1_RNA|HLA-J_ENST00000462773.1_RNA|ZNRD1-AS1_ENST00000425604.1_RNA																							TGGGACTGAGAGGCAAGATTT	0.438000													5	85					0	0	1	0	0
PRSS3P2	154754	broad.mit.edu	37	7	142481251	142481251	+	RNA	SNP	A	A	C	rs140137372	by1000genomes	TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr7:142481251A>C	ENST00000603901.1	+	0	325					NR_001296.3																						CAATGACATCATGCTGATCAA	0.522000													4	74					0	0	1	0	0
ZAN	7455	broad.mit.edu	37	7	100369721	100369721	+	RNA	DEL	T	T	-			TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr7:100369721delT	ENST00000542585.1	+	0	5573				ZAN_ENST00000427578.1_RNA|ZAN_ENST00000449052.1_RNA|ZAN_ENST00000546213.1_RNA|ZAN_ENST00000349350.6_RNA|ZAN_ENST00000546292.1_RNA|ZAN_ENST00000443370.1_RNA|ZAN_ENST00000538115.1_RNA|ZAN_ENST00000421100.1_RNA|ZAN_ENST00000348028.3_RNA	NM_003386.1	NP_003377.1	Q9Y493	ZAN_HUMAN	zonadhesin (gene/pseudogene)						binding of sperm to zona pellucida|cell-cell adhesion	integral to membrane|plasma membrane				NS(2)|breast(3)|central_nervous_system(3)|endometrium(21)|kidney(6)|large_intestine(18)|lung(60)|ovary(4)|pancreas(3)|prostate(5)|skin(8)|stomach(3)|upper_aerodigestive_tract(3)	139	Lung NSC(181;0.041)|all_lung(186;0.0581)		STAD - Stomach adenocarcinoma(171;0.19)			ctctaaattcttttttttttt	0.532													3	4	---	---	---	---					
MROH5	389690	broad.mit.edu	37	8	142459777	142459778	+	RNA	INS	-	-	A	rs144781370	by1000genomes	TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr8:142459777_142459778insA	ENST00000430863.1	-	0	2629_2630					NM_207414.2	NP_997297.2			maestro heat-like repeat family member 5																		GCAGACAGGCCAGCAGTGTGGT	0.678													4	2	---	---	---	---					
DCHS1	8642	broad.mit.edu	37	11	6662745	6662746	+	In_Frame_Ins	INS	-	-	CAG	rs56194704		TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chr11:6662745_6662746insCAG	ENST00000299441.3	-	2	510_511	c.99_100insCTG	c.(97-102)ctgggc>ctCTGgggc	p.33_34LG>LWG		NM_003737.2	NP_003728.1	Q96JQ0	PCD16_HUMAN	dachsous cadherin-related 1	33					calcium-dependent cell-cell adhesion|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding	p.L33_G34insL(1)		breast(3)|central_nervous_system(1)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(4)|kidney(4)|large_intestine(16)|liver(1)|lung(41)|ovary(4)|pancreas(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(6)|urinary_tract(4)	103		Medulloblastoma(188;0.00263)|all_neural(188;0.026)		Epithelial(150;6.35e-09)|BRCA - Breast invasive adenocarcinoma(625;0.135)		ACCCCAGCCCCcagcagcagca	0.639													5	5	---	---	---	---					
SHROOM4	57477	broad.mit.edu	37	X	50350711	50350713	+	In_Frame_Del	DEL	TCC	TCC	-	rs6614551		TCGA-QR-A70Q-01A-13D-A35D-08	TCGA-QR-A70Q-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ceb88eff-474b-4640-bb0f-c69066b69dac	e2fe5304-a8b9-49ba-997c-7c930b54f411	g.chrX:50350711_50350713delTCC	ENST00000376020.2	-	6	3454_3456	c.3429_3431delGGA	c.(3427-3432)gaa>ga	p.EE1149del	SHROOM4_ENST00000289292.7_In_Frame_Del_p.EE1149del|SHROOM4_ENST00000460112.3_In_Frame_Del_p.EE1033del	NM_020717.3	NP_065768.2	Q9ULL8	SHRM4_HUMAN	shroom family member 4	1149	Glu-rich.				actin filament organization|brain development|cell morphogenesis|cognition	apical plasma membrane|basal plasma membrane|internal side of plasma membrane|nucleus	actin filament binding			breast(3)|central_nervous_system(1)|cervix(1)|endometrium(6)|kidney(5)|large_intestine(6)|liver(1)|lung(20)|ovary(1)|prostate(4)|skin(3)|upper_aerodigestive_tract(1)	52	Ovarian(276;0.236)					ctcttcctcttcctcttcttctt	0.547													4	5	---	---	---	---