Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ANKRD36C	400986	broad.mit.edu	37	2	96593000	96593000	+	Missense_Mutation	SNP	A	A	G	rs111976783		TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr2:96593000A>G	ENST00000456556.1	-	28	1985	c.1901T>C	c.(1900-1902)aTa>aCa	p.I634T						ankyrin repeat domain 36C									p.I634T(1)		breast(1)|endometrium(8)|kidney(5)|lung(4)	18						TTCTGTGGCTATATTTGAAAC	0.338000													3	54					0	0	1	0	0
ANKRD20A8P	729171	broad.mit.edu	37	2	95522772	95522772	+	RNA	SNP	T	T	C			TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr2:95522772T>C	ENST00000432432.2	-	0	255					NR_040113.1													p.E49G(1)									GCGCTCCACCTCCGCGGCGTC	0.682000													3	51					0	0	1	0	0
MST1L	11223	broad.mit.edu	37	1	17083685	17083685	+	RNA	SNP	C	C	A	rs3197973	by1000genomes	TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr1:17083685C>A	ENST00000455405.2	-	0	903																											ACTGTACTTACAAGTTTTGTC	0.403000													4	21					0.00198382	0.00198382	1	1	0
NBPF1	55672	broad.mit.edu	37	1	16918653	16918653	+	Splice_Site	SNP	C	C	T			TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr1:16918653C>T	ENST00000430580.2	-	6	853		c.e6+1			NM_017940.3	NP_060410.2	Q3BBV0	NBPF1_HUMAN	neuroblastoma breakpoint family, member 1							cytoplasm									UCEC - Uterine corpus endometrioid carcinoma (279;0.00459)|BRCA - Breast invasive adenocarcinoma(304;7.52e-06)|COAD - Colon adenocarcinoma(227;1.05e-05)|Kidney(64;0.00016)|KIRC - Kidney renal clear cell carcinoma(64;0.00258)|STAD - Stomach adenocarcinoma(196;0.00644)|READ - Rectum adenocarcinoma(331;0.0649)|Lung(427;0.179)		TCTTAACTTACTGTTGTGAAA	0.418000													5	29					0	0	1	0	0
NASP	4678	broad.mit.edu	37	1	46073584	46073584	+	Missense_Mutation	SNP	T	T	G			TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr1:46073584T>G	ENST00000350030.3	+	6	1088	c.1001T>G	c.(1000-1002)gTa>gGa	p.V334G	NASP_ENST00000402363.3_Missense_Mutation_p.V336G|NASP_ENST00000372052.4_Intron|NASP_ENST00000351223.3_Intron|NASP_ENST00000537798.1_Missense_Mutation_p.V270G	NM_002482.3	NP_002473.2	P49321	NASP_HUMAN	nuclear autoantigenic sperm protein (histone-binding)	334	Glu-rich (acidic).				blastocyst development|cell cycle|cell proliferation|DNA replication|histone exchange|protein transport	cytoplasm|nucleus	Hsp90 protein binding			breast(1)|cervix(1)|endometrium(1)|large_intestine(2)|lung(6)|ovary(1)|pancreas(1)|prostate(3)|skin(1)	17	Acute lymphoblastic leukemia(166;0.155)|Lung SC(450;0.211)					GAACAACTGGTAGGTCAAGAA	0.542000													3	41					0	0	1	0	0
ZC3H6	376940	broad.mit.edu	37	2	113089358	113089358	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr2:113089358G>A	ENST00000409871.1	+	12	3264	c.2863G>A	c.(2863-2865)Ggt>Agt	p.G955S	ZC3H6_ENST00000343936.4_Missense_Mutation_p.G955S	NM_198581.2	NP_940983.2	P61129	ZC3H6_HUMAN	zinc finger CCCH-type containing 6	955							nucleic acid binding|zinc ion binding			central_nervous_system(2)|endometrium(3)|kidney(3)|large_intestine(9)|lung(12)|ovary(4)|prostate(2)	35						AGACTCACACGGTTCAGGAGC	0.393000													3	25					0	0	1	0	0
SSTR3	6753	broad.mit.edu	37	22	37602845	37602845	+	Missense_Mutation	SNP	C	C	T			TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr22:37602845C>T	ENST00000328544.3	-	2	1531	c.998G>A	c.(997-999)cGc>cAc	p.R333H	SSTR3_ENST00000402501.1_Missense_Mutation_p.R333H	NM_001051.3	NP_001042.1	P32745	SSR3_HUMAN	somatostatin receptor 3	333					G-protein signaling, coupled to cyclic nucleotide second messenger|induction of apoptosis by hormones|negative regulation of cell proliferation	integral to plasma membrane|nonmotile primary cilium	somatostatin receptor activity	p.R333H(1)		NS(1)|breast(1)|kidney(1)|large_intestine(1)|lung(9)|ovary(1)	14						GCGCACACGGCGGGAGGGCCG	0.667000													5	43					0	0	1	0	0
PTCH2	8643	broad.mit.edu	37	1	45288335	45288335	+	Nonsense_Mutation	SNP	G	G	A			TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr1:45288335G>A	ENST00000447098.2	-	22	3375	c.3364C>T	c.(3364-3366)Cag>Tag	p.Q1122*	PTCH2_ENST00000372192.3_Nonsense_Mutation_p.Q1122*	NM_001166292.1	NP_001159764.1	Q9Y6C5	PTC2_HUMAN	patched 2	1122					protein complex assembly|spermatogenesis	integral to plasma membrane	hedgehog receptor activity			NS(2)|breast(6)|central_nervous_system(3)|cervix(1)|endometrium(5)|kidney(2)|large_intestine(6)|lung(19)|ovary(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	50	Acute lymphoblastic leukemia(166;0.155)					TTGTACATCTGTATCACCTGT	0.622000									Basal Cell Nevus syndrome				4	82					0	0	1	0	0
RRN3P2	653390	broad.mit.edu	37	16	29110458	29110458	+	RNA	SNP	T	T	C	rs151074589	by1000genomes	TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr16:29110458T>C	ENST00000564580.1	+	0	1131																		p.W375R(25)									GAATTTTGAGTGGATAGTGAT	0.328000													4	89					0	0	1	0	0
FOLH1B	219595	broad.mit.edu	37	11	89392753	89392753	+	RNA	SNP	A	A	C			TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr11:89392753A>C	ENST00000532352.1	+	0	576							Q9HBA9	FOH1B_HUMAN	folate hydrolase 1B						proteolysis	cytoplasm	dipeptidase activity|metal ion binding|metallopeptidase activity			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(2)|large_intestine(7)|lung(26)|ovary(4)|skin(4)|urinary_tract(2)	48						TTCTCTACTCAGACCCTGCTG	0.453000													3	27					0	0	1	0	0
SPTBN2	6712	broad.mit.edu	37	11	66475224	66475224	+	Silent	SNP	C	C	T	rs145249947	byFrequency	TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr11:66475224C>T	ENST00000533211.1	-	13	1747	c.1416G>A	c.(1414-1416)acG>acA	p.T472T	SPTBN2_ENST00000529997.1_Silent_p.T472T|SPTBN2_ENST00000309996.2_Silent_p.T472T			O15020	SPTN2_HUMAN	spectrin, beta, non-erythrocytic 2	472					actin filament capping|axon guidance|cell death|vesicle-mediated transport	cytosol|spectrin	actin binding|structural constituent of cytoskeleton			autonomic_ganglia(1)|breast(1)|central_nervous_system(4)|cervix(1)|endometrium(10)|kidney(5)|large_intestine(15)|liver(1)|lung(22)|ovary(2)|pancreas(1)|prostate(3)|skin(5)|upper_aerodigestive_tract(2)|urinary_tract(1)	74						CCACGATGTCCGTCTCAATGG	0.672000													5	67					0	0	1	0	0
AGBL2	79841	broad.mit.edu	37	11	47712201	47712201	+	Nonsense_Mutation	SNP	C	C	T			TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr11:47712201C>T	ENST00000525123.1	-	10	1343	c.1058G>A	c.(1057-1059)tGg>tAg	p.W353*	AGBL2_ENST00000529712.1_5'UTR|AGBL2_ENST00000357610.3_Nonsense_Mutation_p.W353*|AGBL2_ENST00000528244.1_Nonsense_Mutation_p.W315*|AGBL2_ENST00000298861.4_Nonsense_Mutation_p.W353*	NM_024783.3	NP_079059.2	Q5U5Z8	CBPC2_HUMAN	ATP/GTP binding protein-like 2	353					proteolysis	cytosol	metallocarboxypeptidase activity|zinc ion binding			NS(1)|endometrium(5)|kidney(1)|large_intestine(8)|liver(1)|lung(14)|ovary(2)|prostate(1)|skin(1)	34						TTCTCTCCTCCAGCCAATATT	0.453000													22	20					0	0	1	0	0
KCNN2	3781	broad.mit.edu	37	5	113698631	113698632	+	In_Frame_Ins	INS	-	-	GCC	rs34838882	by1000genomes	TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr5:113698631_113698632insGCC	ENST00000512097.3	+	2	1177_1178	c.159_160insGCC	c.(157-162)gcccgc>gcGCCccgc	p.53_54AR>APR	KCNN2_ENST00000264773.3_In_Frame_Ins_p.53_54AR>APR			Q9H2S1	KCNN2_HUMAN	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	53	Poly-Ala.					integral to membrane	calmodulin binding|small conductance calcium-activated potassium channel activity			breast(1)|endometrium(5)|kidney(2)|large_intestine(7)|lung(21)|ovary(2)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	45		all_cancers(142;2.86e-05)|all_epithelial(76;9.33e-06)|Prostate(80;0.00955)|Ovarian(225;0.0444)|Breast(839;0.159)|Lung NSC(810;0.174)|all_lung(232;0.206)		OV - Ovarian serous cystadenocarcinoma(64;1.89e-08)|Epithelial(69;2.04e-08)|all cancers(49;3.74e-06)|COAD - Colon adenocarcinoma(37;0.142)|Colorectal(14;0.195)		CTGCAGCCGCTGCCGCCGCCGC	0.703													5	8	---	---	---	---					
ESRRAP2	144832	broad.mit.edu	37	13	21835723	21835728	+	RNA	DEL	GGCGAG	GGCGAG	-			TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr13:21835723_21835728delGGCGAG	ENST00000427890.1	+	0	61																											GATGGACTGAGGCGAGGGGTGGGACT	0.646													2	4	---	---	---	---					
PABPN1	8106	broad.mit.edu	37	14	23791016	23791016	+	Frame_Shift_Del	DEL	C	C	-			TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr14:23791016delC	ENST00000397276.2	+	1	351	c.338delC	c.(337-339)gcfs	p.A113fs	BCL2L2-PABPN1_ENST00000557008.1_Intron|AL049829.1_ENST00000594872.1_Frame_Shift_Del_p.W34fs|PABPN1_ENST00000216727.4_Frame_Shift_Del_p.A113fs|BCL2L2-PABPN1_ENST00000553781.1_Intron|PABPN1_ENST00000556821.1_5'UTR					poly(A) binding protein, nuclear 1											large_intestine(1)|lung(1)|ovary(2)	4	all_cancers(95;6.69e-06)			GBM - Glioblastoma multiforme(265;0.00643)		GGGGACGGCGCCATTGAGGAC	0.771													2	4	---	---	---	---					
NPIPA8	101059953	broad.mit.edu	37	16	18441114	18441116	+	Splice_Site	DEL	CAC	CAC	-			TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr16:18441114_18441116delCAC	ENST00000339303.5	-	1	15		c.e1+1							nuclear pore complex interacting protein family, member A8																		CGGCCATACTCACCACTGGGACT	0.709													4	5	---	---	---	---					
HOMER3	9454	broad.mit.edu	37	19	19042905	19042906	+	Frame_Shift_Del	DEL	GA	GA	-	rs80104014	byFrequency	TCGA-QR-A703-01A-11D-A35D-08	TCGA-QR-A703-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7d9bdbe4-49c3-4010-8e42-8673307e02c7	eed74c07-ea35-4095-becc-cd65cd2f1f25	g.chr19:19042905_19042906delGA	ENST00000539827.1	-	6	1221_1222	c.569_570delTC	c.(568-570)tfs	p.F190fs	HOMER3_ENST00000221222.11_Frame_Shift_Del_p.F190fs|HOMER3_ENST00000594439.1_Frame_Shift_Del_p.F154fs|HOMER3_ENST00000594794.1_Intron|HOMER3_ENST00000433218.2_Frame_Shift_Del_p.F190fs|HOMER3_ENST00000392351.3_Frame_Shift_Del_p.F190fs|HOMER3_ENST00000355887.6_Frame_Shift_Del_p.F190fs|AC002985.3_ENST00000596918.1_Intron|HOMER3_ENST00000542541.2_Frame_Shift_Del_p.F190fs			Q9NSC5	HOME3_HUMAN	homer homolog 3 (Drosophila)	190					metabotropic glutamate receptor signaling pathway|protein targeting	cell junction|cytoplasm|postsynaptic density|postsynaptic membrane	protein binding			endometrium(3)|large_intestine(1)|lung(5)|upper_aerodigestive_tract(1)	10			Epithelial(12;0.0107)			CCTGCAGTGCGAAAAACTCGGC	0.688													2	4	---	---	---	---